Abstract: A system and method utilizes optical depth sensors to estimate heart rate of one or more subjects. A method includes obtaining optical depth video data of at least one subject; identifying a region of interest of the subject(s) from optical depth video data; segmenting the region of interest into multiple areas; identifying pixel intensity with respect to time in the areas to produce a depth signal data matrix including multiple spatial channels; decomposing the depth signal data matrix into a low-rank spatial-temporal eigenvector matrix to produce refined depth signal data streams; and projecting the refined depth signal data streams onto a selected pulsatile direction and producing a cardiac pulse signal for the subject(s).

Abstract: A material for separating and pumping oxygen is disclosed. The material is a zeolite doped with a chemical element having an electron density of between 30 kJ/mol and 150 kJ/mol. The material is configured for controllable oxygen desorption between 150° C. and 300° C. and pumping the released oxygen into an area having an ambient pressure of less than 100 pascals.

Abstract: Various embodiments of a magneto-acoustic spin-wave signal processing system are provided. In one embodiment, a system includes an acoustic wave transducer configured to produce surface acoustic waves in a plane of a magnetostrictive material, wherein the magnetostrictive material serves as a medium for spin waves traveling in the plane, and wherein the acoustic wave transducer is oriented such that the acoustic waves parametrically amplify the spin waves. In this way, signal processing systems achieve the benefits of both spin wave and acoustic wave devices, taking advantage of the low dispersion and high dynamic range of acoustic waves coupled with the tunability and nonlinear effects provided by spin waves.

Abstract: Wearable fetal health monitoring device for determining a heath condition of a fetus based on biosignals of an expecting mother and the fetus is provided. The device includes a MEMS accelerometer that converts an acoustic wave sensed in an abdominal region into an abdominal acoustic signal. The device also includes a pulse oximeter generates a maternal photoplethysmogram (mPPG) value from a pulse sensed in the abdominal region. The device further includes a microcontroller configured to: generate a maternal phonocardiogram (mPCG) value from the abdominal acoustic signal; calculate a first maternal heart rate (mHR) value from the mPCG value; calculate a second mHR value from the mPPG value; compare the first mHR value with the second mHR value to identify a noise correction value; and apply the identified noise correction value to the mPCG value to extract a fetal phonocardiogram (fPCG) value.

Abstract: A system and method for clock distribution in a digital circuit. In some embodiments, the method, includes: modifying a synchronous digital logic circuit, the modifying including: replacing a first D flipflop in the circuit with a local-clocking source flipflop; and connecting a clock output of the local-clocking source flipflop to a clock input of a second D flipflop, wherein the replacing and connecting increases an objective function, the objective function being based on the number of high drive strength cells in a logic cone preceding the second D flipflop.

Abstract: The present disclosure describes electron-photon and electron-phonon interactions in 2D material systems. In some embodiments, novel entangled states are implemented. Such entangled states may involve the superposition of electronic and phononic modes in these materials. The states may be utilized to realize the transduction of quantum information and sensing. In an aspect, the present disclosure may be a quantum sensor having a single-phonon emitter configured to emit a single phonon. A phononic transducer is configured to receive the emitted single phonon from the single-phonon emitter and propagate the single phonon. A phonon detector is configured to detect an arrival of the propagated single phonon received from the phononic transducer.

Abstract: For tracking a target, method detects, by use of a processor, that the target is present. The method estimates an initial target position. The method further tracks the target position from channel state information Doppler frequency measurements using at least one of an extended Kalman filter, a Viterbi algorithm, and a particle filter.

Abstract: The present invention provides in certain embodiments comprising a pyrrolysine-based aminoacyl-tRNA synthetase and a tRNA to form a pyrrolysine-based aminoacyl-tRNA synthetase/tRNA pair. The present invention also provides novel pyrrolysine-based aminoacyl-tRNA synthetases, cells and compositions comprising pyrrolysine-based aminoacyl-tRNA synthetases. The present invention also provides methods of using these pyrrolysine-based aminoacyl-tRNA synthetases.

Abstract: A method for training an artificial intelligence (AI) model includes receiving a training dataset and utilizing processing circuitry to train a Bayesian Neural Network (BNN) based on the dataset and a selected training algorithm including backpropagation. The method estimates aleatoric and epistemic uncertainty for each sample in the dataset. Based on these uncertainty estimates, weights are assigned to the samples, prioritizing those with lower aleatoric uncertainty. A conditioned training dataset is generated by increasing the weights of these prioritized samples. The AI model is then trained using this conditioned dataset. Finally, the pre-trained AI model outputs a prediction. This approach improves model performance by focusing on data with more predictable characteristics, reducing bias and enhancing prediction reliability.

