Patents Assigned to State University
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Patent number: 11739138Abstract: The present disclosure relates to constructs useful in expressing biotinylated monomers and tetramers produced from these monomers. The present disclosure also relates to methods for production and use of these tetramers in identifying and isolating antigen specific B cells and cloning antibodies thereto.Type: GrantFiled: December 21, 2021Date of Patent: August 29, 2023Assignees: Emory University, Rutgers, the State University of New JerseyInventors: Arash Grakoui, Joseph Marcotrigiano
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Patent number: 11738199Abstract: Systems and methods are provided for delivering neurostimulation therapies to patients for treating chronic heart failure. A neural fulcrum zone is identified and ongoing neurostimulation therapy is delivered within the neural fulcrum zone. This neural fulcrum zone corresponds to a combination of stimulation parameters at which autonomic engagement is achieved, while the tachycardia-inducing stimulation effects are offset by the bradycardia-inducing effects, thereby minimizing side effects such as significant heart rate changes while providing a therapeutic level of stimulation.Type: GrantFiled: July 30, 2021Date of Patent: August 29, 2023Assignees: LivaNova USA, Inc., East Tennessee State UniversityInventors: Bruce H. KenKnight, Jeffrey L. Ardell, Imad Libbus, Badri Amurthur
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Patent number: 11739757Abstract: A system may include a magnetic shape memory (MSM) element having a longitudinal axis that extends from a first end of the MSM element to a second end of the MSM element. The system may further include a rotatable permanent magnet configured to rotate around an axis of rotation and positioned proximate to the MSM element. The system may also include a first solenoid having a first solenoid axis directed at the rotatable permanent magnet. The system may include a second solenoid having a second solenoid axis directed at the rotatable permanent magnet. A method may include applying a first alternating current (AC) signal to the first solenoid and a second AC signal to the second solenoid to cause the rotatable permanent magnet to rotate.Type: GrantFiled: July 27, 2020Date of Patent: August 29, 2023Assignee: Boise State UniversityInventor: Peter Müllner
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Patent number: 11741643Abstract: A system for generating a 4D representation of a scene in motion given a sinogram collected from the scene while in motion. The system generates, based on scene parameters, an initial 3D representation of the scene indicating linear attenuation coefficients (LACs) of voxels of the scene. The system generates, based on motion parameters, a 4D motion field indicating motion of the scene. The system generates, based on the initial 3D representation and the 4D motion field, a 4D representation of the scene that is a sequence of 3D representations having LACs. The system generates a synthesized sinogram of the scene from the generated 4D representation. The system adjusts the scene parameters and the motion parameters based on differences between the collected sinogram and the synthesized sinogram. The processing is repeated until the differences satisfy a termination criterion.Type: GrantFiled: March 22, 2021Date of Patent: August 29, 2023Assignees: Lawrence Livermore National Security, LLC, Arizona Board of Regents on Behalf of Arizona State UniversityInventors: Hyojin Kim, Rushil Anirudh, Kyle Champley, Kadri Aditya Mohan, Albert William Reed, Suren Jayasuriya
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Patent number: 11742902Abstract: A communications network system is disclosed. The system may include a central processing unit (CPU) in data communication with a first access point (AP) configured to enable a data communication between the CPU and a first user equipment (UE). The CPU may include a processor configured to select a first group of APs including the first AP, establish a first data communications link over a first frequency band between the CPU and the first AP, cause the first AP to establish a second data communications link over a second frequency band between the first AP and the first UE, and transmit a portion of data to the first AP over the first data communications link. The first data communications link may be a wireless data communications link. The first frequency band may include higher frequency levels than those of the second frequency band.Type: GrantFiled: December 10, 2021Date of Patent: August 29, 2023Assignee: ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITYInventors: Ahmed Alkhateeb, Umut Demirhan
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Patent number: 11741196Abstract: A secure processor, comprising a logic execution unit configured to process data based on instructions; a communication interface unit, configured to transfer of the instructions and the data, and metadata tags accompanying respective instructions and data; a metadata processing unit, configured to enforce specific restrictions with respect to at least execution of instructions, access to resources, and manipulation of data, selectively dependent on the received metadata tags; and a control transfer processing unit, configured to validate a branch instruction execution and an entry point instruction of each control transfer, selectively dependent on the respective metadata tags.Type: GrantFiled: November 14, 2019Date of Patent: August 29, 2023Assignee: The Research Foundation for The State University of New YorkInventor: Kanad Ghose
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Patent number: 11738289Abstract: Techniques in the disclosure use non-wetting or wetting surfaces to promote or hinder separation of gas from solution in a liquid. The systems and processes promote bubble nucleation and/or promote separation of a gas or gases from a liquid using non-wetting surfaces. Also, the systems and processes suppress bubble nucleation in order to create supersaturated solutions of gas or gases in a liquid by using wetting surfaces.Type: GrantFiled: January 25, 2022Date of Patent: August 29, 2023Assignee: THE BOARD OF REGENTS FOR OKLAHOMA STATE UNIVERSITYInventor: Prem Kumar Bikkina
