Abstract: The disclosure provides helix grafted proteins, methods of producing helix grafted proteins and methods of use of helix grafted proteins as inhibitors of protein-protein interactions involved in disease pathogenesis.
Type:
Application
Filed:
August 7, 2019
Publication date:
November 21, 2019
Applicant:
Colorado State University Research Foundation
Inventors:
Brian R. McNaughton, Susanne N. Walker, Rachel L. Tennyson, Alan J. Kennan
Abstract: The disclosed technology relates generally to apparatus comprising conductive polymers and more particularly to tag and tag devices comprising a redox-active polymer film, and method of using and manufacturing the same. In one aspect, an apparatus includes a substrate and a conductive structure formed on the substrate which includes a layer of redox-active polymer film having mobile ions and electrons. The conductive structure further includes a first terminal and a second terminal configured to receive an electrical signal therebetween, where the layer of redox-active polymer is configured to conduct an electrical current generated by the mobile ions and the electrons in response to the electrical signal. The apparatus additionally includes a detection circuit operatively coupled to the conductive structure and configured to detect the electrical current flowing through the conductive structure.
Type:
Grant
Filed:
March 12, 2019
Date of Patent:
November 19, 2019
Assignee:
Arizona Board of Regents on Behalf of Arizona State University
Inventors:
Paul B. Johnson, Jose Antonio Bautista-Martinez, Cody A. Friesen, Elise Switzer
Abstract: The present disclosure describes compositions and methods to promote wound healing. The compositions and methods include an interleukin-1 beta (IL-1B) receptor antagonist (IL-1Ra), such as anakinra.
Abstract: The present invention provides novel methods of diagnosing and determining treatment strategies for Lyme disease and other tick-borne illnesses.
Type:
Grant
Filed:
September 10, 2014
Date of Patent:
November 19, 2019
Assignee:
Rutgers, the State University of New Jersey
Abstract: VO2 and V2O5 nano- or micro-materials. The VO2 nano-materials and micro-materials have an M1 phase structure and oxygen stoichiometry that deviates 2% or less from theoretical stoichiometry. The VO2 nano-materials and micro-materials may doped with cation dopants and/or anion dopants. The VO2 and V2O5 nano- or micro-materials can be made by hydrothermal methods starting with V3O7.H2O nano- or micro-material. The VO2 and V2O5 nano- or micro-materials can be used as, for example, thermochromic window coatings.
Type:
Grant
Filed:
August 26, 2015
Date of Patent:
November 19, 2019
Assignee:
The Research Foundation for The State University of New York
Abstract: A novel material for producing auxetic foams is disclosed. The material comprises a multiphase, multicomponent polymer foam with a filler polymer having a carefully selected glass transition temperature. Novel methods for producing auxetic foams from the material are also disclosed that consistently, reliably and quickly produce auxetic polyurethane foam at about room temperature (25° C.). This technology overcomes challenging issues in the large-scale production of auxetic PU foams, such as unfavorable heat-transmission problem and harmful organic solvents.
Type:
Grant
Filed:
January 20, 2017
Date of Patent:
November 19, 2019
Assignee:
The Florida State University Research Foundation, Inc.
Abstract: Compositions containing fungal pigments and methods for making the compositions are described, as are methods of staining, painting or dyeing objects with such compositions.
Type:
Grant
Filed:
September 15, 2016
Date of Patent:
November 19, 2019
Assignee:
Oregon State University
Inventors:
Sara C. Robinson, Sarath Mercedes Vega Gutierrez
Abstract: A method, a computer readable medium and an apparatus for optimizing a cellular network architecture are disclosed. For example, the method obtains network traffic data for a plurality of different endpoint device types, wherein the network traffic data comprises network traffic data for each of the plurality of different endpoint device types, and predicts a future traffic pattern for one of the plurality of different endpoint device types based on the network traffic data. The method then adjusts a parameter of the cellular network architecture in response to the future traffic pattern predicted for the one of the plurality of different endpoint device types.
Type:
Grant
Filed:
June 26, 2017
Date of Patent:
November 19, 2019
Assignees:
AT&T Intellectual Property I, L.P., Board of Trustees of Michigan State University
Inventors:
Jia Wang, Lusheng Ji, Xiang-Yang Alexander Liu, Muhammad Zubair Shafiq
Abstract: Described herein are bacterial microcompartments shell proteins modified to stably incorporate iron-sulfur clusters. Such bacterial microcompartments shell proteins exhibit redox cycling and confer electron transfer functionality to bacterial microcompartment shells.
Type:
Grant
Filed:
December 21, 2017
Date of Patent:
November 19, 2019
Assignee:
Board of Trustees of Michigan State University
Inventors:
Cheryl A. Kerfeld, Clement Aussignargues
Abstract: The present invention relates to compositions for and methods of optically imaging tissues or cells using imaging agents having desirable in vivo properties that result in improved signal-to-background ratio.
Type:
Grant
Filed:
February 23, 2018
Date of Patent:
November 19, 2019
Assignees:
Beth Israel Deaconess Medical Center, Inc., Georgia State University Research Foundation Inc.
