Patents Assigned to Sysmex Corporation
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Patent number: 10113966Abstract: A blood analyzer comprises a light source unit configured to irradiate light on a measurement sample prepared from blood, a fluorescent light detecting unit configured to detect auto-fluorescence produced by red blood cells in the measurement sample which is irradiated by light, an information processing unit configured to obtain auto-fluorescence information related to red blood cells which produce auto-fluorescence detected by the fluorescent light detecting unit. The information processing unit is configured to make a determination regarding anemia based on the auto-fluorescence information.Type: GrantFiled: August 26, 2015Date of Patent: October 30, 2018Assignee: SYSMEX CORPORATIONInventors: Kazuhiro Yamada, Kazuhiro Sasaki, Seiichiro Tabata, Takeshi Yamamoto
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Patent number: 10107829Abstract: The present invention is to present an analyzing method for analyzing a target substance contained in a sample using a reagent containing magnetic particles. The method comprises steps of: (a) magnetically capturing magnetic particles in a container with a first magnetic force generating member arranged on a lower side of the container accommodating a liquid specimen containing the magnetic particles; (b) transferring the container to a target substance separating section after the step (a); and (c) in the target substance separating section, discharging a cleaning liquid into the container and aspirating a liquid in the container while magnetically capturing the magnetic particles in the container with a second magnetic force generating member.Type: GrantFiled: December 9, 2011Date of Patent: October 23, 2018Assignee: Sysmex CorporationInventors: Hiroto Toyoshima, Kazunori Mototsu
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Patent number: 10107754Abstract: A blood analyzer comprises a sample preparing part configured to prepare a measurement sample from a blood sample, an staining dye and diluent, a detecting part configured to detect the fluorescent light intensity and the scattered light intensity, an output part, and an analyzing part configured to identify the population including red blood cells infected by ring-form malaria parasite based on the fluorescent light intensity and the scattered light intensity, and output to the output part the information relating to infection of Plasmodium falciparum based on the scattered light distribution of particles associated with the identified population that includes red blood cells infected by the ring-form malaria parasite.Type: GrantFiled: August 29, 2016Date of Patent: October 23, 2018Assignee: SYSMEX CORPORATIONInventors: Yuhgi Suzuki, Munehisa Izuka, Konobu Kimura
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Publication number: 20180302742Abstract: A position management method according to one or more embodiments may use a mobile communication apparatus that is capable of obtaining position information. The method may include: receiving, by the mobile communication apparatus, a communication signal transmitted from an onboard communication device provided in a vehicle; and transmitting, from the mobile communication apparatus that receives the communication signal, the obtained position information to a management server.Type: ApplicationFiled: April 13, 2018Publication date: October 18, 2018Applicant: SYSMEX CORPORATIONInventor: Akihiko YASUDA
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Publication number: 20180299453Abstract: The present invention relates to a method for determining cancer, the method comprising the steps of: measuring free PD-L1 (Programmed cell death-ligand 1) and free PD-1 (Programmed cell death-1) as free protein markers in a liquid sample collected from a subject, and determining whether or not the liquid sample is a sample collected from a subject suffering from cancer, based on measurement results.Type: ApplicationFiled: June 22, 2018Publication date: October 18, 2018Applicants: SYSMEX CORPORATION, KYOTO UNIVERSITYInventors: Tasuku HONJO, Kenji CHAMOTO, Megumi GOTO, Hitoshi UGA
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Patent number: 10101345Abstract: Disclosed is a test strip pickup mechanism configured to pick up test strips for liquid sample analysis one by one from a test strip bottle, the test strip pickup mechanism including: a pickup head configured to suck and hold a test strip; and a motor for rotating the pickup head, wherein the pickup head is provided with a suction hole for sucking and holding the test strip, and the motor is a hollow motor, a hollow portion thereof being connected to the suction hole.Type: GrantFiled: March 23, 2016Date of Patent: October 16, 2018Assignee: SYSMEX CORPORATIONInventors: Satoshi Takai, Hanako Yura, Shingo Hatada, Yasuhiro Miyake
