Abstract: Methods of converting cellulose or related biorenewable carbohydrate materials into high-value chemical compounds. The methods provide a means of converting low-cost materials such as cellulose and biomass into high yields of compounds such as ethylene glycol, propylene glycol, glycerin, methanol, hydroxyacetone, glycolaldehyde and dihydroxyacetone.
Type:
Grant
Filed:
August 24, 2012
Date of Patent:
April 1, 2014
Assignee:
Iowa State University Research Foundation, Inc.
Inventors:
Walter S. Trahanovsky, Ronald C. Holtan, Kyle W. Quasdorf, Norman K. Olson, Alyse A. Dilts, Joseph A. Marshall
Abstract: A power module assembly includes a reactor core immersed in a coolant and a reactor vessel housing the coolant and the reactor core. An internal dry containment vessel submerged in liquid substantially surrounds the reactor vessel in a gaseous environment. During an over-pressurization event the reactor vessel is configured to release the coolant into the containment vessel and remove a decay heat of the reactor core through condensation of the coolant on an inner surface of the containment vessel.
Type:
Grant
Filed:
November 15, 2007
Date of Patent:
April 1, 2014
Assignee:
The State of Oregon Acting by and Through the State Board of Higher Education on Behalf of Oregon State University
Abstract: Following a diagnosis of ectopic pregnancy, at least one aromatase inhibitor, is administered to a patient, either alone or in combination with other aromatase inhibitors or therapeutic agents or as an adjuvant to conservative surgical treatment, such as laparoscopy, to prevent the establishment and/or continuation of the ectopic pregnancy. In certain preferred embodiments, the aromatase inhibitor is administered in conjunction with methotrexate.
Type:
Grant
Filed:
October 4, 2005
Date of Patent:
April 1, 2014
Assignee:
Wayne State University
Inventors:
Mohamed F. M. Mitwally, Michael P. Diamond, Robert F. Casper
Abstract: The present invention relates to a composition and methods of treatment for inflammation comprising of adult stem cells and inflammatory cytokines. The invention further relates to the treatment of inflammation associated with autoimmune disorders, allergies, sepsis, cancer as well as to preventing, reducing or treating transplant rejection and/or graft-versus-host disease (GvHD).
Type:
Grant
Filed:
January 30, 2009
Date of Patent:
April 1, 2014
Assignee:
Rutgers The State University of New Jersey
Abstract: An apparatus for capillary zone electrophoresis includes a polyelectrolyte multilayer positioned in a capillary tube for analytical separations of macromolecules. The capillary comprises a passage defined by passage walls comprising fused silica and the polyelectrolyte multilayer positioned within the passage. The polyelectrolyte multilayer comprises layers with alternating charge. The apparatus includes a power supply having a positive electrode and a negative electrode for generating an electric field therebetween and a sensor positioned adjacent the passage for sensing macromolecules.
Type:
Grant
Filed:
October 18, 2007
Date of Patent:
April 1, 2014
Assignee:
The Florida State University Research Foundation, Inc.
Abstract: Methods are described for addressing the bowing and/or warping of flexible substrates, attached to a rigid carrier, which occurs as a result of the thermal challenges of semiconductor processing. In particular, viscoelastic adhesives are provided which can bond a flexible substrate to a rigid carrier and mediate the thermal mismatch which often is present due to the distinctly different materials properties of most flexible substrates, such as plastic films, with respect to rigid carriers, such as silicon wafers. Assemblies are also provided which are produced according to the methods described herein.
Type:
Grant
Filed:
April 6, 2009
Date of Patent:
April 1, 2014
Assignee:
Arizona Board of Regents, a body corporate of the State of Arizona, Acting for and on Behalf of Arizona State University
Inventors:
Shawn O'Rourke, Douglas Loy, Hanqing Jiang
Abstract: A method for coating for a substrate, comprising applying an underlayer of a self assembling monolayer well ordered array of long chain molecules on the substrate; and applying a top layer, over the underlayer, wherein the self-assembling monolayer well ordered array serves as a molecular template organizing formation of said top layer, comprising at least one of a thermally-resistant polymer layer over said self assembling monolayer selected from the group consisting of epoxies, and phosphorus-based polyimides; and a metal oxide, metal nitride, or a ceramic. The self assembling monolayer may be selectively applied to a portion of the substrate, leaving an uncoated region, and the top layer formed only over the areas of the substrate coated with the self-assembling monolayer, resulting in at least one region of the substrate which is not coated with the top layer.
