Abstract: This invention provides a method of forming semiconductor films on dielectrics at temperatures below 400° C. Semiconductor films are required for thin film transistors (TFTs), on-chip sensors, on-chip micro-electromechanical systems (MEMS) and monolithic 3D-integrated circuits. For these applications, it is advantageous to form the semiconductor films below 400° C. because higher temperatures are likely to destroy any underlying devices and/or substrates. This invention successfully achieves low temperature growth of germanium films using diboran. First, diboran gas is supplied into a reaction chamber at a temperature below 400° C. The diboran decomposes itself at the given temperature and decomposed boron is attached to the surface of a dielectric, for e.g., SiO2, forming a nucleation site and/or a seed layer. Second, source gases for semiconductor film formation, for e.g., SiH4, GeH4, etc., are supplied into the chamber, thereby forming a semiconductor film.
Abstract: Novel double and triple fusion reporter gene constructs harboring distinct imagable reporter genes are provided, as well as applications for the use of such double and triple fusion constructs in living cells and in living animals using distinct imaging technologies.
Abstract: An improved method and apparatus for respiratory audio-visual biofeedback are disclosed. A guide patterned after a breathing cycle comfortable to the patient serves as a target. The target is displayed as a bar moving vertically upward during inhale and vertically downward during exhale, between fixed end ex-hale and end in-hale limits. The patient's current respiratory position is also displayed as a bar, oriented parallel to the target bar so that the difference between the current position and the target position is easy for the patient to see.
Type:
Grant
Filed:
October 4, 2006
Date of Patent:
June 7, 2011
Assignee:
Stanford University
Inventors:
Paul Keall, Rohini George, Radhe Mohan, Keith Miller, Theodore Chung
Abstract: An agent that receives an input event and outputs Emotion_Response messages based on personality trait indices and emotional state indices is disclosed. The agent has a social response generator that receives an input event, an output from an emotional state register and an output from a predefined personality trait register, and updates at least one of a current state of the emotional state register or a Social_Response message stored an event buffer. The agent has an emotion generator that outputs an Emotion_Response message based on at least one of the Social_Response message stored in the event buffer, one or more outputs of the predefined personality trait register, or one or more outputs of the emotional state register. The agent operates within an environment server that provides contextual environment that facilitates interaction amongst a group of agents, which receive input events from the contextual environment and outputs emotional response messages thereto.
Abstract: A cyclic carbonate monomer, including: wherein R1, R2, and R3 are independently selected from the group consisting of H, linear or branched, substituted or unsubstituted alkyl; R10 is a connecting group selected from the group consisting of linear or branched, substituted or unsubstituted alkyl, heteroalkyl, cycloalkyl, heterocyclic, aryl and heteroaryl; R4 is an optional bridging group selected from the group consisting of linear or branched, substituted or unsubstituted alkyl, heteroalkyl, cycloalkyl, heterocyclic, aryl and heteroaryl; Z is selected from the group consisting of O, NH, NR, and S; G is a guanidine group; and P is a protecting group. The cylic carbonate monomer can be reacted with an initiator including a drug, drug candidate, probe or other molecule of interest to form an oligomer with the molecule of interest attached to one end of a carbonate backbone and guanidine groups attached to the carbonate backbone.
Type:
Grant
Filed:
April 30, 2009
Date of Patent:
May 10, 2011
Assignees:
International Business Machines Corporation, Stanford University
Inventors:
Christina Cooley, James Lupton Hedrick, Matthew Kiesewetter, Fredrik Nederberg, Brian Trantow, Robert Waymouth, Paul Wender
Abstract: Briefly described, embodiments of this disclosure include polynucleotides that encode mutant Cnidarian luciferases that exhibit modulated properties as compared to the corresponding wild-type luciferases, and the modulated properties include at least one of: modulated stability; enhanced light output; and modulated emission maximum. Embodiments of the present disclosure also include polypeptides or fragments thereof encoded by the polynucleotides, constructs including the polynucleotide, expression cassettes, cells, methods of producing the polynucleotides and polypeptides, antibodies, transgenic cells and/or animals, kits, and the like.