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Patent number: 10101348Abstract: The sample analyzer includes: a reagent arranging section for arranging a plurality of reagents; an analyzing section for analyzing a measurement sample prepared by mixing a sample and the reagent arranged on the reagent arranging section; a display device; an input device; and a display control section for displaying a reagent arrangement displaying region for displaying a plurality of reagent marks inscribed with a reagent name respectively on the display device, wherein the each reagent mark is displayed in a manner selectable by the input device, wherein arrangement of the each reagent mark on the reagent arrangement displaying region corresponds to arrangement of the each reagent on the reagent arranging section, wherein the display control section displays detailed information related to the reagent corresponding to the reagent mark selected by the input device on the display device.Type: GrantFiled: June 2, 2016Date of Patent: October 16, 2018Assignee: Sysmex CorporationInventors: Hiroyuki Fujino, Kyozo Fujita, Mitsuyo Ito
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Patent number: 10101346Abstract: In accordance with embodiments, a transport mechanism transports a first sample container to a sample aspiration position. A setting part may set a second sample container, that accommodates a sample to be measured, with priority over a measurement of a sample in a first sample container. A nozzle may be capable of moving a sample from a first sample container at a sample aspiration position, and aspirating the sample from the second sample container. A detector may detect components of the sample. A controller may control a transport mechanism such that the first sample container moves to a position distant from the sample aspiration position, when the first sample container has been transported and when sample aspiration of the second sample container is required. A controller may execute control to move the nozzle above the sample aspiration position in state in which the first sample container is distant from the sample aspiration position.Type: GrantFiled: May 27, 2016Date of Patent: October 16, 2018Assignee: SYSMEX CORPORATIONInventors: Hiroki Koike, Yousuke Matsui, Go Senda, Hiroo Tatsutani, Yuichiro Ohmae, Atsushi Kumagai, Tomoyuki Asahara
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Patent number: 10099866Abstract: A transport apparatus transports sample holder racks. The apparatus employs a first transport unit that moves the rack in a path between two ends of the transport apparatus, a rack sender unit that extends in a first direction that intersects the path, a second transport unit dimensioned parallel to the first transport unit and with the rack sender unit interposed therebetween, which locates the sample container held in the rack at a sample loading position of a measurement device, and a first movable member capable of moving in the first direction between the first and the second transport units. The apparatus has movable portions that alternately stop the rack movement, and push the rack such that optimal movement is achieved whereby the rack moves beyond the rack sender unit to the second transport unit as the first movable member moves in the first direction.Type: GrantFiled: August 28, 2015Date of Patent: October 16, 2018Assignee: SYSMEX CORPORATIONInventors: Yuichiro Ohmae, Hiroo Tatsutani, Nobuyoshi Yamakawa
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Publication number: 20180292385Abstract: Disclosed is a method for measuring an immunostimulatory response of an immune cell, including (i) bringing a measurement target immune cell into contact with an immunostimulator, (ii) forming a contact surface with a substance different from the measurement target immune cell on the measurement target immune cell, (iii) bringing the measurement target immune cell into contact with a capturing body that binds to a surface antigen on the contact surface and is capable of generating an optical signal, (iv) detecting the optical signal generated from the capturing body, and (v) determining whether or not the measurement target immune cell from which the contact surface has been eliminated before detecting the optical signal has an immunostimulatory response, based on the detected optical signal.Type: ApplicationFiled: April 10, 2018Publication date: October 11, 2018Applicant: SYSMEX CORPORATIONInventors: Masatoshi Yanagida, Keiko Miwa, Yuma Oka