Type:
Grant
Filed:
April 16, 2012
Date of Patent:
April 1, 2014
Assignee:
The Research Foundation for The State University of New York
Inventors:
Junghyun Cho, Scott Oliver, Wayne Jones, Bahgat Sammakia
Abstract: The invention provides therapeutics and methods to induce a mammalian host, including a human, to produce antibodies, which agonize death receptors and cause the apoptotic death of target cells within the host's body. The therapeutics are vaccine compositions, including genetic vaccines encoding death receptor antigens of the tumor necrosis factor receptor family. Also provided are means and methods for overcoming host immunological tolerance to death receptors. The vaccines are useful against cancer cells and other death receptor bearing target cells within the host, and can be used in both therapeutic and prophylactic settings. The vaccines are also useful for diagnostic testing of the immunocompetence of a host.
Type:
Grant
Filed:
November 6, 2009
Date of Patent:
April 1, 2014
Assignee:
Wayne State University
Inventors:
Wei-Zen Wei, Gen Sheng Wu, Marie P. Piechocki, Richard F. Jones
Abstract: Preferred embodiments relate to compositions of inherently radiopaque, biocompatible, bioresorbable polymeric particles and methods of using them for embolizing a body lumen.
Type:
Grant
Filed:
September 27, 2004
Date of Patent:
April 1, 2014
Assignee:
Rutgers, The State University of of New Jersey
Inventors:
Donald K. Brandom, Eric Schmid, Joan Zeltinger, Durgadas Bolikal, Joachim B. Kohn
Abstract: The present invention generally relates to methods and systems for analysis of real-time user-generated text messages. The methods and systems allow analysis to be performed using term associations and geographical and temporal constraints.
Type:
Grant
Filed:
February 16, 2011
Date of Patent:
April 1, 2014
Assignee:
Wright State University
Inventors:
Amit Sheth, Karthik Gomadam, Meenakshi Nagarajan
Abstract: Methods, apparatuses, and systems for collecting samples using hybrid porous materials that include an organic material and an inorganic material. A method for sample collection includes contacting a hybrid porous material and a biological sample to the porous material. The hybrid porous material includes an inorganic material and an organic material. The method includes placing the porous material with the attached sample in a liquid medium, wherein the sample is separated from the porous material in the liquid medium to form a separated sample, and collecting the separated sample in the medium.
Type:
Grant
Filed:
August 14, 2009
Date of Patent:
April 1, 2014
Assignee:
Arizona Board of Regents, A body corporate of the State of Arizona Acting for and on Behalf of Arizona State University
Inventors:
Frederic Zenhausern, Ralf Lenigk, James Kinder, Jianing Yang
Abstract: A 23 amino acid peptide, AtPep1, plays an important role as a signaling component of the innate immune system of Arabidopsis. The peptide precursor gene is transcribed in response to elicitors generated by pathogens, and AtPep1 is produced to amplify the signaling pathways. Seven paralogs of the AtproPep1 gene have been identified in the Arabidopsis genome, and orthologs have been identified in species of several agriculturally important families. AtPep1 and its paralogs and orthologs play important roles as endogenous signals to amplify innate immunity. The sequences of two AtPep1 receptors from Arabidopsis are also provided.
Type:
Grant
Filed:
August 23, 2012
Date of Patent:
April 1, 2014
Assignee:
Washington State University Research Foundation
Inventors:
Gregory L. Pearce, Alisa Huffaker, Yube Yamaguchi, Patricia Louise Ryan
Abstract: The present invention relates to various methods to produce a variety of omega-3 fatty acids from various species of alga using crude glycerol as a substrate for algal growth. In one embodiment, the present invention relates to various methods to produced docosahexaenoic acid (DHA) from a Schizochytrium, Phaeodactylum, Thraustochytrid, Ulkenia, and/or Labyrinthulea species of alga. In another embodiment, the present invention relates to various methods to produced eicosapentaenoic acid (EPA) from a Schizochytrium, Phaeodactylum, Thraustochytrid, Ulkenia, and/or Labyrinthulea species of alga. In one instance, the methods of the present invention utilize crude glycerol as at least a portion of the culture medium for the various micro-organisms disclosed herein to enable the production of one or more omega-3 fatty acids.