Type:
Grant
Filed:
September 6, 2006
Date of Patent:
May 10, 2011
Assignees:
Stanford University, Regents of University of California
Inventors:
Sanjiv S. Gambhir, Andreas M. Loening, Anna M. Wu
Abstract: A method and apparatus includes detecting lightning induced electromagnetic pulses and determining a physical property of an underground structure based on the lightning induced electromagnetic pulses. In some embodiments, an apparatus includes an antenna, a low noise amplifier, a processor, cable, and a transmitter. The antenna includes three substantively perpendicular loops of electrical conductors. The processor is configured to condition the amplified signal. The cable is about 100 meters in length and connects the low noise amplifier to the processor. The transmitter is configured to send conditioned data to a data aggregation system.
Type:
Application
Filed:
August 26, 2010
Publication date:
April 28, 2011
Applicant:
Stanford University
Inventors:
Ivan Richard Linscott, Timothy Chevalier, Umran S. Inan, David Strauss
Abstract: A method of eliciting analgesia in a human subject by Transcranial Electrical Stimulation (TCES, herein “TES”) is provided. Electrodes secured to the skin of the subject's head at particular sites provide an electrical current that includes a direct current combined with rectangular AC current pulses delivered at a particular frequency of between 10 and 100 Hz. In an embodiment the total current transmitted, a sum of the DC component and a Mean Absolute Deviation (MAD) of the current pulses, has a value between 0.2 and 20 mA. The method is used to produce analgesia during perioperative period, surgery and the post-operative procedure. It can also be used for treating acute chronic pain and a wide variety of other conditions.
Abstract: A displacement and velocity based prospective cine CT (PDV CT) method is disclosed for starting image acquisition if the displacement and velocity are simultaneously within predetermined tolerances, thus essentially sorting 2D CT images in a five dimensional parameter space, where displacement and the sign of the velocity are used for the temporal sorting, replacing the use of either phase or displacement as the temporal parameter during retrospective sorting, with velocity as a separate parameter correlating to some parameter of the system, e.g. the airflow rate, making it possible to do the image sorting in real-time.
Abstract: A method is provided for producing a measuring transducer in order to transform at least one physical variable into at least one electric variable. A plurality of planar, insulating and conductive layers are respectively structured according to predefineable models which are adapted to each other and which are assembled in order to form a multi-layered arrangement.
Type:
Grant
Filed:
December 8, 2004
Date of Patent:
February 15, 2011
Assignees:
ABB AG, Stanford University
Inventors:
Peter Krippner, Fritz B. Prinz, Sangkyun Kang, Tibor Fabian
Abstract: The invention concerns a polymer synthesis apparatus (20) for building a polymer chain including a head assembly (21) having an array of nozzles (22) with each nozzle coupled to a reservoir (23) of liquid reagent (24), and a base assembly (25) having an array of reaction wells (26). A transport mechanism (27) aligns the reaction wells (26) and selected nozzles (22) for deposition of the liquid reagent (24) into selected reaction wells (26). A sliding seal (30) is positioned between the head assembly (21) and the base assembly (25) to form a common chamber (31) enclosing both the reaction well (26) and the nozzles (22) therein.
Type:
Grant
Filed:
July 22, 2008
Date of Patent:
December 28, 2010
Assignee:
The Board of Trustees of Leland Junior Stanford University
Abstract: Techniques for a receiver includes a low noise amplifier, a Q-enhanced bandpass filter on a chip, and an analog to digital converter (ADC) at a sub-sampling speed suitable for an intermediate frequency (IF) signal. In some embodiments, a temperature compensation circuit is included. The receiver has an effective noise level less than 7 dB. In some embodiments a 1-bit ADC is used. In some of these embodiments, one or more switches in the ADC are inverted to cancel charge injection.
Type:
Application
Filed:
May 28, 2010
Publication date:
December 2, 2010
Applicant:
Stanford University
Inventors:
Carsten Barth, Umran S. Inan, Ivan Richard Linscott
Abstract: Briefly described, embodiments of this disclosure include bioluminescence resonance energy transfer (BRET) systems, methods of detecting a protein-protein interaction, noninvasive methods for detecting the interaction of a first protein with a second protein within a living animal, methods to determine the efficacy of a test compound administered to modulate the interaction of a first protein with a second protein in a living animal, BRET vectors, kits relating to each of the above, transgenic cell or progeny thereof and/or animals relating to each of the above, and the like.