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Patent number: 10094760Abstract: A particle measuring apparatus includes a flow cell configured to flow a specimen, a first light source configured to emit light having a first wavelength, and a second light source configured to emit light having a second wavelength different from the first wavelength. An irradiation optical system is configured to irradiate the flow cell with light emitted from the first light source and the second light source. The irradiation optical system includes a dichroic mirror configured to transmit the light emitted from the first light source and reflect the light emitted from the second light source, and a light collecting lens configured to collect the light emitted from the first and second light sources and passed through the dichroic mirror at the flow cell. The second light source and the dichroic mirror are turnable about rotation axis that are orthogonal to one another.Type: GrantFiled: November 2, 2016Date of Patent: October 9, 2018Assignee: SYSMEX CORPORATIONInventors: Kazuhiro Yamada, Takeshi Yamamoto
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Publication number: 20180271732Abstract: A patient placement table moving method may be used with a robotic operating table including a patient placement table, a base buried in or fixed to a floor and an articulated robotic arm including joints and having first and second ends. The first end may be supported on the base to be rotatable about an axis extending in a vertical direction. The second end may support the table. The method may include: horizontally arranging the table by the robotic arm at an imaging position for imaging with a medical imaging apparatus; and translating the table from the imaging position to a surgical operation position by the robotic arm. The surgical operation position may be away from the imaging position by 200 mm or more in a second direction orthogonal to a first direction in a horizontal plane, and the first direction is parallel with a longitudinal direction of the table.Type: ApplicationFiled: March 22, 2018Publication date: September 27, 2018Applicants: MEDICAROID CORPORATION, SYSMEX CORPORATIONInventors: Yutaro YANO, Yukihiko KITANO, Yoshiyuki TAMURA, Kenichi NAKAGAWA
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Publication number: 20180275029Abstract: Disclosed is a method for concentrating extracellular vesicles, comprising preparing a mixture comprising a first fraction and a second fraction by mixing a liquid sample comprising extracellular vesicles, a polysaccharide, and a polyether having an average molecular weight of 20,000 or less, wherein the first fraction comprises a higher concentration of extracellular vesicles than the second fraction, and the first fraction comprises a higher concentration of extracellular vesicles than the liquid sample.Type: ApplicationFiled: March 26, 2018Publication date: September 27, 2018Applicant: SYSMEX CORPORATIONInventors: Koya YAMAWAKI, Yuki AIHARA
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Publication number: 20180267069Abstract: A sample analyzer may include: a reagent table; a first reagent dispensing unit that dispenses a reagent from a reagent container in a first aspirating position into a reaction container; a second reagent dispensing unit that dispenses a reagent from a reagent container in a second aspirating position into a reaction container; a detection unit including detectors provided for holders that each hold a reaction container holding a measurement specimen containing a sample and the reagent dispensed by the first or the second reagent dispensing unit; and a controller that causes the reagent table to: transfer the reagent container, which holds the reagent relating to a measurement item for which the first reagent dispensing unit is used, to the first aspirating position; and transfer the reagent container, which holds the reagent relating to a measurement item for which the second reagent dispensing unit is used, to the second aspirating position.Type: ApplicationFiled: May 21, 2018Publication date: September 20, 2018Applicant: SYSMEX CORPORATIONInventors: Hironori KATSUMI, Shunsuke SAITO, Kohei ODA
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Publication number: 20180259545Abstract: A sample analyzer may include: a heating table including: holding holes in which reaction containers each housing a sample are held, respectively; and a heater that heats the reaction containers in the holding holes; a reagent dispensing unit that dispenses a reagent into the reaction containers heated on the heating table; a detection unit including: holders that hold the reaction containers each housing a measurement specimen, respectively; and detectors that detect analysis signals from the measurement specimens, respectively; a controller that analyzes each sample based on each analysis signal; a first transfer unit that transfers one of the reaction containers in the holding holes to one of the holders in a first region of the detection unit; and a second transfer unit that transfers one of the reaction containers in the holding holes to one of the holders in a second region of the detection unit.Type: ApplicationFiled: May 16, 2018Publication date: September 13, 2018Applicant: SYSMEX CORPORATIONInventors: Hironori KATSUMI, Shunsuke SAITO, Kohei ODA
