Abstract: Disclosed is a transport method to be performed in an analysis system configured to transport a specimen to an analyzer configured to analyze an analyte contained in the specimen, the transport method comprising: cooling and preserving, in a cooling-and-preserving part, a quality control specimen containing an analyte having a known concentration; and controlling transport of the quality control specimen between the cooling-and-preserving part and the analyzer on the basis of a status of the analyzer.

Abstract: Disclosed is an image analysis method including inputting analysis data, including information regarding an analysis target cell to a deep learning algorithm having a neural network structure, and analyzing an image by calculating, by use of the deep learning algorithm, a probability that the analysis target cell belongs to each of morphology classifications of a plurality of cells belonging to a predetermined cell group.

Abstract: Disclosed is a method for producing an alkaline phosphatase fusion antibody, comprising: culturing a cell comprising an expression vector comprising a gene encoding alkaline phosphatase derived from bovine small intestine or Shewanella bacterium and a gene encoding an antibody in a medium comprising a zinc ion, and acquiring an alkaline phosphatase fusion antibody expressed by the cell.

Abstract: Disclosed is a method for obtaining information on von Willebrand factor (VWF), comprising the following steps: denaturing, with urea, VWF contained in a biological sample; fluorescently labeling the denatured VWF using a capturing agent that comprises a fluorescent substance and binds to the denatured VWF; and obtaining information on the size of the fluorescently-labeled VWF by fluorescence correlation spectroscopy or fluorescence cross-correlation spectroscopy.

Abstract: Disclosed is a medical robot system including medical robots placed at different locations and a data analysis apparatus. Each of the medical robots includes a controller that transmits data on a state of operation of the medical robot to the data analysis apparatus. The data analysis apparatus includes a data analysis unit that generates a reference for determining whether or not the medical robots are normal, based on the data transmitted from the medical robots. The data analysis unit monitors the data transmitted from each of the medical robots in operation based on the reference.

Abstract: Disclosed is a method for measuring an immunostimulatory response of an immune cell, including (i) bringing a measurement target immune cell into contact with an immunostimulator, (ii) forming a contact surface with a substance different from the measurement target immune cell on the measurement target immune cell, (iii) bringing the measurement target immune cell into contact with a capturing body that binds to a surface antigen on the contact surface and is capable of generating an optical signal, (iv) detecting the optical signal generated from the capturing body, and (v) determining whether or not the measurement target immune cell from which the contact surface has been eliminated before detecting the optical signal has an immunostimulatory response, based on the detected optical signal.

Abstract: Disclosed is a specimen rack transport device comprising: a transport mechanism configured to transport, on a placement surface, a specimen rack holding a specimen container; a flow path member configured to receive a specimen spilled from the specimen container onto the placement surface and cause the specimen to flow through the flow path member; and a collecting container configured to collect the specimen having flowed through the flow path member.

Abstract: A cell image analysis method may include: obtaining, for each of cell images, a value of a feature parameter to be used in determination of a type of a cell, by analyzing the cell images; and displaying the value of the feature parameter in association with the each of the cell images.

Abstract: Disclosed is a specimen analyzer configured to analyze an analyte in a specimen, the specimen analyzer including: a measurement unit including an optical detection part configured to obtain an optical signal from the specimen; and an analysis unit configured to analyze first data and second data that correspond to the optical signal, wherein the analysis unit executes, on the first data, a first analysis operation according to an artificial intelligence algorithm, and executes a second analysis operation of processing a representative value, of the second data, that corresponds to a feature of the analyte.

Abstract: Disclosed is a method for classifying white blood cells into subpopulations, comprising: preparing a measurement sample by mixing a specimen containing white blood cells, a hemolysis reagent containing a surfactant, a first fluorescent dye, and a second fluorescent dye; irradiating particles in the measurement sample with light, and detecting optical information including first fluorescence information based on fluorescence from the first fluorescent dye, second fluorescence information based on fluorescence from the second fluorescent dye, and scattered light information; sorting a cell population containing basophils from particles in the measurement sample based on optical information including the first fluorescence information; classifying white blood cells contained in the cell population into subpopulations based on the second fluorescence information and the scattered light information; and counting cells classified as a population of basophils in the subpopulation; wherein the second fluorescent dye

Abstract: Disclosed is a method for improving affinity of an antibody for an antigen, comprising, in an unmodified antibody, improving affinity for an antigen as compared to the unmodified antibody, by changing 3rd, 5th and 9th amino acid residues of a light chain defined by Kabat method to charged amino acid residues.

