Patents Assigned to STC.UNM
  • Patent number: 10464985
    Abstract: The present invention is directed to novel non-invasive diagnostic tools/compounds to image cancers, especially, melanoma, including metastatic melanoma in vivo. The present compounds exhibit enhanced uptake in cancerous cells and tissue and decreased renal uptake in kidney, evidencing favorable pharmacokinetics of compounds of the present invention. The compounds according to the present invention represent an advance in the diagnosis and treatment of melanoma, including metastatic melanoma using non-invasive molecular imaging techniques. The novel probes of the present invention are also useful for initiating therapy for melanoma as well as monitor patients' response to chemotherapy treatments and other interventions or therapies used in the treatment of melanoma/metastatic melanoma. Compounds according to the present invention may be used as diagnostic tools for a number of conditions and diseases states as well as therapeutic agents for treating such conditions and disease states.
    Type: Grant
    Filed: July 19, 2018
    Date of Patent: November 5, 2019
    Assignee: STC.UNM
    Inventors: Yubin Miao, Haixun Guo
  • Patent number: 10466326
    Abstract: A method of measuring the concentration of a magnetic material in an object using magnetic resonance imaging comprising administering magnetic material to the object; obtaining a set of T1-weighted and T2-weighted images of the object in order to determine a background magnetic resonance imaging signal intensity and measurements of the background nuclear magnetic relaxation times (T1, T2) of the object without magnetic material; and obtaining a set of T1-weighted and T2-weighted magnetic resonance images of the object with magnetic materials added; measuring effect of magnetic material on the relaxation times; and converting the T1-weighted and T2-weighted images into a set of contrast images which are subtracted from each other to yield a contrast difference image proportional to the concentration of the magnetic material.
    Type: Grant
    Filed: May 13, 2016
    Date of Patent: November 5, 2019
    Assignee: STC. UNM
    Inventor: Laurel Sillerud
  • Patent number: 10453996
    Abstract: A method of forming a semiconductor structure includes providing a substrate comprising a first material portion and a single crystal silicon layer on the first material portion. The substrate further comprises a major front surface, a major backside surface opposing the major front surface, and a plurality of grooves positioned in the major front surface. A buffer layer is deposited in one or more of the plurality of grooves. A semiconductor material is epitaxially grown over the buffer layer and in the one or more plurality of grooves, the epitaxially grown semiconductor material comprising a hexagonal crystalline phase layer and a cubic crystalline phase structure disposed over the hexagonal crystalline phase.
    Type: Grant
    Filed: December 9, 2016
    Date of Patent: October 22, 2019
    Assignee: STC.UNM
    Inventors: Steven R. J. Brueck, Seung-Chang Lee, Christian Wetzel, Mark Durniak
  • Patent number: 10442934
    Abstract: A method and precursor for making carbon fibers and the like comprising carbon black modified with at least one cyclic compound promoter. A source of the carbon black may be recycled materials such as recycled tires or recycled plastics. The carbon black is modified by attaching at least one cyclic compound promoter to the outer periphery of the carbon black.
    Type: Grant
    Filed: December 18, 2015
    Date of Patent: October 15, 2019
    Assignee: STC.UNM
    Inventors: Richard Alan Kemp, Mahmoud Reda Taha
  • Patent number: 10436570
    Abstract: The present invention provides a Michelson interferometer for capturing images of a vibrating sample comprising a coherent light source. The light source may be adapted to illuminate a sample with a constant brightness across the sample. The interferometer may also be configured to generate a 3D representation of a sample using a single frame for a predetermined phase of the sample. The 3D representations may be combined to create a 3D video representation of the vibrating sample.
    Type: Grant
    Filed: November 7, 2016
    Date of Patent: October 8, 2019
    Assignee: STC.UNM
    Inventors: Arash Kheyraddini-Mousavi, Zayd Leseman, Behnam Kheyraddini-Mousavi
  • Publication number: 20190298222
    Abstract: An apparatus for determining a position of an object inside a body includes a first detector configured to receive a signal from the object inside the body. The apparatus also includes a camera configured to capture an image or video of outside of a portion of the body. The object is positioned inside the portion of the body. A connoting system is configured to receive the signal from the first detector and the image or video from the camera and to determine the position of the object inside the body. A screen is configured to display die position of the object inside the body.
