Abstract: Disclosed is a specimen testing system that includes: a specimen rearrangement unit configured to transfer a specimen container held in a first rack to a second rack; a specimen processing unit configured to process a specimen in the specimen container held in the second rack; a specimen storage unit configured to transfer the specimen container having been processed by the specimen processing unit from the second rack to a specimen container storage instrument for storage; a transportation unit configured to transport the second rack among the specimen rearrangement unit, the specimen processing unit, and the specimen storage unit; and a transportation control unit programmed to control the transportation unit. The transportation control unit is programmed to control bidirectional transportation of the second rack between the specimen rearrangement unit and the specimen storage unit.

Abstract: Disclosed is a method for improving affinity of an antibody for an antigen, comprising, in an unmodified antibody, improving affinity for an antigen as compared to the unmodified antibody, by changing 18th, 20th and 22nd amino acid residues of a light chain defined by Kabat method to charged amino acid residues.

Abstract: Disclosed is a method for improving affinity of an antibody for an antigen, comprising, in an unmodified antibody, improving affinity for an antigen as compared to the unmodified antibody, by changing 17th, 18th and 20th amino acid residues of a light chain defined by Kabat method to charged amino acid residues.

Abstract: Disclosed is a method for assisting prediction of onset of cerebral infarction, based on the number of red blood cells contained in a blood sample collected from a subject, comprising the steps of: calculating an exponent value for the prediction from a first measured value indicating red blood cell count measured by electrical resistance measurement method and a second measured value indicating red blood cell count measured by optical measurement method, comparing the exponent value with a reference range, and suggesting that the subject develops cerebral infarction when the exponent value is outside the reference range.

Abstract: In a configuration for analyzing data of cells measured by a cell measuring apparatus, accuracy of cell classification is improved without requiring the cell measuring apparatus to have high information processing capability. A cell analysis method, using a cell analyzer for analyzing cells in accordance with an artificial intelligence algorithm, includes: obtaining the data regarding the cells measured by the cell measuring apparatus; analyzing the data to generate information regarding a cell type of each of the cells; and transmitting the information to the cell measuring apparatus.

Abstract: In a dispensing system, a body is arranged outside a specimen processing cabinet, and in a state where a hand and a dispenser are inserted into the specimen processing cabinets, a specimen accommodated in a specimen container held by the hand is dispensed into a dispensing container by the dispenser.

Abstract: Disclosed is a specimen analysis method for analyzing a specimen regarding a plurality of measurement items, the specimen analysis method comprising: measuring a first measurement item and a second measurement item on the basis of a measurement order; executing a process related to a time difference between a measurement of the first measurement item and a measurement of the second measurement item; and obtaining a calculation value from a measurement value of the first measurement item and a measurement value of the second measurement item.

Abstract: A sample measuring device reduces the frequency with which a user introduces a measurement aid into the sample measuring device is provided. A sample measuring method measures a sample using a container containing a measurement aid which is a solid. The sample measuring method includes loading a predetermined number of measurement aids into a container from a storage chamber in which a plurality of measurement aids are movably stored in a cartridge attached to a sample measuring device, dispensing the sample into the container, and measuring the sample in the container into which the measurement aid has been loaded.

Abstract: Disclosed is a method for producing an antibody, comprising culturing in a presence of a polyanionic compound an animal cell into which a gene encoding an antibody has been introduced whereby the animal cell produces the antibody, wherein the polyanionic compound is at least one selected from the group consisting of an anionic polysaccharide and an anionic polyamino acid, and the antibody is an antibody in which at least 3 amino acid residues of framework region 3 (FR3) are substituted each independently with an arginine residue or a lysine residue.

Abstract: Disclosed is a method for sequencing a nucleotide sequence of a target nucleic acid. The method comprises: providing a pool of amplicons, wherein the pool of amplicons is prepared by attaching a unique identifier to the target nucleic acid, and amplifying by PCR the target nucleic acid to which the unique identifier is attached; and sequencing the amplicons comprising the unique identifier and the target nucleic acid. In the method, a nucleotide sequence of the unique identifier comprises both a random nucleotide (N) and a predetermined nucleotide.

