Patents Assigned to Syracuse University
  • System and method for controlling growth of microorganisms with brominated furanones
    Patent number: 8530680
    Abstract: A method for inhibiting the growth of a microorganism using an effective amount of one or more of the following synthetic brominated furanones: (i) 4-bromo-5Z-(bromomethylene)-3-methylfuran-2-one; (ii) 3-(dibromomethyl)-5-(dibromomethylene)furan-2-one; (iii) 3-(bromomethyl)-5-(dibromomethylene)furan-2-one; (iv) 4-bromo-3-(bromomethyl)-5Z-(bromomethylene)furan-2-one; or (v) 4-bromo-5-(dibromomethyl)-3-methylfuran-2(5H)-one. The brominated furanones inhibit the growth of both fungi and bacteria, including the fungal species Candida albicans, Gloeophyllum trabeum, Chaetomium globosum, and Trametes versicolor and the bacterial species Pseudomonas aeruginosa. The brominated furanones can be used topically or internally to treat human infections, and can be used to treat other objects, such as wood building supplies, to prevent fungal rot.
    Type: Grant
    Filed: June 21, 2012
    Date of Patent: September 10, 2013
    Assignee: Syracuse University
    Inventors: Dacheng Ren, Yan Yeung Luk
  • System and method for controlling growth of microorganisms with brominated furanones
    Patent number: 8519166
    Abstract: A method for inhibiting the growth of a microorganism using an effective amount of one or more of the following synthetic brominated furanones: (i) 4-bromo-5Z-(bromomethylene)-3-methylfuran-2-one; (ii) 3-(dibromomethyl)-5-(dibromomethylene)furan-2-one; (iii) 3-(bromomethyl)-5-(dibromomethylene)furan-2-one; (iv) 4-bromo-3-(bromomethyl)-5Z-(bromomethylene)furan-2-one; or (v) 4-bromo-5-(dibromomethyl)-3-methylfuran-2(5H)-one. The brominated furanones inhibit the growth of both fungi and bacteria, including the fungal species Candida albicans, Gloeophyllum trabeum, Chaetomium globosum, and Trametes versicolor and the bacterial species Pseudomonas aeruginosa. The brominated furanones can be used topically or internally to treat human infections, and can be used to treat other objects, such as wood building supplies, to prevent fungal rot.
    Type: Grant
    Filed: November 13, 2009
    Date of Patent: August 27, 2013
    Assignee: Syracuse University
    Inventors: Dacheng Ren, Yan Yeung Luk
  • METHOD FOR INHIBITING THE FORMATION OF SET1 FAMILY CORE COMPLEXES
    Publication number: 20130203167
    Abstract: Disclosed in this specification is a method for inhibiting the formation of vertebrate SET1 family core complexes. A guanidinium-containing molecule is used to competitively inhibit the binding of the N-SET region of a SET1 protein to WDR5, thus inhibiting the formation of the SET1 family core complex. The guanidinium-containing molecule may be, for example, an arginine-containing peptide.
    Type: Application
    Filed: March 8, 2012
    Publication date: August 8, 2013
    Applicant: Syracuse University
    Inventors: Michael S. Cosgrove, Anamika Patel
  • WOVEN HYDROGEL BASED BIOSENSOR
    Publication number: 20130196309
    Abstract: A porous hydrogel sensor that is responsive to the presence of one or more target compounds in solution is synthesized based on demixing of certain molecules in the presence of a target compound. The porous hydrogel sensor may include fluorescently tagged antibodies that are noncovalently bound to the gel and then released in the presence of the target antigen. The porous hydrogel sensor may alternatively include dissolvable cross-links using polymerized antibody and antigen complexes so that, in the presence of the target antigen, the cross-links will be displaced and the hydrogel will dissolve.
    Type: Application
    Filed: January 31, 2013
    Publication date: August 1, 2013
    Applicant: SYRACUSE UNIVERSITY
    Inventor: Syracuse University
  • Bicyclic Furanones with Low Toxicity for Microbial Control
    Publication number: 20130197077
    Abstract: A class of bicyclic brominated furanone structures that have reduced toxicity and high activity for inhibiting biofilm formation and quorum sensing by microbes. The molecules have two fused cyclic alkyl groups that provide a structural framework that retain one or more bromine groups on the structure. The bicyclic furanones have reduced toxicity to mammalian cells as compared to other brominated furanones but retain the ability to inhibit biofilm formation in bacterial populations.
