Patents Assigned to Sysmex Corporation
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Publication number: 20260266846Abstract: [Problem] The problem is to provide a measure to enable a determination of whether a subject develops renal amyloidosis caused by proIAPP. [Solution] The above-mentioned problem is solved by measuring proIAPP in a biological sample from a subject, and using a result of the measuring as an indicator of proIAPP-type renal amyloidosis.Type: ApplicationFiled: March 4, 2026Publication date: September 10, 2026Applicants: National University Corporation Kumamoto University, Sysmex CorporationInventors: Masayoshi TASAKI, Mitsuharu Ueda, Mitsuki Nakao, Niina Iwanaga, Masatoshi Yanagida, Masahiro Miura
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Publication number: 20260251648Abstract: The present disclosure relates to a multicolor flow cytometer system. The multicolor flow cytometer system includes a flow cytometer and a computer connected to the flow cytometer. The flow cytometer includes a flow cell to flow therein the measurement sample, light sources configured to irradiate with light, and light receiving elements configured to receive different colors of fluorescence from the fluorescent-labeled antibodies in the measurement sample. The computer includes a database storing antibody reagent information regarding a list of groups each of which includes combinable fluorescent-labeled antibodies. The computer executes operations in response to an input specifying target antigens to be measured, the operations including: determining, from the list, a plurality of the groups to detect the target antigens, wherein each of the determined groups comprises the fluorescent-labeled antibodies corresponding to the target antigens and presenting the determined groups.Type: ApplicationFiled: February 27, 2025Publication date: August 27, 2026Applicant: SYSMEX CORPORATIONInventors: Syunsuke YAO, Tomohiro TSUJI
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Patent number: 12718602Abstract: A urine analysis system according to an embodiment includes: a testing apparatus that measures particles included in a urine sample according to a flow cytometry method; an image capturing apparatus that captures images of particles in the urine sample to acquire particle images; and a management apparatus that receives a measurement result obtained by the testing apparatus and the particle images acquired by the image capturing apparatus. The management apparatus generates an order to capture an image of the urine sample based on the measurement result obtained by the testing apparatus. The image capturing apparatus executes the image capturing processing of the particles in the urine sample for which the image capturing order has been generated by the management apparatus, and transmits the acquired particle images to the management apparatus.Type: GrantFiled: October 19, 2022Date of Patent: August 25, 2026Assignee: SYSMEX CORPORATIONInventors: Masakazu Fukuda, Masamichi Tanaka, Yousuke Tanaka
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Publication number: 20260245684Abstract: Provided is a specimen measurement system operable to optically perform a measurement on a specimen, including: a specimen analyzer configured to optically perform the measurement on the specimen, including: (i) a specimen suction part configured to suction the specimen, including a nozzle to suction the specimen in a specimen container, a movement mechanism configured to move the nozzle into the specimen container and a pump configured to apply a negative pressure so that the nozzle suctions the specimen; (ii) a sample preparator configured to prepare a measurement sample by mixing the suctioned specimen and a reagent in a container; (iii) an optical detector configured to detect light from the prepared measurement sample; and (iv) a controller configured to control the specimen suction part, the sample preparator and the optical detector; an imaging apparatus configured to capture images of blood cells in a smear of the specimen; and a computer.Type: ApplicationFiled: February 13, 2026Publication date: August 20, 2026Applicant: SYSMEX CORPORATIONInventors: Tsukasa Nakamura, Takashi Karino
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Publication number: 20260243785Abstract: A method and system for controlling a specimen analysis system including at least one measurement unit according to one or more embodiments is disclosed. The method may include automatically starting at least one measurement unit according to a schedule registered by a user; automatically supplying a quality control specimen to the measurement unit that is automatically started; and measuring the quality control specimen by the measurement unit.Type: ApplicationFiled: April 3, 2026Publication date: August 20, 2026Applicant: SYSMEX CORPORATIONInventors: Yuji WAKAMIYA, Toru UEMURA, Yuichiro OHMAE, Hidetaka HAYAMA
