Abstract: Composite materials are provided that include one or more CNT yarns embedded in a matrix material. The composite materials may be transparent. Methods for making the composite materials are also provided. The composite materials may be made by arranging at least one CNT yarn into a desired pattern and embedding the at least one CNT yarn into a matrix material.

Abstract: The present invention provides isolated polynucleotides that can serve as translation enhancing elements and their use in protein expression reagents and methods.

Abstract: A method of patterning an electrically-conductive film is performed by providing a flexible substrate that carries the electrically-conductive film thereon to form a combined layer. The combined layer is then bent about a radius of curvature, so as to impart a stress on the brittle conductive film along the axis of curvature of the curved surface. The application of the stress to the conductive film results in the formation of crack lines that are substantially perpendicular to the direction to which the substrate and conductive film are bent. The crack lines serve to define and electrically isolate conductive sections therebetween that can be utilized as electrodes and address lines in electronic devices.

Abstract: CXCR4 and ROBO-1 are biomarkers associated with type 1 diabetes. Expression of CXCR4 and ROBO-1 in peripheral CD3 T cells is substantially higher in patients with autoimmune diabetes (type 1 diabetes) than in non-diabetic patients. Therapies are disclosed for reducing the progression of type 1 diabetes, and to reduce the risk of developing type 1 diabetes in patients who are at risk of developing type 1 diabetes.

Abstract: A robust method to automatically segment and identify tumor regions in medical images is extremely valuable for clinical diagnosis and disease modeling. In various embodiments, an efficient algorithm uses sparse models in feature spaces to identify pixels belonging to tumorous regions. By fusing both intensity and spatial location information of the pixels, this technique can automatically localize tumor regions without user intervention. Using a few expert-segmented training images, a sparse coding-based classifier is learned. For a new test image, the sparse code obtained from every pixel is tested with the classifier to determine if it belongs to a tumor region. Particular embodiments also provide a highly accurate, low-complexity procedure for cases when the user can provide an initial estimate of the tumor in a test image.

Abstract: Threshold logic elements and methods of operating the same are disclosed. In one embodiment, a threshold logic element includes a first input gate network configured to receive a first set of logical signals, a second input gate network configured to receive a second set of logical signals. The differential sense amplifier is operably associated with the first input gate network and the second input gate network such that the differential sense amplifier is configured to generate a differential logical output in accordance with a threshold logic function. In order to make the threshold logic element more robust, the differential sense amplifier is configured to feed back the differential logical output to the first input gate network and the second input gate network. By providing the differential logical output as feedback, floating node issues are avoided and the threshold logic element is more resistant to noise.

Abstract: This disclosure relates generally to threshold logic elements for integrated circuits (ICs). In one embodiment, a threshold logic element has a first input gate network, a second input gate network, a differential sense amplifier, and a resistive network. The first input gate network is configured to receive a first set of logical signals, while the second input gate network configured to receive a second set of logical signals. The differential sense amplifier is operably associated with the first input gate network and the second input gate network such that the differential sense amplifier is configured to generate a differential output in accordance with a threshold logic function. The resistive network is coupled between the differential sense amplifier and the first input gate network and between the differential sense amplifier and the second input gate network. The resistive network makes the threshold logic element less susceptible to process variations.

Abstract: Described are nonlinear optical (NLO) crystals, including aluminum-borate NLO crystals, that have low concentrations of contaminants that adversely affect the NLO crystal's optical properties, such as compounds that contain transition-metal elements and/or lanthanides, other than yttrium, lanthanum, and lutetium. Some NLO crystals with low concentrations of these contaminants are capable of second harmonic generation at very short wavelengths. Also described are embodiments of a method for making these NLO crystals. Some embodiments involve growing a single NLO crystal, such as an aluminum-borate NLO crystal, from a mixture containing a solvent that is substantially free of harmful contaminants. The described NLO crystals can be used, for example, in laser devices.

Abstract: Compositions and methods for reducing the level of nornicotine and N?-nitrosonornicotine (NNN) in Nicotiana plants and plant parts thereof are provided. The compositions comprise isolated polynucleotides and polypeptides for cytochrome P450s that are involved in the metabolic conversion of nicotine to nornicotine in these plants. Expression cassettes, vectors, plants, and plant parts thereof comprising inhibitory sequences that target expression or function of the disclosed cytochrome P450 polypeptides are also provided. Methods for the use of these novel sequences to inhibit expression or function of cytochrome P450 polypeptides involved in this metabolic conversion are also provided. The methods find use in the production of tobacco products that have reduced levels of nornicotine and its carcinogenic metabolite, NNN, and thus reduced carcinogenic potential for individuals consuming these tobacco products or exposed to secondary smoke derived from these products.

Abstract: A processor comprising: an instruction processing pipeline, configured to receive a sequence of instructions for execution, said sequence comprising at least one instruction including a flow control instruction which terminates the sequence; a hash generator, configured to generate a hash associated with execution of the sequence of instructions; a memory configured to securely receive a reference signature corresponding to a hash of a verified corresponding sequence of instructions; verification logic configured to determine a correspondence between the hash and the reference signature; and authorization logic configured to selectively produce a signal, in dependence on a degree of correspondence of the hash with the reference signature.

