Abstract: Disclosed is an analytical method for analyzing a test substance contained in a measurement sample, the method comprising: generating a data set based on a plurality of optical spectra acquired from a plurality of locations in the measurement sample; inputting the data set into a deep learning algorithm having a neural network structure; and outputting information on the test substance, on the basis of an analytical result from the deep learning algorithm.
Type:
Application
Filed:
March 4, 2022
Publication date:
September 8, 2022
Applicants:
SYSMEX CORPORATION, OSAKA UNIVERSITY, NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY
Abstract: Disclosed is a preparation method for preparing a measurement sample comprising an aggregate of metal nanoparticles having an analyte bound thereto, the preparation method comprising: contacting the analyte with a linker to bind the analyte to the linker; and contacting the linker that has been bound to the analyte with the metal nanoparticles to bind the linker to the metal nanoparticles.
Type:
Application
Filed:
March 4, 2022
Publication date:
September 8, 2022
Applicants:
SYSMEX CORPORATION, OSAKA UNIVERSITY, NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY
Abstract: An image analysis method for generating data indicating a tumorigenic state of an image of a tissue or a cell. The image analysis method is an image analysis method for analyzing an image of a tissue or a cell using a deep learning algorithm of a neural network structure, analysis data are generated from the analysis target image including a tissue or cell to be analyzed, the analysis data are input to the deep learning algorithm, and data indicating the tumorigenic state of tissues or cells in the analysis target image are generated by the depth learning algorithm.
Type:
Grant
Filed:
November 16, 2018
Date of Patent:
September 6, 2022
Assignees:
NATIONAL CANCER CENTER, SYSMEX CORPORATION
Abstract: Disclosed is a liquid-sealed cartridge that includes: a liquid storage portion configured to store liquid; a flow path in which the liquid stored in the liquid storage portion flows; and a liquid sealing portion configured to seal the liquid in the liquid storage portion, in which the liquid sealing portion has an outer circumferential portion and a center-side low strength portion disposed closer to a center than the outer circumferential portion, and the center-side low strength portion is broken when pressed, to allow the liquid in the liquid storage portion to flow in the flow path.
Abstract: A testing system according to one or more embodiments may include: a smear preparing apparatus that prepares a smear slide by smearing a sample on a glass slide; a smear transporting apparatus that transports the smear slide; a controller; and a display part. The controller may cause the display part to display a selection screen on which one or more of the smear preparing apparatus and the smear transporting apparatus can be selected. Based on a selection on the selection screen, the one or more of the smear preparing apparatus and the smear transporting apparatus selected on the selection screen may run respective start operations.
Type:
Application
Filed:
May 17, 2022
Publication date:
September 1, 2022
Applicant:
SYSMEX CORPORATION
Inventors:
Ken NISHIKAWA, Tetsuya ODA, Hidetaka HAYAMA
Abstract: Disclosed is a method for displaying a result of analysis performed on a specimen containing formed components. The method includes: obtaining, from each of the formed components, measurement values of at least three parameters; displaying a screen including a three-dimensional distribution chart in which the three parameters are used as axes and the formed components are represented by dots; and hiding specific dots on the three-dimensional distribution chart or changing a display format of the specific dots, according to an operation performed by a user.
Abstract: Disclosed is a control method for a specimen analysis system including an analyzer configured to analyze a specimen, the control method including: controlling, by a first computer, the analyzer; transmitting, by the first computer, an analysis result to a second computer communicably connected to the first computer via a network and configured to manage the analysis result; transmitting, by the first computer, setting information about a control program for the analyzer and setting information about communication with the second computer, to a third computer communicably connected to the first computer; storing, by the third computer, the setting information about the control program and the setting information about the communication which have been transmitted from the first computer; and controlling, by the third computer instead of the first computer, the analyzer on the basis of the stored setting information about the control program, and transmitting, by the third computer instead of the first computer
Abstract: Disclosed is an isolated monoclonal antibody comprising a heavy chain and a light chain, wherein the heavy chain comprises CDR1, CDR2 and CDR3 consisting of amino acid sequences set forth in SEQ ID NOs: 1, 2 and 3, respectively, and the light chain comprises CDR1, CDR2 and CDR3 consisting of amino acid sequences set forth in SEQ ID NOs: 4, 5 and 6, respectively.
Abstract: Disclosed is a method for acquiring information on exacerbation risk of COVID-19, comprising measuring IgM antibody against S antigen of SARS-CoV-2 contained in a specimen collected from a subject infected with SARS-CoV-2 or a subject suspected of suffering from COVID-19, wherein a value obtained by the measurement of IgM antibody serves as an index of exacerbation risk of COVID-19 of the subject.
Type:
Application
Filed:
February 18, 2022
Publication date:
August 25, 2022
Applicants:
NATIONAL CENTER FOR GLOBAL HEALTH AND MEDICINE, NATIONAL CANCER CENTER, SYSMEX CORPORATION
Abstract: Disclosed is a hemolytic reagent comprising a nonionic surfactant represented by formula (I) below: R1—R2—(CH2CH2O)n—H ??(I) where R1 represents an alkyl group, an alkenyl group, or an alkynyl group having 8 or more and 25 or less carbon atoms, R2 represents an oxygen atom, (COO) or a group represented by formula (II) below: where n is 23 or larger and 25 or smaller, or 30, with n of 23 or larger and 25 or smaller, a concentration of the nonionic surfactant is 1700 ppm or higher and 2300 ppm or lower, and with n of 30, the concentration of the nonionic surfactant is 1900 ppm or higher and 2300 ppm or lower.