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Publication number: 20260244683Abstract: Disclosed is a specimen measurement system, comprising: a specimen including: a specimen suction part; a sample preparator; an optical detector; and a controller configured to control the specimen suction part, the sample preparator and the optical detector so that the specimen analyzer optically performs the measurement on the specimen; an imaging apparatus configured to capture images of blood cells of the specimen; and a computer capable of running an interface interacting with application software that executes operations including: receiving a request from the application software; retrieving the images corresponding to the request that are associated with metadata including morphological features of the blood cells; and providing the retrieved images to the application software to display, based on the metadata, a candidate having highest probability indicating classification for a specific blood cell in the retrieved images that visually demonstrate the morphological features and (2) probability of theType: ApplicationFiled: February 13, 2026Publication date: August 20, 2026Applicant: SYSMEX CORPORATIONInventors: Tsukasa NAKAMURA, Takashi KARINO
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Publication number: 20260245683Abstract: Disclosed is a specimen measurement system operable to optically perform a measurement on a specimen, the specimen measurement system comprising: a specimen analyzer configured to optically perform the measurement on the specimen and analyze optical information which is derived from the detected light, and manages data relating to the specimen analyzer, an imaging apparatus configured to capture an image of blood cells in a smear of the specimen; and a computer capable of running an interface which interacts with application software programmed to utilize the data and the image, wherein the application software is independent of the specimen analyzer; the interface executes operations including: receiving a request from the application software; retrieving, according to a predetermined rule, the data and the image corresponding to the request; and providing the retrieved data and image to the application software so that the application software displays the data and the image.Type: ApplicationFiled: February 13, 2026Publication date: August 20, 2026Applicant: SYSMEX CORPORATIONInventors: Tsukasa NAKAMURA, Takashi KARINO
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Publication number: 20260243679Abstract: Provided is a specimen measurement system operable to optically perform a measurement on a specimen, including: a specimen analyzer configured to optically perform the measurement on the specimen, including: (i) a specimen suction part configured to suction the specimen, the specimen suction part including a nozzle to suction the specimen in a specimen container, a movement mechanism configured to move the nozzle into the specimen container and a pump configured to apply a negative pressure so that the nozzle suctions the specimen; (ii) a sample preparator configured to prepare a measurement sample by mixing the suctioned specimen and a reagent in a container; (iii) an optical detector configured to detect light from the prepared measurement sample; and (iv) a controller configured to control, according to control software, the specimen suction part, the sample preparator and the optical detector so that the specimen analyzer optically performs the measurement on the specimen.Type: ApplicationFiled: February 13, 2026Publication date: August 20, 2026Applicant: SYSMEX CORPORATIONInventors: Tsukasa NAKAMURA, Takashi KARINO
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Patent number: 12710437Abstract: Disclosed is a specimen testing system that includes: a specimen rearrangement unit configured to transfer a specimen container held in a first rack to a second rack; a specimen processing unit configured to process a specimen in the specimen container held in the second rack; a specimen storage unit configured to transfer the specimen container having been processed by the specimen processing unit from the second rack to a specimen container storage instrument for storage; a transportation unit configured to transport the second rack among the specimen rearrangement unit, the specimen processing unit, and the specimen storage unit; and a transportation control unit programmed to control the transportation unit. The transportation control unit is programmed to control bidirectional transportation of the second rack between the specimen rearrangement unit and the specimen storage unit.Type: GrantFiled: January 6, 2023Date of Patent: August 18, 2026Assignee: SYSMEX CORPORATIONInventors: Hidetaka Hayama, Yuichiro Ohmae, Toshiki Sato, Hiroyuki Tsuji
