Patents Assigned to Sysmex Corporation
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Publication number: 20230078290Abstract: The ion sensor of the present invention is a current measurement type ion sensor that measures a current to measure a target ion, and includes an organic phase retaining layer containing an organic phase capable of forming an interface with the sample containing the target ion, a first electrode to which the organic phase retaining layer is laminated and containing a first insertion material composed of an inorganic compound, a second electrode arranged so as to face the organic phase holding layer and in contact with the sample.Type: ApplicationFiled: August 25, 2022Publication date: March 16, 2023Applicants: SYSMEX CORPORATION, NATIONAL UNIVERSITY CORPORATION KYOTO INSTITUTE OF TECHNOLOGYInventors: Junko KOJIMA, Kenichi UCHIYAMA, Yumi YOSHIDA
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Patent number: 11604201Abstract: Disclosed is a specimen analyzer configured to perform analysis on a specimen for a plurality of measurement items, the specimen analyzer including a measurement section configured to perform a specimen measurement for measuring a measurement sample prepared from a specimen and a reagent corresponding to a measurement item, and configured to perform a quality control measurement for measuring a measurement sample prepared from a quality control substance and a reagent corresponding to a measurement item; and a controller programmed to set a quality control for each measurement item, from a quality control group that includes at least two types of quality controls selected from a first quality control in which the quality control measurement is performed at a predetermined time, a second quality control in which the quality control measurement is performed every time the specimen measurement is performed a predetermined number of times of measurement, and a third quality control in which the quality control meType: GrantFiled: November 27, 2019Date of Patent: March 14, 2023Assignee: SYSMEX CORPORATIONInventor: Hiroshi Kurono
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Publication number: 20230075319Abstract: A smear system includes smear preparing apparatus that prepares a smear slide and a smear transporting apparatus that transports the smear slide to a smear-image capture apparatus. The smear preparing apparatus includes: a smear preparation part that smears a sample on a slide; and a smear arrangement part that places smear slides in a smear container. The smear transporting apparatus includes: a smear-container transport part that transports the smear container with the smear slides; an identification-information acquisition part that acquires identification information on whether image capturing by the smear-image capture apparatus is necessary, from each of the smear slides accommodated in the smear container positioned on a transport path of the smear-container transport part; and a smear transfer part that transfers the smear slide whose image is to be captured to the smear-image capture apparatus on the basis of the identification information acquired by the identification-information acquisition part.Type: ApplicationFiled: October 28, 2022Publication date: March 9, 2023Applicant: SYSMEX CORPORATIONInventors: Takayuki NAKAJIMA, Tetsuya ODA, Hiromi ONOMICHI, Kentaro TSURUMI, Seiya SHINABE
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Patent number: 11598952Abstract: An optical device comprises a shared phase modulation mask configured to impart a first phase modulation to light of a first wavelength, and imparts a second phase modulation to light of a second wavelength, an irradiation optical system configured to cause the light of the first wavelength and the light of the second wavelength to enter the same incident region in the phase modulation mask, and a light collecting optical system configured to collect the light of the first phase-modulated first wavelength and the light of the second phase-modulated second wavelength to form an image corresponding to a point spread function.Type: GrantFiled: January 14, 2019Date of Patent: March 7, 2023Assignee: SYSMEX CORPORATIONInventors: Masaya Okada, Shigeki Iwanaga
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Patent number: 11596485Abstract: A method for remotely supporting a surgery assistant robot may include: receiving at least one piece of operation information concerning an operation of the surgery assistant robot, by a server device that performs a remote support for the surgery assistant robot; and transmitting, in response to a predetermined event, at least one of a sound, an image, or a text from the server device to at least one of the surgery assistant robot or a terminal device.Type: GrantFiled: October 4, 2019Date of Patent: March 7, 2023Assignees: SYSMEX CORPORATION, MEDICAROID CORPORATIONInventors: Masanao Ohashi, Takehiko Sudoh, Shoko Ito, Jota Ida, Yasuyuki Fukuda
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Patent number: 11598724Abstract: A measuring apparatus includes a flow cell through which a sample containing particles flows, a light source for irradiating light on the sample flowing through the flow cell, a fluorescence detector for detecting the fluorescence generated from the sample irradiated with light from the light source, and a control unit for flowing a positive control sample containing a fluorescent dye through the flow cell, measuring the fluorescence generated from the positive control sample irradiated by the light from the light source via the fluorescence detector, comparing the obtained measurement value and a reference value, and adjusting the detection sensitivity of the fluorescence detector according to the comparison result.Type: GrantFiled: July 17, 2020Date of Patent: March 7, 2023Assignee: SYSMEX CORPORATIONInventors: Yasuaki Tsuruoka, Tomohiro Tsuji, Hiroo Tatsutani, Motoi Kinishi, Yuji Masuda
