Patents Assigned to Sysmex Corporation
  • Publication number: 20180356328
    Abstract: Disclosed is a particle analysis method for identifying infections, comprising: step A of irradiating light on a measurement sample prepared by mixing a test blood specimen containing particles, collected from a subject, a fluorescent dye that stains a nucleic acid, and a hemolytic agent, thereby acquiring scattered light and fluorescence from each particle contained in the measurement sample, step B of specifying particles that are substantially not contained in blood of control subjects not suffering from infection and are determined to be neutrophils contained in blood of patients with infection, based on the scattered light and the fluorescence, and acquiring particle number information on the specified particles, and step C of determining whether the test blood specimen is a specimen collected from patients with bacterial infection or a specimen collected from patients with viral infection, based on the particle number information.
    Type: Application
    Filed: June 8, 2018
    Publication date: December 13, 2018
    Applicant: SYSMEX CORPORATION
    Inventor: Konobu KIMURA
  • Patent number: 10151746
    Abstract: A sample analyzer prepares a measurement sample from a blood sample or a body fluid sample which differs from the blood sample; measures the prepared measurement sample; obtains characteristic information representing characteristics of the components in the measurement sample; sets either a blood measurement mode for measuring the blood sample, or a body fluid measurement mode for measuring the body fluid sample as an operating mode; and measures the measurement sample prepared from the blood sample by executing operations in the blood measurement mode when the blood measurement mode has been set, and measuring the measurement sample prepared from the body fluid sample by executing operations in the body fluid measurement mode that differs from the operations in the blood measurement mode when the body fluid measurement mode has been set, is disclosed. A computer program product is also disclosed.
    Type: Grant
    Filed: February 28, 2018
    Date of Patent: December 11, 2018
    Assignee: SYSMEX CORPORATION
    Inventors: Takaaki Nagai, Noriyuki Narisada, Daigo Fukuma, Masanori Imazu
  • Patent number: 10151696
    Abstract: Disclosed is a method for determining abnormality in a particle analyzer. The method includes: staining first control particles but not staining second control particles which emit fluorescence; irradiating with light the first control particles and the second control particles flowing in a flow cell, and detecting fluorescence from the first control particles and the second control particles; obtaining a first management value indicating a detection result of the fluorescence emitted from the first control particles and a second management value indicating a detection result of the fluorescence emitted from the second control particles; and determining abnormality in the staining step, based on a value calculated from the first management value and the second management value or a ratio between the first management value and the second management value.
    Type: Grant
    Filed: September 29, 2015
    Date of Patent: December 11, 2018
    Assignee: SYSMEX CORPORATION
    Inventors: Koji Yokoyama, Hiromi Morisaki
  • Publication number: 20180348212
    Abstract: Provided is a method for detecting a test substance, the method including the steps of: forming an immune complex on a first solid phase by bringing a test substance, a labeled antibody, a capture antibody and the first solid phase into contact with one another; transferring the immune complex onto a second solid phase by breaking the binding between the capture antibody and the first solid phase to liberate the immune complex, and bringing the second solid phase and the immune complex into contact with each other, where the second solid phase is bound to the capture antibody; and detecting the test substance by measuring a label contained in the complex on the second solid phase. The test substance detected by the method is a multimeric antigen, particularly amyloid ? or tau protein.
    Type: Application
    Filed: August 7, 2018
    Publication date: December 6, 2018
    Applicant: SYSMEX CORPORATION
    Inventor: Toshihiro WATANABE
  • Publication number: 20180349564
    Abstract: This specimen analyzer includes: an analysis unit which analyzes a specimen collected from a subject; a print unit which prints on a print sheet; a display unit which displays an operation screen; and a controller which performs control of causing the print unit to print an analysis result of the analysis unit, and prohibiting the display unit from displaying the analysis result.
    Type: Application
    Filed: May 31, 2017
    Publication date: December 6, 2018
    Applicant: Sysmex Corporation
    Inventors: Seiji TAKEMOTO, Takeshi KOMOTO, Hideki HIRAYAMA, Takashi YOSHIDA, James AUSDENMOORE
  • Publication number: 20180348242
    Abstract: The specimen analyzer includes: an input unit which receives an input of subject attribute information; an analysis unit which performs measurement of a specimen collected from a subject, and which performs analysis of the specimen based on a measurement result and the subject attribute information received by the input unit; and a controller which causes the analysis unit to be incapable of analyzing the specimen unless the input of the subject attribute information is performed with the input unit.
    Type: Application
    Filed: May 31, 2017
    Publication date: December 6, 2018
    Applicant: Sysmex Corporation
    Inventors: Seiji TAKEMOTO, Takeshi KOMOTO, Hideki HIRAYAMA, Takashi YOSHIDA, James AUSDENMOORE
  • Publication number: 20180348237
    Abstract: Disclosed is a method for measuring a clotting time, including the steps of: (A) mixing a blood sample, an activator, a phospholipid, and a nickel ion-forming compound to obtain a specimen; and (B) mixing the specimen obtained in step (A) with a calcium salt to prepare a measurement specimen and measuring the clotting time of the measurement specimen.