    Type: Application
    Filed: December 7, 2017
    Publication date: October 3, 2019
    Applicant: STC.UNM
    Inventors: Sang M. HAN, Jarred Caldwell, Nicholas BRECHTEL, Nathan MADRID, Divya PRAKASH
  • Publication number: 20190292579
    Abstract: Methods and apparatus for rapid, culture free pathogen detection. The methods utilize optical spectroscopy techniques to identify and/or characterize pathogens in a sample via the detection of unique properties and/or analytes that are specific to particular pathogens.
    Type: Application
    Filed: September 18, 2017
    Publication date: September 26, 2019
    Applicant: STC.UNM
    Inventors: Aaron Kurt Neumann, Matthew S Graus, Jerilyn A Timlin
  • Patent number: 10408673
    Abstract: A 2-D sensor array includes a semiconductor substrate and a plurality of pixels disposed on the semiconductor substrate. Each pixel includes a coupling region and a junction region, and a slab waveguide structure disposed on the semiconductor substrate and extending from the coupling region to the region. The slab waveguide includes a confinement layer disposed between a first cladding layer and a second cladding layer. The first cladding and the second cladding each have a refractive index that is lower than a refractive index of the confinement layer. Each pixel also includes a coupling structure disposed in the coupling region and within the slab waveguide. The coupling structure includes two materials having different indices of refraction arranged as a grating defined by a grating period. The junction region comprises a p-n junction in communication with electrical contacts for biasing and collection of carriers resulting from absorption of incident radiation.
    Type: Grant
    Filed: September 15, 2017
    Date of Patent: September 10, 2019
    Assignee: STC.UNM
    Inventors: Steven R. J. Brueck, Alexander Neumann, Payman Zarkesh-Ha
  • Publication number: 20190265166
    Abstract: Methods and apparatus for rapid, culture and/or label free pathogen detection. The methods utilize optical spectroscopy techniques to identify and/or characterize pathogens in a sample via the detection of unique properties and/or analytes that are specific to particular pathogens.
    Type: Application
    Filed: September 18, 2017
    Publication date: August 29, 2019
    Applicant: STC.UNM
    Inventors: Aaron Kurt Neumann, Anatoliy O Pinchuk, Ke Jiang
  • Patent number: 10389745
    Abstract: Bots are detected real-time by correlating activity between users using a lag-sensitive hashing technique that captures warping-invariant correlation. Correlated users groups in social media may be found that represent bot behavior with thousands of bot accounts detected in a couple of hours.
    Type: Grant
    Filed: August 4, 2016
    Date of Patent: August 20, 2019
    Assignee: STC.UNM
    Inventors: Abdullah Mueen, Nikan Chavoshi
  • Patent number: 10381737
    Abstract: The present invention provides an antenna miniaturized topology that is based on the implementation of a conductive loading on a quadrifilar helix antenna. This may be achieved by connecting the tip of the four helical arms to end members which may be circular planar conductors. The miniaturization of the antenna may be further enhanced by incorporating a dielectric material in the space between the four arms.
    Type: Grant
    Filed: September 15, 2017
    Date of Patent: August 13, 2019
    Assignee: STC.UNM
    Inventors: Youssef Antoine Tawk, Christos G. Christodoulou, Joseph Costantine, Michel Chahoud, Marwan Fadous
  • Patent number: 10370305
    Abstract: The present invention concerns compositions and methods of using the same that provide encapsulated polymer nanocomposites for efficient crack repair and monitoring of a cement-substrate interface.
    Type: Grant
    Filed: August 21, 2017
    Date of Patent: August 6, 2019
    Assignee: STC.UNM
    Inventors: Mahmoud Reda Taha, John Stormont, Edward N. Matteo
  • Patent number: 10366253
    Abstract: A Hardware-Embedded Delay Physical Unclonable Function (“HELP PUF”) leverages entropy by monitoring path stability and measuring path delays from core logic macros. Reliability and security enhancing techniques for the HELP PUF reduce bit flip errors during regeneration of the bitstring across environmental variations and improve cryptographic strength along with the corresponding difficulty of carrying out model building attacks. A voltage-based enrollment process screens unstable paths on normally synthesized (glitchy) functional units and reduces bit flip errors by carrying out enrollment at multiple supply voltages controlled using on-chip voltage regulators.
    Type: Grant
    Filed: December 15, 2015
    Date of Patent: July 30, 2019
    Assignee: STC.UNM
    Inventor: James Plusquellic
  • Publication number: 20190227050
    Abstract: Methods and apparatus for long read, label-free, optical nanopore long chain molecule sequencing. In general, the present disclosure describes a novel sequencing technology based on the integration of nanochannels to deliver single long-chain molecules with widely spaced (>wavelength), ˜1-nm aperture “tortuous” nanopores that slow translocation sufficiently to provide massively parallel, single base resolution using optical techniques. A novel, directed self-assembly nanofabrication scheme using simple colloidal nanoparticles is used to form the nanopore arrays atop nanochannels that unfold the long chain molecules. At the surface of the nanoparticle array, strongly localized electromagnetic fields in engineered plasmonic/polaritonic structures allow for single base resolution using optical techniques.
