Patents Assigned to Sysmex Corporation
  • Patent number: 10379120
    Abstract: A blood analyzer including a specimen preparation unit, a flow cell, a light source unit, light receivers, and a processing unit. The processing unit is configured to identify and count lymphocytes in the first measurement specimen by using first scattered light information based on the first scattered light and second scattered light information based on the second scattered light, and configured to identify and count blood cells having thereon the predetermined surface antigen in the first measurement specimen by using first fluorescence information based on the first fluorescence.
    Type: Grant
    Filed: March 25, 2016
    Date of Patent: August 13, 2019
    Assignee: SYSMEX CORPORATION
    Inventors: Yuhgi Suzuki, Nozomu Higuchi
  • Patent number: 10379103
    Abstract: A urine sample testing apparatus may include a urine qualitative measuring section configured to acquire a measurement result for each of a plurality of urine qualitative measurement items and a urine sediment measuring section configured to acquire a measurement result for each of a plurality of urine sediment measurement items. The apparatus may also include an operation part that can specify a combination of one of the plurality of urine qualitative measurement items and one of the plurality of urine sediment measurement items. An information processing unit may also be included.
    Type: Grant
    Filed: April 10, 2017
    Date of Patent: August 13, 2019
    Assignee: SYSMEX Corporation
    Inventors: Toru Mizumoto, Keisuke Tsutsumida, Takayoshi Izumi
  • Patent number: 10369218
    Abstract: Disclosed is an immunostimulator containing virus-like particles, in which the virus-like particles contain an outer coat protein containing an amino acid sequence selected from the group consisting of SEQ ID No. 1, SEQ ID No. 26, SEQ ID No. 33, SEQ ID No. 35, SEQ ID No. 37, SEQ ID No. 39, SEQ ID No. 41, SEQ ID No. 43 and SEQ ID No. 45; the outer coat protein constitutes an outer coat of the virus-like particles; and the virus-like particles do not substantially contain a genome DNA of SV40.
    Type: Grant
    Filed: December 22, 2016
    Date of Patent: August 6, 2019
    Assignees: Saitama Medical University, SYSMEX CORPORATION
    Inventors: Hiroshi Handa, Masaaki Kawano, Masahiko Kato
  • Patent number: 10354224
    Abstract: A clinical laboratory system for managing clinical laboratory work is described that includes: an examination information input means for inputting examination information relating to clinical laboratory work; an examination information memory means for storing input examination information; an extraction means for extracting examination information meeting a predetermined extraction condition related to progress of an examination from among stored examination information; a screen preparation means for creating a progress management screen for displaying extracted examination information; and an output means for outputting the progress management screen. Methods and computer programs for managing clinical laboratory work, management devices, and terminal devices are also described.
    Type: Grant
    Filed: November 7, 2003
    Date of Patent: July 16, 2019
    Assignee: SYSMEX CORPORATION
    Inventor: Ryuichi Tohma
  • Patent number: 10352937
    Abstract: The present invention relates to a pretreatment method of a sample for detecting HBs antigen, which is a surface antigen of the hepatitis B virus, and a method for detecting HBs antigen utilizing the pretreatment method. The present invention also relates to a pretreatment reagent kit for detecting HBs antigen.
    Type: Grant
    Filed: July 27, 2015
    Date of Patent: July 16, 2019
    Assignee: SYSMEX CORPORATION
    Inventors: Takahiro Yamagaito, Takuya Koma, Mari Maruki, Kazuhiko Takeda
  • Publication number: 20190204304
    Abstract: A sample measurement device including: a dispensing mechanism that includes a nozzle capable of penetrating through a plug body that closes a sample container and of aspirating and discharging a sample housed in the sample container, and that dispenses the sample into a disposable container from the sample container through the nozzle; a cleaning mechanism that cleans the nozzle; and a first measurement section that performs measurement for an immunological test of the sample dispensed by the dispensing mechanism.
    Type: Application
    Filed: December 26, 2018
    Publication date: July 4, 2019
    Applicant: SYSMEX CORPORATION
    Inventors: Masaki Shiba, Hironori Katsumi, Tsuyoshi Fukuzaki
  • Publication number: 20190204349
    Abstract: A sample measurement method of performing first measurement for a blood coagulation test and second measurement for a test different from the blood coagulation test includes: dispensing a sample for use in the first measurement into a first container from a sample container; dispensing the sample for use in the second measurement into a second container different from the first container from the sample container from which the sample for use in the first measurement has been dispensed; performing the first measurement based on the sample dispensed into the first container; and performing the second measurement based on the sample dispensed into the second container.
    Type: Application
    Filed: December 26, 2018
    Publication date: July 4, 2019
    Applicant: SYSMEX CORPORATION
    Inventors: Shunsuke ARIYOSHI, Tsuyoshi FUKUZAKI, Masaki SHIBA
  • Publication number: 20190193272
    Abstract: A method of attaching a tip to a pipette, which is executed in a robot system, includes: making an end effector of a robot hold a pipette; bringing a vicinity portion of a distal end of the pipette into contact with or close to an edge of an opening formed in a base of a tip while tilting an axis direction of the pipette by a predetermined angle with respect to an axis direction of the tip; attaching the tip to the pipette by inserting the distal end of the pipette and the vicinity portion of the distal end of the pipette into the tip while raising the pipette such that the axis direction of the pipette is aligned with the axis direction of the tip; and separating the pipette and the tip attached to the pipette from the predetermined spot.
