Patents Assigned to State University
  • feruloyl-coa:monolignol transferase
    Patent number: 9493783
    Abstract: The invention relates to isolated nucleic acids encoding a feruloyl-CoA:monolignol transferase and feruloyl-CoA:monolignol transferase enzymes. The isolated nucleic acids and/or the enzymes enable incorporation of monolignol ferulates into the lignin of plants, where such monolignol ferulates include, for example, p-coumaryl ferulate, coniferyl ferulate, and/or sinapyl ferulate. The invention also includes methods and plants that include nucleic acids encoding a feruloyl-CoA:monolignol transferase enzyme and/or feruloyl-CoA:monolignol transferase enzymes.
    Type: Grant
    Filed: October 4, 2012
    Date of Patent: November 15, 2016
    Assignees: Board of Trustees of Michigan State University, The University of British Columbia, Wisconsin Alumni Research Foundation
    Inventors: Curtis Wilkerson, John Ralph, Saunia Withers, Shawn D. Mansfield
  • Structurally reinforced optically transparent bulletproof panel
    Patent number: 9494389
    Abstract: A structurally reinforced optically transparent panel that may be utilized as a bulletproof window or shield. The panel includes a plurality of angled reinforcement members having a reflective top and bottom surfaces. Optical lenses are disposed between the reinforcement members directing a light ray in a predetermined direction. The geometry and spacing of the reinforcement members is such that the light rays enter and exit the bulletproof panel at substantially the same angle allowing an observer to view optical images of objects behind the bulletproof panel, thus creating optical transparency. The reinforcement members are of a high strength material capable of being impenetrable by a projectile fired from a ballistic weapon or an explosion debris.
    Type: Grant
    Filed: October 16, 2015
    Date of Patent: November 15, 2016
    Assignee: The Florida State University Research Foundation, Inc.
    Inventor: Alexey Kovalev
  • Serum MG53 as a diagnostic marker for tissue injury
    Patent number: 9494602
    Abstract: Disclosed herein are compositions and methods for measuring the level of MG53 found in a biological fluid as a biomarker for a disease or disorder, e.g., tissue damage, exercise capacity or a muscle-related disease or disorder. In addition, the invention relates to targeting the native MG53 found in the blood as a therapeutic approach.
    Type: Grant
    Filed: March 14, 2013
    Date of Patent: November 15, 2016
    Assignee: Rutgers, The State University of New Jersey
    Inventors: Noah Weisleder, Jianjie Ma
  • Inhibitors of PFKFB3 for cancer therapy
    Patent number: 9492418
    Abstract: Compounds used to inhibit glycolytic pathway small molecule kinase 6-Phosphofructo-2-kinase/Fructose-2,6-bisphosphatase (PFKFB) are set forth; these inhibitors can be used in the treatment of certain diseases in which cells or tumors rely on glycolytic metabolism, such as many cancer cells.
    Type: Grant
    Filed: May 9, 2012
    Date of Patent: November 15, 2016
    Assignee: Board of Supervisors of Louisiana State University And Agricultural and Mechanical College
    Inventors: Yong-Hwan Lee, Jeong Do Kim
  • Quinoline derivatives and uses thereof
    Patent number: 9493420
    Abstract: This disclosure provides a new class of compounds referred to as “reversed chloroquines” (RCQs), which are highly effective against CQR and CQS malaria parasites. RCQs are hybrid molecules, which include an antimalarial quinoline analog (such as chloroquine) moiety and a CQR reversal moiety. Exemplary RCQ chemical structures are provided. Also provided are pharmaceutical compositions including the disclosed RCQ compounds, and methods of using such compounds and compositions for the treatment of malaria and inhibition of CQR or CQS Plasmodium sp. (such as P. falciparum).