Abstract: Fast digital implementations of the second generation curvelet transform for use in data processing are disclosed. One such digital transformation is based on unequally-spaced fast Fourier transforms (USFFT) while another is based on the wrapping of specially selected Fourier samples. Both digital transformations return a table of digital curvelet coefficients indexed by a scale parameter, an orientation parameter, and a spatial location parameter. Both implementations are fast in the sense that they run in about O(n2 log n) flops for n by n Cartesian arrays or about O(N log N) flops for Cartesian arrays of size N=n3; in addition, they are also invertible, with rapid inversion algorithms of about the same complexity.
Type:
Grant
Filed:
April 7, 2006
Date of Patent:
November 23, 2010
Assignees:
California Institute of Technology, Stanford University
Inventors:
Emmanuel Candes, David Donoho, Laurent Demanet
Abstract: A deliverable four dimensional (4D) intensity modulated radiation therapy (IMRT) planning method is disclosed, for delivery using a linear accelerator with a dynamic multi-leaf collimator (DMLC). A 4D computed tomography (CT) scan is used for segmenting tumor anatomy on a reference phase of periodic motion of the tumor. Deformable registration of the 4D CT data is used to generate corresponding anatomical structures on other phases. Preferably, the collimator for each beam position is aligned using the gross tumor volume (GTV) centroid motion corresponding to the periodic motion of the tumor, as determined from the two dimensional (2D) projection of a given beam position. A deliverable IMRT plan is created on the 4D CT image set in which the MLC leaf positions and beam on/off status can vary as a function of respiratory phase by solving a four dimensional optimization problem. The mechanical constraints of the MLC leaves are included in the optimization.
Type:
Grant
Filed:
August 6, 2008
Date of Patent:
November 16, 2010
Assignee:
Stanford University
Inventors:
Paul J. Keall, Yelin Suh, Elisabeth Weiss
Abstract: Briefly described, embodiments of this disclosure include phosphorylation sensing systems, methods of detecting phosphorylation, noninvasive methods for detecting the interaction of a first protein with a second protein within a living animal, fusion proteins including the phosphorylation sensing system, vectors including the phosphorylation sensing system, kits including the phosphorylation sensing system, transgenic cells including the phosphorylation sensing system, and the like are provided.
Type:
Grant
Filed:
May 23, 2007
Date of Patent:
November 16, 2010
Assignee:
Stanford University
Inventors:
Sanjiv S. Gambhir, Ramasamy Paulmurugan
Abstract: A method, apparatus and computer program product may be provided for generating a plurality of compressed feature descriptors that can be represented by a relatively small number of bits, thereby facilitating transmission and storage of the feature descriptors. A method, apparatus and computer program product may also be provided for permitting a compressed representation of a feature descriptor to be compared with a plurality of compressed representations of feature descriptors of respective predefined features. By permitting the comparison to be performed utilizing compressed representations of feature descriptors, a respective feature descriptor may be identified without having to first decompress the feature descriptor, thereby potentially increasing the efficiency with which feature descriptors may be identified.
Type:
Application
Filed:
November 12, 2009
Publication date:
September 9, 2010
Applicants:
NOKIA CORPORATION, STANFORD UNIVERSITY
Inventors:
Radek Grzeszczuk, Vijay Chandrasekhar, Gabriel Takacs, Bernd Girod
Abstract: A method of forming a device with a piezoresistor is disclosed herein. In one embodiment, the method includes providing a substrate, etching a trench in the substrate to form a vertical wall, growing a piezoresistor layer epitaxially on the vertical wall, and separating the vertical wall from an underlying layer of the substrate that extends along a horizontal plane such that the piezoresistor layer is movable with respect to the underlying layer within the horizontal plane.
Type:
Application
Filed:
January 13, 2009
Publication date:
July 15, 2010
Applicants:
Stanford University, Robert Bosch GmbH
Inventors:
Gary Yama, Beth Pruitt, Arnoldus Alvin Barlian
Abstract: This invention involves methods and materials for conferring a direct proliferative advantage on a genetically modified subpopulation of cells. Selection is then accomplished by exerting a positive selective stimulus on the engineered cells rather than a negative pressure on nonengineered cells.
Type:
Grant
Filed:
January 7, 1999
Date of Patent:
July 13, 2010
Assignees:
Stanford University, University of Washington