    Type: Application
    Filed: December 20, 2018
    Publication date: June 27, 2019
    Applicants: KAWASAKI JUKOGYO KABUSHIKI KAISHA, SYSMEX CORPORATION, MEDICAROID CORPORATION
    Inventors: Yukio IWASAKI, Satoshi OUCHI, Eiji MITSUI, Junichi MATSUOKA, Takehiro HASEGAWA, Yukihiko KITANO
  • Publication number: 20190195675
    Abstract: A liquid surface detecting apparatus including: a retaining section that retains liquid as sample or reagent; a light emitter that emits light toward the liquid retained in the retaining section; an image capturing device that captures an image of the liquid retained in the retaining section; and a detecting device that detects a level of a liquid surface of the liquid retained in the retaining section based on the image of the liquid captured by the image capturing device, wherein the image capturing device is provided at a position such that the light, emitted by the light emitter and reflected by the liquid surface of the liquid, directly enters the image capturing device.
    Type: Application
    Filed: December 20, 2018
    Publication date: June 27, 2019
    Applicants: KAWASAKI JUKOGYO KABUSHIKI KAISHA, SYSMEX CORPORATION
    Inventors: Yukio IWASAKI, Satoshi OUCHI, Eiji MITSUI, Junichi MATSUOKA, Takehiro HASEGAWA
  • Publication number: 20190195905
    Abstract: A dispensing method executed in a robot system including a pipette, a tip, a container, a liquid in the container, and a robot including a robot arm, an end effector, and a robot controller that controls the robot arm and the end effector to perform operations on the pipette and the tip, includes: making the end effector hold the pipette and the tip attached to the pipette; dipping at least a point of the tip attached to the pipette in the liquid and aspirating the liquid into the tip; bringing an outer surface of the tip attached to the pipette into contact with a part of the container, wherein the part of the container is at least one of an edge of an opening and an inside surface; and pulling the pipette and the tip attached to the pipette out of the container through the opening.
    Type: Application
    Filed: December 26, 2018
    Publication date: June 27, 2019
    Applicants: KAWASAKI JUKOGYO KABUSHIKI KAISHA, SYSMEX CORPORATION, MEDICAROID CORPORATION
    Inventors: Yukio IWASAKI, Satoshi OUCHI, Eiji MITSUI, Junichi MATSUOKA, Takehiro HASEGAWA, Yukihiko KITANO
  • Publication number: 20190195857
    Abstract: A dispensing apparatus that dispenses a sample into a well of a microplate, including a light emitter that emits light to the well, a light receiver that receives light emitted by the light emitter and returned from the well; and a control unit that determines whether foreign matter is present in the well based on information on the light received by the light receiver.
    Type: Application
    Filed: December 20, 2018
    Publication date: June 27, 2019
    Applicants: KAWASAKI JUKOGYO KABUSHIKI KAISHA, SYSMEX CORPORATION, MEDICAROID CORPORATION
    Inventors: Yukio IWASAKI, Satoshi OUCHI, Eiji MITSUI, Junichi MATSUOKA, Takehiro HASEGAWA, Yukihiko KITANO
  • Publication number: 20190195901
    Abstract: A dispensing robot of an assay robot system includes a first contact surface oriented in a downward direction or an obliquely downward direction in a vertical direction and dispenses when the dispensing robot operates a pipette that allows a tip to be attached to a lower end of the pipette and the attached tip to be detached by pressing a tip ejector, the dispensing robot comprising: a robot arm having a hand to hold a pipette holding piece attached thereto; and a controller controls the robot arm such that the robot arm holds the pipette with the tip attached thereto by causing the hand to hold the pipette holding piece and that the robot arm is elevated and the tip ejector is pressed by bringing an upper end portion of the tip ejector of the held pipette into contact with the first contact surface from the downward direction.
    Type: Application
    Filed: December 21, 2018
    Publication date: June 27, 2019
    Applicants: KAWASAKI JUKOGYO KABUSHIKI KAISHA, SYSMEX CORPORATION, MEDICAROID CORPORATION
    Inventors: Yukio IWASAKI, Satoshi OUCHI, Eiji MITSUI, Junichi MATSUOKA, Hiroya KIRIMURA, Yukihiko KITANO
  • Patent number: 10314301
    Abstract: The present invention relates to a method of preserving cells in a cell preservative solution. The cell preservative solution comprises a lower alcohol having 1 to 6 carbon atoms and a divalent metal ion in an aqueous solvent, wherein the concentration of the divalent metal ion is from about 6 mmol/L to about 82 mmol/L.