Abstract: Disclosed is a platform for fluorescence imaging of bulk RNA dynamics in living cells. The platform utilizes a technique including exposing a plurality of live cells configured to overexpress a WT or mutant ribonucleoside kinase UCK2 under control of an inducible promoter, a constitutively active promoter, or both, to a first quantity of a fluorescent nucleoside (such as fluorescent bicyclic and tricyclic cytidine analogues) for a first period of time.

Abstract: A magnetic release assembly includes a housing defining a cavity, a permanent electromagnet positioned within the cavity, and a microcontroller electronically coupled with the permanent electromagnet. The microcontroller is configured to selectively provide power to the permanent electromagnet. A timer board is in communication with the microcontroller. A power source is electronically coupled with the microcontroller, the permanent electromagnet, and the timer board. The microcontroller is configured to provide power to the permanent electromagnet in response to an alarm from the timer board.

Abstract: 3,4-thiazolo steroids are provided herein. Also provided herein are methods of making and using the same for the inhibition of cell proliferation or the killing of cells.

Abstract: A substrate having an antibacterial surface includes a chitosan matrix and water-stable metal-organic frameworks dispersed throughout the chitosan matrix. The water-stable metal-organic frameworks are present in an amount of 5% wt/wt to 20% wt/wt based on total solids of the substrate.

Abstract: A method for treating a bone defect extending between a proximal bone structure and a distal bone structure of a patient may include resecting a region of bone between the proximal bone structure and the distal bone structure and encompassing the bone defect, positioning a biodegradable osteogenic scaffold within a biodegradable sleeve, coupling the biodegradable sleeve to a fixation member, positioning the biodegradable sleeve between the proximal bone structure and the distal bone structure, and attaching the fixation member to each of the proximal bone structure and the distal bone structure.

Abstract: Methods of treating disease include measuring a CCR2 profile of a patent, selecting a CCR2 antagonist based on the CCR2 profile of the patient, and administering the CCR2 antagonist to the patient. Methods for stratifying one or more patients for pain medication based on a CCR2 profile include measuring a CCR2 profile of one or more patients and partitioning the one or more patients into predetermined groups or subgroups based on the CCR2 profile of the one or more patients. Kits for performing the methods are also described.

Abstract: The present disclosure provides nucleic acid compositions that incorporate one or more halouracil molecules. More specifically, the present disclosure reveals that the replacement of uracil nucleotides within a microRNA nucleotide sequence with a 5-halouracil increases the ability of the micro-RNA to inhibit cancer progression and tumorigenesis. As such, the present disclosure provides various nucleic acid (e.g., microRNA) compositions having 5-halouracil molecules incorporated in their nucleic acid sequences and methods for using the same. The present disclosure further provides pharmaceutical compositions comprising the modified nucleic acid compositions, and methods for treating cancers using the same.

Abstract: Various embodiments of a vision-guided unmanned aerial vehicle (UAV) system to identify and collect foreign objects from the surface of a body of water are disclosed herein. A vision system and methodology has been developed to reduce reflections and glare from a water surface to better identify an object for removal. A linearized polarization filter and a specularity-removal algorithm is used to eliminate excessive reflection and glare. A contour-based detection algorithm is implemented for detecting the targeted objects on water surface. Further, the system includes a boundary layer sliding mode control (BLSMC) methodology to reduce and minimize position and velocity errors between the UAV and object in the presence of modeling and parameter uncertainties due to variation in a moving water surface.

Abstract: Described herein are means for generating pre-trained models for nnU-Net through the use of improved transfer learning techniques, in which the pre-trained models are then utilized for the processing of medical imaging.

Abstract: Oral compositions and methods of use thereof are provided herein. The oral compositions comprise a first component comprising at least one Eh-raising compound and a pharmaceutically acceptable carrier, and a second component comprising at least one zinc compound, an anti-microbial agent and a pharmaceutically acceptable carrier.

Abstract: A new variety of sweetpotato, identified as ‘LA18-100,’ is disclosed having resistance to both southern root-knot nematode and Streptomyces soil rot; an orange-fleshed storage root, copper to light rose skin, early crops, and high yields.