Abstract: The present invention relates to a reconstructed skin model, characterized in that it comprises an epidermis equivalent on a support, the said epidermis equivalent comprising at least keratinocytes and at least induced or noninduced precursors of Langerhans' cells, as well as the process for preparing the said skin equivalent.The invention also relates to an epidermis equivalent, characterized in that it comprises at least keratinocytes and at least induced or noninduced precursors of Langerhans' cells and to the process for preparing it.

Abstract: Stable and homogeneous, topically applicable cosmetic compositions well suited for artificially tanning human skin, comprise a storage-stable, ultrafine oil-in-water emulsion, devoid of lipid vesicles, containing an effective artificial tanning amount of dihydroxyacetone, and further wherein the average particle size of the globules comprising the oily phase of the emulsion characteristically ranges from 100 nm to 1,000 nm.

Abstract: The invention relates to a composition, in particular a cosmetic composition, and more particularly one for dyeing keratin fibers, this composition containing at least one substance P antagonist in order to reduce or even eliminate the irritant effects of the dyes and/or pigments and/or dye precursors used during this dyeing. The substance P antagonist may form part of the dye composition itself or may be contained in a composition which is applied prior to the application of the dye composition.

Abstract: The invention relates to the use of a salt of an alkaline-earth metal in a cosmetic, pharmaceutical, veterinary and/or dermatological composition for treating, in particular, sensitive skins. It relates, in addition, to the use of a salt of an alkaline-earth metal for preventing and/or combating rosacea and/or skin irritation and/or dartre and/or pudic erythema and/or dysesthetic sensation and/or sensation of inflammation and/or pruritus of the skin and/or of the mucous membranes. The salt is in particular strontium nitrate or chloride.

Abstract: Topically applicable pharmaceutical/dermatological/cosmetic compositions well suited for the therapeutic treatment or care of sensitive human skin, hair, mucous membranes, nails and/or the scalp, in particular for reducing or avoiding the skin-irritant side effects of a variety of bioactive agents, for example the .alpha.-hydroxy and .beta.-hydroxy acids, comprise a therapeutically/cosmetically effective amount of at least one bradykinin antagonist.

Abstract: Photoprotective/cosmetic compositions well suited for enhanced photoprotection of human skin and/or hair, as well as of a wide variety of other photosensitive materials and substrates, e.g., inorganic or organic glasses, plastics or the like, against the deleterious effects of UV-A and UV-B irradiation, particularly solar radiation, comprise a photoprotecting effective amount of a novel insoluble benzalmalonate/phenylcyanoacrylate-substituted s-triazine compound having the structural formula (I): ##STR1## in which R.sub.1, R.sub.1 ' and R.sub.

Abstract: Topically applicable sunscreen/cosmetic compositions well suited for enhanced photoprotection of human skin and/or hair against the damaging effects of UV-A and UV-B irradiation, particularly solar radiation, comprise a photoprotecting effective amount of a novel cinnamonitrile-substituted polyorganosiloxane/polyorganosilane having one of the formulae (1) to (3): ##STR1## wherein A is a monovalent cinnamonitrile radical which comprises an alkylene or alkyleneoxy bridging group, which is bonded directly to a silicon atom, and which has the formula (4): ##STR2##

Abstract: Cosmetic compositions, well suited for the permanent deformation of keratinous fibers, for example permanent waves for topical application to human hair, comprise at least one reducing agent and/or at least one oxidizing agent other than a peroxide or cresol, at least one of reducing and/or oxidizing agents normally eliciting a skin irritating side effect, and an effective skin irritant-attenuating/eliminating amount of at least one substance P antagonist and/or at least one CGRP antagonist, in a physiologically acceptable medium therefor.

Abstract: The present invention relates to the use of at least one extract from at least one non-photosynthetic filamentous bacterium as substance P antagonist in a cosmetic composition or for the preparation of a pharmaceutical composition. The invention also relates to the use of at least one extract from at least one non-photosynthetic filamentous bacterium in a cosmetic composition or for the preparation of a pharmaceutical composition intended for the treatment of disorders associated with an excess in the synthesis and/or in the release of substance P. The invention additionally relates to various compositions containing an extract from at least one non-photosynthetic filamentous bacterium and to a cosmetic treatment process.