    Type: Application
    Filed: December 10, 2018
    Publication date: July 25, 2019
    Applicant: STC.UNM
    Inventors: Steven R.J. Brueck, Jeremy Scott Edwards, Alexander Neumann, Yuliya Kuznetsova, Edgar A. Mendoza
  • Patent number: 10345486
    Abstract: The present invention is an apparatus and method of forecasting solar energy irradiance potential and subsequent photovoltaic output in a region. The apparatus and method includes collecting meteorological data for a given region and then estimating irradiance levels using parameters collected from the meteorological data. Solar energy production is then simulated using the collected meteorological data, estimated irradiance levels, and physical characteristics of a solar generating system in the given region at a predetermined time.
    Type: Grant
    Filed: January 22, 2018
    Date of Patent: July 9, 2019
    Assignee: STC.UNM
    Inventors: Anthony Robert Menicucci, Thomas P. Caudell, Andrea A. Mammoli
  • Patent number: 10337186
    Abstract: The present invention provides a fiber reinforced polymer composite having a plurality of layers containing a plurality of fibers. The layers may be configured to maintain predetermined load sharing ratios among the layers at different load levels to produce a gradual load transfer between the different layers during the progressive failure of the composite. The composite is comprised of mono-fibers and the load sharing ratios of the layers have coefficients of variation that are less than 20%.
    Type: Grant
    Filed: November 20, 2015
    Date of Patent: July 2, 2019
    Assignee: STC.UNM
    Inventors: Mahmoud Reda Taha, Eslam Mohamed Soliman
  • Patent number: 10329614
    Abstract: This disclosure describes, in one aspect, methods for DNA sequencing and performing epigenomic analyses. Generally, the methods include immobilizing a plurality of copies of a DNA molecule on a surface, stretching at least a portion of the immobilized DNA molecules, and sequencing at least a portion of the immobilized, stretched DNA molecules.
    Type: Grant
    Filed: August 1, 2014
    Date of Patent: June 25, 2019
    Assignee: STC.UNM
    Inventor: Jeremy Scott Edwards
  • Patent number: 10320149
    Abstract: The invention concerns a wavelength tunable semiconductor laser comprising a laser gain section (510) optically coupled to an underlying optical waveguide (520). According to an embodiment of the invention, a first and a second passive microring resonators (530, 560) having a whistle geometry, are arranged on both sides of the laser gain section and evanescently coupled with the optical waveguide (520). Highly reflective broadband mirrors (541, 571) are provided at the free ends of optical waveguide branches (240, 270) tangentially connected to the microring resonators. The first and second passive microrings resonators provide an optical feedback to the laser gain section and allow to select the desired wavelength. The laser structure can be implemented according to a III-V/Si technology.
    Type: Grant
    Filed: June 29, 2016
    Date of Patent: June 11, 2019
    Assignee: STC.UNM
    Inventors: Marek Osinski, Frédéric Grillot
  • Patent number: 10317212
    Abstract: Apparatus, systems, and methods associated with enhancement of phase response of intracavity phase interferometers are applicable in a variety of applications.
    Type: Grant
    Filed: May 18, 2018
    Date of Patent: June 11, 2019
    Assignee: STC.UNM
    Inventors: Jean-Claude Diels, Ladan Arissian, Matthias Lenzner, James Hendrie
  • Publication number: 20190169583
    Abstract: A novel peptide sequence that is a modified derivative of a neuron-specific tyrosine phosphatase is shown and described. Specifically, the novel peptide sequence is a modified derivative of striatal-enriched tyrosine phosphatase (STEP). The peptide sequence has been modified so as to be able to ameliorate and treat brain injury resulting from excessive glutamate release and/or oxidative stress. Examples of the types of brain injury which the presently disclosed peptide sequence is useful for treating includes acute brain injury resulting from stroke or traumatic brain injury and chronic disorders such as Huntington's chorea and schizophrenia. Furthermore, the presently described peptide sequence may further be useful in the treatment and amelioration of disorders associated with fear memory such as post-traumatic stress disorder.
    Type: Application
    Filed: August 29, 2018
    Publication date: June 6, 2019
    Applicant: STC.UNM
    Inventor: Surojit Paul