Abstract: Indirect ELISAs to detect exposure to Felis catus gammaherpesvirus 1 (FcaGHV1) in domestic cats. These ELISAs detect feline serum antibodies to ORF52 and ORF38 of FcaGHV1. The ELISA assays are sensitive, specific, and adaptable for scale up use in high throughput diagnostics.
Type:
Grant
Filed:
July 19, 2018
Date of Patent:
November 21, 2023
Assignee:
Colorado State University Research Foundation
Inventors:
Susan VandeWoude, Kathryn R. Stutzman-Rodriguez, Ryan M. Troyer
Abstract: A composite article includes a lightning strike protection coating on a composite substrate. The lightning strike protection coating is formed from electrically conductive material and includes protrusions spaced along the length and width of a portion of the substrate surface. To form the lightning strike protection coating, a form is pressed against electrically conductive coating material on the composite substrate while the electrically conductive coating material is flowable. For example, the form can be a release film used in a composite vacuum bagging process. Suitable release film can have depressions along an inner surface that define an imprint of the coating protrusions. After curing, the coating can be covered with a layer of paint that conceals the protrusions but still allows lightning streamers to penetrate the paint at the protrusions.
Abstract: Various examples are provided related to machines utilizing heavy rare earth (HRE) free permanent magnets. In one example, a rotor assembly including a rotor core having a plurality of rotor slots and magnets positioned within the plurality of rotor slots. At least a portion of the magnets are free of heavy rare earth (HRE) elements. The magnets can include a combination HRE segments and HRE-free segments or can be free of HRE elements. The rotor assembly can be included in an electric machine such as, e.g., a permanent magnet (PM) machine.
Abstract: Various examples are provided related to modular multilevel converter (MMC) scale-up control methodologies which can be applied for MV and HV DC applications. In one example, an MMC includes first and second legs each with submodule (SM) groups connected in series, where each SM group includes a plurality of SMs; local group controllers that can control a corresponding SM group; and a central controller that can control output voltage of the MMC via the local group controllers. The local group controllers can provide capacitor voltage balancing (CVB) control of corresponding SM groups.
Type:
Grant
Filed:
June 24, 2021
Date of Patent:
November 21, 2023
Assignee:
NORTH CAROLINA STATE UNIVERSITY
Inventors:
Subhashish Bhattacharya, Mohammed Alharbi
Abstract: Systems and methods are provided for reducing peak-to-average power ratio (“PAPR”) in an orthogonal frequency division multiplexing (“OFDM”) signal having reference tones by introducing modified pilot tones to cancel peaks in OFDM symbols in the OFDM signal array. The modified pilot tones are added to the original OFDM signal, which in turn conditions the OFDM symbols of the signal to effectively reduce the PAPR. Such systems and methods provide PAPR reduction for OFDM signals generated by an OFDM Signal Processor through the addition of tone reservation PAPR reduction methods, which use reserved tones such as pilot tones to improve PAPR. Such methods offer an advantage of improving the PAPR without introducing distortion to the signal.
Abstract: A sputtering target having a unitary body. The unitary body includes a planar substrate plate and a toroidal portion extending from a top surface of the substrate plate. The toroidal portion reduces non-uniform erosion against the plate caused by a magnetic field applied to the target. In use, the magnetic field is initially received at the toroidal portion. After the magnetic field wears down the toroidal portion, the magnetic field is received at the substrate plate.
Type:
Grant
Filed:
December 17, 2020
Date of Patent:
November 21, 2023
Assignee:
YOUNGSTOWN STATE UNIVERSITY
Inventors:
Constantin Virgil Solomon, Christopher Yaw Bansah, Tom Nelson Oder
Abstract: This invention is directed to methods of switching from sexual reproduction to apomixis or from apomixis to sexual reproduction in a eukaryote. More particularly, this invention provides methods of switching from meiosis to apomeiosis and from syngamy to parthenogenesis in a plant. The invention also provides methods of producing an apomictic eukaryote from a sexual eukaryote and a sexual eukaryote from an apomictic eukaryote.