Abstract: A sample analyzer includes: a reagent container holder including a reagent container holder body configured to hold a reagent container, and a tilt changing part configured to change a tilt of the reagent container holder body; a reagent dispenser configured to aspirate a reagent contained in the reagent container held in the reagent container holder body; a detector configured to detect a signal for analysis from a measurement specimen containing a sample and the reagent dispensed by the reagent dispenser; and a controller that analyzes the sample on the basis of the signal detected by the detector.

Abstract: A specimen analysis system includes: a measurement data acquisition unit that acquires measurement data of particles obtained from a flow cytometer measuring the particles contained in a measurement specimen prepared by adding a reagent to a sample; an output mode information acquisition unit that acquires output mode information indicating an output form of the measurement data; and an output unit configured to output the measurement data in the output form in accordance with the output mode information.

Abstract: Disclosed is a specimen analysis cartridge that includes: a first base having a micro flow path formed in at least one surface; a second base disposed so as to oppose a surface at which the micro flow path of the first base is formed; and a photocurable resin layer for adhering the first base and the second base to each other, and the first base and the second base each contain at least one of cycloolefin polymer and cycloolefin copolymer.

Abstract: Disclosed is a fluorescence image analyzer for analyzing a fluorescence image of a cell contained in a sample. The fluorescence image analyzer includes a light source configured to apply light to the sample; an imaging unit configured to capture a fluorescence image of the cell by which fluorescence is generated by applying the light; and a processing unit configured to process the captured fluorescence image. The processing unit is programmed to obtain a bright point pattern of fluorescence in the captured fluorescence image; select at least one bright point pattern, from among a plurality of bright point patterns that include one or more positive patterns and are associated with at least one of a measurement item or a labeling reagent; and determine what positive pattern, among the selected at least one bright point pattern, corresponds to the obtained bright point pattern, based on the obtained bright point pattern and the selected at least one bright point pattern.

Abstract: Disclosed is a specimen analyzer for analyzing an analyte in a specimen, the specimen analyzer including: a measurement unit including a plurality of first sample preparation parts each configured to prepare a first measurement sample on the basis of the specimen and a first reagent, a second sample preparation part configured to prepare a second measurement sample on the basis of the specimen and a second reagent, and an optical detection part configured to obtain a first optical signal from the first measurement sample and obtain a second optical signal from the second measurement sample; and an analysis unit configured to analyze first data that corresponds to the first optical signal and second data that corresponds to the second optical signal, wherein the analysis unit executes analysis of a first measurement item with respect to the first measurement sample, through a first analysis operation of processing the first data according to an artificial intelligence algorithm, executes analysis of a second m

Abstract: Provided is a cell analysis method and a cell analyzer that, in a configuration in which data obtained from a plurality of cells contained in a specimen is analyzed, can process, at a requested throughput, data of cells having a significantly increased information amount. The cell analysis method, using a cell analyzer that comprises a host processor and a parallel-processing processor, includes: obtaining, on the basis of control by the host processor, data regarding each of a plurality of cells in a specimen; executing, by the parallel-processing processor, parallel processing regarding the data; and generating, on the basis of a result of the parallel processing, information regarding a cell type with respect to each of the plurality of cells.

Abstract: Disclosed are methods and reagents for the enzymatic measurement of short-chain fatty acids, having 3 to 6 carbon atoms, in a sample. Methods include the use of recombinant butyrate kinases from multiple species, combined various reagents that includes ATP, to detect butyric acid in different types of samples via measurement of ATP consumption. Disclosed also are the reagents themselves.

Abstract: Disclosed is a reagent container rack used in a specimen analyzer configured to analyze a specimen by use of a reagent. The reagent container rack includes a holder configured to hold a reagent container that contains the reagent; and a lid configured to cover a mouth portion of the reagent container to form an airtight space between the lid and the mouth portion.

Abstract: Disclosed is a test soil comprising a plurality of molecules of labeled polypeptides, wherein the labeled polypeptide is a polypeptide to which a dye is added by a covalent bond, and the value of X calculated by the following formula is 100,000 or more: X = Number of dyes comprised in one molecule of labeled polyeptide × Molar absorption coefficient of dye M -1 cm -1 .