Abstract: Copolymers having improved machining and water resistant properties are produced using a monomer containing an adduct protecting group, particularly an alkyl boronic acid adduct, of glyceryl acrylate or glyceryl methacrylate, in combination with an alkyl acrylate or methacrylate, and optionally a glycidyl acrylate or methacrylate. After machining and shaping, the adduct is removed to provide a hydrogel useful as a contact lens material.

Abstract: An implanting device for implanting pellets and like subcutaneously or intramuscularly in animals is described which utilizes means for indexing an implant magazine having a plurality of pellet-containing stations therein and means for automatically retracting a needle from about an implant charge to deposit the pellets in an animal. The implant magazine is indexed for sequential applications automatically as the retraction mechanism is cocked. Additionally, means for automatically ejecting a spent or empty implant cartridge are provided to prevent false deposition of implants. An implant cartridge having open channels containing implants can be utilized with the implanting device, the channels having means thereon for increasing the size of the channel during the implanting step to substantially eliminate the crushing or breaking of pellets as they are expelled from the cartridge. Alignment and stabilization means for the implant magazine and the implanting device also are provided.

Abstract: A fluid actuated brake assembly for use with a parallelogram linkage on a dental tray support arm is described. Floating brake shoes positioned on opposite sides of one member of the parallelogram linkage with one of the brake shoes pivotably and slideably attached to the other member of the parallelogram linkage provides a braking and locking effect between the two members of the parallelogram linkage to provide an efficient brake for a dental tray support arm. Upon fluid actuation of the brake assembly, the brake shoes grip one member of the parallelogram and form a rigid connection with the other member of the parallelogram to prevent relative movement of the parallelogram linkage members. The frictional brake assembly also provides an override feature above a predetermined force level to prevent accidental jamming of the dental tray support arm against an object.

Abstract: Compounds of the formula:R'--CH.sub.2 --S--Awherein:R' is hydrogen, alkyl, --COOH or its pharmaceutically acceptable salts, --alkylene--COOH or its pharmaceutically acceptable salts, --alkylene-SO.sub.2 H or its pharmaceutically acceptable salts, --alkylene-SO.sub.3 H or its pharmaceutically acceptable salts, or --alkylene CH.sub.2 OH; andA is the acyl moiety of a pharmaceutically acceptable carboxylic acid, said acid having antiinflammatory properties;are gastrointestinal tract sparing drugs for antiinflammatory pharmaceuticals.

Abstract: Racemic mixtures of d,1-2-(6-methoxy-2-naphthyl)propanal are resolved by forming a condensation product with N-R-D-glucamine or a salt thereof where R is hydrogen, alkyl of 1 to 36 carbon atoms or cycloalkyl of 3 to 8 carbon atoms, from which a product substantially enriched in d-2-(6-methoxy-2-naphthyl)propanal can be obtained and then can be selectively oxidized to d-2-(6-methoxy-2-naphthyl)propionic acid.

Abstract: The availability of supplemental dietary choline to animals with a developed rumen is increased by co-administering choline or choline compounds with a propionate-enhancing antibiotic compound.

Abstract: A method of contraception and a pharmaceutical package for effecting the method are disclosed. The method comprises a three phase sequence of estrogen/progestogen administration which is a daily sequence of unit dosages over a repeating cycle, which dosage sequence comprises, for one cycle:(a) administering, as phase one, about 20-40 .mu.g of ethinyl estradiol, (or of other estrogen in an amount sufficient to result in an equivalent effect) and about 0.3-0.8 mg of norethindrone (or of other progestogen in an amount sufficient to result in an equivalent effect) each day for 5-8 days, followed by;(b) administering, as phase two, the same dosage of estrogen and twice the dosage of progestogen each day as was administered each day in phase one, for 7-11 days, followed by;(c) administering, as phase three, the same dosage of estrogen and the same dosage of progestogen each day as was administered each day in phase one, for 3-7 days, followed by;(d) administering, as phase four, no therapeutically active dosage, i.

Abstract: The mixture of polyethylene glycol having a molecular weight of about 380 to about 630 with the prostaglandins dl-9.alpha.,11.alpha.,15.alpha.-trihydroxy-16-phenoxy-17,18,19,20-tetranor prosta-4,5,13-trans-trieneoic acid and the lower alkyl esters thereof are useful for parenteral administration to mammals as luteolytic agent, primarily for inducing abortion.

