Patents Assigned to State University
  • Method for monitoring bronchoscopic-based microwave ablation and related system
    Patent number: 11751943
    Abstract: A novel monitoring method evaluates tissue ablation progress. An antenna in a distal portion of an ablation applicator sends and receives electrical information from the target tissue during ablation. The information is used to determine ablation progress. A related ablation monitoring system includes a power monitor and processor operable to evaluate ablation progress based on reflected electrical properties during the ablation. The invention has particular benefits when used in endoscopic-based microwave ablation.
    Type: Grant
    Filed: January 26, 2018
    Date of Patent: September 12, 2023
    Assignee: State University Research
    Inventors: Punit Prakash, Austin Pfannenstiel
  • Evaporative cooling garment
    Patent number: 11751612
    Abstract: An evaporative cooling garment includes a first layer and a second layer superimposed over the first layer. The first layer is configured to absorb a quantity of water, and the second layer includes a reflective material and defines openings. The first layer is visible from an exterior of the garment through the openings in the second layer, and the garment defines a collapsible gap between an inner surface of the second layer and an outer surface of the first layer.
    Type: Grant
    Filed: January 15, 2021
    Date of Patent: September 12, 2023
    Assignee: Arizona Board of Regents on behalf of Arizona State University
    Inventor: Konrad Rykaczewski
  • Cas9 proteins and guiding features for DNA targeting and genome editing
    Patent number: 11753651
    Abstract: The present invention is directed to methods and compositions comprising novel CRISPR polypeptides and polynucleotides for site-specific cleavage and nicking of nucleic acids, transcriptional control and genome editing.
    Type: Grant
    Filed: September 6, 2019
    Date of Patent: September 12, 2023
    Assignee: North Carolina State University
    Inventors: Rodolphe Barrangou, Alexandra Briner Crawley
  • Mechanophore-grafted polymers to form stress-responsive thermoset network
    Patent number: 11753498
    Abstract: Compositions including a thermosetting polymer network and a mechanophore covalently bonded to the thermosetting polymer network are provided. Substrates including the compositions are provided. In addition, methods of making the compositions and methods of monitoring stress on a substrate comprising the compositions are provided.
    Type: Grant
    Filed: May 24, 2021
    Date of Patent: September 12, 2023
    Assignee: ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY
    Inventors: Lenore Dai, Aditi Chattopadhyay, Elizabeth Nofen, Jin Zou, Bonsung Koo
  • Targeting tumor cells with chemotherapeutic agents conjugated to anti-matriptase antibodies by in vivo cleavable linking moieties
    Patent number: 11752215
    Abstract: The present invention relates to anti-matriptase antibodies and immunoconjugates of anti-matriptase antibodies with cytotoxic agents and the use thereof for killing or inhibiting the growth of matriptase-expressing cancer cells, such as those of multiple myeloma and breast cancers. In particular, immunoconjugates comprising an anti-matriptase monoclonal antibody and anticancer agents such as auristatin, including monomethyl auristatin E (MMAE) and monomethyl auristatin F (MMAF) are introduced, which have potent antitumor activity in vivo. Moreover, importantly; there was no weight loss or other evidence of toxicity in the animals, indicating that no significant free drug was released into the circulation from the conjugate. The present invention also provides compositions comprising these new immunoconjugates and use of them for treatment of malignancies comprising cells that express matriptase.
    Type: Grant
    Filed: March 12, 2021
    Date of Patent: September 12, 2023
    Assignees: RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY, GEORGETOWN UNIVERSITY
    Inventors: Siang-Yo Lin, Joseph R. Bertino, Chen-Yong Lin, Zoltan Szekely
  • Targeted mutagenesis of tobacco berberine bridge enzyme-like nucleic acids
    Patent number: 11753649
    Abstract: The present invention relates to modifications of berberine bridge enzyme-like nucleic acids and their use in modulation of nicotine biosynthesis in plants.
