Abstract: Methods for synthesizing nanowires are provided. Modified PilA peptides are used as peptide building blocks for synthesizing the nanowires. The method places the peptide building blocks in an assembly buffer with a hydrophobe. Addition of a hydrophobe and molecular crowding by evaporation of the assembly buffer triggers the self-assembly of the peptide building blocks into fibers. Multiple elongation cycles of addition of peptide building blocks, mixing and evaporation are conducted to promote elongation of the fibers and synthesis of nanowires. Electronic characterization of the synthesized nanowires is provided.

Abstract: The present disclosure relates to disaccharides with defined sulfation patterns, and oligosaccharide mimetics comprising the disaccharides as repeating units linked in a head to tail fashion. The present disclosure further relates to methods of making the same, and to methods of using the same to mediate cell proliferation, cell differentiation, amyloid plaque formation, anti-coagulation, and neuronal growth.

Abstract: A method and system for fingerprint recognition includes generating a first set of feature embeddings for a first image at a feature extractor, generating a second set of feature embeddings for a second image at the feature extractor, generating a third set of embeddings at a first classification head from the first set of feature embeddings, generating a fourth set of embeddings at a second classification head from the first set of feature embeddings, generating a fifth set of embeddings at the first classification head from the second, set of feature embeddings, generating a sixth set of embeddings at the second classification head from the second set of feature embeddings, generating a first similarity score based on the third and fourth sets of embeddings and the fifth and sixth set of embeddings and generating a similarity indicator based on the first similarity score.

Abstract: Provided herein is a cell macroencapsulation device composed of hydrogel in a 3D conformation that optimizes encapsulated cell viability and function when transplanted into a vascularized tissue space. The hydrogel macroencapsulation device is intended to reduce or eliminate immune response to the cell graft, while allowing exchange of encapsulated cell-secreted products, such as insulin. Also described herein is an injection-mold and fabrication process to generate the hydrogel macroencapsulation devices for use in the clinic.

Abstract: Tetrazine non-canonical amino acids, methods for making the tetrazine non-canonical amino acids, methods for incorporating the tetrazine non-canonical amino acids into proteins and polypeptides, post-translationally modified proteins and polypeptides in which the tetrazine non-canonical amino acids have been incorporated, and kits for incorporating the tetrazine non-canonical amino acids into proteins and polypeptides.

Abstract: The present disclosure relates generally to compositions and methods for treating inflammatory disorders or mitochondria-associated disorders by activation of Mitochondrial Nuclear Retrograde, Regulator 1 (MNRR1 or CHCHD2).

Abstract: Disclosed herein are compositions comprising a polymer and a metabolic inhibitor, as well as a method of using the composition to modulate an immune response. The composition may be produced in the form of a synthetic tissue for provision in a subject. The composition or synthetic tissue may further comprise additional therapeutic agents.

Abstract: The present invention includes recombinant AAV vectors comprising an inducible transcriptional activator which is operably linked to a muscle-specific promoter, wherein the AAV vector further comprises a capsid gene specific for muscle tissue. The invention further includes methods of producing and using said recombinant AAV vectors to introduce transgenes into target cells and treat diseases in subjects in need thereof.

Abstract: Disclosed are methods of treating malaria with tetrahydrobenzonaphtyridine carboxanilide (TBN) derivatives and related pyrrolinones and hydrolysis products thereof. These compounds are active against Plasmodium falciparum strains that are resistant to multiple drugs currently on the market. The present invention further relates to novel compounds and pharmaceutical compositions comprising such compounds.

Abstract: Methods for inducing growth inhibition or apoptosis of Bcl-2-expressing cells and treatments of Bcl-2 expressing cancers are provided. Additionally, assays for agents that can induce apoptosis of Bcl-2 expressing cells are disclosed.

Abstract: Various examples of a variable stiffness magnetic spring with a linear stroke length are provided. The stiffness of the magnetic springs is varied through rotation of one or more magnets, and both positive and negative spring constants are achievable. In one example, a variable stiffness magnetic spring includes a first magnetic component and a second magnetic component, wherein the first magnetic component is coaxial with the second magnetic component, the first magnetic component is rotatable about an axis and relative to the second magnetic component to adjust a stiffness of the variable stiffness magnetic spring, and the second magnetic component is translatable along the axis and relative to the first magnetic component. While such variable stiffness magnetic springs exhibit highly linear stroke lengths, such variable stiffness magnetic springs can be positioned in series to achieve an even longer linear stroke length.

