Patents Assigned to Stellenbosch University
-
Patent number: 9700883Abstract: A polymeric compound is provided having the general formula (A) wherein R is an alkyl chain preferably having from 1 to 6 carbon atoms in the chain which may be either saturated or unsaturated and may have substituents attached to the chain, and R? and R?, which may be the same or different from each other and preferably have from 1 to 4 carbon atoms in a chain, are selected from alkyl groups, substituted or unsubstituted, or R? and R? are linked to form a saturated or unsaturated cyclic moiety incorporating the adjacent nitrogen atom, with or without additional heteroatoms in the ring. The polymeric compound is preferably in a particulate form and most particularly in the form of nanoparticles. A method of producing the polymers is disclosed. A method of adsorbing, separating and stripping the polymers is also disclosed.Type: GrantFiled: January 20, 2012Date of Patent: July 11, 2017Assignee: STELLENBOSCH UNIVERSITYInventors: Lubertus Klumperman, Klaus Robert Koch, Eugene Marlin Lakay
-
Patent number: 9595034Abstract: A system and method for monitoring third party access to a restricted item is provided. Key data is embedded in the restricted item, the key data being associated with a store of value and usable to conduct a transaction against the store of value. A record of the transaction becomes visible in a transaction ledger. The transaction ledger is monitored to determine whether a transaction against the store of value has occurred, and the restricted item is designated as accessed by a third party in the event that a transaction against the store of value has occurred.Type: GrantFiled: May 22, 2014Date of Patent: March 14, 2017Assignee: STELLENBOSCH UNIVERSITYInventors: Gert-Jan Van Rooyen, Frederick Johannes Lutz, Herman Arnold Engelbrecht
-
Publication number: 20170023557Abstract: A system and method for the detection and quantification of biomolecules by measuring a piezoelectric signal is described. The system comprises a plurality of elongate zinc oxide nanowires mounted generally parallel to each another on a semi conductive silicon substrate. The free ends of the nanowires are provided with biomolecules that are capable of associating with complementary biomolecules within a biological or water sample. Following incubation of the system in a sample, the association of molecules of interest with the immobilised biomolecules on the system results in the displacement of the zinc oxide nanowires. The displacement of the nanowires produces a piezoelectric voltage signal that is useful in diagnosing a pathogenic infection or the contamination of a sample.Type: ApplicationFiled: November 3, 2014Publication date: January 26, 2017Applicant: Stellenbosch UniversityInventors: Leon Milner Theodore Dicks, Willem Jacobus Perold, Deon Nevwling, Thomas Stanley Van Den Heever
-
Patent number: 9543815Abstract: The invention relates to an electrical energy conversion system (11) which is particularly suited for use in wind energy conversion systems. The system includes two magnetically separated permanent magnet machines (25, 27) linked by a freely rotating rotor (19) housing permanent magnets (39). The first machine is typically a synchronous generator, and the second an induction generator. The synchronous generator (25) has a stationary stator (21) which is connectable to an electrical system such as an electricity grid, and the induction generator (27) has a rotor (17) which is connectable to a mechanical drive system such as, for example, a wind turbine.Type: GrantFiled: August 4, 2011Date of Patent: January 10, 2017Assignee: Stellenbosch UniversityInventors: Maarten Jan Kamper, Johannes Hendrik Jacob Potgieter, Johan Nico Stander
-
Patent number: 9512448Abstract: The present invention relates to methods for improving a host cell's ability to utilize the disaccharide cellobiose. In some embodiments, a transformed cell expresses intracellular ?-glucosidase. In other embodiments, a transformed host cell is able to grow on media wherein cellobiose is the sole carbon source. In other embodiments, selection methods are provided which improve a host cell's ability to grow on cellobiose-containing media.Type: GrantFiled: May 9, 2008Date of Patent: December 6, 2016Assignee: Stellenbosch UniversityInventors: Willem Van Zyl, Ronel Van Rooyen, Shaunita Hellouise Rose
-