    Type: Grant
    Filed: November 22, 2021
    Date of Patent: September 12, 2023
    Assignee: North Carolina State University
    Inventors: Ralph E. Dewey, Ramsey S. Lewis
  • Systems and methods for low-power gas monitoring
    Patent number: 11754521
    Abstract: Systems and methods of applying a prediction model to metal oxide sensors that change their electric resistances in response to surrounding gas concentrations for predicting equilibrium state resistance values of the sensors. The method includes heating a metal oxide sensor to for a predetermined period of time for the metal oxide sensor to interact with a surrounding gas; sampling transient resistance values of the metal oxide sensor to obtain sampled transient resistance values; determining an electrical resistance of the metal oxide sensor in a chemical equilibrium state of the interaction of the metal oxide sensor and the surrounding gas via applying a neural network; and determining a concentration level of the surrounding gas at the chemical equilibrium state by mapping the determined electrical resistance to a corresponding concentration level of the surrounding gas.
    Type: Grant
    Filed: March 2, 2021
    Date of Patent: September 12, 2023
    Assignee: Rutgers, The State University of New Jersey
    Inventors: Richard Martin, Richard Howard, Yanyong Zhang, Zhenhua Jia
  • Electrically conductive concrete composition and system design for resistive heating of pavements with low volume fractions of carbon microfiber
    Patent number: 11753337
    Abstract: The present application relates to a concrete pre-mix composition comprising a cementitious material and a plurality of conductive carbon microfibers mixed with said cementitious material, where said conductive carbon microfibers are present in the concrete pre-mix composition in an amount such that, when said concrete pre-mix composition is hydrated to form concrete and cured, the conductive carbon microfibers are dispersed in the cured concrete in an amount of 0.75% to 2.00% of total mass of the concrete. The present application further relates to a concrete composition, a method of producing an electrically conductive concrete composition, an electrically conductive cured concrete form, and a system for heating pavement.
    Type: Grant
    Filed: December 6, 2019
    Date of Patent: September 12, 2023
    Assignee: IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC.
    Inventors: Halil Ceylan, Alireza Sassani, Hesham Abdualla, Sunghwan Kim, Ali Arabzadeh, Peter C. Taylor, Kasthurirangan Gopalakrishnan
  • Movement Analysis and Feedback Systems, Applications, Devices, and Methods of Production Thereof
    Publication number: 20230277092
    Abstract: Contemplated systems for monitoring and analysis of human motion synthesis are disclosed herein that include: at least one garment configured to be worn by a user, at least one inertial sensor, wherein the at least one inertial sensor is integrated with or into the at least one garment, an information system, wherein the information system communicates with the at least one inertial sensor to produce a set of data, at least one musculorientation metric generated by the information system, and at least one performance report that is produced from the analysis of the at least one musculorientation metric.
    Type: Application
    Filed: February 28, 2023
    Publication date: September 7, 2023
    Applicant: The Trustees of the California State University
    Inventors: Emel Demircan, I-Hung Khoo, Elliot Recinos
  • SMART HEADPHONE SYSTEM AND METHOD
    Publication number: 20230283940
    Abstract: Various embodiments comprise systems, methods, architectures, mechanisms and apparatus providing a sensing platform wherein one or more headphone drivers are used as a versatile sensor to receive excitation signals therefrom indicative of direct or indirect pressures associated with the ear canal acoustically cooperating with the diaphragms operatively coupled to the drivers.
    Type: Application
    Filed: May 24, 2021
    Publication date: September 7, 2023
    Applicant: Rutgers, The State University of New Jersey
    Inventors: Xiaoran FAN, Richard HOWARD
  • DETERMINING COMMUNICATION WINDOWS
    Publication number: 20230283528
    Abstract: For determining a communication window is disclosed, a method generates a communication graph that includes backbone nodes, dummy nodes, data collection nodes, downlink nodes, crosslink send nodes, and crosslink receive nodes. The backbone nodes, the data collection nodes, the downlink nodes, the crosslink-transmit nodes, and the crosslink-receive nodes are connected by one of a homogenous edge between nodes of a same type and transition edges between nodes of a different type. The method determines access windows for downlink communications and crosslink communications using the communication graph. The method selects access windows based on a task graph generated from the communication graph. The method communicates from a given satellite within the selected access windows.