    Type: Grant
    Filed: July 25, 2013
    Date of Patent: November 15, 2016
    Assignee: Portland State University
    Inventors: David H. Peyton, Steven Burgess
  • Apparatus and clutch for using controlled storage and release of mechanical energy to aid locomotion
    Patent number: 9492302
    Abstract: The subject matter described herein includes an apparatus and a clutch for using controlled storage and release of mechanical energy to aid in locomotion. One exemplary apparatus includes a frame including an upper portion configured to mechanically couple to a leg of the subject on a calf side of an ankle joint of the subject and a lower portion pivotally attached to the upper portion configured to mechanically couple to a foot of the subject on a foot side of the ankle joint of the subject. The apparatus include a rotary clutch and an elastic element coupled between the upper and lower portions of the frame to control periods of energy storage and release by the elastic element.
    Type: Grant
    Filed: August 15, 2012
    Date of Patent: November 15, 2016
    Assignee: North Carolina State University
    Inventors: Michael B. Wiggin, Gregory S. Sawicki, Steven H. Collins
  • Soy adhesives and composites made from the adhesives
    Patent number: 9493693
    Abstract: A formaldehyde-free aqueous adhesive composition comprising (a) soy protein and (b) magnesium oxide or a mixture of magnesium oxide and magnesium hydroxide, wherein components (a) and (b) together constitute at least 50 weight percent of the composition, excluding the weight of the water.
    Type: Grant
    Filed: September 15, 2011
    Date of Patent: November 15, 2016
    Assignee: Oregon State University
    Inventor: Kaichang Li
  • Reaction-based fluorescent probes for sulfane sulfur and the application in bioimaging
    Patent number: 9494592
    Abstract: Reaction-based fluorescent probes are provided which detect, for example, biologically important sulfane sulfur species (persulfide, polysulfide, and elemental sulfur) in, for example, complex and living systems. The probes are high in selectivity and sensitivity to sulfane sulfurs. Moreover, probes are suitable for bioimaging sulfane sulfurs in living cells.
    Type: Grant
    Filed: April 11, 2014
    Date of Patent: November 15, 2016
    Assignee: Washington State University
    Inventors: Ming Xian, Wei Chen
  • Thermosetting shape memory polymers with ability to perform repeated molecular scale healing
    Patent number: 9493643
    Abstract: A composition comprising thermoset shape memory polymer and a composition for molecular scale healing is disclosed; the composition has the ability to resolve structural defects by a close-then-heal mechanism. In use the shape memory polymer serves to bring opposing surfaces in a structural defect into proximity, whereafter heating the molecular scale healing composition to a level at or above its melting point allows for molecular scale healing. The composition has the ability to close macroscopic defects, and to do so repeatedly even if another wound occurs in a previously healed area.
    Type: Grant
    Filed: May 4, 2012
    Date of Patent: November 15, 2016
    Assignee: Board of Supervisors of Louisiana State University And Agricultural and Mechanical College
    Inventor: Guoqiang Li
  • Microcin and uses thereof
    Patent number: 9492500
    Abstract: Microcin MccPDI and bacteria harboring the mcpM gene which encodes MccPDI, limit growth of and/or kill pathogenic bacteria such as pathogenic Escherichia coli (E. coli) and/or Shigella bacteria via proximity-dependent inhibition (PDl).
    Type: Grant
    Filed: June 14, 2013
    Date of Patent: November 15, 2016
    Assignee: Washington State University
    Inventors: Douglas R. Call, Lauren Eberhart, Kelly A. Brayton, Thomas E. Besser, Ashish Sawant, Lisa Orfe
  • DEVICE FOR NEUROPROSTHETICS WITH AUTONOMOUS TUNABLE ACTUATORS
    Publication number: 20160324476
    Abstract: A microelectromechanical device and method for neuroprosthetics comprises microactuators and microelectrodes. The microelectrodes are to be positioned in a nerve bundle and bonded with the microactuators through an interconnect. The position of each of the microactuators can be individually tuned through control signals so that the microelectrodes are implanted at desired positions in the nerve bundle. The control signals are transmitted to the microactuators and generated with a open-loop or closed-loop control scheme that uses signals acquired by the microelectrodes from the nerve bundle as feedback.