Abstract: The present disclosure relates to flexible thermoelectric devices. In some embodiments, such devices can comprise a flexible substrate with a first conductive component and a second, different conductive component deposited thereon so as to form a plurality of electrical junctions. The flexible substrate can be a fabric, and the conductive component can be deposited by methods such as stitching of conductive yarns or deposition of conductive inks. The present disclosure further relates to methods of preparing flexible thermoelectric devices and methods of utilizing flexible thermoelectric devices for producing electrical current from waste heat.
Type:
Grant
Filed:
February 7, 2018
Date of Patent:
November 19, 2019
Assignees:
North Carolina State University, University of Virginia Patent Foundation
Inventors:
Jesse Jur, Mark Losego, Patrick E. Hopkins
Abstract: A method for computing patient-specific hemodynamics. The method includes receiving three dimensional imaging data of a patent, extracting anatomical data from the three dimensional imaging data, calculating velocity and pressure fields corresponding to the extracted anatomical data, and calculating displacement and velocity of extracted solid particles corresponding to the anatomical data. The anatomical data comprises an anatomical boundary.
Type:
Grant
Filed:
October 22, 2015
Date of Patent:
November 19, 2019
Assignees:
Indiana University Research and Technology Corporation, Kent State University
Abstract: The disclosure relates to a method for forming aryl carbon-nitrogen bonds and to photoreactors useful in these and other light-driven reactions. The method comprises contacting an aryl halide with an amine in the presence of a Ni salt catalyst solution and an optional base, thereby forming a reaction mixture; exposing the reaction mixture to light under reaction condition sufficient to produce the aryl carbon-nitrogen bonds. In certain embodiments, the amine may be present in a molar excess to the aryl halide. In certain embodiments, the Ni salt catalyst solution includes a Ni(II) salt and a polar solvent, wherein the Ni(II) salt is dissolved in the polar solvent. In certain embodiments, the reactions conditions include holding the reaction mixture at between about room temperature and about 80° C. for between about 1 hour and about 20 hours such that at least about 50% yield is obtained.
Type:
Application
Filed:
May 6, 2019
Publication date:
November 14, 2019
Applicant:
Colorado State University Research Foundation
Inventors:
Garret Miyake, Chern-Hooi Lim, Max Kudisch, Bin Liu
Abstract: Embodiments for systems and methods for third party assessment related to the evaluation of risks associated with third parties in which hacker conversations on websites are filtered and analyzed using keywords as input to uncover relevant forum and marketplace discussions are disclosed herein.
Type:
Application
Filed:
May 9, 2019
Publication date:
November 14, 2019
Applicant:
Arizona Board of Regents on Behalf of Arizona State University
Inventors:
Eric Nunes, Krishna Dharaiya, Jana Shakarian, Paulo Shakarian
Abstract: A method for independent real and reactive power flow control without sensing receiving end voltage in a power flow controller (PFC) includes calculating a first reference phase angle, calculating a first reference voltage, modifying the first reference phase angle calculated using a first phasor modifier, calculating a first reference current for a first terminal, calculating a second reference phase angle for current through the first terminal, calculating a second reference voltage across a second CMI by subtracting voltages at the first terminal and a second terminal, and controlling the first CMI and the second CMI for controlling the power flow through the PFC.
Type:
Grant
Filed:
August 4, 2016
Date of Patent:
November 12, 2019
Assignee:
Board of Trustees of Michigan State University
Inventors:
Fang Z. Peng, Shuitao Yang, Deepak Gunasekaran
Abstract: The invention relates to microfluidic devices and array disks for “one-pot” isolated chemical reactions. The array disks comprise a plurality of sectors in which each sector comprises one microfluidic device. The microfluidic devices comprise a fluid delivery channel and an array of wells wherein the fluid delivery channel delivery fluid into the wells in a serpentine arrangement. In some embodiments, the fluid delivery channel is directly above the array of wells. In other embodiments, the fluid delivery channel is offset from the array of wells so that side channels branching from the fluid delivery channel delivers fluid into the wells. The well of the microfluidic device comprises a gas-permeable membrane that forms the floor, well, or at least a portion of the floor or wall of the well. In preferred embodiments, the well is cylindrical.
Type:
Grant
Filed:
July 13, 2018
Date of Patent:
November 12, 2019
Assignee:
Arizona Board of Regents on behalf of Arizona State University
Abstract: Systems, methods, and apparatus for large scale, high throughput phenotyping of items including plants to derive environment/genetics correlations based on controlled variation of environment. Spatial and temporal resolution is improved by an integrated system that can use space efficiently yet concurrently process a large number of replicates but in varying environments. This is accomplished by using an array of miniature greenhouses, each in communication with one or more generators or regulators of an environmental factor that can be independently supplied and controlled to each miniature greenhouse. The controller also controls acquisition of data from each greenhouse as well as processing of that data into phenomic/genomic correlations.
Type:
Grant
Filed:
June 12, 2015
Date of Patent:
November 12, 2019
Assignee:
Iowa State University Research Foundation, Inc.
Abstract: A new and distinct Hop plant cultivar named ‘OR91331’ is disclosed, characterized by having an early mature date, resistance to downy mildew (Pseudoperonospora humuli [Miyabe & Takah.] G. W. Wilson) and powdery mildew (Podosphaera macularis [Wallr.] U. Braun & S. Takam); vigorous with high yield potential; high alpha acids; high oil content; and high amounts of some essential oil components implicated in driving beer flavor and aroma such as myrcene, cymene, methyl heptanoate, linalool, citronellol, and terpineol.