    Type: Application
    Filed: January 25, 2013
    Publication date: August 1, 2013
    Applicant: SYRACUSE UNIVERSITY
    Inventor: Syracuse University
  • INTRINSIC OXIDE BUFFER LAYERS FOR SOLAR CELLS
    Publication number: 20130167933
    Abstract: A method of, and apparatus for, increasing the power output of the cell using one or more intrinsic oxide buffer layers to reduce extraneous optical absorption. The intrinsic oxide buffer layers can be, for example: (i) an undoped oxide film that is prepared without intentional doping, (ii) a compensated oxide layer that is prepared using compensating dopants to reduce the conductivity of the oxide film, which can be either undoped or doped, and/or (iii) a passivated oxide layer that is prepared using hydrogen or other atoms to improve the electronic properties of low conductivity oxide films.
    Type: Application
    Filed: December 26, 2012
    Publication date: July 4, 2013
    Applicant: SYRACUSE UNIVERSITY
    Inventor: Syracuse University
  • AUTOMATIC DETECTION BY A WEARABLE CAMERA
    Publication number: 20130128051
    Abstract: There is set forth herein a system including a camera device. In one embodiment the system is operative to perform image processing for detection of an event involving a human subject. There is set forth herein in one embodiment, a camera equipped system employed for fall detection.
    Type: Application
    Filed: November 16, 2012
    Publication date: May 23, 2013
    Applicant: SYRACUSE UNIVERSITY
    Inventor: SYRACUSE UNIVERSITY
  • Antimicrobial nanostructured hydrogel web containing silver
    Patent number: 8431151
    Abstract: Robust polymeric hydrogels and a method to fabricate antimicrobial non-woven fibrous wound dressing with controlled silver release that may be used for anti-infective medical implants and anti-infective coating for implantable medical device. The hydrogels may be provided in non-woven fibrous wound dressing and anti-infective implantable medical devices, especially for reconstructive oral and bone surgery.
    Type: Grant
    Filed: August 6, 2010
    Date of Patent: April 30, 2013
    Assignee: Syracuse University
    Inventors: Patrick Mather, Jian Wu, Dacheng Ren, Shuyu Hou
  • Active cell culture via shape memory
    Patent number: 8404484
    Abstract: Substrates for cell culture and tissue engineering bioreactors consisting of polymers that change their shape over time under stimulation by temperature change, hydration, degradation, or other means. A method of controlling cell culture using a biodegradable shape memory polymer, wherein shape changes can transfer stresses, strains, or both to adherent or otherwise connected cells such that the mechanical stimulus impacts cell development and the resulting properties of tissues.
    Type: Grant
    Filed: July 15, 2010
    Date of Patent: March 26, 2013
    Assignee: Syracuse University
    Inventors: Patrick Mather, James Henderson, Kelly Burke, Kevin Davis, Xiuling Xu
  • System and method for the release of nitric oxide using nanoscale media
    Patent number: 8394393
    Abstract: A composite material containing polymeric nanofibers, themselves containing NO-donor molecules, imbibed with an elastomer matrix is permeable to both water and gas so that dissociation reactions in the presence of water releases NO gas in a sustained manner. The NO-donor nanofibers may be formed by synthesizing acceptable NO-donor molecules, blending such molecules in solution with PVP, PCL or PVAc, electrospinning the blend at relatively high voltage for form fiber mats, applying PDMS rubber to the fiber mat and crosslinking it. The resulting NO-releasing electrospun fiber composite may be used in medical devices such as catheters, stents, or vascular grafts, with the purpose of releasing nitric oxide within a controlled rate and for a sustained period of time, as well as other known medical applications for NO.
    Type: Grant
    Filed: April 6, 2011
    Date of Patent: March 12, 2013
    Assignee: Syracuse University
    Inventors: Patrick Mather, Ifeanyi Onyejewke, Kazuki Ishida
  • Active access control system and method
    Patent number: 8387115
    Abstract: A method of dynamically assigning a role to a user in a distributed computing environment can comprise the steps of: defining one or more roles and their respective threshold trust values; defining one or more attributes and their respective weight coefficients; determining current values of the attributes for the user; calculating a current level of trust for the user, based on the attribute values and the weight coefficients; and assigning a role to the user based on the current level of trust and the threshold values.