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Publication number: 20260217856Abstract: The present invention relates to a nucleic acid molecule having a nucleotide sequence encoding a chimeric antigen receptor (CAR). The present invention relates to a vector including the nucleic acid molecule. The present invention relates to a CAR. The present invention relates to an immune cell including the CAR. The present invention relates to a pharmaceutical composition including the immune cell including the CAR. The present invention relates to a method for producing an immune cell including the CAR.Type: ApplicationFiled: April 18, 2025Publication date: July 30, 2026Applicants: MIE UNIVERSITY, SYSMEX CORPORATIONInventors: Hiroshi SHIKU, Yasushi AKAHORI, Shingo MAETA, Atsushi FUKUNAGA
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Patent number: 12687555Abstract: Disclosed is a transport method to be performed in an analysis system configured to transport a specimen to an analyzer configured to analyze an analyte contained in the specimen, the transport method comprising: cooling and preserving, in a cooling-and-preserving part, a quality control specimen containing an analyte having a known concentration; and controlling transport of the quality control specimen between the cooling-and-preserving part and the analyzer on the basis of a status of the analyzer.Type: GrantFiled: May 24, 2023Date of Patent: July 21, 2026Assignee: Sysmex CorporationInventors: Atsushi Kumagai, Daigo Fukuma, Keisuke Kuwano, Toru Uemura, Koyo Hiroyama
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Patent number: 12674809Abstract: Disclosed is a specimen analysis method for analyzing a specimen regarding a plurality of measurement items, the specimen analysis method comprising: measuring a first measurement item and a second measurement item on the basis of a measurement order; executing a process related to a time difference between a measurement of the first measurement item and a measurement of the second measurement item; and obtaining a calculation value from a measurement value of the first measurement item and a measurement value of the second measurement item.Type: GrantFiled: December 16, 2022Date of Patent: July 7, 2026Assignee: SYSMEX CORPORATIONInventors: Naoya Kameyama, Tomoyuki Nishida, Yasuhiro Takeuchi, Takayuki Arai, Masahiro Mimura
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Publication number: 20260177542Abstract: Disclosed is a sample analysis system comprising: a plurality of measurement units, each configured to measure a sample to obtain a measurement result based on a measurement order including one or more measurement items; an identification information reader configured to read identification information of each of a plurality of first samples to be measured for diagnosis of a test subject by at least one of the plurality of measurement units; and a computer that is configured to: identify at least one of the plurality of first samples as a second sample used for a measurement for an inter-instrument difference evaluation, based on a timing to conduct the inter-instrument difference evaluation, wherein the timing is automatically determined by the computer; and control each of a plurality of target measurement units to measure the identified second sample based on a measurement order including one or more preset measurement items for the inter-instrument difference evaluation, and store a plurality of second meType: ApplicationFiled: December 9, 2025Publication date: June 25, 2026Applicant: SYSMEX CORPORATIONInventors: Yuto Nagao, Sakiko Uematsu, Gabi Bauer, Maros Heidinger
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Publication number: 20260177543Abstract: Disclosed is a sample analysis system comprising: a plurality of measurement units, each configured to measure a sample to obtain a measurement result based on a measurement order including one or more measurement items; an identification information reader configured to read identification information of each of a plurality of samples to be measured by at least one of the plurality of measurement units; and a computer that comprises a storage device configured to store the measurement results.Type: ApplicationFiled: December 9, 2025Publication date: June 25, 2026Applicant: SYSMEX CORPORATIONInventors: Yuto Nagao, Sakiko Uematsu, Gabi Bauer, Maros Heidinger
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Publication number: 20260177563Abstract: Disclosed is a sample analyzer comprising: a measurement unit configured to measure an analyte related to a dementia biomarker contained in a sample collected from a subject, the measurement unit comprising: a sample dispenser configured to aspirate the sample from a sample container and discharge the aspirated sample into a cuvette, a first reagent dispenser configured to aspirate a first reagent from a first reagent container and discharge the aspirated first reagent into the cuvette, wherein the first reagent immunologically reacts with the analyte, a second reagent dispenser configured to aspirate a second reagent from a second reagent container and discharge the aspirated second reagent into the cuvette, wherein the second reagent generates light corresponding to an amount of the reacted analyte, a detector configured to detect the generated light from a mixture of the sample, the first reagent, and the second reagent in the cuvette; a controller comprising a processor and programmed to obtain a measuremType: ApplicationFiled: December 23, 2025Publication date: June 25, 2026Applicant: SYSMEX CORPORATIONInventors: Kengo Ishiki, Kazuto Yamashita, Masahiro Miura