Type:
Grant
Filed:
February 11, 2019
Date of Patent:
November 21, 2023
Assignee:
Utah State University
Inventors:
John G. Carman, David Sherwood, Lei Gao
Abstract: The present disclosure provides nucleic acid compositions that incorporate one or more halouracil molecules. More specifically, the present disclosure reveals that the replacement of uracil nucleotides within a microRNA nucleotide sequence with a 5-halouracil increases the ability of the micro-RNA to inhibit cancer progression and tumorigenesis. As such, the present disclosure provides various nucleic acid (e.g., microRNA) compositions having 5-halouracil molecules incorporated in their nucleic acid sequences and methods for using the same. The present disclosure further provides pharmaceutical compositions comprising the modified nucleic acid compositions, and methods for treating cancers using the same.
Type:
Application
Filed:
January 25, 2023
Publication date:
November 16, 2023
Applicant:
The Research Foundation for The State University of New York
Abstract: Various systems, methods, and devices for identifying intraoperative bleeding are described. An example method includes identifying a first frame depicting a surgical scene; identifying a second frame depicting the surgical scene; identifying whether the second frame depicts bleeding by analyzing the first frame and the second frame; and outputting the second frame with an augmentation indicating whether bleeding is depicted in the second frame.
Type:
Application
Filed:
September 22, 2021
Publication date:
November 16, 2023
Applicants:
Wayne State University, RediMinds, Inc.
Inventors:
Abhilash K. Pandya, Mostafa Daneshgar Rahbar, Luke A. Reisner, Hao Ying, Mahendra Bhandari, Madhusudhan Reddiboina
Abstract: The present invention provides a compound, and method of selectively inhibiting the activity of a Fatty Acid Binding Protein (FABP) comprising contacting the FABP with a compound, said compound having the structure:
Type:
Application
Filed:
October 8, 2021
Publication date:
November 16, 2023
Applicant:
The Research Foundation for The State University of New York
Inventors:
Iwao Ojima, Martin Kaczocha, Monaf Awwa, Antonella Pepe
Abstract: Systems, methods, and non-transitory computer-readable storage media for an adjustable neural network. Systems measure feature applicability for an octave of a Convolutional Neural Network (CNN) at a standard scale, resulting in (1) at least one drop-off point where the octave no longer resonates with pre-defined features; and (2) a common drop-off between the CNN and at least one other CNN trained on at least one other separate domain. The system can then measure octave resonance for a plurality of CNNs trained on large data sets with a distribution of octaves for features, and measure a pattern of octaves learned in the CNN, resulting in a measurement pattern. The system can then compare that measurement pattern to the pre-defined features, resulting in a level of adaptability of the CNN, and modify the CNN based on the level of adaptability of the CNN, resulting in a modified CNN.
Type:
Application
Filed:
October 1, 2021
Publication date:
November 16, 2023
Applicant:
Board of Supervisors of Louisiana State University and Agricultural and Mechanical College
Inventors:
Supratik MUKHOPADHYAY, Edward COLLIER, Robert DIBIANO
Abstract: A system and methods for optically detecting a target gas are disclosed and described. An imaging system can include a narrow-band optical interference filter with a center wavelength that corresponds to a feature in an absorption spectrum of a target gas at a normal angle of incidence. An optical component can receive incoming light from the target gas that has passed through the narrow-band optical interference filter, where the narrow-band optical interference filter is tilted relative to the optical component, which tilt shifts the wavelength of light from each target point that is able to pass through the narrow-band optical interference filter. A camera can receive the incoming light that has been focused by the optical component. Multiple image frames are collected for different orientations of the system with respect to the target and analyzed to perform hyperspectral charactetization of target gas absorption.
Abstract: Described herein are polyhedral, three-dimensional tunable nanocages assembled with a multimeric protein covalently linked to a polynucleotide handle and a DNA origami base assembly including sequences complementary to the polynucleotide handles, wherein the polynucleotide handle and the complementary sequences hybridize to for double-stranded DNA helices.
Type:
Grant
Filed:
March 11, 2020
Date of Patent:
November 14, 2023
Assignee:
ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY
Abstract: Disclosed is a method of treating a tumor in a patient, comprising (a) administering riluzole in an amount effective to sensitize the tumor cells to ionizing radiation, and (b) irradiating the tumor cells with ionizing radiation in a dose effective to reduce tumor cell growth. The method can further comprise administering an effective amount of one or more additional therapeutic agents.