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Patent number: 11739337Abstract: Disclosed is a synthetic gene cluster for producing gadusol derivatives, expression vectors and host cells containing the same, methods of producing gadusol derivatives, and compositions thereof. In an example, the synthetic gene cluster includes a valA nucleotide sequence capable of expressing ValA protein; a nucleotide sequence capable of expressing methyltransferase/oxidoreductase (MT-Ox) protein; a mysC nucleotide sequence capable of expressing a MysC protein; and a mysD nucleotide sequence capable of expressing a MysD protein. In this way, gadusol derivatives can be produced in amounts sufficient for use in a variety of applications.Type: GrantFiled: September 4, 2020Date of Patent: August 29, 2023Assignee: OREGON STATE UNIVERSITYInventors: Taifo Mahmud, Andrew Robert Osborn
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Patent number: 11739314Abstract: Methods and compositions for multiplexed protein-protein interaction profiling (e.g., immunoprofiling), based on nucleic acid tagging of polypeptides (e.g., by RNA display) are described. In some embodiments the described compositions and methods utilize a library of prey polypeptide targets linked to prey RNAs encoding them, and a population of bait polypeptides, e.g., a mixture of antibodies, that bind to one or more of the prey polypeptide targets and are used to isolate and identify the bound prey polypeptide targets by amplification of their associated prey RNAs and sequencing of the corresponding cDNAs. In other embodiments the prey polypeptide targets are linked to DNA Bar Codes, which serve as unique identifiers of the tagged polypeptide.Type: GrantFiled: June 15, 2020Date of Patent: August 29, 2023Assignee: ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITYInventor: Joshua LaBaer
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Patent number: 11738300Abstract: A system and method for passive collection of atmospheric carbon dioxide is disclosed. The system includes a harvest chamber having a first opening and a sorbent regeneration system. The system also includes a capture body coupled to and movable by a support structure. The capture body includes a sorbent material and is movable by the support structure to be in a collection configuration wherein at least a portion of the capture body is in contact with a natural airflow outside the harvest chamber such that atmospheric carbon dioxide is captured by the sorbent material, and a release configuration wherein at least a portion of the capture body holding captured carbon dioxide is operated upon by the regeneration system inside the harvest chamber such that captured carbon dioxide is released to form an enriched gas.Type: GrantFiled: February 21, 2019Date of Patent: August 29, 2023Assignee: Arizona Board of Regents on behalf of Arizona State UniversityInventors: Klaus Lackner, Shreyans Kedia, Brinton Carlson, Robert Page, Venkatram Choodamani, Allen Wright
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Patent number: 11738098Abstract: Embodiments of the present disclosure provide for contrast agents, methods of making contrast agents, and methods of using contrast agents, and the like.Type: GrantFiled: October 12, 2020Date of Patent: August 29, 2023Assignee: Georgia State University Research Foundation, Inc.Inventors: Jenny Jie Yang, Zhiren Liu, Jie Jiang, Shenghui Xue, Jinjuan Qiao, Mani Salarian
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Patent number: 11739984Abstract: Various implementations include solar thermal energy collection system comprising a solar energy concentrator, a heat transfer fluid, an absorber pipe. The absorber pipe includes a pipe wall and has a central longitudinal axis. The pipe wall has an inner surface and an outer surface. The inner surface has a first contour defining alternating peaks and troughs along a length of the absorber pipe. The outer surface has a second contour defining alternating peaks and troughs along the length of the absorber pipe. The inner surface defines the entire flow path for the heat transfer fluid through the absorber pipe. The first contour, as viewed through an axial cross section of the absorber pipe, forms sinusoidal waves on each side of and spaced apart from the central longitudinal axis. The sinusoidal waves on each side of the central longitudinal axis are symmetrical with respect to the central longitudinal axis.Type: GrantFiled: March 31, 2021Date of Patent: August 29, 2023Assignee: The Florida State University Research Foundation, Inc.Inventors: Sam Yang, Juan Carlos Ordonez
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Patent number: 11742662Abstract: Technologies for controlling forced oscillations in electrical power grids include a processing unit and a phasor measurement unit and a control device coupled to a power grid. The processing unit receives a measurement indicative of active power in the power grid from the phasor measurement unit and determines a frequency of a forced oscillation active in the power grid based on the measurement. The processing unit injects a corrective signal with the control device into the power grid. The processing unit determines a corrective phase and a corrective amplitude in response to injecting the corrective signal. The processing unit continues to inject the corrective signal with the corrective phase and the corrective amplitude. The control device may be a static VAR compensator, a synchronous generator, a static synchronous compensator, a synchronous condenser, an electric storage device, or a solar power plant. Other embodiments are described and claimed.Type: GrantFiled: April 23, 2021Date of Patent: August 29, 2023Assignee: Washington State UniversityInventors: Vaithianathan Venkatasubramanian, Yuan Zhi, Habib Wajid