Abstract: Cutaneous perspiration in a human subject is prevented and/or controlled by topically applying to the skin of an individual in need of such treatment, an effective antiperspirant amount of at least one substance P antagonist.

Abstract: Topically applicable, photobluing-resistant cosmetic/dermatological compositions, well suited for improved photoprotection of human skin and/or the scalp against the damaging effects of UV-A and UV-B irradiation and/or for the therapeutic treatment of a disease state of the skin or scalp, comprise (a) an effective photoprotective amount of at least one titanium dioxide (nano) pigment and (b) an effective photobluing-reducing amount of at least one benzotriazole silicone.

Abstract: Variously pure ribosomal fractions separated from at least one nonphotosynthetic filamentous bacterium are well suited for formulation into a variety of cosmetic/pharmaceutical compositions, for example for the immunostimulation of the immune system of the skin.

Abstract: Topically applicable UVA photoprotective cosmetic/dermatological compositions comprise an effective photoprotecting amount of at least one UVA screening agent substituted by at least one optionally neutralized sulfo functional group, and an effective UVA photoprotecting-enhancing amount of at least one otherwise non-UVA photoprotecting iron chelating agent, thereby imparting a synergistic protection factor (PF) effect thereto, in a cosmetically/dermatologically acceptable topical vehicle, carrier or diluent therefor.

Abstract: Novel photoprotective/cosmetic photocoloration-resistant compositions, well suited for the photoprotection of human skin and/or hair, comprise an effective UV-screening amount of at least one titanium dioxide nanopigment and an effective photobluing-reducing amount of at least one ionic amphiphilic lipid which comprises an acylamino acid, in a cosmetically acceptable vehicle therefor.

Abstract: Improvedly water-resistant sunscreen/cosmetic compositions, well suited for the prolonged UV-photoprotection of human skin and hair, comprise a cosmetically acceptable oil-in-water emulsion containing (i) at least one hydrophilic compound that screens ultraviolet irradiation and which comprises at least one optionally neutralized acid functional group, for example at least one optionally neutralized sulfonic acid or carboxylic acid functional group, and (ii) at least one insoluble filler material that is both inert with respect to said at least one hydrophilic acid compound (i) and an adsorbent therefor.

Abstract: Stable and homogeneous, topically applicable sunscreen/cosmetic compositions well suited for the photoprotection of human skin and/or hair against the damaging effects of UV-A and/or UV-B irradiation, particularly solar radiation, and which display excellent transparency on the skin, comprise a storage-stable, ultrafine oil-in-water emulsion of a photoprotecting effective amount of homogeneously and finely dispersed particulates of at least one inorganic nanopigment which comprises a metal oxide, for example titanium dioxide, wherein the average particle size of the globules comprising the oily phase of the emulsion characteristically range from 100 nm to 1,000 nm.

Abstract: Topically applicable sunscreen/cosmetic compositions well suited for enhanced photoprotection of human skin and/or hair against the damaging effects of UV-A and UV-B irradiation, particularly solar radiation, comprise a photoprotecting synergistically effective amount of (i) 1,4-benzene ?di(3-methylidene-10-camphosulfonic)! acid, optionally either partially or totally neutralized, together with a photoprotecting synergistically effective amount of (ii) a benzotriazole-substituted polyorganosiloxane, in a cosmetically acceptable vehicle, diluent or carrier therefor.

Abstract: The invention relates to the use of a substance P antagonist for the preparation of a pharmaceutical composition, especially for topical application, for treating skin reddening of neurogenic origin, and especially rosacea and pudic erythema.The substance P antagonist may be a peptide compound or a nitrogen-containing compound or a nitrogen-containing, sulphur-containing or oxygen-containing heterocyclic compound.

Abstract: The present invention relates to artificial tanning cosmetic compositions comprising, in a cosmetically acceptable water-in-silicone emulsion, DHA, at least one mono- or dihydric alcohol and a silicone-containing polydimethylsiloxane emulsifying agent of the following formula (I) or (II): ##STR1##

Abstract: Methods and compositions for affecting the growth of hair which comprise hair growth promoting amounts of peptides containing the Lys-Pro-Val sequence not preceded by a histidine, valine or derivative thereof, are provided.