Publication number: 20160336656Abstract: A multi-mode composite antenna is disclosed. The antenna includes at least two dipole elements, each dipole element having two arms with a signal transmission line connected to each arm, a conductive tube in which the signal transmission lines extend which forms a shield for the signal transmission lines, and an extension of the conductive tube. In one embodiment, the extension is formed by the conductive tube being folded back over itself. The dipole elements are capable of being excited by at least one differential mode excitation to realize a dipole radiation pattern, and the extension forms a monopole element with a monopole radiation pattern when at least one dipole element is excited by a common mode excitation. The composite antenna is capable of a combined monopole and dipole radiation pattern through the application of both differential mode excitation and common mode excitation.Type: ApplicationFiled: January 15, 2015Publication date: November 17, 2016Applicant: Stellenbosch UniversityInventors: David Schalk Van der Merwe Prinsloo, Petrie Meyer, Rob Maaskant, Marianna Valerievna Ivashina
-
Publication number: 20160330988Abstract: The invention provides protein-functionalised magnetic nanoparticles comprising magnetic nanoparticles (MNPs) to which a lactose-binding protein or enzyme has been immobilized. The protein-functionalised magnetic nanoparticles are particularly suitable for separating lactose from a lactose-containing solution, such as milk, cheese, yoghurt, flavoured milk or the like. The protein-functionalised MNPs can be added to the lactose-containing solution and be allowed to bind to the lactose in the solution. The MNPs, to which the lactose is bound, can then be magnetically removed from the solution, e.g. by applying an external magnetic field.Type: ApplicationFiled: January 27, 2015Publication date: November 17, 2016Applicant: Stellenbosch UniversityInventors: Amanda Jane Dodd, Lubertus Klumperman, Pieter Swart
-
Patent number: 9490542Abstract: A multi-mode composite antenna is disclosed. The antenna includes at least two dipole elements, each dipole element having two arms with a signal transmission line connected to each arm, a conductive tube in which the signal transmission lines extend which forms a shield for the signal transmission lines, and an extension of the conductive tube. In one embodiment, the extension is formed by the conductive tube being folded back over itself. The dipole elements are capable of being excited by at least one differential mode excitation to realize a dipole radiation pattern, and the extension forms a monopole element with a monopole radiation pattern when at least one dipole element is excited by a common mode excitation. The composite antenna is capable of a combined monopole and dipole radiation pattern through the application of both differential mode excitation and common mode excitation.Type: GrantFiled: January 15, 2015Date of Patent: November 8, 2016Assignee: Stellenbosch UniversityInventors: David Schalk Van der Merwe Prinsloo, Petrie Meyer, Rob Maaskant, Marianna Valerievna Ivashina
-
Publication number: 20160298804Abstract: A height adjustable pylon and supporting frame assembly is provided. The frame includes two frame members meeting at a corner with the frame members being generally co-planar and the pylon being urged into the corner so as to extend at generally right angles to a plane including the two frame members. A fastener assembly has two end portions each anchored relative its associated frame member so as to extend transversely to it. The fastener assembly includes an intermediate saddle portion engaging a surface of the pylon that is directed outwardly relative to the corner with the pylon being urged into the corner when the fastener assembly is tightened to engage the pylon and lock it axially relative to the frame members in a selected position. Preferably, the frame members each form two upper and two lower frame members of two trusses. Lower ends of the pylons may support the assembly.Type: ApplicationFiled: April 7, 2016Publication date: October 13, 2016Applicant: STELLENBOSCH UNIVERSITYInventors: Willem Adolph Landman, James Nicholas Larmuth
-
Publication number: 20160298354Abstract: A supporting frame includes a truss composed of an upper straight frame member and a parallel lower straight frame member supported at their ends in spaced relationship relative to each other. At least two spans of divergent inclined brace member extend between them with the ends of the brace member spans each being securable to the upper or lower straight frame member by means of a fastener. Limited relative longitudinal movement of the upper and lower straight frame members is permitted before a fastener is secured to fix the positions at which the ends of the brace member spans are attached to the upper and lower straight frame members. In one application two trusses meet at a corner with a pylon being urged in the plane of the supporting frame into a corner between two frame members of each pair of trusses to extend at right angles to the frame.Type: ApplicationFiled: April 7, 2016Publication date: October 13, 2016Applicant: STELLENBOSCH UNIVERSITYInventor: Paul Gauché
-