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Patent number: 11592365Abstract: A smear preparing apparatus that operates under selectable operation modes, may include: a smearing unit that prepares smeared slides by smearing samples onto slides; a staining unit that is capable of housing the smeared slides and that performs staining processing by accommodating a staining solution used to stain the samples on the housed smeared slides; a fluid circuit that supplies the staining solution to the staining unit; and a controller that controls the supplying of the staining solution to the staining unit depending on a selected one of the operation modes.Type: GrantFiled: June 25, 2020Date of Patent: February 28, 2023Assignee: SYSMEX CORPORATIONInventors: Junya Ikuta, Masaharu Shibata, Noriyuki Nakanishi, Mitsuo Yamasaki, Yuji Takano, Ken Nishikawa
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Patent number: 11592440Abstract: The present disclosure relates to a bioparticle measuring method including detecting a signal from a first measurement sample and a signal from a second measurement sample, wherein the first measurement sample is prepared by mixing a first sample containing a bioparticle sampled from a specimen with a detector capable of binding to the bioparticle and containing a labeled substance, in the presence of an inhibitor capable of binding to the bioparticle and containing none of the labeled substance. The second measurement sample is prepared by mixing a second sample sampled from the same specimen independently from the first sample with the detector, under a condition that the inhibitor is substantially absent. A measurement result is then calculated from the detected signals from the first and second measurement samples.Type: GrantFiled: July 25, 2019Date of Patent: February 28, 2023Assignee: SYSMEX CORPORATIONInventors: Takuya Iino, Keiko Yoshikawa, Kazuya Matsumoto
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Publication number: 20230055601Abstract: A urine analysis system according to an embodiment includes: a testing apparatus that measures particles included in a urine sample according to a flow cytometry method; an image capturing apparatus that captures images of particles in the urine sample to acquire particle images; and a management apparatus that receives a measurement result obtained by the testing apparatus and the particle images acquired by the image capturing apparatus. The management apparatus generates an order to capture an image of the urine sample based on the measurement result obtained by the testing apparatus. The image capturing apparatus executes the image capturing processing of the particles in the urine sample for which the image capturing order has been generated by the management apparatus, and transmits the acquired particle images to the management apparatus.Type: ApplicationFiled: October 19, 2022Publication date: February 23, 2023Applicant: SYSMEX CORPORATIONInventors: Masakazu FUKUDA, Masamichi TANAKA, Yousuke TANAKA
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Publication number: 20230028011Abstract: Disclosed is a disease differentiation support method for supporting disease differentiation, the disease differentiation support method including: obtaining a first parameter obtained by analyzing an image including a cell contained in a sample collected from a subject; obtaining a second parameter regarding a number of cells contained in the sample; and generating, by using a computer algorithm, differentiation support information for supporting disease differentiation, on the basis of the first parameter and the second parameter.Type: ApplicationFiled: September 28, 2022Publication date: January 26, 2023Applicants: JUNTENDO EDUCATIONAL FOUNDATION, SYSMEX CORPORATIONInventors: Akimichi OHSAKA, Yoko TABE, Konobu KIMURA
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Publication number: 20230019592Abstract: A transport system includes a sample rack configured to hold a sample and comprising a notch; a rack storage unit in which the sample rack is stored; a transport path arranged to transport the sample rack moved from the rack storage unit; and a regulating member configured to regulate movement of the sample rack from the rack storage unit toward the transport path, wherein the regulating member is provided at a position corresponding to the notch provided in the sample rack, and enters an interior of the sample rack from the notch and abuts an interior wall of the sample rack as the sample rack moves from the rack storage unit toward the transport path.Type: ApplicationFiled: September 16, 2022Publication date: January 19, 2023Applicant: SYSMEX CORPORATIONInventor: Kohei ODA
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Publication number: 20220412962Abstract: Disclosed is a detection method for detecting occurrence of nonspecific reaction in analysis for an antigen or an antibody contained in a biological sample with use of a measurement reagent containing an antibody or an antigen that causes antigen-antibody reaction with the antigen or the antibody in the biological sample, and the detection method includes: generating a data group about progress of antigen-antibody reaction between the antigen or the antibody contained in the biological sample and the antibody or the antigen contained in the measurement reagent; inputting the data group to a deep learning algorithm; and generating information about occurrence of nonspecific reaction, based on a result outputted by the deep learning algorithm.Type: ApplicationFiled: March 31, 2022Publication date: December 29, 2022Applicant: SYSMEX CORPORATIONInventors: Yuka TABUCHI, Konobu KIMURA, Keisuke NISHI, Osamu KUMANO, Takeshi SUZUKI
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Patent number: 11536735Abstract: A sample processing apparatus includes a pipette configured to dispense a sample or a reagent and an arm supporting the pipette. A camera is configured to capture an image of a tip end of the pipette and a container to which the sample or the reagent is dispensed. A controller is programmed to determine, based on the image, an adjustment value for the arm such that the pipette is inserted into the container without collision.Type: GrantFiled: December 17, 2019Date of Patent: December 27, 2022Assignee: SYSMEX CORPORATIONInventors: Junzo Yamamoto, Shigeo Kanamori, Fumio Inoue, Ikuya Takenaka, Osamu Hirota