    Type: Application
    Filed: April 22, 2016
    Publication date: November 10, 2016
    Applicant: Arizona Board of Regents on behalf of Arizona State University
    Inventors: Jitendran Muthuswamy, Sivakumar Palaniswamy
  • RECOMBINANT LACTOBACILLUS WITH DECREASED LIPOTEICHOIC ACID TO REDUCE INFLAMMATORY RESPONSES
    Publication number: 20160324905
    Abstract: Methods and compositions for treating or preventing inflammatory disorders are provided. The compositions of the invention comprise a recombinant bacterium genetically modified to decrease the display of lipoteichoic acid on the cell surface. Methods of the invention comprise administering to a subject a recombinant bacterium modified to decrease the display of lipoteichoic acid on the cell surface. Administration of the recombinant bacterium promotes a desired therapeutic response. The recombinant bacterium may be administered in a single dose or series of doses. Methods of the invention find use in treating or preventing a variety of inflammatory disorders including, for example, treating or preventing inflammatory bowel disease, colitis, or Crohn's disease.
    Type: Application
    Filed: April 13, 2016
    Publication date: November 10, 2016
    Applicants: North Carolina State University, Northwestern University
    Inventors: Todd R. Klaenhammer, Erika Pfeiler, Mansour Mohamadzadeh
  • METHOD OF PATTERNING ELECTRICALY-CONDUCTIVE FILM ON A FLEXIBLE SUBSTRATE
    Publication number: 20160325457
    Abstract: A method of patterning a combined layer of an electrically-conductive film, such as indium-tin-oxide (ITO), that is disposed on a flexible substrate includes bending the combined layer about a radius of curvature. The combined layer is initially bent in a first direction so that the electrically-conducive film is distal to the radius of curvature, so as to form initial dielectric lines in the electrically-conductive film. The combined layer is then bent in another direction so that the electrically-conductive film is proximate to the radius of curvature to further enhance the dielectric performance of the initial dielectric lines. The dielectric lines electrically isolate a portion of the electrically-conductive film that is disposed therebetween, to form an electrically conductive electrode.
    Type: Application
    Filed: December 30, 2014
    Publication date: November 10, 2016
    Applicant: Kent State University
    Inventors: John WEST, Paul Anders OLSON, Da-Wei LEE
  • Multi-stage programmable rectifier with efficiency tracking
    Patent number: 9490725
    Abstract: Examples of multi-stage programmable rectifiers are provided herein. Each rectifier stage can include a first transistor and a switch connected to the first transistor. A threshold voltage of the first transistor can be programmed through selection of one of a plurality of voltages available at the switch. Each rectifier stage can also include a second transistor that can be connected in series with the first transistor. An output capacitor can be connected to the second transistor at an output of the rectifier stage. The plurality of voltages provided at the switch allows the threshold voltage of the first transistor to be adjusted in either a positive or negative position to increase efficiency of the rectifier. A calibration process can be used to identify the position of each switch in the rectifier stages that results in the highest efficiency or rectifier output voltage.
    Type: Grant
    Filed: March 14, 2014
    Date of Patent: November 8, 2016
    Assignee: Oregon State University
    Inventors: Lingli Xia, Patrick Y. Chiang, Jiao Cheng
  • Cognitive map-based decision simulation for training (CMDST)
    Patent number: 9489631
    Abstract: Disclosed is a Cognitive Map-Based Tactical Decision Simulation for Training (CMDST) uses fuzzy cognitive maps (FCM's) to: 1) model high-stress tactical problems or engagements and their causal relationships; 2) simulate situational activities immediately prior to, during, and following the occurrence of a tactical problem or engagement; 3) calculate the relative values of different courses of action; 4) perform individual performance and comparative analysis of selected courses of action; 5) conduct after action reviews to solidify lessons learned from the simulation; and 6) develop individual decision making action plans to outline specific actions to be undertaken to improve future decision making performance.