    Type: Application
    Filed: March 3, 2023
    Publication date: September 7, 2023
    Applicant: Utah State University Space Dynamics Laboratory
    Inventors: Skylar Cox, Justin Whitaker, John Humble, Greg Droge
  • SYSTEM AND METHOD FOR PASSIVE COLLECTION OF ATMOSPHERIC CARBON DIOXIDE WITH ENHANCED AIR FLOW
    Publication number: 20230277976
    Abstract: A carbon dioxide collection system having a release enclosure, a capture structure, and a chimney is disclosed. The release enclosure includes a sorbent regeneration system. The capture structure includes a sorbent material, and is movable between collection and release configurations. The chimney is shaped such that an airflow upward through the chimney is created. The chimney is positioned above the release enclosure such that the airflow passes through the capture structure while in the collection configuration. The collection configuration includes the capture structure being elevated above the release enclosure so the sorbent material is exposed to the airflow generated by the chimney, allowing the sorbent material to capture CO2 from the airflow.
    Type: Application
    Filed: March 3, 2023
    Publication date: September 7, 2023
    Applicant: ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY
    Inventors: Klaus Lackner, Kacie Niimoto, Robert Page
  • IDENTIFICATION OF ESTROGEN RECEPTOR POSITIVE (ER+) BREAST CANCERS THAT WILL NOT DEVELOP TAMOXIFEN RESISTANCE
    Publication number: 20230279502
    Abstract: Disclosed herein are methods of treating and identifying subjects with ER+ breast cancer that will or will not develop resistance of tamoxifen. In some examples such methods include measuring expression of adaptor-related protein complex 2, sigma-1 subunit (AP2S1) from the retrograde neurotrophin signaling pathway, cyclin-dependent kinase 2 (CDC2) from the loss of NLP from mitotic centrosomes pathway, general transcription factor IIIC subunit 3 (GTF3C3) from the RNA polymerase III transcription initiation from Type 2 promoter pathway, eukaryotic translation initiation factor 2-alpha kinase 3 (EIFA2AK3) from the EIF2 pathway, and leucyl-tRNA synthetase (LARS) from the valine, leucine and isoleucine biosynthesis pathway.
    Type: Application
    Filed: June 29, 2021
    Publication date: September 7, 2023
    Applicant: Rutgers, The State University of New Jersey
    Inventors: Antonina Mitrofanova, Sarra M. Rahem
  • LABEL-FREE QUANTIFICATION OF CELL SURFACE MEMBRANE PROTEIN BINDING KINETICS IN BIOLOGICAL SYSTEMS
    Publication number: 20230278032
    Abstract: Disclosed herein is a system and method for quantitative detection and analysis of molecular binding kinetics of a substance with surface membrane proteins of a biological object, such as a live cell, based on detecting and tracking membrane fluctuation amplitude changes cause by membrane displacement associated with the binding of the substance with the surface membrane proteins. The molecular binding kinetics can be detected with high precision in real time from an optical image of the biological object with a differential detection method.
    Type: Application
    Filed: February 24, 2023
    Publication date: September 7, 2023
    Applicant: ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY
    Inventors: Shaopeng WANG, Fenni ZHANG
  • BLOCKCHAIN-BASED VOTING SYSTEM
    Publication number: 20230282052
    Abstract: A control system for conducting an election may include a voter client configured to be used by a voter to cast a vote for a candidate, a registrar server, and a moderator server. The moderator server may be configured to obscure the identity of the voter. The registrar server may be configured to randomly assign a ballot to the obscured voter. The registrar server may be configured to encrypt the ballot. The moderator server may be configured to transmit the encrypted ballot to the voter client. The voter client may be configured to decrypt the encrypted ballot to recover the ballot. The voter client, in response to the voter selecting a desired candidate, may be configured to generate a ballot associated with a vote. The voter client may be configured to encrypt the ballot using a public key of the registrar server and a public key of the moderator server.