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Patent number: 10073015Abstract: A sample smear apparatus of an embodiment includes: a slide feeder that feeds a slide glass before processing; a smear processor that smears a sample on the slide glass; and a slide transporter including a slide holder mechanism with an upper surface where to hold the slide glass and a transfer mechanism that moves the slide holder mechanism in a vertical direction and in a horizontal direction, the slide transporter arranged movably to the slide feeder and the smear processor.Type: GrantFiled: April 27, 2017Date of Patent: September 11, 2018Assignee: SYSMEX CORPORATIONInventors: Shogo Kubota, Mitsuo Yamasaki
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Patent number: 10073078Abstract: A blood coagulation analyzer and analyzing method perform following: (a) preparing a measurement specimen by dispensing a blood specimen and a reagent into a reaction container; (b) emitting light of a plurality of wavelengths to the measurement specimen in the reaction container, the wavelengths comprising a first wavelength for use in a measurement by a blood coagulation time method, and at least one of a second wavelength for use in a measurement by a synthetic substrate method and a third wavelength for use in a measurement by an immunoturbidimetric method; (c) detecting light of a plurality of wavelengths corresponding to the light emitted in (b), from the measurement specimen, by a light receiving element, and acquiring data corresponding to each wavelength; and (d) conducting an analysis based on the data corresponding to one of the wavelengths among the acquired data, and acquiring a result of the analysis.Type: GrantFiled: August 10, 2007Date of Patent: September 11, 2018Assignee: SYSMEX CORPORATIONInventors: Norimasa Yamamoto, Kazutoshi Tokunaga
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Patent number: 10073080Abstract: A sample analyzing apparatus comprising a measurement unit configured to measure samples obtained from subjects, an obtaining unit configured to obtain the presence or absence of a disease regarding each sample, a memory in which a measurement result obtained by the measurement unit and the presence or absence of the disease obtained by the obtaining unit are stored in association with the sample, and a communication unit configured to transmit disease information based on the presence or absence of the disease stored in the memory to a receiving apparatus installed in an external facility.Type: GrantFiled: July 15, 2014Date of Patent: September 11, 2018Assignee: SYSMEX CORPORATIONInventors: Akio Toyoda, Shinjirou Akamatsu
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Patent number: 10066261Abstract: The present invention relates to a method for amplifying a nucleic acid. More specifically, the present invention relates to a method for amplifying a nucleic acid in a light irradiation dependent manner under a substantially isothermal condition using a photo-responsive nucleic acid.Type: GrantFiled: October 20, 2015Date of Patent: September 4, 2018Assignees: SYSMEX CORPORATION, NATIONAL UNIVERSITY CORPORATION NAGOYA UNIVERSITYInventors: Seigo Suzuki, Hiroya Kirimura, Hiroyuki Asanuma
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Patent number: 10067116Abstract: Disclosed is a cell analyzer comprising: a measuring device that includes a collecting section configured to collect target cells in a specimen with a filter, and is configured to measure the target cells collected by the collecting section; and a data processing device configured to analyze the target cells based on measurement data obtained by the measuring device, wherein the cell analyzer is operable in a first mode of measuring a clinical specimen collected from a subject and a second mode of measuring a quality control specimen containing particles having size capturable by the filter; and the data processing device is programmed to acquire an amount of particles collected by the collecting section based on measurement data of the quality control specimen obtained in the second mode, and output an alarm when the amount of particles meets a predetermined condition.Type: GrantFiled: March 27, 2014Date of Patent: September 4, 2018Assignee: SYSMEX CORPORATIONInventors: Ryuichiro Ebi, Emi Kanemura, Kohei Murakami