Patents Assigned to StemCell Technologies Inc.
  • Patent number: 6645727
    Abstract: The present invention relates to antibody composition that are useful in preparing enriched mesenchymal progenitor cell preparations. The invention also relates to kits for carrying out the processes and to the cell preparations prepared by the processes.
    Type: Grant
    Filed: May 25, 2001
    Date of Patent: November 11, 2003
    Assignee: StemCell Technologies Inc.
    Inventors: Terry Thomas, Emer Clarke
  • Publication number: 20030185817
    Abstract: The present invention relates to methods for separating cells using immunorosettes. The method involves contacting a sample containing nucleated cells and red blood cells with an antibody composition which allows immunorosettes of the nucleated cells and the red blood cells to form. The antibody composition preferably contains bifunctional antibodies or tetrameric antibody complexes.
    Type: Application
    Filed: December 6, 2002
    Publication date: October 2, 2003
    Applicant: StemCell Technologies Inc.
    Inventors: Terry E. Thomas, Carrie E. Peters, Peter M. Lansdorp
  • Publication number: 20030147886
    Abstract: The present invention relates to antibody composition that are useful in preparing enriched cell preparations such as human hematopoietic progenitor cells and stem cells and non-hematopoietic tumor cells. The invention also relates to kits for carrying out the processes and to the cell preparations prepared by the processes.
    Type: Application
    Filed: October 8, 2002
    Publication date: August 7, 2003
    Applicant: StemCell Technologies Inc.
    Inventors: Terry Thomas, Peter Lansdorp
  • Publication number: 20030092078
    Abstract: The present invention relates to methods for separating cells using immunorosettes. The method involves contacting a sample containing nucleated cells and red blood cells with an antibody composition which allows immunorosettes of the nucleated cells and the red blood cells to form. The antibody composition preferably contains bifunctional antibodies or tetrameric antibody complexes.
    Type: Application
    Filed: July 12, 2002
    Publication date: May 15, 2003
    Applicant: StemCell Technologies Inc.
    Inventors: Terry E. Thomas, Carrie Peters, Peter Lansdorp
  • Patent number: 6491917
    Abstract: The present invention relates to an antibody composition which contains antibodies specific for glycophorin A, CD2, CD3, CD14, CD15, CD16, CD19, CD24, CD56, CD66b and IgE antigens. A negative selection process is also provided for use on blood and bone marrow samples from a patient with chronic myeloid leukemia to recover cell preparations depleted of lineage committed cells. The invention also relates to kits for carrying out this process and to the cell preparations prepared by the process.
    Type: Grant
    Filed: July 30, 1999
    Date of Patent: December 10, 2002
    Assignee: StemCell Technologies Inc.
    Inventors: Terry E. Thomas, Connie J. Eaves
  • Patent number: 6491918
    Abstract: The present invention relates to antibody composition that are useful in preparing enriched cell preparations such as human hematopoietic progenitor cells and stem cells and non-hematopoietic tumor cells. The invention also relates to kits for carrying out the processes and to the cell preparations prepared by the processes.
    Type: Grant
    Filed: October 28, 1999
    Date of Patent: December 10, 2002
    Assignee: StemCell Technologies Inc.
    Inventors: Terry Thomas, Peter Lansdorp
  • Publication number: 20020177176
    Abstract: The present invention relates to an antibody composition which contains antibodies directed to murine leukocyte and murine erythroid cells. This composition is used in a novel negative selection process to enrich for human hematopoietic cells from a sample from human-murine chimeric mice. The invention also relates to kits for carrying out this process.
    Type: Application
    Filed: May 20, 2002
    Publication date: November 28, 2002
    Applicant: STEMCELL TECHNOLOGIES INC.
    Inventors: Terry E. Thomas, Connie J. Eaves
  • Patent number: 6482926
    Abstract: The present invention relates to antibody composition that are useful in preparing enriched cell preparations such as human hematopoietic progenitor cells and stem cells and non-hematopoietic tumor cells. The invention also relates to kits for carrying out the processes and to the cell preparations prepared by the processes.