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Patent number: 11739047Abstract: The present invention provides a compound, and method of inhibiting the activity of a Fatty Acid Binding Protein (FABP) comprising contacting the FABP with a compound, said compound having the structure: Formula (I)Type: GrantFiled: February 11, 2021Date of Patent: August 29, 2023Assignee: THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORKInventors: Iwao Ojima, Dale Deutsch, Martin Kaczocha, Kongzhen Hu, Simon Tong, Matthew Elmes, Su Yan
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Publication number: 20230265311Abstract: The present invention relates to a resin composition comprising 20-70 wt % of an aromatic di(meth)acrylate component; 5-25 wt % of a flexible di(meth)acrylate component; and 10-70 wt % of a crosslinker component; wherein the resin composition further comprises: 0.1-10 phr initiator; 0-10 phr silica; and 5-50 phr milled carbon fiber. The invention also relates to a polymerized coating disposed over a substrate, the coating comprising 20-70 wt % aromatic di(meth)acrylate subunits; 5-25 wt % flexible di(meth)acrylate subunits; and 10-70 wt % crosslinker subunits; wherein the coating further comprises: 0.1-10 phr silica; and 5-50 phr milled carbon fiber. The invention also relates to a method of depositing a coating over a substrate, the method comprising the steps of: providing a resin composition; applying the resin composition over a substrate; and polymerizing the resin composition to form a solid coating.Type: ApplicationFiled: November 23, 2022Publication date: August 24, 2023Applicant: Board of Supervisors of Louisiana State University and Agricultural and Mechanical CollegeInventors: John Anthony Pojman, Daniel Paul Gary
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Publication number: 20230263587Abstract: Various systems, methods, and devices for identifying instrument movements likely to cause intraoperative bleeding are described. An example method includes identifying a movement of an instrument; determining that the movement of the instrument exceeds a threshold; and dampening the movement of the instrument based on determining that the movement exceeds the threshold.Type: ApplicationFiled: September 22, 2021Publication date: August 24, 2023Applicant: Wayne State UniversityInventors: Abhilash K. Pandya, Mostafa Daneshgar Rahbar, Luke A. Reisner, Hao Ying
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Publication number: 20230269377Abstract: A system defining a visual sensing pipeline architecture flexibly allows application developers to dynamically adapt the spatial resolution and update rate of different “rhythmic pixel encoding regions” in a scene. The system ingests pixel streams with raster-scan pixel read-out patterns, but only encodes relevant pixels prior to storing them in memory. The system includes streaming hardware to decode the stored rhythmic pixel encoding region stream into traditional frame-based representations to feed into standard computer vision algorithms.Type: ApplicationFiled: February 24, 2023Publication date: August 24, 2023Applicant: Arizona Board of Regents on Behalf of Arizona State UniversityInventors: Venkatesh Kodukula, Alexander Shearer, Van Nguyen, Srinivas Lingutla, Robert LiKamWa
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Publication number: 20230265041Abstract: This invention provides a compound having the structure wherein ?, ?, X, Y, and R1-R11 are defined herein. This invention also provides a pharmaceutical composition comprising the above compounds, a method of inhibiting the activity and/or levels of a matrix metalloproteinase (MMP), a method of inhibiting the production of a cytokine in a population of cells, a method of inhibiting the production of a growth factor in a population of cells, and a method of inhibiting NFK-B activation in a population of cells.Type: ApplicationFiled: February 27, 2023Publication date: August 24, 2023Applicants: The Research Foundation for the State University of New York, Chem-Master International, Inc.Inventors: Francis Johnson, Lorne Johnson
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Patent number: 11730697Abstract: A method of forming an ocular delivery device includes exposing a solid, shaped cellulose polymer to a solution including an active pharmaceutical ingredient (API) and a solvent capable of solubilizing the API, wherein the polymer absorbs at least a portion of the solution, including the API and solvent. The method may further include removing at least a portion of the absorbed solvent from the polymer by allowing the absorbed solvent to evaporate from the polymer or by drying the polymer. A variety of cellulose polymers may be used, including hydroxypropyl cellulose. A variety of APIs may be used, including Cyclosporine, Tobramycin and Vancomycin. Ocular delivery devices prepared by the methods may be used to treat a variety of eye disorders.Type: GrantFiled: January 7, 2019Date of Patent: August 22, 2023Assignees: Bausch Health Americas, Inc., Louisiana State University Agricultural and Mechanical CollegeInventors: Jean Theresa Jacob, Kevin John Halloran, Yuri McKee
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Patent number: 11733552Abstract: An optical device is disclosed. The optical device includes a silicon substrate, an aluminum oxide layer, an aluminum layer between the silicon substrate and the aluminum oxide layer, and a metasurface nanostructure. The metasurface nanostructure may include a graphene monolayer on the aluminum oxide layer and an electrically conductive nanoantenna array in direct contact with the graphene monolayer, where each nanoantenna in the nanoantenna array may include multiple segments, each segment having one or more parameters selected to achieve simultaneous resonance in the mid-infrared and the near infrared spectral regions when the graphene monolayer is irradiated with a near infrared pump pulse and a continuous mid-infrared probe. The optical device generates mid-infrared pulses via ultrafast modulation of hot carriers in the monolayer graphene.Type: GrantFiled: March 31, 2021Date of Patent: August 22, 2023Assignee: ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITYInventors: Yu Yao, Ali Basiri