    Type: Grant
    Filed: February 18, 2009
    Date of Patent: February 26, 2013
    Assignee: Syracuse University
    Inventor: Joon S. Park
  • Multi-solution bone cements and methods of making the same
    Patent number: 8383734
    Abstract: The present invention relates to bone cements and, more particularly, to acrylic-based orthopedic bone cements, their use in spinal applications, and methods for making the same. An embodiment of the present invention provides a method of grafting PMMA brushes on cross-linked PMMA nanospheres comprising at least one of the following steps: performing a hydrolysis reaction of surface methyl ester groups of said cross-linked PMMA nanospheres to form surface carboxylic acid groups of said cross-linked PMMA nanospheres; forming a 2-aminoethyl acrylate compound; coupling said surface carboxylic acid groups of said cross-linked PMMA nanospheres with said 2-aminoethyl acrylate compound to form a coupled compound with an initiating site; and grafting said PMMA brushes onto said initiating site.
    Type: Grant
    Filed: April 21, 2010
    Date of Patent: February 26, 2013
    Assignee: Syracuse University
    Inventors: Julie M. Hasenwinkel, Jeremy L. Gilbert, Danieli C. Rodrigues, Rebecca Bader
  • SYSTEM AND METHOD FOR DISTRIBUTED AUDIO RECORDING AND COLLABORATIVE MIXING
    Publication number: 20130039496
    Abstract: Two or more wireless devices can be independently controlled by their respective users, a mixer component, or a leader wireless device to perform audio recording, convert the recorded audio into a standard or proprietary audio stream format, and transmit the audio stream to a server. The real-time clocks of two or more participating wireless devices can be synchronized. A wireless device can insert timestamps into the audio stream to facilitate the mixing operation. Mixing of the two or more audio streams recorded by wireless devices can be performed by a mixer component either in real time (contemporaneously with the recording) or asynchronously with respect to the recording. The mixing can be performed in a fully automated mode, and/or in an operator-assisted mode.
    Type: Application
    Filed: October 15, 2012
    Publication date: February 14, 2013
    Applicant: SYRACUSE UNIVERSITY
    Inventors: David Grandinetti, James Howison, Ian Molloy
  • High Performance Flame Fuel Cell Using an Anode Supported Solid-Oxide Fuel Cell
    Publication number: 20130011768
    Abstract: The present invention relates to an anode supported solid-oxide fuel cell based flame fuel cell that enable the generation of both electricity and heat from a flame (i.e. flame is used as a heat source and a fuel source for the fuel cell's operation, while supplying a useful heat for other thermochemical systems) and, more particularly, to an anode supported solid-oxide fuel cell based flame fuel cell that uses hydrocarbon/air mixture as a fuel source and includes a catalyst layer that can act as a protective layer for the anode layer, an anode layer, a cathode layer, an electrolyte layer, and an interlayer between the cathode layer and the electrolyte layer.
    Type: Application
    Filed: June 29, 2012
    Publication date: January 10, 2013
    Applicant: SYRACUSE UNIVERSITY
    Inventor: Jeongmin Ahn
  • SITUATION AWARE SECURITY SYSTEM AND METHOD FOR MOBILE DEVICES
    Publication number: 20120309354
    Abstract: A mobile communication device can comprise a microprocessor, a memory, and one or more sensors, all coupled to a system bus. A sensor can be provided by a GPS receiving device, an accelerometer, an image sensor, a radio frequency transceiver, or a magnetic card reading device. The mobile communication device can be configured, responsive to receiving sensor data from one or more sensors, to select a corresponding security alert level. The mobile communication device can be further configured to perform at least one security-related action corresponding to the selected security alert level.
    Type: Application
    Filed: November 17, 2011
    Publication date: December 6, 2012
    Applicant: SYRACUSE UNIVERSITY
    Inventor: Wenliang Du
  • NANOPARTICLE ARRAY COMPRISING DISTRIBUTED NANOPARTICLES
    Publication number: 20120292579
    Abstract: There is set forth herein a method for providing a nanoparticle array. A nanoparticle network can be provided by nanoparticles combined with surfactant micelle chains. The nanoparticle network can be provided by distributing metal nanoparticles in a surfactant solution and agitating the surfactant solution comprising the nanoparticles to form a gel comprising the nanoparticle network which can be characterized by a distributed array of nanoparticles combined with surfactant micelle chains within a fluid. The gel can comprise a fluid in a continuous phase and the nanoparticles in a discontinuous phase. Apparatus having arrays of nanoparticles are also set forth herein.
