Abstract: Devices and methods for photoacoustic tomography are disclosed herein. One exemplary photoacoustic tomography device uses a laser to produce acoustic waves in a sample. A transducer receives the acoustic waves through a slit formed by one or more blades positioned substantially parallel to the receiving aperture of the transducer. An acoustic absorber is affixed to each of the one or more blades along a surface proximal to the transducer. A processor acquires acoustic data and reconstructs photoacoustic tomographic images based on the acquired data. Reconstructing the image involves setting reconstruction parameters, defining a reconstruction area, reconstruction position, and pixel size, and calculating an acoustic travelling path for the sample to each transducer element. The acoustic travelling paths are saved into a three-dimensional array.
Type:
Grant
Filed:
December 5, 2016
Date of Patent:
March 8, 2022
Assignee:
The Research Foundation for The State University of New York
Abstract: Described herein are vectors, such as adeno-associated virus (AAV) vectors, and recombinant AAV expressing Smad7. The disclosed AAV vectors and rAAV can be used for therapeutic applications in the treatment and amelioration of muscle wasting, cardiac and/or skeletal muscle wasting associated with cancer cachexia.
Type:
Grant
Filed:
April 22, 2016
Date of Patent:
March 8, 2022
Assignees:
Washington State University, Baker Heart and Diabetes Institute
Abstract: Methods, compositions, devices, and kits are described herein that are useful for detecting BoHV-1 infection in animals and/or for distinguishing animals that may benefit from administration of BoHV-1 tmv vaccine.
Type:
Grant
Filed:
June 9, 2020
Date of Patent:
March 8, 2022
Assignee:
Board of Supervisors of Louisiana State University and Agricultural and Mechanical College
Abstract: Described herein are redox active materials based on functionalization of 2,5-di(pyridine-4-yl)thiazolo-[5,4-d]thiazole (Py2TTz). Also described herein are aqueous organic redox flow batteries that include a first redox active material and a second redox active material comprising a viologen compound or a salt thereof.
Abstract: Various embodiments of an intersection management system for managing autonomous vehicles approaching an intersection in which a Time of Arrival, Velocity of Arrival, and path trajectory are calculated for each approaching vehicle are disclosed.
Type:
Grant
Filed:
November 25, 2019
Date of Patent:
March 8, 2022
Assignee:
Arizona Board of Regents on Behalf of Arizona State University
Inventors:
Mohammad Khayatian, Aviral Shrivastava, Mohammadreza Mehrabian
Abstract: The present invention provides a method of inhibiting, suppressing or preventing levodopa-induced dyskinesia in a patient suffering from Parkinson's Disease, comprising the step of administering to the patient a pharmaceutical composition comprising at least one compound of the invention. The present invention further provides a method of inhibiting, suppressing or preventing Parkinson's Disease in a patient, comprising the step of administering to the patient a pharmaceutical composition comprising at least one compound of the invention.
Type:
Grant
Filed:
January 24, 2020
Date of Patent:
March 8, 2022
Assignees:
Drexel University, Rutgers, The State University of New Jersey
Inventors:
Sandhya Kortagere, Eldo V. Kuzhikandahil
Abstract: Methods for treating diseases and conditions mediated by the high affinity IgE receptor (Fc?RI). Antisense oligomers for modulating splicing of mRNA encoding the Fc?RI? protein, thereby down-regulating cell-surface expression of Fc?RI, and uses of the antisense oligomers for inhibiting mast cell degranulation, cytokine release, migration, and proliferation.
Type:
Grant
Filed:
August 1, 2018
Date of Patent:
March 8, 2022
Assignees:
North Carolina State University, The United States of America, as represented by the Secretary, Department of Health and Human Services
Abstract: Methods, systems, and devices for wireless communications are described. An example method for object detection is provided which may include capturing at least three polarization angles of a scene. The method may include translating polarization parameters associated with the at least three polarization angles to a reference angle to create a vector map and resolving the vector map into parallel components and perpendicular components, wherein the parallel components are parallel to a plane of incidence of light in the scene and the perpendicular components are perpendicular. The method may further include determining a range map based at least in part on the parallel and perpendicular components, detecting an object present in the scene using the range map and an airlight scattering polarization component, and outputting an indication of the object.
Type:
Application
Filed:
September 1, 2020
Publication date:
March 3, 2022
Applicant:
Utah State University Space Dynamics Laboratory
Abstract: The present invention relates to novel primers and sloppy molecular beacon and molecular beacon probes for amplifying segments from different genes in Mycobacterium tuberculosis for identifying the presence of M.tb DNA and/or resistance to anti-tuberculosis drugs.
Type:
Application
Filed:
November 16, 2021
Publication date:
March 3, 2022
Applicant:
Rutgers, The State University of New Jersey
Abstract: Adaptive and hierarchical convolutional neural networks (AH-CNNs) using partial reconfiguration on a field-programmable gate array (FPGA) are provided. An AH-CNN is implemented to adaptively switch between shallow and deep networks to reach a higher throughput on resource-constrained devices, such as a multiprocessor system on a chip (MPSoC) with a central processing unit (CPU) and FPGA. To this end, the AH-CNN includes a novel CNN architecture having three parts: 1) a shallow part which is a light-weight CNN model, 2) a decision layer which evaluates the shallow part's performance and makes a decision whether deeper processing would be beneficial, and 3) one or more deep parts which are deep CNNs with a high inference accuracy.