    Type: Grant
    Filed: July 14, 2017
    Date of Patent: June 11, 2019
    Assignee: SYSMEX CORPORATION
    Inventors: Koji Yokoyama, Noriko Oka, Masakatsu Morita, Yuka Yamamoto
  • Patent number: 10309877
    Abstract: Disclosed is a method for analyzing atypical cells in urine including: mixing urine, a diluent containing a surfactant, and a nucleic acid staining reagent to prepare a measurement specimen; irradiating the measurement specimen with light to detect scattered light and fluorescence light emitted from cells whose nucleic acids are stained; and detecting atypical cells contained in the measurement specimen distinguishably from white blood cells depending on a first characteristic parameter based on the scattered light and a second characteristic parameter based on the fluorescence light.
    Type: Grant
    Filed: August 20, 2015
    Date of Patent: June 4, 2019
    Assignee: Sysmex Corporation
    Inventors: Shota Tateyama, Masanori Kawano, Masatsugu Ozasa
  • Publication number: 20190162740
    Abstract: A sample measuring method of optically measuring a sample housed in a container in a sample measurement device, the method including: loading the container such that the container is shielded from light; starting to read information regarding a measurement to be performed on the sample in response to the loading the container; and measuring the sample based on the read information.
    Type: Application
    Filed: November 30, 2018
    Publication date: May 30, 2019
    Applicant: SYSMEX CORPORATION
    Inventors: Tomoyuki NOSE, Sayuri TOMODA, Yusuke MIIDA, Kazuyoshi HORII, Kenichiro SUZUKI
  • Publication number: 20190162670
    Abstract: A method according to one or more aspects may be a method of measuring a detection material contained in a sample by using a cartridge including: chambers each capable of housing at least one of the detection material and a reagent; and a path through which the detection material is transferred between the chambers. The method may include: moving at least one of the chambers and the path to a measurement position and an image capturing range by rotating the cartridge about a rotational shaft; measuring the detection material in the measurement position; and capturing an image of a monitoring target comprising at least one of the chambers and the path in the image capturing range.
    Type: Application
    Filed: November 28, 2018
    Publication date: May 30, 2019
    Applicant: SYSMEX CORPORATION
    Inventors: Tomoyuki NOSE, Yusuke MIIDA, Kanako NAGAOKA, Noriyuki NARISADA, Varun NAMBIGARI
  • Patent number: 10302666
    Abstract: A sample analyzing method of a sample analyzer for measuring samples, using a reagent container which comprises a writable and readable storage medium, the sample analyzing method including: storing information regarding a remaining amount of a reagent in the reagent container to a memory of the analyzer read from the storage medium; updating the information in the memory in response to an aspiration of the reagent; and writing updated information in the memory to the storage medium when an aspiration of the reagent in a plurality of measurements is completed. The writing of the updated information is postponed until the aspiration of the reagent in the plurality of measurements is completed.
    Type: Grant
    Filed: February 17, 2017
    Date of Patent: May 28, 2019
    Assignee: SYSMEX CORPORATION
    Inventors: Yuji Wakamiya, Kazutoshi Tokunaga
  • Publication number: 20190156481
    Abstract: The present invention provides an image analysis method for generating data indicating a region of a cell nucleus in an image of a tissue or a cell. The image analysis method is a method for analyzing an image of a tissue or a cell using a deep learning algorithm of a neural network structure, and generates data indicating a region of a cell nucleus in an analysis target image by the deep learning algorithm by generating analysis data from the analysis target image including an analysis target tissue or cell, and inputting the analysis data in the deep learning algorithm.
    Type: Application
    Filed: November 16, 2018
    Publication date: May 23, 2019
    Applicant: Sysmex Corporation
    Inventors: Yosuke Sekiguchi, Kazumi Hakamada, Yuki Aihara, Kohei Yamada, Kanako Masumoto, Krupali Jain
  • Publication number: 20190156476
    Abstract: An image analysis method for generating data indicating a tumorigenic state of an image of a tissue or a cell. The image analysis method is an image analysis method for analyzing an image of a tissue or a cell using a deep learning algorithm of a neural network structure, analysis data are generated from the analysis target image including a tissue or cell to be analyzed, the analysis data are input to the deep learning algorithm, and data indicating the tumorigenic state of tissues or cells in the analysis target image are generated by the depth learning algorithm.
    Type: Application
    Filed: November 16, 2018
    Publication date: May 23, 2019
    Applicants: National Cancer Center, SYSMEX CORPORATION
    Inventors: Hiroshi Yoshida, Yosuke Sekiguchi, Kazumi Hakamada, Yuki Aihara, Kohei Yamada, Kanako Masumoto, Krupali Jain
  • Patent number: 10295553
    Abstract: Disclosed is a blood analyzing method including: a step of preparing a measurement sample from blood, a fluorescent dye represented by the following formula 1, and a diluent, a concentration of the fluorescent dye in the measurement sample being greater than or equal to 0.15 ?M and smaller than or equal to 1.0 ?M; a step of acquiring fluorescence information obtained by irradiating the measurement sample with light; and a step of detecting a red blood cell infected with a malaria parasite in the blood based on the fluorescence information.
    Type: Grant
    Filed: August 22, 2016
    Date of Patent: May 21, 2019
    Assignee: SYSMEX CORPORATION
    Inventor: Yuhgi Suzuki