Abstract: A method includes receiving multiple compound muscle action potential values (CMAPs), wherein each CMAP is an onset latency, a peak latency, a conduction velocity, or a response amplitude measured from a baseline; for each of the CMAPs and for each of a number parameters calculated from the CMAPs, determining a corresponding demyelinating boundary value using a normal value from a preselected population; determining whether each of the CMAPs and each of the parameters exceeds the corresponding demyelinating boundary value; determining one or more demyelinated nerve pathways based on which of the CMAPs and the parameters exceeds the corresponding demyelinating boundary value; indicating on a display which of the CMAPs and the parameters exceed the corresponding demyelinating boundary value; and displaying, in pictorial form, an anatomical diagram indicating the demyelinated nerve pathways.
Type:
Grant
Filed:
November 4, 2014
Date of Patent:
December 3, 2019
Assignee:
The Research Foundation of State University of New York
Inventors:
Paul Jacob Maccabee, Lawrence Philip Eberle
Abstract: The invention relates to a method for photoreleasing a moiety G from a compound of the formula A-G. The methods of the present invention comprise irradiating a composition comprising the compound of the formula A-G at a wavelength of >500 nm, so as to photorelease the moiety G from the moiety A; wherein the moiety A comprises a chromophore and the moiety G comprises an organic compound.
Type:
Grant
Filed:
September 24, 2018
Date of Patent:
December 3, 2019
Assignee:
Iowa State University Research Foundation, Inc.
Abstract: The present invention relates to a method for detecting renal disease and for assessing the efficacy of dialysis treatment using imaging agents having desirable in vivo properties.
Type:
Grant
Filed:
June 26, 2017
Date of Patent:
December 3, 2019
Assignees:
Beth Israel Deaconess Medical Center, Georgia State University Research Foundation Inc.
Abstract: A new solvent-based method is presented for making low-cost composite graphite electrodes containing a thermoplastic binder. The electrodes, termed thermoplastic electrodes (TPEs), are easy to fabricate and pattern, give excellent electrochemical performance, and have high conductivity (1500 S m?1). The thermoplastic binder enables the electrodes to be hot embossed, molded, templated, and/or cut with a CO2 laser into a variety of intricate patterns. These electrodes show a marked improvement in peak current, peak separation, and resistance to charge transfer over traditional carbon electrodes. The impact of electrode composition, surface treatment (sanding, polishing, plasma treatment), and graphite source were found to impact fabrication, patterning, conductivity, and electrochemical performance. Under optimized conditions, electrodes generated responses similar to more expensive and difficult to fabricate graphene and highly oriented pyrolytic graphite electrodes.
Type:
Application
Filed:
August 6, 2019
Publication date:
November 28, 2019
Applicant:
Colorado State University Research Foundation
Abstract: This disclosure describes compositions and methods for enhanced production of enduracidin in genetically engineered strains of Streptomycesfungicidicus. In particular, the present disclosure describes the genetic manipulation of regulatory genes orf24 and orf18 associated with the enduracidin (enramycin) biosynthesis gene cluster from Streptomyces fungicidicus to generate vector constructs and recombinant strains producing greater yields of enduracidin.
Abstract: A liquid crystal display is configured such that a composite layer thereof is transparent to incident light in one voltage condition (e.g., in the absence of an applied voltage) and scatters incident light out of the display in another voltage condition (e.g., when a voltage is applied). The liquid crystal display does not need polarizers or color filters.
Type:
Application
Filed:
September 11, 2017
Publication date:
November 28, 2019
Applicants:
Kent State University, BOE Technology Group Co., Ltd.
Abstract: The present disclosure relates to wheat plants having grain with high ?-glucan content, methods for constructing said wheat plants, grain therefrom and uses thereof. Wheat lines homozygous for the HvCslF6 gene from barley having five times the fiber content and an increased ?-glucan content of TA5790, TA5792, and TA5795 are disclosed.