Type:
Application
Filed:
November 27, 2013
Publication date:
March 27, 2014
Applicant:
Virginia Polytechnic Institute and State University
Abstract: A system and method for transferring agricultural material from a transferring vehicle to a storage portion of a receiving vehicle, and detecting and filling void areas of the agricultural material is disclosed. A transferring vehicle having a spout transfers agricultural material to a storage portion of a receiving vehicle. An imaging device associated with the transferring vehicle and facing towards the storage portion of the receiving vehicle collects imaging data. An image processing module is operable to, based on the imaging data, estimate fill levels of agricultural material within the storage portion; identify an area of the storage portion as targeted to fill; and identify a first void within the targeted area. A controller in communication with the image processing module is configured to command the spout to a position to direct agricultural material to the first void.
Type:
Application
Filed:
September 30, 2013
Publication date:
March 27, 2014
Applicants:
Iowa State University Research Foundation, Inc., Deere & Company
Inventors:
Matthew J. Darr, Robert McNaull, John Kruckeberg, Zachary T. Bonefas
Abstract: The present application relates generally to bio-adhesive components isolated from bio-oil prepared from animal waste, methods of preparation of the bio-adhesive components and uses thereof. Such uses include, but are not limited to, asphalt bio-binders, bio-adhesion promoters, asphalt bio-rejuvenators, asphalt bio-extenders, bio-asphalt as well as uses in roofing, soil stabilization, crack and joint sealing and flooring adhesives.
Type:
Application
Filed:
September 20, 2013
Publication date:
March 27, 2014
Applicant:
North Carolina Agricultural and Technical State University
Abstract: The present disclosure relates generally to therapeutic compositions comprising recombinant bacteria. Further, the disclosure elaborates upon methods of utilizing the taught therapeutic compositions to treat autoimmune and inflammatory disease. The present teachings also relate to the disclosed recombinant bacteria and methods of producing the recombinant bacteria utilized in the compositions and methods. Further taught herein are dietary supplements and food additive compositions comprising the taught recombinant bacteria.
Abstract: A method of treating pre-term labor in pregnant human patient expressing melatonin receptors in her myometrial cells comprises administering an inhibitor of MT2R, an inhibitor of protein kinase C, an inhibitor of phospholipase C, or a combination thereof to the patient.
Type:
Application
Filed:
May 17, 2013
Publication date:
March 27, 2014
Applicant:
The Florida State University Research Foundation, Inc.
Abstract: Chelating monomers and fluoride-releasing compositions are disclosed that may be incorporated into dental composite restorative materials, dental bonding agents or other dental materials, to produce materials with high fluoride release rates, and high fluoride recharge capability. Such dental restorative materials may help reduce the level of dental caries in patients, particularly the level of caries occurring on the margins of the restorative materials.
Type:
Application
Filed:
November 12, 2013
Publication date:
March 27, 2014
Applicant:
Board of Supervisors of Louisiana State University and Agricultural and Mechanical College
Abstract: Provided herein are OspA polypeptides from Lyme Disease-causing Borrelia having certain alteration(s). In one embodiment, the alteration(s) increase the conformational stability of the OspA polypeptide containing the alteration(s) while maintaining at least some of the antigenicity of the corresponding unaltered OspA polypeptide. In another embodiment, the altered OspA polypeptide has reduced cross-reactivity to hLFA-1, as compared to the corresponding unaltered OspA polypeptide.
Type:
Grant
Filed:
November 19, 2008
Date of Patent:
March 25, 2014
Assignees:
Brookhaven Sciences Associates, LLC, University of Rochester, Research Foundation of the State University of New York
Inventors:
Benjamin J. Luft, John J. Dunn, Shohei Koide, Catherine L. Lawson