    Type: Application
    Filed: July 26, 2016
    Publication date: December 6, 2018
    Applicants: SYSMEX CORPORATION, SCHOOL JURIDICAL PERSON HIGASHI-NIPPON-GAKUEN
    Inventors: Osamu KUMANO, Haruki YAMAGUCHI, Takeshi SUZUKI, Masahiro IEKO
  • Publication number: 20180348243
    Abstract: This specimen analyzer includes: an analysis unit which analyzes a specimen collected from a subject; a manual input unit which receives an input of information by manual operation; an information read unit which receives an input of information by reading an information record section provided in a consumable; and a controller which does not permit an input of information on the consumable with the manual input unit, and permits an input of the information on the consumable with the information read unit.
    Type: Application
    Filed: May 31, 2017
    Publication date: December 6, 2018
    Applicant: Sysmex Corporation
    Inventors: Seiji TAKEMOTO, Takeshi KOMOTO, Hideki HIRAYAMA, Takashi YOSHIDA, James AUSDENMOORE
  • Publication number: 20180348241
    Abstract: A specimen analyzer includes: an analysis unit which analyzes a specimen collected from a subject and generates an analysis result including a component amount in the specimen; an output unit which outputs the analysis result; and a controller which causes the output unit to output or not to output the component amount based on a comparison between the component amount and a determination reference value.
    Type: Application
    Filed: May 31, 2017
    Publication date: December 6, 2018
    Applicant: Sysmex Corporation
    Inventors: Seiji TAKEMOTO, Takeshi KOMOTO, Hideki HIRAYAMA, Takashi YOSHIDA, James AUSDENMOORE
  • Patent number: 10145794
    Abstract: A cell information obtaining method comprises causing a plurality of fluorescent substances having different fluorescence wavelengths from each other to be bound to a test substance contained in a cell, applying light to the cell to cause fluorescences having different wavelengths and intensities to be generated from the plurality of fluorescent substances, and obtaining a first fluorescence information and a second fluorescence information on the basis of the generated fluorescences.
    Type: Grant
    Filed: October 27, 2016
    Date of Patent: December 4, 2018
    Assignee: SYSMEX CORPORATION
    Inventor: Keiko Yoshikawa
  • Patent number: 10145768
    Abstract: The time period necessary for a staining process is shortened, and the apparatus is downsized. This smear preparation apparatus includes: a staining vessel for storing a staining liquid therein so as to allow a plurality of glass slides each having a sample smeared thereon to be immersed therein; and a transfer unit for holding and transferring each glass slide. The staining vessel includes a plurality of first holders configured to hold the glass slides. The staining vessel is configured such that a plurality of glass slides held by a plurality of the first holders are immersed in the stored staining liquid, and the transfer unit is configured to put in/take out the glass slides one by one with respect to a plurality of the first holders of the staining vessel.
    Type: Grant
    Filed: May 19, 2017
    Date of Patent: December 4, 2018
    Assignee: SYSMEX CORPORATION
    Inventors: Yuichiro Ohmae, Seiya Shinabe, Kosuke Sekizuka
  • Patent number: 10145766
    Abstract: A smear preparing apparatus of an embodiment includes: a transportation part that holds and transports a microscope slide; a housing defining a room therein, the housing including: an insertion opening through which the microscope slide transported by the transportation part is to be inserted, and a feed opening through which air is to be fed; and a blower configured to feed the air through the feed opening to the microscope slide housed in the housing. The housing further includes a discharge opening through which the air fed from the blower through the feed opening is discharged.
    Type: Grant
    Filed: May 25, 2017
    Date of Patent: December 4, 2018
    Assignee: SYSMEX CORPORATION
    Inventors: Shogo Kubota, Seiya Shinabe, Kenji Kondo
  • Publication number: 20180340953
    Abstract: A specimen processing apparatus may include: an aspirating tube configured to aspirates a specimen in automatic aspiration and manual aspiration; an aspirating tube moving mechanism configured to move the aspirating tube between a first region in which the automatic aspiration is performed and a second region in which the manual aspiration is performed, the first region covered with a wall, the second region separated from the first region; and a processing unit that processes the specimen aspirated by the aspirating tube.
    Type: Application
    Filed: May 22, 2018
    Publication date: November 29, 2018
    Applicant: SYSMEX CORPORATION
    Inventor: Yuuichi HAMADA
  • Patent number: 10139319
    Abstract: A sample smearing apparatus of an embodiment includes: a first slide glass feeder that feeds a slide glass before processing; a slide glass transporter including a slide glass holder that holds the slide glass, that is capable of receiving the slide glass at a first slide glass feeding position from the first slide glass feeder, and transports the received slide glass while holding the slide glass with the slide glass holder; and a slide processor that performs processing on the slide glass held by the slide glass holder.