Type:
Application
Filed:
September 1, 2021
Publication date:
March 3, 2022
Applicant:
Arizona Board of Regents on behalf of Arizona State University
Abstract: A flexible sensor is provided. A further aspect employs a sensor apparatus including pressure or force sensing layers or sheets in addition to location sensing layers or sheets. In another aspect, an electrical sensing circuit and flexible films are used to sense pressure and/or location of a contacting object. In another aspect, a compressible polymer includes conductive particles therein such that the compressible polymer changes electrical resistance when compressed to indicate a force or location. Still another aspect has stacked sandwiches of pressure and/or location sensing films, layers or sheets.
Type:
Application
Filed:
August 28, 2020
Publication date:
March 3, 2022
Applicant:
Board of Trustees of Michigan State University
Abstract: The present disclosure relates to triblock and pentablock copolymers and methods of making thereof. Aspects of the disclosure further relate to block copolymer hydrogels that exhibit both fatigue resistance and fracture resistance with superior rates of recovery.
Type:
Application
Filed:
August 25, 2021
Publication date:
March 3, 2022
Applicant:
Colorado State University Research Foundation
Abstract: Kits and methods to distinguish between false and true labor are provided. The kits and methods can utilize differences in abundance and/or differences in the rate of change in abundance of B7-H2, SORC2, TF, C1-Esterase Inhibitor, Ran, IMDH1 and/or PGAM1, as markers of true labor.
Type:
Application
Filed:
November 12, 2021
Publication date:
March 3, 2022
Applicants:
Wayne State University, The United States of America, as Represented by the Secretary, Department of Health & Human Service
Inventors:
Adi L. Tarca, Piya Chaemsaithong, Tinnakorn Chaiworapongsa, Sonia S. Hassan, Roberto Romero
Abstract: Methods for determining lipid composition. The lipid(s) in a composition may include phospholipids. A method may be carried out on an individual cell. A method may compare the Raman spectrum of the portion of a cell with a model Raman spectrum, which does not include the lipid component, where the difference between the Raman spectrum of the portion of the cell and the model Raman spectrum correlates to the lipid composition in the portion of the cell in the portion of the cell). A method may be used to diagnose a disease such as, for example, cancers, including breast cancer, prostate cancer, and via the presence and/or absence of abnormal or damaged cells in an individual.
Type:
Grant
Filed:
July 11, 2019
Date of Patent:
March 1, 2022
Assignees:
Advanced Cytometry Instrumentation Systems, LLC, The Research Foundation for The State University of New York
Inventors:
Andrey N. Kuzmin, Artem Pliss, Paras N. Prasad
Abstract: The present invention pertains to methods of determining where, on the skin, a diagnostic, therapeutic, or cosmetic agent is likely to be most effectively applied (e.g., injected), and to methods for monitoring a patient after such an agent has been administered. The monitoring can produce information useful in determining whether a diagnostic, therapeutic (e.g., surgical), or cosmetic regime should be initiated, continued, continued in a modified fashion, or terminated (e.g., for a brief or prolonged period of time). The methods can be repeated periodically and use a non-invasive, in vivo form of digital image speckle correlation (DISC) to track deformation of the skin.
Type:
Grant
Filed:
April 3, 2018
Date of Patent:
March 1, 2022
Assignee:
The Research Foundation for State University of New York
Inventors:
Divya Bhatnagar, Miriam Rafailovich, Raphael Davis, Alexander B. Dagum, Duc T. Bui
Abstract: Coated nanowires comprising a core and a ferromagnetic coating are magnetically aligned and bound to a substrate. The substrate may have a thiol-functionalized surface. In some examples, the coated nanowires are nickel-coated copper nanowires and the substrate may be a carbon-doped oxide or silicon oxide.
Type:
Grant
Filed:
October 14, 2019
Date of Patent:
March 1, 2022
Assignee:
Portland State University
Inventors:
Shankar B. Rananavare, Srikar Rao Darmakkolla
Abstract: The present invention provides plant virus vectors developed from the Sugarcane mosaic virus (SCMV). The vectors include a nucleic acid sequence encoding an infectious Sugarcane mosaic virus (SCMV) operably linked to one or more regulatory elements functional in a plant. The plant virus vectors may be used to infect monocot plants, such as maize, for gene expression applications.
Type:
Grant
Filed:
May 18, 2020
Date of Patent:
March 1, 2022
Assignee:
Iowa State University Research Foundation, Inc.
Inventors:
John Hemmingson Hill, Steven Alan Whitham, Yu Mei, Chunquan Zhang
Abstract: Provided are macrocyclic compounds and compounds with two or more macrocyclic groups, iron coordinated macrocyclic compounds, and iron coordinated compounds with two or more macrocyclic groups. The iron is high-spin iron(III). The iron coordinated compounds may exhibit a negative redox potential (e.g., relative to a normal hydrogen electrode at a biologically relevant pH, for example, a pH of 6.5-7.5). The compounds can be used as MRI contrast agents.
Type:
Grant
Filed:
May 21, 2018
Date of Patent:
March 1, 2022
Assignee:
The Research Foundation for The State University of New York
Inventors:
Janet R. Morrow, Eric M. Snyder, Didar Asik