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Patent number: 12663359Abstract: In a configuration for analyzing data of cells measured by a cell measuring apparatus, accuracy of cell classification is improved without requiring the cell measuring apparatus to have high information processing capability. A cell analysis method, using a cell analyzer for analyzing cells in accordance with an artificial intelligence algorithm, includes: obtaining the data regarding the cells measured by the cell measuring apparatus; analyzing the data to generate information regarding a cell type of each of the cells; and transmitting the information to the cell measuring apparatus.Type: GrantFiled: March 17, 2023Date of Patent: June 23, 2026Assignee: SYSMEX CORPORATIONInventors: Shoichiro Asada, Konobu Kimura, Masamichi Tanaka, Kenichiro Suzuki, Kohei Nango
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Publication number: 20260153528Abstract: A specimen measurement system includes: a measurement unit configured to measure a specimen; and a control unit configured to analyze measurement data from the measurement unit. The measurement unit includes: a first reagent container accommodating a first reagent containing a substance that binds to an analyte in the specimen; a reagent holder configured to hold the first reagent container; a specimen processor configured to prepare a measurement sample by mixing the first reagent and the specimen; and a detector configured to interrogate the analyte for the measurement of the measurement sample. The measurement unit is arranged on a housing that stores a second reagent container, the second reagent container containing a second reagent used for at least one of: washing of a flow path of the measurement unit, dilution of the specimen, preparation of the measurement sample, and interrogation of the analyte of the measurement sample by the detector.Type: ApplicationFiled: November 27, 2025Publication date: June 4, 2026Applicant: SYSMEX CORPORATIONInventors: Takehiko Akakabe, Yasuhiro Ohyama, Takaaki Hadano
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Patent number: 12639674Abstract: A method for communicating information related to a diagnostic analyzer includes receiving user identification information from a portable computer. A user associated with the user identification information operates the diagnostic analyzer. First diagnostic analyzer information is retrieved from at least one database that relates analyzer information to the user of the diagnostic analyzer. The first diagnostic analyzer information is related to the diagnostic analyzer. The first diagnostic analyzer information is communicated to the portable computer. Second diagnostic analyzer information from the diagnostic analyzer is retrieved. The second diagnostic analyzer information is generated by the diagnostic analyzer. The first and the second diagnostic analyzer information is communicated to the portable computer. The portable computer is configured to display the first and the second diagnostic analyzer related information.Type: GrantFiled: September 20, 2024Date of Patent: May 26, 2026Assignee: Sysmex CorporationInventors: Judy Bosko, Mark Dahlberg, Chris Carrier, Mark Smith, Steve Postma, Masunao Nakahira, Tomomi Sugiyama, Mao Inoue
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Publication number: 20260137979Abstract: Disclosed is a system for supporting health management of an athletic player, comprising: a measuring device configured to measure myoglobin contained in blood of the player; and a server configured to record an exercise load of the player and a measured value of the myoglobin of the player, wherein the server is configured to provide the exercise load of the player and the measured value of the player in response to a request from a terminal.Type: ApplicationFiled: November 13, 2025Publication date: May 21, 2026Applicant: SYSMEX CORPORATIONInventors: Shunsuke Otsuka, Yasuyuki Kawashima, Takashi Endoh, Akiko Adachi
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Patent number: 12625154Abstract: A sample measuring device reduces the frequency with which a user introduces a measurement aid into the sample measuring device is provided. A sample measuring method measures a sample using a container containing a measurement aid which is a solid. The sample measuring method includes loading a predetermined number of measurement aids into a container from a storage chamber in which a plurality of measurement aids are movably stored in a cartridge attached to a sample measuring device, dispensing the sample into the container, and measuring the sample in the container into which the measurement aid has been loaded.Type: GrantFiled: December 23, 2022Date of Patent: May 12, 2026Assignee: SYSMEX CORPORATIONInventors: Kohei Oda, Hironori Katsumi, Yoshinori Nakamura