Type:
Application
Filed:
August 7, 2019
Publication date:
November 28, 2019
Applicants:
General Mills, Inc., Kansas State University Research Foundation
Inventors:
Jesse Poland, Bernd Friebe, Titiana Danilova, Bikram S. Gill, Eric Jackson
Abstract: A bistable cholesteric liquid crystal switchable window has two stable states in the absence of an applied voltage. A first stable state is a planar state which is transparent or reflective for visible light. A second stable state is a focal conic state which is opaque for visible light. The window can be switched from the first stable state to the second stable state via a first voltage pulse and from the second stable state to the first stable state via a second voltage pulse. The first voltage pulse and the second voltage pulse may have the same frequency.
Abstract: The invention provides a metallopolymer coordination network comprising one or more coinage or similar metals and a glyme or glyme-equivalent. The composition has an amorphous polymer network that is significantly stronger than previously reported supramolecular hydrogels synthesized without glyme. Glyme chain length and water content strongly influence the mechanical, electronic, and optical behavior of the network.
Type:
Grant
Filed:
December 2, 2016
Date of Patent:
November 26, 2019
Assignee:
Colorado State University Research Foundation
Inventors:
William Scott Compel, Christopher J. Ackerson, O. Andrea Wong
Abstract: The present disclosure provides intramedullary mandibular implants for the temporomandibular joint. The mandibular implants include a stem portion, a collar portion and a head portion. The stem, collar and head portions may be integral. The stem portion may define an inferior end and the head portion may define a superior end of the implants. The head portion may be arcuate in the sagittal plane to provide an articulating surface with a fossa or a fossa component. The collar portion may be intermediate of the head and stem portions and form a channel between an interior surface of the collar portion and an exterior surface of the stem portion. In use, the stem portion may be implanted within a condyle of a mandible such that an end portion of the condyle is situated within the channel of the implant and the head portion articulates with the fossa or fossa component.
Type:
Grant
Filed:
December 22, 2016
Date of Patent:
November 26, 2019
Assignee:
The Research Foundation for the State University of New York
Inventors:
Martin Pendola, Gaia Salvadore, Rehan Khan
Abstract: This invention relates to the field of polymers and olefin polymerization, and more specifically olefin metathesis polymerization. Specifically, the present invention provides a polymer comprising rigorously alternating AB subunits and methods of formation of the AB alternating polymers. In the polymers and process of the invention, the A monomer is derived from a cyclobutene derivative, and the B monomer is derived from a cyclohexene derivative. The polymerization takes place in the presence of an olefin metathesis catalyst.
Type:
Grant
Filed:
March 21, 2016
Date of Patent:
November 26, 2019
Assignee:
The Research Foundation for The State University of New York
Inventors:
Nicole S. Sampson, Li Tan, Kathlyn Parker
Abstract: Compositions and methods for preparing and using ceramic mixed ionic-electronic conductor (MIEC) enhanced transition metals and metal oxides in composite or core-shell forms are disclosed. The presently disclosed compositions are stable at high temperatures and can carry as much as about 20 weight % oxygen.
Abstract: Systems and methods for determining a Material's (“MTL”) mechanical properties. The methods comprise: coupling a first end of MTL to a First Mechanical Mechanism (“FMM”) movable in a First Direction (“FD”) and coupling a second end of MTL to a Second Mechanical Mechanism (“SMM”) movable in a Second Direction (“SD”); applying a first Pulling Force (“PF”) to MTL; applying an Oscillating Force (“OF”) to MTL; applying a second PF to MTL so as to cause any undulations in MTL to be removed and to cause a loading of fibers or polymeric units that support MTL; allowing MTL to oscillate through a series of cycles of loading and unloading; measuring a strain/stress on MTL as a function of time; determining a natural frequency of MTL based on the strain/stress; and determining an elastic modulus of MTL using the natural frequency.