Abstract: A method of conditioning diesel engines is described. In accordance with the method, a diesel engine is operated on a diesel fuel containing from about 20-30 ppm of dicyclopentadienyl iron or an equivalent amount of a derivative thereof for a period of time sufficient to eliminate carbon deposits from the combustion surfaces of the engine and to deposit a layer of iron oxide on the combustion surfaces, which layer is effective to prevent further buildup of carbon deposits, and subsequently the diesel engine is operated on a maintenance concentration of from about 10-15 ppm of dicyclopentadienyl iron or an equivalent amount of a derivative thereof on a continuous basis. The maintenance concentration is effective to maintain the catalytic iron oxide layer on the combustion surfaces but insufficient to decrease timing delay in the engine.

Abstract: A solution for removing occluded and adsorbed chemicals, such as cationic preservating agents, anionic preserving agents and mixtures thereof, from contact lenses which comprises a nonionic surfactant; a cationic ion exchange resin, an anionic ion exchange resin, or mixtures thereof; water; and optionally sodium chloride. Such solutions are useful to reduce and prevent irritation of the eye of the contact lens wearer.

Abstract: Pharmaceutically acceptable acid addition salts of sulfur containing antimicrobial 1-substituted imidazole compounds can be stabilized in talc-based powders by the addition of a basic metal salt of an inorganic or organic acid.

Abstract: The invention provides new hydrogel forming materials comprising synthetic, hydrophilic, aqueous-insoluble polymer networks formed by copolymerization of a hydrophilic dihydroxyalkyl acrylate or methacrylate, a substantially water insoluble alkyl acrylate or methacrylate, one or more additional hydrophilic comonomers selected from the group of vinylic monomers, acrylates, and methacrylates, and a cross-linking agent. The hydrogels are preferably used for the formation of contact lenses, but may also be used for drug and pesticides delivery devices; dialysis, ultrafiltration and reverse osmosis membranes; implants in surgery and dentistry; and the like.

Abstract: A dental instrument is disclosed having a light source assembly suspension which includes resilient means, such as a coil spring, for supporting the lamp assembly while at the same time reducing vibration that may be transmitted from the instrument to the light source assembly. The resilient means also reduces heat loss from the light source assembly to the dental instrument so that shorter filament warm-up time is provided. The light source assembly suspension is particularly useful in a dental handpiece in which the frequency of vibration of the gas-driven motor may coincide with one of the harmonic frequencies of vibration of the lamp filament or filament support.

Abstract: Compounds useful as antifungal, antibacterial and antiprotozoal agents are represented by the formula: ##STR1## wherein: Z is oxygen or sulfur;R.sup.1 is phenyl optionally substituted with one or more substituents selected from the group consisting of halo, lower alkyl of one to four carbon atoms, lower alkoxy of one to four carbon atoms and trifluoromethyl;R.sup.2 is phenyl or benzyl wherein the phenyl ring of R.sup.2 is optionally substituted by one or more substituents selected from the group consisting of halo, lower alkyl of one to four carbon atoms, lower alkoxy of one to four carbon atoms and trifluoromethyl; or by a phenyl optionally substituted by halo, lower alkyl of one to four carbon atoms, lower alkoxy of one to four carbon atoms or trifluoromethyl; andthe antimicrobial acid addition salts thereof.

Abstract: A gel formulation, which is inherently spermicidal and which provides an efficient delivery system for spermicidal and other contraceptively effective compounds intravaginally is disclosed. Said formulation is useful in methods of intravaginal contraception.

Abstract: A reversible cam lock assembly is described. The cam lock assembly is adapted for attachment to a movable member and includes an eccentric cam for engaging a surface of a stationary member to resist movement inducing forces applied to the movable member. Depending on the orientation of the cam lock assembly, clockwise or counterclockwise rotational movement of the movable member relative to the stationary member is resisted.

Abstract: Compounds of the formula: ##STR1## wherein R.sub.1 is phenyl optionally substituted with one or more substituents independently selected from the group consisting of lower alkyl, lower alkoxy, halo, or trifluoromethyl;Z is ethylene or propylene, optionally substituted with a single substituent which is lower alkyl;A is the integer 0, 1, 2, or 3;B is the integer 1, 2, or 3; andwherein the sum of A and B is 1, 2, 3 or 4; andthe pharmaceutically acceptable acid addition salts thereof, said compounds being useful as spermicidal, antimicrobial and anticonvulsant agents.

Abstract: Degradation of prostaglandins in anhydrous or aqueous pharmaceutically acceptable, water-miscible alcohol solutions is prevented by adding a stabilizing amount of a pharmaceutically acceptable acetal.