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Patent number: 11535444Abstract: A glass slide set according to one or more embodiments may include: a stack of glass slides; and a packaging box that houses the stack. The packaging box may include: an exit opening through which the stack exits; and a push opening through which the stack is pushed, so that the stack exits through the exit opening.Type: GrantFiled: June 14, 2018Date of Patent: December 27, 2022Assignee: SYSMEX CORPORATIONInventors: Kazuhiro Oguchi, Atsushi Ishikawa, Shogo Kubota, Seiya Shinabe
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Patent number: 11531037Abstract: The present invention facilitates comprehension of the actual positions of constituent units of a sample measurement system regardless of a direction in which a user faces. The present invention provides a display device (6, 60) for displaying information about a sample measurement system (1) for measuring a sample, a display unit (509), a display control unit (101) that displays an image indicating an arrangement of a predetermined part of the sample measurement system on the display unit, and a receiving unit (102, 105) for receiving information on a display direction when displaying the arrangement of the predetermined part, wherein the display control unit (101) changes a display direction of the arrangement of the predetermined part according to the information.Type: GrantFiled: June 25, 2020Date of Patent: December 20, 2022Assignee: SYSMEX CORPORATIONInventors: Atsushi Kumagai, Yuji Wakamiya
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Patent number: 11525824Abstract: The present disclosure relates to a bioparticle measuring method including forming on a solid phase a complex of a sample containing a bioparticle sampled from a specimen, a capturer containing a tag which binds to the solid phase and capable of binding to the bioparticle, and a detector capable of binding to the bioparticle and containing a labeled substance. A part or the whole of the complex may be dissociated from the solid phase to prepare a measurement sample containing a part or the whole of the complex not fixed on the solid phase, and signals from the measurement sample may be detected by a particle analyzer.Type: GrantFiled: July 25, 2019Date of Patent: December 13, 2022Assignee: SYSMEX CORPORATIONInventors: Kazuya Matsumoto, Takuya Iino, Keiko Yoshikawa
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Patent number: 11521315Abstract: Disclosed is a fluorescence image analyzer for measuring and analyzing a sample that includes a plurality of cells in which target portions are labeled with fluorescent dyes, and the fluorescence image analyzer includes a light source configured to apply light to the sample; an imaging unit configured to take a fluorescence image of each of the cells by which fluorescence is generated by applying the light; a processing unit configured to process the fluorescence image having been taken; and a display unit.Type: GrantFiled: March 26, 2020Date of Patent: December 6, 2022Assignee: SYSMEX CORPORATIONInventor: Momoko Imakubo
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Patent number: 11511246Abstract: The present invention provides a cartridge, a detection method, and a detection device capable of stabilizing the liquid level of a sample accommodated in a chamber in a predetermined state. A cartridge 20, that is rotated around a rotating shaft 42 for detecting a target substance, is provided with a chamber 100 in which a sample containing a target substance is stored. The chamber 100 includes a first region 110 in which a sample is stored, a second region 120 disposed at a position closer to the rotating shaft 42 than the first region 110, and a protrusion 130 protruding from a position between the first region 110 and the second region 120 to the inner side of the chamber 100.Type: GrantFiled: September 27, 2018Date of Patent: November 29, 2022Assignee: SYSMEX CORPORATIONInventors: Yongjian Yang, Tomoyuki Nose, Sayuri Tomoda, Kazuyoshi Horii
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Patent number: 11506578Abstract: A smear system includes smear preparing apparatus that prepares a smear slide and a smear transporting apparatus that transports the smear slide to a smear-image capture apparatus. The smear preparing apparatus includes: a smear preparation part that smeares a sample on a slide; and a smear arrangement part that places smear slides in a smear container. The smear transporting apparatus includes: a smear-container transport part that transports the smear container with the smear slides; an identification-information acquisition part that acquires identification information on whether image capturing by the smear-image capture apparatus is necessary, from each of the smear slides accommodated in the smear container positioned on a transport path of the smear-container transport part; and a smear transfer part that transfers the smear slide whose image is to be captured to the smear-image capture apparatus on the basis of the identification information acquired by the identification-information acquisition part.Type: GrantFiled: July 28, 2017Date of Patent: November 22, 2022Assignee: SYSMEX CORPORATIONInventors: Takayuki Nakajima, Tetsuya Oda, Hiromi Onomichi, Kentaro Tsurumi, Seiya Shinabe
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Patent number: 11499908Abstract: A urine analysis system according to an embodiment includes: a testing apparatus that measures particles included in a urine sample according to a flow cytometry method; an image capturing apparatus that captures images of particles in the urine sample to acquire particle images; and a management apparatus that receives a measurement result obtained by the testing apparatus and the particle images acquired by the image capturing apparatus. The management apparatus generates an order to capture an image of the urine sample based on the measurement result obtained by the testing apparatus. The image capturing apparatus executes the image capturing processing of the particles in the urine sample for which the image capturing order has been generated by the management apparatus, and transmits the acquired particle images to the management apparatus.Type: GrantFiled: January 27, 2020Date of Patent: November 15, 2022Assignee: SYSMEX CORPORATIONInventors: Masakazu Fukuda, Masamichi Tanaka, Yousuke Tanaka