Patent number: 9447398Abstract: The present invention provides for heterologous expression of polypeptides encoded by wild-type and codon-optimized cbh2 genes from the organisms Cochliobolus heterostrophus, Gibberella zeae, Irpex lacteus, Volvariella volvacea, and Piromyces sp. in host cells, such as the yeast Saccharomyces cerevisiae. The expression in such host cells of the corresponding genes, and variants and combinations thereof, result in improved specific activity of the expressed cellobiohydrolases. Thus, such genes and expression systems are useful for efficient and cost-effective consolidated bioprocessing systems.Type: GrantFiled: October 25, 2010Date of Patent: September 20, 2016Assignee: Stellenbosch UniversityInventors: Riaan Den Haan, Emile Van Zyl
-
Patent number: 9389030Abstract: A splash grid is provided for installation in a rain zone of liquid gas contacting industrial equipment. The splash grid has a supporting frame assembly and multiple generally parallel elongate elements supported by the frame assembly. The elongate elements each has a transverse dimension, in plan view, not exceeding 3 mm, and a spacing in plan view not exceeding 10 mm. The elongate elements may be of a molded plastic material that is optionally integral with a surround that forms, or is attached to, the supporting frame assembly. Alternatively, the elongate elements may be separately manufactured flexible filament or cord supported by a surround that forms or is attached to the supporting frame assembly. The elongate elements may be staggered in the vertical direction and gaps may be provided for larger objects to pass through the splash grid. A liquid cooling installation having a rain zone fitted with a splash grid is also provided.Type: GrantFiled: July 10, 2012Date of Patent: July 12, 2016Assignee: STELLENBOSCH UNIVERSITYInventors: Hanno Carl Rudolf Reuter, Detlev Gustav Kröger
-
Patent number: 9365842Abstract: The present invention provides for heterologous expression of polypeptides encoded by wild-type and codon-optimized variants of cbh1 and/or cbh2 from the fungal organisms Talaromyces emersonii (T. emersonii), Humicola grisea (H. grisea), Thermoascus aurantiacus (T. aurantiacus), and Trichoderma reesei (T. reesei) in host cells, such as the yeast Saccharomyces cerevisiae. The expression in such host cells of the corresponding genes, and variants and combinations thereof, result in improved specific activity of the expressed cellobiohydrolases. Thus, such genes and expression systems are useful for efficient and cost-effective consolidated bioprocessing systems.Type: GrantFiled: May 11, 2009Date of Patent: June 14, 2016Assignee: Stellenbosch UniversityInventors: Riaan Den Haan, Emile Van Zyl, Danie Lagrange
-
Patent number: 9315833Abstract: The present invention relates to the engineering and expression of heterologous cellulosomes in microorganisms in order to facilitate the conversion of biomass to useful products. In some embodiments, the invention relates to the expression of scaffoldin proteins which form the nucleus of a cellulosome. Cellulases or other biomass-degrading enzymes can be non-covalently linked to the scaffoldin protein by virtue of a dockerin domain-cohesin domain interaction.Type: GrantFiled: February 18, 2010Date of Patent: April 19, 2016Assignees: Lallemand Hungary Liquidity Management LLC, Stellenbosch UniversityInventors: John McBride, Mark Mellon, Vineet Rajgarhia, Elena E. Brevnova, Erin Wiswall, David A. Hogsett, Danie LaGrange, Shaunita Rose, Emile Van Zyl
-
Publication number: 20160069910Abstract: A method and a detection device for detecting endocrine disrupting compounds are provided. The detection device includes a support structure and ligand binding domains (LBD) of at least one sex hormone receptor, immobilised on the support structure. The detection device further includes a linker molecule between the support structure and the ligand binding domains, for immobilising the LBD's on the support structure.Type: ApplicationFiled: November 4, 2015Publication date: March 10, 2016Applicant: STELLENBOSCH UNIVERSITYInventors: Pieter SWART, Barry Eric TRUEBODY
-
Patent number: 9243256Abstract: The invention relates to the combination of the TLG1 glucoamylase from Thermomyces lanuginoses with: (i) the SFA1 alpha-amylase from Saccharomycopsis fibuligera; and/or (ii) the LKA alpha-amylase. The enzyme combinations may be expressed in a host cell (e.g. in Saccharomyces cerevisiae) or provided as an enzyme composition. Methods for making the enzyme combinations of the invention are provided. The invention also relates to a yeast strain which exhibits amylolytic activity and promising fermentative abilities. Processes for producing a fermentation product (in particular alcohol) from starch-containing material are described.Type: GrantFiled: April 12, 2010Date of Patent: January 26, 2016Assignees: Stellenbosch University, Universita Degli Studi Di PadovaInventors: Willem Heber Van Zyl, Tania Jooste, Johann Ferdinand Gorgens, Maryna Saayman, Lorenzo Favaro, Marina Basaglia, Sergio Casella