    Type: Grant
    Filed: July 1, 2013
    Date of Patent: November 8, 2016
    Assignee: Columbus State University Research Service Foundation, Inc.
    Inventors: Mohammed Shamimur Rahman Khan, Osama George Khouri, Wayne Charles Summers, Rodrigo Obando, Vladimir Zanev, Sebastian Wankun Khor, Robert Smith
  • Feruloyl-CoA:monolignol transferase
    Patent number: 9487794
    Abstract: The invention relates to nucleic acids encoding a feruloyl-CoA:monolignol transferase and the feruloyl-CoA:monolignol transferase enzyme that enables incorporation of monolignol ferulates, for example, including p-coumaryl ferulate, coniferyl ferulate, and sinapyl ferulate, into the lignin of plants.
    Type: Grant
    Filed: July 22, 2011
    Date of Patent: November 8, 2016
    Assignees: Board of Trustees of Michigan State University, The University of British Columbia, Wisconsin Alumni Research Foundation
    Inventors: Curtis Wilkerson, John Ralph, Saunia Withers, Shawn D. Mansfield
  • Fire alarm system
    Patent number: 9489814
    Abstract: A fire alarm control and monitoring system is disclosed. In some embodiments, the fire alarm and control system may include a plurality of fire alarm control panels connected together through a communication network. In some embodiments, the fire alarm control panels may communicate using a token passing protocol yet be arranged in a tree network topology.
    Type: Grant
    Filed: February 22, 2016
    Date of Patent: November 8, 2016
    Assignee: Colorado State University Research Foundation
    Inventors: Aaron R. Pettigrew, Brian T. Sedlak, Scott A. Seeley
  • Robust, low power, reconfigurable threshold logic array
    Patent number: 9490815
    Abstract: A field programmable threshold-logic array (FPTLA) includes a number of threshold logic gates and a number of programmable interconnect elements. Each one of the programmable interconnect elements are connected between two or more of the threshold logic gates, such that the programmable interconnect elements route signals between the threshold logic gates. By using threshold logic gates for the FPTLA, the size of the FPTLA may be significantly smaller than conventional solutions. Further, using threshold logic gates results in significant improvements in the computation speed of the FPTLA when compared to conventional solutions.
    Type: Grant
    Filed: July 8, 2014
    Date of Patent: November 8, 2016
    Assignee: Arizona Board of Regents on behalf of Arizona State University
    Inventors: Sarma Vrudhula, Niranjan Kulkarni
  • Magnetic data storage using induced strain of a magnetostrictive material
    Patent number: 9489973
    Abstract: Acoustically assisted magnetic recording can be used in a hard disk drive or a solid state medium. In the described embodiments, otherwise unwriteable high-coercivity media are made amenable to recording by lowering their coercivity via strain induced by acoustic waves. The use of acoustic waves temporarily and locally reduces the magnetic field required to record information on a magnetic recording medium. The process makes use of the magnetostrictive property of a magnetic material by which the magnetic anisotropy of the material is changed by strain. The result of such a change is a reduction in the coercive field, i.e., the magnetic field required to reverse the magnetization direction. Because acoustic waves cause strain, the passage of an acoustic wave through a magnetic material can be used to reduce its coercive field.
    Type: Grant
    Filed: February 13, 2014
    Date of Patent: November 8, 2016
    Assignee: Oregon State University
    Inventors: Pallavi Dhagat-Jander, Albrecht Jander
  • Polymer foam-based piezoelectric materials and method of manufacture
    Patent number: 9490420
    Abstract: Thermally stable piezoelectric polymer foams (ferroelectrets) with high piezoelectric activity for sensing and actuation. The invention further includes a method of fabricating such foams in an environmentally friendly manner.
    Type: Grant
    Filed: August 17, 2015
    Date of Patent: November 8, 2016
    Assignee: The Florida State University Research Foundation, Inc.
    Inventors: Changchun Zeng, Yan Li