Type:
Grant
Filed:
December 8, 2021
Date of Patent:
November 14, 2023
Assignee:
RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY
Inventors:
Atif J. Khan, Suzie Chen, James S. Goydos, Bruce G. Haffty
Abstract: Redox catalysts having surface medication, methods of making redox catalysts with surface modification, and uses of the surface modified redox catalysts are provided. In some aspects, the redox catalysts include a core oxygen carrier region such as CaMnO3, BaMnO3??, SrMnO3??, Mn2SiO4, Mn2MgO4??, La0.8Sr0.2O3??, La0.8Sr0.2FeO3??, Ca9Ti0.1Mn0.9O3??, Pr6O11??, manganese ore, or a combination thereof; and an outer shell having an average thickness of about 1-100 monolayers surrounding the outer surface of the core region. The outer shell can include, for example a salt selected such as Li2WO4, Na2WO4, K2WO4, SrWO4, Li2MoO4, Na2MoO4, K2MoO4, CsMoO4, Li2CO3, Na2CO3, K2CO3, or a combination thereof.
Type:
Grant
Filed:
June 14, 2018
Date of Patent:
November 14, 2023
Assignee:
North Carolina State University
Inventors:
Fanxing Li, Luke Michael Neal, Yunfei Gao, Seif Yusuf, Ryan Dudek
Abstract: The disclosure discusses chiral dopants for liquid-crystalline materials. Chiral dopants can be bioreachable compounds, i.e. compounds produced from microbes through fermentation. Chiral dopants can also include bioreachable materials that are further modified by chemical synthetic steps. Chiral dopants as discussed herein can include biomolecules such as glycyrrhetinic acid (1), S-naringenin (2), shikimic acid (3), alpha-phellandrene (4), betulin (5), malic acid (6), valencene (7), or nootkatone (8), and any stereoisomers or chemically modified derivatives thereof. The disclosure further shows optical properties of such compounds in a liquid-crystalline material.
Type:
Grant
Filed:
December 6, 2019
Date of Patent:
November 14, 2023
Assignees:
Zymergen Inc., Kent State University
Inventors:
Adam Safir, Shilpa Naresh Raja, Arjan Zoombelt, Robert J. Twieg, Pawan Nepal, Ashani Wedige-Fernando, Peter Palffy-Muhoray
Abstract: Photoresist layers of semiconductor components including electric fields. The photoresist layer may include a body including a first portion disposed directly over a conductive layer of the semiconductor component. The body may also include a second portion integrally formed with and positioned over the first portion. The second portion may include a surface formed opposite the first portion. Additionally, the second portion may include a plurality of charged-particles implanted therein, where the plurality of charged-particles generating an electric field may extend through the first portion and the second portion of the body.
Type:
Grant
Filed:
January 11, 2021
Date of Patent:
November 14, 2023
Assignee:
THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK
Abstract: The disclosure relates to a thermoset omniphobic composition, which includes a thermoset polymer with first, second, and third backbone segments, urethane groups linking the first and third backbone segments, and urea groups linking the first and second backbone segments. The first, second, and third backbone segments generally correspond to urethane or urea reaction products of polyisocyanate(s), amine-functional hydrophobic polymer(s), and polyol(s), respectively. The thermoset omniphobic composition has favorable omniphobic properties, for example as characterized by water and/or oil contact and/or sliding angles. The thermoset omniphobic composition can be used as a coating on any of a variety of substrates to provide omniphobic properties to a surface of the substrate. Such omniphobic coatings can be scratch resistant, ink/paint resistant, dirt-repellent, and optically clear.
Type:
Grant
Filed:
September 10, 2021
Date of Patent:
November 14, 2023
Assignee:
BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY
Inventors:
Muhammad Rabnawaz, Fahad Khan, Nazim Uddin
Abstract: Embodiments of fiber substrate-based fluidic device and methods of manufacturing the same are described herein. In one example, a method of manufacturing a fiber substrate-based fluidic device comprises bonding a hydrophobic film that is substantially transparent to a laser beam (e.g., a film that transmits at least 80% of the incident radiant power of the laser beam) to a hydrophilic substrate and ablating the hydrophilic substrate with the laser beam without ablating the hydrophobic film to form one or more fluidly sealed channels in the hydrophilic substrate.