Abstract: Provided is a method for obtaining information on a risk of a decline in renal function in a patient with chronic kidney disease, comprising measuring a biomarker in a blood sample obtained from the patient with chronic kidney disease, wherein the biomarker comprises at least one selected from the group consisting of IL-22 and TNF-?, and a measurement result of the biomarker serves as an index for the risk of the decline in renal function.

Abstract: Disclosed is a maintenance method for an analyzer that is not communicably connected to a network outside of a facility, the maintenance method comprising: presenting, by a terminal that is communicably connected to the network outside of the facility, information about a process to be executed by the analyzer; reading, by the analyzer, the information having been presented by the terminal; and executing, by the analyzer, the process indicated by the information having been read.

Abstract: A sample measuring apparatus according to one or more embodiments may include a measuring unit that measures a sample in a container, a power supply that supplies power to the measuring unit, and an apparatus housing that accommodates the measuring unit and the power supply inside. In one or more embodiments, the power supply may be arranged in an area in the apparatus housing, the area that is the power supply is arranged is different from an area that the measuring unit is arranged in a plan view, and the power supply is arranged at a higher position than a position that the measuring unit is arranged.

Abstract: Disclosed is A reagent kit comprising: a reagent container comprising: a reagent storage bag configured to contain a reagent to be aspirated by a reagent aspiration tube provided in a sample analyzer, the reagent storage bag being made of flexible material and having an opening that allows the reagent aspiration tube to enter the reagent storage bag, and a sealing plug configured to seal the opening; and a protective member configured to protect the reagent container, wherein the protective member includes at least one of: a container hanging structure configured to hang the reagent storage bag in a state where a bottom portion of the reagent storage bag is not supported from its below and the opening is sealed by the sealing plug, and a container pressing structure configured to press the reagent storage bag from an outside in a state where the opening is sealed by the sealing plug.

Abstract: Provided is a method for measuring a polypeptide aggregate in a sample, wherein the method comprises obtaining information regarding a concentration of the polypeptide aggregate in the sample using a calibrator, and the calibrator comprises a complex comprising: an oligopeptide comprising an epitope of the polypeptide aggregate; a hydrophilic polymer chain not comprising the epitope; and a carrier particle.

Abstract: A sample analyzer includes: a measurement sample preparator configured to prepare a measurement sample from a sample aspirated by a sample aspiration tube and a reagent aspirated by a reagent aspiration tube from a reagent container; and a reagent container holder configured to hold the reagent container inserted therein. The reagent container includes: a reagent storage bag configured to contain the reagent, the reagent storage bag being made of flexible material and having an opening that allows the reagent aspiration tube to enter the reagent storage bag, and a sealing plug configured to seal the opening, the sealing plug being penetrable by the reagent aspiration tube. The sample analyzer further includes: a pressing part configured to press the reagent storage bag from an outside in a state where the reagent storage bag is in the reagent container holder and the opening is sealed by the sealing plug.

Abstract: Disclosed is an anti-HER2 antibody, in which three amino acid residues selected from the group consisting of positions 63, 65, 67, and 72 of a light chain defined by the Chothia method are changed to arginine residues, an amino acid sequence of the light chain excluding said three amino acid residues is not modified from an original amino acid sequence, and an amino acid sequence of a heavy chain is not modified.

Abstract: A system for a surgical assistance robot configured to perform a surgical procedure using a surgical instrument includes: a console including (i) a hand controller configured to be manipulated by a surgeon to remotely control an operation of the surgical instrument and comprising: joints rotatable by a manipulation of the hand controller, and (ii) a viewer configured to display images showing a surgical site and the operation; a storage configured to store (a) a video generated from the images and (b) a manipulation log representing a series of the manipulations. The manipulation log includes a rotation angle of each joint according to the manipulation; and a transmitter configured to transmit, to the console, the stored video and the manipulation log. The console is configured to rotate the joints according to the manipulation log associated with a playback of the video on the viewer for duplication of the manipulations.

Abstract: A sample measurement system using a cartridge for preparing a measurement sample from a sample and a plurality of types of reagents includes: a cartridge holder configured to detachably hold the cartridge containing the measurement sample in a measurement chamber having a transparent member; a photodetector provided so as to face one surface of the cartridge held by the cartridge holder and configured to detect, via the transparent member, light emitted from the measurement sample in the measurement chamber; a driver configured to move at least one of the cartridge held by the cartridge holder and the photodetector; and a controller configured to obtain a measurement result of a target component in the measurement sample based on the light detected by the photodetector.

Abstract: A smearing apparatus includes: a supply unit configured to store a plurality of slide glasses, each assigned with slide identification information, and to supply the slide glasses one by one; an aspirator configured to aspirate a specimen contained in a specimen container; a smearer configured to smear the aspirated specimen onto the slide glass supplied from the supply unit; a stainer configured to stain the specimen smeared on the slide glass with a staining solution; a first reader configured to read specimen identification information assigned to the specimen container; a second reader configured to read the slide identification information; and a controller configured to digitally associate (A) the slide identification information of the slide glass on which the specimen is smeared and (B) the specimen identification information of the smeared specimen, thereby enabling the analysis system to identify the specimen based on the slide identification information.

Abstract: A reagent container that stores a reagent that is aspirated by an aspiration tube installed in an analyzer according to one or more embodiments may include a bag-shaped reagent storage that stores the reagent; and a frame comprising an opening attached to the bag-shaped reagent storage. In one or more embodiments, an interior of the bag-shaped reagent storage may be sealed by inserting the aspiration tube into the opening from above in conjunction with a predetermined operation to the analyzer.