    Type: Grant
    Filed: April 27, 2017
    Date of Patent: November 27, 2018
    Assignee: SYSMEX CORPORATION
    Inventors: Shogo Kubota, Mitsuo Yamasaki, Seiya Shinabe
  • Publication number: 20180334702
    Abstract: Disclosed is a cyclin-dependent kinase substrate including a polypeptide that contains an amino acid sequence represented by formula (1): R1-P (wherein R1 represents a serine residue or a threonine residue, P represents a proline residue, “—” represents a single bond, and the left side represents the N-terminal side), and satisfies the following (a1) and/or (b1): (a1) the second amino acid residue counting from the proline residue toward the N-terminal side in the formula (1) is an aromatic amino acid residue, and/or (b1) at least two amino acid residues from the proline residue toward the C-terminal side in the formula (1) are acidic amino acid residues.
    Type: Application
    Filed: May 18, 2018
    Publication date: November 22, 2018
    Applicant: SYSMEX CORPORATION
    Inventors: Noriko Yokose, Masatoshi Suganuma, Kenta Noda, Naoki Nishiyama
  • Patent number: 10132819
    Abstract: Disclosed is a method for measuring a clotting time, including: a mixing step of mixing a blood sample, an activator, a phospholipid, and a manganese ion-forming compound to obtain a specimen; and a measurement step of mixing the specimen obtained in the mixing step with a calcium salt to prepare a measurement specimen and measuring the clotting time of the measurement specimen, wherein the blood sample is mixed with the manganese ion-forming compound separately from the activator and the phospholipid in the mixing step.
    Type: Grant
    Filed: July 26, 2016
    Date of Patent: November 20, 2018
    Assignees: SYSMEX CORPORATION, SCHOOL JURIDICAL PERSON HIGASHI-NIPPON-GAKUEN
    Inventors: Osamu Kumano, Haruki Yamaguchi, Takeshi Suzuki, Masahiro Ieko
  • Patent number: 10126292
    Abstract: A blood analyzer is provided that comprises: a measurement unit that measures a blood sample and outputs measurement data, a information processing unit that comprises a processor and a memory that stores a program to be executed by the processor to: analyze the measurement data outputted from the measurement unit, generate analysis data on each of blood cell types including red blood cells, white blood cells, and platelets, and generate support information for discriminating a cause of reduction in the number of blood cells of a predetermined type among the blood cell types from the analysis data comprising first analysis data on the predetermined blood cell type and second analysis data on a blood cell type other than the predetermined blood cell type, and an output unit that outputs the support information.
    Type: Grant
    Filed: March 23, 2015
    Date of Patent: November 13, 2018
    Assignee: SYSMEX CORPORATION
    Inventors: Masaki Abe, Tomohiro Tsuji
  • Patent number: 10119980
    Abstract: The present invention provides a method for detection of a basic peptide by mixing a sample suspected to contain the basic peptide and a reagent containing denatured albumin and detecting turbidness due to a complex of the basic peptide and denatured albumin.
    Type: Grant
    Filed: December 15, 2016
    Date of Patent: November 6, 2018
    Assignees: SYSMEX CORPORATION, Kagoshima University
    Inventors: Hiroyuki Kabata, Hideki Takahashi, Rena Tsuruoka, Ikuro Maruyama
  • Publication number: 20180313861
    Abstract: A transporting apparatus transports a container configured to be used by a sample analysis apparatus or a rack holding the container. The transporting apparatus may include a robotic arm that transports the container or the rack between a first sample analysis apparatus and a second sample analysis apparatus; and a base that supports the robotic arm.
    Type: Application
    Filed: April 27, 2018
    Publication date: November 1, 2018
    Applicants: SYSMEX CORPORATION, KAWASAKI JUKOGYO KABUSHIKI KAISHA
    Inventors: Kei TAKAI, Takaaki NAGAI, Yukio IWASAKI, Satoshi OUCHI
  • Publication number: 20180315190
    Abstract: An image analysis method according one or more embodiments may analyze a form of a cell using a deep learning algorithm with a structure of a neural network. The image analysis method may include: generating data for analysis from an image for analysis in which an analysis target cell is captured; inputting the data for analysis into the deep learning algorithm; and generating data indicating a form of the analysis target cell using the deep learning algorithm.
    Type: Application
    Filed: April 26, 2018
    Publication date: November 1, 2018
    Applicant: SYSMEX CORPORATION
    Inventors: Yoshinori SASAGAWA, Yoshiaki MIYAMOTO, Kazumi HAKAMADA, Kengo GOTOH, Yosuke SEKIGUCHI