    Type: Application
    Filed: March 16, 2012
    Publication date: November 22, 2012
    Applicant: SYRACUSE UNIVERSITY
    Inventors: Radhakrishna Sureshkumar, Tao Cong, Satvik Wani
  • POLYSIALIC ACID-BASED N-TRIMETHYL CHITOSAN GEL NANOPARTICLES FOR SYSTEMIC DRUG DELIVERY
    Publication number: 20120294904
    Abstract: Gel nanoparticles for encapsulating and delivering a pharmaceutical compound to a patient. The nanoparticles are formed from N-trimethyl chitosan and polysialic acid, preferably in the presence of sodium tripolyphosphate. A ratio of polysialic acid to N-trimethyl chitosan of about 0.5 to 1 produces nanoparticles having diameter of about 100 nm (plus or minus 25 nm) and a zero potential above 30 milivolts that can stability contain a pharmaceutical compound, such as methotrexate, for delivery to a patient.
    Type: Application
    Filed: May 18, 2012
    Publication date: November 22, 2012
    Applicant: SYRACUSE UNIVERSITY
    Inventors: Rebecca A. Bader, Nan Zhang
  • Methods of Improving Detectors and Classifiers Using Optimized Stochastic Resonance Noise
    Publication number: 20120278039
    Abstract: Apparatus and method for improving the performance of a threshold-based detector or classifier, or a generic detector or classifier and increasing the probability of detecting at least one object in an image using novel algorithms and stochastic resonance noise is provided, where a suitable dose of noise is introduced to the image data such that the performance of the above-referenced detectors or classifiers is improved without altering the detector's or classifier's parameters. Several stochastic resonance (SR) noise-based detection and classification enhancement schemes are presented. The SR noise-enhanced detection and classification schemes can improve any algorithms and systems. To implement these schemes, the only knowledge that is needed is the original input data (no matter 1D, 2D, 3D or others) and the output (detection results) of the existing algorithms and systems.
    Type: Application
    Filed: March 2, 2012
    Publication date: November 1, 2012
    Applicant: SYRACUSE UNIVERSITY
    Inventors: Renbin Peng, Pramod K. Varshney
  • System and method for distributed audio recording and collaborative mixing
    Patent number: 8301076
    Abstract: Two or more wireless devices can be independently controlled by their respective users, a mixer component, or a leader wireless device to perform audio recording, convert the recorded audio into a standard or proprietary audio stream format, and transmit the audio stream to a server. The real-time clocks of two or more participating wireless devices can be synchronized. A wireless device can insert timestamps into the audio stream to facilitate the mixing operation. Mixing of the two or more audio streams recorded by wireless devices can be performed by a mixer component either in real time (contemporaneously with the recording) or asynchronously with respect to the recording. The mixing can be performed in a fully automated mode, and/or in an operator-assisted mode.
    Type: Grant
    Filed: August 19, 2008
    Date of Patent: October 30, 2012
    Assignee: Syracuse University
    Inventors: David Grandinetti, James Howison, Ian Molloy
  • SYSTEM AND METHOD FOR CONTROLLING GROWTH OF MICROORGANISMS WITH BROMINATED FURANONES
    Publication number: 20120264950
    Abstract: A method for inhibiting the growth of a microorganism using an effective amount of one or more of the following synthetic brominated furanones: (i) 4-bromo-5Z-(bromomethylene)-3-methylfuran-2-one; (ii) 3-(dibromomethyl)-5-(dibromomethylene)furan-2-one; (iii) 3-(bromomethyl)-5-(dibromomethylene)furan-2-one; (iv) 4-bromo-3-(bromomethyl)-5Z-(bromomethylene)furan-2-one; or (v) 4-bromo-5-(dibromomethyl)-3-methylfuran-2(5H)-one. The brominated furanones inhibit the growth of both fungi and bacteria, including the fungal species Candida albicans, Gloeophyllum trabeum, Chaetomium globosum, and Trametes versicolor and the bacterial species Pseudomonas aeruginosa. The brominated furanones can be used topically or internally to treat human infections, and can be used to treat other objects, such as wood building supplies, to prevent fungal rot.
    Type: Application
    Filed: June 21, 2012
    Publication date: October 18, 2012
    Applicant: SYRACUSE UNIVERSITY
    Inventors: Yan-Yeung Luk, Dacheng Ren