Abstract: Disclosed is a method for detecting an antigen-specific activated T cell comprising: acquiring first information on a particle size and second information on a T cell activation marker for a first measurement sample prepared by mixing in vitro a first specimen separated from a biological sample containing a T cell and an antigen-presenting cell and an antigen reagent containing a predetermined antigen, by measuring the first measurement sample with a flow cytometer; acquiring the first information and the second information for a second measurement sample prepared from a second specimen separated from the biological sample and not containing the antigen reagent, by measuring the second measurement sample with the flow cytometer; detecting a target particle in the first measurement sample based on the first information and the second information on the first measurement sample, and detecting a background particle in the second measurement sample based on the first information and the second information on the

Abstract: A sample analyzer includes a suction unit configured to suction a sample in a sample container through a stopper installed in an opening of the sample container; a rack transport unit configured to transport a sample rack holding a sample container along a transport path, and position the sample container held by the sample rack at a suction position by the suction unit; a sample transport unit in which a sample container other than the sample container transported by the rack transport unit is installed and which is configured to transport the installed sample container to the suction position provided on the transport path; a measurement unit configured to measure a sample suctioned by the suction unit from the sample container positioned at the suction position; and an analysis unit configured to analyze the sample based on the measurement result of the measurement unit.

Abstract: Disclosed is a method for improving affinity of an antibody for an antigen, comprising, in an unmodified antibody, improving affinity for an antigen as compared to the unmodified antibody, by changing 5th, 9th and 22nd amino acid residues of a light chain defined by Kabat method to charged amino acid residues.

Abstract: A method for remotely supporting a surgery assistant robot may include: receiving at least one piece of operation information concerning an operation of the surgery assistant robot, by a server device that performs a remote support for the surgery assistant robot; and transmitting, in response to a predetermined event, at least one of a sound, an image, or a text from the server device to at least one of the surgery assistant robot or a terminal device.

Abstract: A thermal history detection label for detecting a thermal history over a temperature range to be monitored while suppressing an increase in label size is provided. The thermal history detection label is configured to detect a thermal history by the permeation of a molten permeating material into a permeation body, and the thermal history detection label includes a permeating material that integrally includes a first permeating material having a first melting point and a second permeating material having a second melting point higher than the first melting point, and a permeation body into which the permeating material permeates.

Abstract: A method for performing quality control on a diagnostic analyzer includes receiving control measurement values from each of a plurality of diagnostic analyzers. A quality control measurement value is received from a target diagnostic analyzer. The quality control measurement value is compared with statistical criteria associated with the plurality of quality control measurement values received from the plurality of diagnostic analyzers. A comparison result is communicated to a user interface associated with the target diagnostic analyzer.

Abstract: A urine sample testing apparatus may include a urine qualitative measuring section configured to acquire a measurement result for each of a plurality of urine qualitative measurement items and a urine sediment measuring section configured to acquire a measurement result for each of a plurality of urine sediment measurement items. The apparatus may also include an operation part that can specify a combination of one of the plurality of urine qualitative measurement items and one of the plurality of urine sediment measurement items. An information processing unit may also be included.

Abstract: A method of cleaning an aspiration tube in a specimen measuring apparatus includes: moving the aspiration tube while discharging a cleaning liquid onto an outer side surface of the aspiration tube; stopping the aspiration tube in a state where a tip of the aspiration tube or a droplet attached to the tip contacts a surface of a flow of the cleaning liquid; and moving the stopped aspiration tube in a direction away from the surface of the flow of the cleaning liquid.

Abstract: A report generating method generates a report for reporting a level of pathogenicity of a genetic mutation. The report generating method obtains information on a genetic mutation detected in a gene panel test, generates an evaluation result for a plurality of evaluation items based on a first criterion for evaluating each of the evaluation items and at least information on the genetic mutation, determines the level of pathogenicity based on a second criterion for determining the level of pathogenicity and the evaluation result, determines an undetermined item for which the evaluation result is undetermined among the plurality of evaluation items, determines whether the level of pathogenicity is tentative based on a determination result of the undetermined item, and generates a report for reporting the level of pathogenicity according to the determination result of whether the level of pathogenicity is tentative.

Abstract: A quality control sample measurement method, a sample analysis device and a supply device capable of normally acquiring a measurement result of a quality control sample are provided. The quality control sample measurement method for measuring a quality control sample stored in a cold state includes a step of stirring the quality control sample in a first operation mode (step S2) and a step of measuring the stirred quality control samples (step S3). The stirring in the first operation mode differs from the stirring in the second operation mode for stirring the subject sample collected from the subject.