Type:
Grant
Filed:
October 12, 2016
Date of Patent:
November 26, 2019
Assignee:
Rutgers, The State University of New Jersey
Inventors:
Frederick H. Silver, Dmitry Khavulya, Mark Pierce
Abstract: A sampling device is constructed having an airflow path from a size-selective inlet to a device outlet, without using any tubing. The size-selective inlet includes at least one of an impactor, a filter, a cyclone, and an inhalable inlet. The device includes a sampling assembly configured to be removably coupled directly to a sampling device housing (e.g., without using tubing), and an airflow assembly that may be constructed without using tubing.
Type:
Grant
Filed:
February 25, 2017
Date of Patent:
November 26, 2019
Assignee:
Colorado State University Research Foundation
Inventors:
Daniel D. Miller-Lionberg, Casey William Quinn, John Volckens, David Leith
Abstract: An apparatus and method for measuring small changes in the centroid of the spectrum of a light field by conversion of optical frequency centroid shifts into time delays are described. A time delay for a particular frequency of light is created by directing the light into an optically dispersive system that converts the change in center frequency to a change in transit time through the system as the dispersive element causes different colors to travel at different speeds. Examples of such dispersive elements include, but are not limited to, optical fibers, bulk materials, volumetric or fiber Bragg gratings, and grating or prism based pulse stretchers. This time delay can be measured, by detecting the change in transit time (or time of flight through the dispersive element) by using a detector such as a photodiode, PMT, etc. that converts the incident optical pulse train into an electronic pulsed signal.
Type:
Grant
Filed:
June 10, 2015
Date of Patent:
November 26, 2019
Assignee:
Colorado State University Research Foundation
Abstract: Inorganic plastic crystal electrolytes, also referred to herein as inorganic plastic crystal conductors or single ion conductors including [ABx-yCy]y?[M]y+, where A is a tetravalent to hexavalent atom; B is a monovalent ligand; C is an oxyanion; M is an alkali metal; x is 4 when A is tetravalent, x is 5 when A is pentavalent, and x is 6 when A is hexavalent; y is an integer from 1 to x?1 inclusive. [ABx-yCy]y?[M]y+ is rotationally disordered and ionically conductive.
Type:
Grant
Filed:
March 14, 2014
Date of Patent:
November 26, 2019
Assignee:
Arizona Board of Regents, a Body Corporate of the State of Arizona Acting for and on Behalf of Arizona State University
Inventors:
C. Austen Angell, Iolanda Santana Klein, Telpriore Greg Tucker
Abstract: This disclosure describes a novel PRACH scheme based on an Analog Bloom Filter, in which user equipment is allowed to transmit multiple sequences to a base station, instead of only one sequence as is the case with the current LTE. A new decoding algorithm is disclosed, which copes with the unique challenges in the signal generated with ZC sequences, such as peak shifting and multiple peaks. In addition, when CFO can be removed the new scheme allows the UE to piggyback log 2 7 bits of information along with the signal. Evaluation shows that the new scheme outperforms the existing PRACH of LTE by more than an order of magnitude in many cases, and therefore is a good candidate as the PRACH for future wireless networks (e.g., 5G).
Type:
Application
Filed:
May 15, 2019
Publication date:
November 21, 2019
Applicant:
The Florida State University Research Foundation, Inc.
Abstract: The present disclosure provides for isolated non-naturally occurring, mutant-human IAPP polypeptides, which are more soluble at neutral pH than the wild-type hIAPP protein. These polypeptides can be formulated or co-formulated at physiological pH, which enable the polypeptides of the instant disclosure to be delivered to a subject in a single injection with an insulin agent. The present disclosure also provides methods and pharmacological compositions for treating an abnormal condition, such as an amyloid-based disease or type-1 diabetes in a subject.
Type:
Application
Filed:
February 1, 2018
Publication date:
November 21, 2019
Applicant:
The Research Foundation for The State University of New York
Inventors:
Daniel RALEIGH, Rehana AKTER, Andisheh ABEDINI