Abstract: Disclosed is a specimen smearing apparatus including: a slide supplying section configured to supply a glass slide yet to be processed; a first processing section configured to perform a first process on the glass slide, the first processing section being disposed in a first direction with respect to the slide supplying section, the first direction being a far direction of an apparatus body of the specimen smearing apparatus; a second processing section configured to perform on the glass slide a second process which is different from the first process, the second processing section being disposed in a second direction with respect to the first processing section, the second direction being a left-right direction of the apparatus body and orthogonal to the first direction; and a first drying processing section disposed in a third direction with respect to the second processing section, the third direction being a near direction of the apparatus body and opposite to the first direction, the first drying process
Abstract: The sample measuring apparatus includes a suction unit that includes a nozzle and a drive unit that raises and lowers the nozzle, and suctions a first liquid and a second liquid that is different from the first liquid; a liquid surface detecting unit that detects liquid surfaces of the first liquid and the second liquid; a control unit that controls the suction unit, and a measuring unit that measures a measurement sample prepared from the suctioned first liquid; wherein the control unit controls the suction unit to suction the first liquid and the second liquid based on the respective liquid surface detection result of the first liquid and the second liquid detected while lowering the nozzle, and a second speed at which the nozzle descends when detecting the liquid surface of the second liquid is faster than a first speed at which the nozzle descends when detecting the liquid surface of the first liquid.
Type:
Grant
Filed:
February 26, 2019
Date of Patent:
August 23, 2022
Assignee:
SYSMEX CORPORATION
Inventors:
Takashi Yamato, Jun Inagaki, Shunsuke Saito, Yoshinori Nakamura
Abstract: The present invention is directed to suppress adhesion of a reagent to the periphery of an opening of a reagent container. The reagent container is a reagent container used for a sample measuring apparatus having a suction tube for suctioning a reagent, and includes a reagent, an upper surface part having an opening, a side surface part, and a bottom surface part that defines an internal space in which the reagent is stored, and a suction tube introducing part extending from the upper surface part to a position above the liquid level of the reagent to introduce the suction tube received from above the opening into the internal space.
Abstract: Disclosed is a management method for managing temperature information of a transported cargo by a blockchain system. A management method according to one or more embodiments may include: obtaining, by a user terminal used in the blockchain system, data about a temperature from a thermometer transported together with the cargo, and transmitting, by the user terminal, the data to the blockchain system in order to register information about presence or absence of temperature deviation.
Abstract: A sample scraping method and a sample scraping device capable of efficiently scraping and collecting a biological tissue section without waste while suppressing contamination is provided. In a sample scraping method for scraping and collecting a biological tissue section held on a slide, the FFPE section held on the slide is heated, and the heated FFPE section is scraped by a blade such that the FFPE section that has been scraped off and remains on the blade is collected in a container.
Abstract: A sample analyzer prepares a measurement sample from a blood sample or a body fluid sample which differs from the blood sample; measures the prepared measurement sample; obtains characteristic information representing characteristics of the components in the measurement sample; sets either a blood measurement mode for measuring the blood sample, or a body fluid measurement mode for measuring the body fluid sample as an operating mode; and measures the measurement sample prepared from the blood sample by executing operations in the blood measurement mode when the blood measurement mode has been set, and measuring the measurement sample prepared from the body fluid sample by executing operations in the body fluid measurement mode that differs from the operations in the blood measurement mode when the body fluid measurement mode has been set, is disclosed. A computer program product is also disclosed.
Abstract: A method for communicating information related to a diagnostic analyzer includes receiving user identification information from a portable computer. A user associated with the user identification information operates the diagnostic analyzer. First diagnostic analyzer information is retrieved from at least one database that relates analyzer information to the user of the diagnostic analyzer. The first diagnostic analyzer information is related to the diagnostic analyzer. The first diagnostic analyzer information is communicated to the portable computer. Second diagnostic analyzer information from the diagnostic analyzer is retrieved. The second diagnostic analyzer information is generated by the diagnostic analyzer. The first and the second diagnostic analyzer information is communicated to the portable computer. The portable computer is configured to display the first and the second diagnostic analyzer related information.
Type:
Application
Filed:
April 25, 2022
Publication date:
August 11, 2022
Applicant:
SYSMEX CORPORATION
Inventors:
Judy Bosko, Mark Dahlberg, Chris Carrier, Mark Smith, Steve Postma, Masunao Nakahira, Tomomi Sugiyama, Mao Inoue
Abstract: A reagent kit in which a brief measurement result is readily associated with subject information by suppressing erroneous input without using an integrated management system. This reagent kit 100 includes a container 10 used for measuring a sample by the sample measuring apparatus 300, a first identification label 30 including first identification information 31 associated with the measurement result 51 of the sample, and a second identification label 40 including second identification information 41 associated with the first identification information 31.
Type:
Grant
Filed:
November 29, 2018
Date of Patent:
August 9, 2022
Assignee:
SYSMEX CORPORATION
Inventors:
Koji Ikeda, Hiroyuki Fujino, Mieko Asada
Abstract: A smear staining apparatus may include: a chamber part in which glass slides can be placed and that is configured to contain a staining solution for staining a smear on each of the glass slides; a cover part that covers the chamber part from above and comprises an insertion hole through which the glass slides are transported to the chamber part; and a transport part that transports the glass slides to the chamber part through the insertion hole.
Abstract: A sample measuring system to reduce waste generated in a plurality of measurement units to be discarded to a common disposal unit while suppressing interference between measurement units due to waste disposal is provided. The sample measuring system includes a first measurement unit and a second measurement unit for measuring a sample, and a common disposal unit for storing waste generated from the first measurement unit and the second measurement unit. The first measurement unit includes a first disposal port connected to the disposal unit for discharging the waste generated in the first measurement unit. The second measurement unit includes a second disposal port connected to the disposal unit for discharging the waste generated in the second measurement unit.