    Type: Application
    Filed: June 29, 2021
    Publication date: September 7, 2023
    Applicant: Board of Trustees of Michigan State University
    Inventors: Jian REN, Ehab ZAGHLOUL, Tongtong LI
  • Security-enhanced deep learning fingerprint-based indoor localization
    Patent number: 11751057
    Abstract: An exemplary radio fingerprint-based indoor localization method and system is disclosed that is resistant to spoofing or jamming attacks (e.g., at nearby radios, e.g., access points), among other types of interference. The exemplary method and system may be applied in the configuring of a secured convolutional neural network (S-CNNLOC) or secured deep neural network configured for attack-resistant fingerprint-based indoor localization.
    Type: Grant
    Filed: September 18, 2020
    Date of Patent: September 5, 2023
    Assignee: Colorado State University Research Foundation
    Inventors: Sudeep Pasricha, Saideep Tiku
  • Quantum dot porous silicon membrane-based radiation detector
    Patent number: 11749706
    Abstract: A detection layer (416) for a radiation detector (400) includes a porous silicon membrane (418). The porous silicon membrane includes silicon (419) with a first side (430) and a second opposing side (432), a plurality of pores (420) extending entirely through the silicon from the first side to the second opposing side, each including shared walls (426), at least one protrusion of silicon (424) protruding out and extending from the first side a distance (504, 604, 704). The porous silicon membrane further includes a plurality of radiation sensitive quantum dots (422) in the pores and a quantum dot layer disposed on the first side and having a surface (434) and a thickness (506, 606, 706), wherein the thickness is greater than the distance.
    Type: Grant
    Filed: March 16, 2020
    Date of Patent: September 5, 2023
    Assignees: KONINKLIJKE PHILIPS N.V., WAYNE STATE UNIVERSITY
    Inventors: Marc Anthony Chappo, Stephanie Lee Brock
  • Weapon and tool head and method
    Patent number: 11747118
    Abstract: The invention is directed to a weapon or tool head that has an appearance that mimics chipped stone weapon- or tool heads used in prehistory and history. The weapon or tool head has an outer body portion having the desired “ancient” appearance and a hard insert is provided with at least one sharp edge exposed for use, the latter providing modern performance characteristics to the weapon or tool.
    Type: Grant
    Filed: November 11, 2021
    Date of Patent: September 5, 2023
    Assignee: KENT STATE UNIVERSITY
    Inventors: Metin I. Eren, Michelle R. Bebber, Michael R. Fisch, Michael Kavulic, Trent A. W. True
  • Cancer treatment via repositioned tricyclic anti-depressant-like drugs as anti-cancer agents and new combinations of such drugs
    Patent number: 11744827
    Abstract: Methods and compositions for treating a lysosomal movement associated disease in an animal, in which the position of lysosomes can influence disease progression, comprising administering an effective amount of a first lysosome migration inhibitor or a pharmaceutically acceptable salt, solvate, clathrate, stereoisomer, enantiomer or prodrug thereof.
    Type: Grant
    Filed: June 29, 2020
    Date of Patent: September 5, 2023
    Assignee: Board of Supervisors of Louisiana State University and Agricultural and Mechanical College
    Inventors: James Allen Cardelli, Magdalena Liliana Circu, Samantha Sarah Dykes, Hazem Edmond El-Osta
  • Cell penetrating peptides that inhibit IRF5 nuclear localization
    Patent number: 11746133
    Abstract: Inhibitors of interferon regulatory factor 5 (IRF5) nuclear localization and methods of using the inhibitors to treat autoimmune diseases such as systemic lupus erythematosus (SLE) are described.
    Type: Grant
    Filed: September 13, 2021
    Date of Patent: September 5, 2023
    Assignee: Rutgers, The State University of New Jersey
    Inventor: Betsy J. Barnes