Abstract: The embodiments of the present invention are directed to a novel wireless powered method, apparatus and tracking system without a wired interface to a moving catheter. The implant in the patient's body on the moving catheter is energized by an external ultrasound transmitter using acoustic pressure waves. As a general mode of operation, ultrasonic waves from outside of a patient's body are received by an array of transducer elements configured about the catheter disposed in a patient's body, wherein the array of transducer elements transforms a frequency into a resultant stored energy. The resultant stored energy powers one or more transceivers via a power management arrangement and enables RF frequencies in a desired band to be output and received by external sensors. Coupled with ultrasound backscattering capabilities, the catheter provides a dual mode for accurate triangulated locations of the distal end of a moving catheter.

Abstract: An efficient and green method for selective extraction of Li from end-of-life secondary LIBs of any capacity and size is provided. Electrochemical driven selective lithium deposition is targeted at the anode/separator interface of the end-of-life LIB. The deposited Li is recovered by processing of an opened or dismantled battery using only distilled or de-ionized water. The process not only enables the recovery of the plated lithium at the anode/separator interface, but also extracts the lithium from the organic salts and/or inorganic salts in the solid electrolyte interface (SEI) layers and from the electrolyte in the separator. In addition, the method partially strips the cyclable Li from the cathode and concentrates it at the anode/separator interface. The concentrated Li is extracted by using aqueous solution such as distilled or de-ionized water followed by recovery of the Li from aqueous solution. After Li recovery from the anode, the method can also enable the recovery of battery-grade graphite.

Abstract: A mosquito control net includes an occupant chamber and a trap chamber disposed over the occupant chamber. The trap chamber has one or more openings disposed on an outer surface thereof, through which mosquitos enter the trap chamber, the openings having receptacles attached therein and extending within the trap chamber to inhibit egression of mosquitos from the trap chamber after entry. A method for preventing mosquito bites for a subject can include providing such a mosquito control net and having the subject occupy it. A kit of parts for converting a conventional mosquito control net into a trapping mosquito control net can comprise a funnel-shaped receptacle surrounded by a bag, the bag being substantially impermeable to mosquitos and the receptacle and/or the bag being attachable to a top surface of the conventional mosquito control net to form a trap compartment.

Abstract: Disclosed are compounds having a monoterpenoid and/or phenylpropanoid moiety and methods of their making and use as pesticidal compounds, such as insecticidal baits.

Abstract: A heterogeneous energy storage device and a method for controlling a heterogeneous energy storage device are provided. In one implementation, a heterogeneous energy storage device is provided. The heterogeneous energy storage device includes a first energy storage device, a second energy storage device and a capacitive device. The first energy storage device has a first energy capacity and a first power to energy ratio (P/E). The second energy storage device has a second total energy capacity and a second P/E ratio different from the first P/E ratio. The capacitive device is coupled in series with the first energy storage device, wherein the second energy storage device is coupled in parallel with the series combination of the capacitive device and the first energy storage device. In another implementation, a method of controlling a heterogeneous energy storage device including a first energy storage device and a second energy storage device is provided.

Abstract: The current disclosure provides methods for detecting and analyzing K17 expression in a bladder sample obtained from a subject. The current disclosure also pertains to methods and kits for identifying a mammalian subject with bladder cancer by detecting the expression of K17 in a sample. The present methods include both cell-based and cell-free methods for determining the level of keratin 17 in a sample obtained from the bladder of a subject.

Abstract: In accordance with the purpose(s) of the present disclosure, as embodied and broadly described herein, the disclosure, in one aspect, relates to solid chalcohalide electrolytes and the efficient synthesis of solid chalcohalide electrolytes. The electrolytes have the general formula AaMbNcXdYeSf and have relatively high ionic conductivity. The electrolytes can be a component of different types of batteries. The process of synthesizing the electrolytes can be done with cost-effective materials, which is useful for scaling-up production of batteries such as all-solid-state batteries.

Abstract: The rice cultivar designated ‘Addi Jo’ and its hybrids and derivatives are disclosed.

Abstract: A device and method for early detection of eye disease including a corneal topography device including a camera, such as a rotating Scheimpflug camera, configured to measure the elevation of a patient's two anterior corneas sequentially or simultaneously; a computer processor; and non-transitory computer readable media including computer readable instructions, which, when executed by the computer processor, causes the device to measure and store elevation data at a plurality of points on the patient's anterior corneal surfaces; organize the elevation data for each cornea into a two-dimensional matrix where the center of the cornea is in the center of the data frame, rotate the data for a first eye 180 degrees around the Y axis relative to a second eye, subtract data on each corresponding corneal point, and generate an elevation difference matrix showing the degree of symmetry or asymmetry between the patient's left and right eye corneal topography.