Abstract: A method for analyzing a cause of prolonging coagulation time of a blood specimen includes: adding a calcium solution to a first sample resulting from a first waiting time from mixing of a blood specimen from a subject and a measurement reagent for an activated partial thromboplastin time; obtaining a first coagulation time and/or a first parameter regarding a differential of a coagulation waveform, for the first sample; adding the calcium solution to a second sample resulting from a second waiting time, which is longer than the first waiting time, from mixing of the blood specimen from the subject and the measurement reagent; obtaining a second coagulation time and/or a second parameter regarding a differential of a coagulation waveform, for the second sample; and obtaining information regarding a cause of prolonging a coagulation time, on the basis of the first and second coagulation time and/or the first and second parameter.

Abstract: The invention allows a rack storage mode to be set in accordance with the situation in a facility. A testing system 1 includes a storage device 240 for storing a rack R holding containers A in which samples tested by the testing units 13 and 14 are accommodated, and the storage device 240 includes a table 130 capable of accommodating a plurality of racks R, a setting unit 230 for setting a first mode for starting storage of a plurality of racks R from a first end 130a of the table 130 and a second mode for starting storage of a plurality of racks R from a second end 130b of the table 130, and a moving device 102 for moving the rack R according to the mode set by the setting unit 230.

Abstract: [Problem] The problem is to provide a measure to enable a determination of whether a subject develops renal amyloidosis caused by proIAPP. [Solution] The above-mentioned problem is solved by measuring proIAPP in a biological sample from a subject, and using a result of the measuring as an indicator of proIAPP-type renal amyloidosis.

Abstract: The present disclosure relates to a multicolor flow cytometer system. The multicolor flow cytometer system includes a flow cytometer and a computer connected to the flow cytometer. The flow cytometer includes a flow cell to flow therein the measurement sample, light sources configured to irradiate with light, and light receiving elements configured to receive different colors of fluorescence from the fluorescent-labeled antibodies in the measurement sample. The computer includes a database storing antibody reagent information regarding a list of groups each of which includes combinable fluorescent-labeled antibodies. The computer executes operations in response to an input specifying target antigens to be measured, the operations including: determining, from the list, a plurality of the groups to detect the target antigens, wherein each of the determined groups comprises the fluorescent-labeled antibodies corresponding to the target antigens and presenting the determined groups.

Abstract: A urine analysis system according to an embodiment includes: a testing apparatus that measures particles included in a urine sample according to a flow cytometry method; an image capturing apparatus that captures images of particles in the urine sample to acquire particle images; and a management apparatus that receives a measurement result obtained by the testing apparatus and the particle images acquired by the image capturing apparatus. The management apparatus generates an order to capture an image of the urine sample based on the measurement result obtained by the testing apparatus. The image capturing apparatus executes the image capturing processing of the particles in the urine sample for which the image capturing order has been generated by the management apparatus, and transmits the acquired particle images to the management apparatus.

Abstract: A method and system for controlling a specimen analysis system including at least one measurement unit according to one or more embodiments is disclosed. The method may include automatically starting at least one measurement unit according to a schedule registered by a user; automatically supplying a quality control specimen to the measurement unit that is automatically started; and measuring the quality control specimen by the measurement unit.

Abstract: Disclosed is a specimen measurement system, comprising: a specimen including: a specimen suction part; a sample preparator; an optical detector; and a controller configured to control the specimen suction part, the sample preparator and the optical detector so that the specimen analyzer optically performs the measurement on the specimen; an imaging apparatus configured to capture images of blood cells of the specimen; and a computer capable of running an interface interacting with application software that executes operations including: receiving a request from the application software; retrieving the images corresponding to the request that are associated with metadata including morphological features of the blood cells; and providing the retrieved images to the application software to display, based on the metadata, a candidate having highest probability indicating classification for a specific blood cell in the retrieved images that visually demonstrate the morphological features and (2) probability of the

Abstract: Provided is a specimen measurement system operable to optically perform a measurement on a specimen, including: a specimen analyzer configured to optically perform the measurement on the specimen, including: (i) a specimen suction part configured to suction the specimen, including a nozzle to suction the specimen in a specimen container, a movement mechanism configured to move the nozzle into the specimen container and a pump configured to apply a negative pressure so that the nozzle suctions the specimen; (ii) a sample preparator configured to prepare a measurement sample by mixing the suctioned specimen and a reagent in a container; (iii) an optical detector configured to detect light from the prepared measurement sample; and (iv) a controller configured to control the specimen suction part, the sample preparator and the optical detector; an imaging apparatus configured to capture images of blood cells in a smear of the specimen; and a computer.

Abstract: Provided is a specimen measurement system operable to optically perform a measurement on a specimen, including: a specimen analyzer configured to optically perform the measurement on the specimen, including: (i) a specimen suction part configured to suction the specimen, the specimen suction part including a nozzle to suction the specimen in a specimen container, a movement mechanism configured to move the nozzle into the specimen container and a pump configured to apply a negative pressure so that the nozzle suctions the specimen; (ii) a sample preparator configured to prepare a measurement sample by mixing the suctioned specimen and a reagent in a container; (iii) an optical detector configured to detect light from the prepared measurement sample; and (iv) a controller configured to control, according to control software, the specimen suction part, the sample preparator and the optical detector so that the specimen analyzer optically performs the measurement on the specimen.