-
Patent number: 9206444Abstract: The present invention is directed to a yeast strain, or strains, secreting a full suite, or any subset of that full suite, of enzymes to hydrolyze corn starch, corn fiber, lignocellulose, (including enzymes that hydrolyze linkages in cellulose, hemicellulose, and between lignin and carbohydrates) and to utilize pentose sugars (xylose and arabinose). The invention is also directed to the set of proteins that are well expressed in yeast for each category of enzymatic activity. The resulting strain, or strains can be used to hydrolyze starch and cellulose simultaneously. The resulting strain, or strains can be also metabolically engineered to produce less glycerol and uptake acetate. The resulting strain, or strains can also be used to produce ethanol from granular starch without liquefaction.Type: GrantFiled: February 12, 2014Date of Patent: December 8, 2015Assignees: Lallemand Hungary Liquidity Management LLC, Stellenbosch UniversityInventors: Elena Brevnova, John E. McBride, Erin Wiswall, Kevin S. Wenger, Nicky Caiazza, Heidi Hau, Aaron Argyros, Frank Agbogbo, Charles F. Rice, Trisha Barrett, John S. Bardsley, Abigail Foster, Anne K. Warner, Mark Mellon, Ryan Skinner, Indraneel Shikhare, Riaan Den Haan, Chhayal V. Gandhi, Alan Belcher, Vineet B. Rajgarhia, Allan C. Froehlich, Kristen M. Deleault, Emily Stonehouse, Shital A. Tripathi, Jennifer Gosselin, Yin-Ying Chiu, Haowen Xu
-
Patent number: 9205453Abstract: A method and apparatus provided for the production of fine fibers by electrospinning fibers by applying an electrical field between a primary electrode and a counter electrode (5) spaced apart from the primary electrode and extending generally parallel thereto wherein at least an operative surface of the primary electrode is coated with a polymer solution (3) and an electric field of sufficient magnitude is generated between the primary electrode and counter electrode to cause the formation of fine fibers (9) in the space between the electrodes. The operative surface of the primary electrode that is coated with polymer solution is made up of appropriate portions of the surfaces of a multitude of operatively semi-submerged, loose (unattached) elements (1, 11, 17, 21) supported on the bottom of a trough (2) or tray or another support member or members (12, 18, 22).Type: GrantFiled: June 11, 2014Date of Patent: December 8, 2015Assignee: Stellenbosch UniversityInventors: Anton Eugene Smit, Ronald Douglas Sanderson
-
Publication number: 20150324764Abstract: A system and method of enabling a user to transact using cryptocurrency of a value defined in relation to a different medium of exchange or financial instrument is provided. In the method, a request to create a voucher having a face value remaining defined in relation to the medium of exchange or financial instrument is received. A voucher having key data being associated with a voucher cryptocurrency address holding a token amount of cryptocurrency included therein is generated. A transaction ledger is monitored to determine whether a redeeming transaction against the voucher address has occurred against a destination cryptocurrency address. Responsive to a redeeming transaction against the voucher address occurring, an additional amount of cryptocurrency is transferred to the destination address. The additional amount of cryptocurrency being calculated such that the sum of the token and additional amounts substantially matches a cryptocurrency equivalent of the face value of the voucher.Type: ApplicationFiled: May 6, 2015Publication date: November 12, 2015Applicant: STELLENBOSCH UNIVERSITYInventors: Gert-Jan VAN ROOYEN, Herman Arnold ENGELBRECHT, Helghardt AVENANT, Michail BRYNARD
-
Publication number: 20150303767Abstract: A machine having two co-axial and relatively rotatable rotors and a coaxial stator or housing with respect to which both rotors are rotatable is provided wherein two bearing arrangements mutually support the two rotors with respect to each other and with respect to the stator or housing. One of the bearing arrangements comprises multiple support bearings angularly spaced apart with respect to the axis of rotation of the rotors relative to the stator with the support bearings each having an axle or shaft that is fixed relative to one of the rotors or the stator. Each support bearing cooperates with a raceway provided on a concentric adjacent rotor or stator. The machine may be an electromechanical machine such as a wind turbine in which rotational movement of one of the rotors relative to the other and relative to the stator generates electrical energy.Type: ApplicationFiled: November 15, 2013Publication date: October 22, 2015Applicant: STELLENBOSCH UNIVERSITYInventor: Johan Nico STANDER