Abstract: The invention relates to a new method of texturing silicon surfaces suited for antireflection based on ion implantation of hydrogen and heavy ions or heavy elements combined with thermal annealing or thermal annealing and oxidation. The addition of the heavy ions or heavy elements allows for a more effective anti-reflective surface than is found when only hydrogen implantation is utilized. The methods used are also time- and cost-effective, as they can utilize already existing semiconductor ion implantation fabrication equipment and reduce the number of necessary steps. The antireflective surfaces are useful for silicon-based solar cells.

Abstract: Compositions and methods for reducing the level of nornicotine and N?-nitrosonornicotine (NNN) in Nicotiana plants and plant parts thereof are provided. The compositions comprise isolated polynucleotides and polypeptides for cytochrome P450s that are involved in the metabolic conversion of nicotine to nornicotine in these plants. Expression cassettes, vectors, plants, and plant parts thereof comprising inhibitory sequences that target expression or function of the disclosed cytochrome P450 polypeptides are also provided. Methods for the use of these novel sequences to inhibit expression or function of cytochrome P450 polypeptides involved in this metabolic conversion are also provided. The methods find use in the production of tobacco products that have reduced levels of nornicotine and its carcinogenic metabolite, NNN, and thus reduced carcinogenic potential for individuals consuming these tobacco products or exposed to secondary smoke derived from these products.

Abstract: A real-time ophthalmoscope system for imaging an eye includes a wide field scanning light ophthalmoscope (SLO) configured for wide field imaging of the eye. The system also includes a small field SLO configured for high resolution imaging of the eye. A 2D tracking minor electrically coupled to a computer, and a 2D steering minor electrically coupled to the computer, are both disposed in an optical path between the small field SLO and the eye. The system is configured to acquire a plurality of small field images at a plurality of locations on the eye as defined by the 2D steering minor, each of the small field images is stabilized for a motion of the eye by the 2D tracking minor. A method for imaging of the eye is also described.

Abstract: A dynamic spinal stabilization device for the treatment of high-grade spinal disorders is disclosed herein. The dynamic spinal stabilization device includes two or more screw assemblies, each of which include a pedicle screw and a head socket containing a curved internal track that limits the range of motion and center of rotation of the spinal segments stabilized using the device to the physiological levels of a nondegraded spinal segment.

Abstract: A microfibrillar high molecular weight chitosan-based textile can be used as a hemostat. The chitosan has been treated in a nitrogen field by applying energy to ionize nitrogen in and around the chitosan textile. A single or multiple such treatments may be employed. For example, the chitosan textile may be irradiated under nitrogen using ?-irradiation, treated under a nitrogen plasma, or both.

Abstract: A method for controlling the attachment and growth of cells on a surface of an article, the method comprising contacting the article with living tissue, living organisms, or with water in an aqueous system comprising living organisms wherein the article comprises a substratum having a surface and a film on the surface, the film comprising a network of a net positively charged composition and a net negatively charged composition, wherein the net positively charged composition comprises a net positively charged polyelectrolyte or the net negatively charged composition comprises a net negatively charged polyelectrolyte, and the net positively charged polyelectrolyte or the net negatively charged polyelectrolyte contain (i) a polymer repeat unit having at least two fluorine atoms, or (ii) a polymer repeat unit having a zwitterion group.

Abstract: A system and method for layer-by-layer quantification of the remodeling of the human fovea comprises finding a fixed reference point in inner retina, measuring the thickness of the inner retina at the fixed reference point, for a range of finely sampled distances starting from the fixed reference point, measuring the thickness, comparing the measured thickness with a normative base and obtaining a plurality of curves, evaluating area for each curve and defining a distance from the fixed reference having highest sensitivity with respect to the fixed reference point compared to the normative base, displaying a 3D re-creation of foveal architecture-based color-coded picture in accordance with the measured thickness at each finely sampled distance, entering the measured thickness into a model having parameters, obtaining numerical solutions for each parameter, and defining percent change of the parameters for the patient versus the parameters for the control.

Abstract: Embodiments of probes for selectively detecting compounds having a thiol group and an amino group, e.g., cysteine and/or homocysteine, are disclosed, along with methods and kits for detecting the compounds in neutral media with the probes. The probes have a structure according to the general formula where R1-R4 independently are hydrogen hydroxyl, halogen, thiol, thioether, lower aliphatic, or lower alkoxy, x is an integer from 0 to 4, and each R5 independently is halogen, hydroxyl, thiol, thioether, lower aliphatic, or lower alkoxy. Embodiments of the disclosed probes are capable of undergoing condensation/cyclization reactions with cysteine and/or homocysteine. Cysteine and/or homocysteine can be selectively detected and identified by determining fluorescence emission of the probes at characteristic wavelengths.

Abstract: Phenoxyalkyl pyridinium oxime compounds for use in treating organophosphate poisoning.

Abstract: The invention provides a compound of formula I: or a salt or prodrug thereof, wherein Y, W, Z, Z1, Z2, Z3, Z4, and R1-R12 have any of the values described in the specification, as well as compositions comprising a compound of formula I. The compounds are useful as antibacterial agents.