    Type: Grant
    Filed: March 22, 2000
    Date of Patent: November 19, 2002
    Assignee: StemCell Technologies Inc.
    Inventors: Terry Thomas, Peter Lansdorp
  • Patent number: 6448075
    Abstract: The present invention relates to methods for separating cells using immunorosettes. The method involves contacting a sample containing nucleated cells and red blood cells with an antibody composition which allows immunorosettes of the nucleated cells and the red blood cells to form. The antibody composition preferably contains bifunctional antibodies or tetrameric antibody complexes.
    Type: Grant
    Filed: May 26, 2000
    Date of Patent: September 10, 2002
    Assignee: StemCell Technologies Inc.
    Inventors: Terry E. Thomas, Carrie Peters, Peter Lansdorp
  • Patent number: 6342344
    Abstract: The present invention relates to an antibody composition which contains antibodies directed to murine leukocyte and murine erythroid cells. This composition is used in a novel negative selection process to enrich for human hematopoietic cells from a sample from human-murine chimeric mice. The invention also relates to kits for carrying out this process.
    Type: Grant
    Filed: July 30, 1999
    Date of Patent: January 29, 2002
    Assignee: StemCell Technologies Inc.
    Inventors: Terry E. Thomas, Connie J. Eaves
  • Patent number: 6306575
    Abstract: The present invention relates to an antibody composition which contains antibodies specific for glycophorin A, CD3, CD24, CD16, CD14, and optionally CD45RA, CD38, CD36, CD38, CD56, CD2, CD19, CD66e, CD66b, and/or antibodies specific for antigens expressed on non-hematopoietic tumor cells. A process is also provided for enriching and recovering human hematopoietic progenitor cells and stem cells in a sample containing human hematopoietic differentiated, progenitor, and stem cells, and optionally tumor cells.
    Type: Grant
    Filed: December 1, 1995
    Date of Patent: October 23, 2001
    Assignee: StemCell Technologies, Inc.
    Inventors: Terry Thomas, Peter Lansdorp
  • Patent number: 6117985
    Abstract: The present invention relates to antibody composition that are useful in preparing enriched cell preparations such as human hematopoietic progenitor cells and stem cells and non-hematopoietic tumor cells. The invention also relates to kits for carrying out the processes and to the cell preparations prepared by the processes.
    Type: Grant
    Filed: June 1, 1998
    Date of Patent: September 12, 2000
    Assignee: Stemcell Technologies Inc.
    Inventors: Terry Thomas, Peter Lansdorp
  • Patent number: 5877299
    Abstract: The present invention relates to an antibody composition which contains antibodies specific for glycophorin A, CD3, CD24, CD16, CD14, and optionally CD45RA, CD36, CD56, CD2, CD19, CD66a and/or CD66b. A process is also provided for enriching and recovering human hematopoietic progenitor cells and stem cells in a sample containing human hematopoietic differentiated, progenitor, and stem cells. The process involves reacting the sample with an antibody composition containing antibodies capable of binding to the antigens glycophorin A, CD3, CD24, CD16, and CD14, and optionally CD45RA, CD36, CD56, CD2, CD19, CD66a and/or CD66b under conditions so that cell conjugates are formed between the antibodies and differentiated cells having the antigens glycophorin A, CD3, CD24, CD16, and CD14, and optionally CD45RA, CD36, CD56, CD2, CD19, CD66a and/or CD66b on their surfaces. The cell conjugates are removed and a cell preparation is obtained which is enriched in human hematopoietic progenitor cells and stem cells.
    Type: Grant
    Filed: June 16, 1995
    Date of Patent: March 2, 1999
    Assignee: Stemcell Technologies Inc.
    Inventors: Terry Thomas, Peter Lansdorp
  • Patent number: D490531
    Type: Grant
    Filed: November 22, 2002
    Date of Patent: May 25, 2004
    Assignee: StemCell Technologies Inc.
    Inventor: Alex Feldman