Abstract: The present disclosure provides systems and methods for wirelessly charging an implantable medical device. An external charging device includes a coil, signal generating circuitry to drive current through the coil at a charging frequency to induce current in a second coil in the implantable medical device, monitoring circuitry to generate an output signal to monitor charging operations, and a comb filter. The comb filter is configured to apply filtering to the output signal to remove noise from the output signal, wherein the filtering is applied based on the charging frequency. The external charging device is configured to process the filtered output signal to detect a circuit state of charging circuitry of the implantable medical device during charging operations, and the external charging device is configured to vary the charging frequency based, in part, on detection of the circuit state of the charging circuitry of the implantable medical device.

Abstract: A memory view generator evaluates a Liberty file characterizing an NVM module to generate a memory view file for the NVM module. The memory view file includes a port alias identifying ports of the NVM module. The port alias for a set of ports of the NVM module characterizes a type of port in the set of ports. The memory view file includes a port action identifying ports of the NVM module that have a static value and a port access identifying ports of the NVM module that have a dynamic value. The memory view file has an address limit characterizing a number of words in the NVM module and an address partition characterizing address bits and data bits. The memory view file includes a read delay that defines a number of clock cycles needed to hold an address bus stable after a strobe port transitions to an inactive state.

Abstract: A satellite orbiting in one of a plurality of orbital planes of a satellite constellation system at an altitude range corresponding to low earth orbit includes at least one processor configured to generate satellite state data, and to generate a navigation signal based on the satellite state data. The satellite includes at least one transmitter configured to transmit the navigation signal for receipt by at least one client device on earth. Each of the plurality of orbital planes includes a corresponding one of a plurality of satellite subsets of a plurality of satellites of the satellite constellation system. Each of the plurality of orbital planes is within the altitude range, and the plurality of orbital planes includes a set of inclined orbital planes at a non-polar inclination.

Abstract: The invention provides modular cell-free de-novo synthesis of glycans with immobilized bionanocatalysts. The invention provides materials, and in particular, magnetic materials, for producing glycans of defined length and sequences using one or more enzymes that are immobilized within bionanocatalysts (BNCs) which in turn are embedded within scaffolds to control the synthesis in batch or continuous processes manufacturing. In some embodiments, the scaffolds are high magnetism and high porosity composite blends of thermoplastics or thermosets comprising magnetic particles that form powders. In some embodiments, Selective Laser Sintering (SLS) is used to design and produce objects via 3D printing by sintering composite magnetic powders. The modular flow cells may be mixed and matched for a highly customizable and highly efficient cell-free manufacturing process. In some embodiments the elementary and system modules provided by the invention are employed.

Abstract: Polymers derived from a metallocene comprising a group IV element and at least one cyclopentadienyl group are described. Methods for preparing refractory ceramics comprising group IV carbides and/or borides using such polymer are also disclosed. In some embodiments, the method for fabricating the refractory ceramic comprises infiltrating a fiber preform with such polymer and pyrolyzing the polymeric fiber preform.

Abstract: Systems and methods described herein relate, among other things, to unmixing more than three stains, while preserving the biological constraints of the biomarkers. Unlimited numbers of markers may be unmixed from a limited-channel image, such as an RGB image, without adding any mathematical complicity to the model. Known co-localization information of different biomarkers within the same tissue section enables defining fixed upper bounds for the number of stains at one pixel. A group sparsity model may be leveraged to explicitly model the fractions of stain contributions from the co-localized biomarkers into one group to yield a least squares solution within the group. A sparse solution may be obtained among the groups to ensure that only a small number of groups with a total number of stains being less than the upper bound are activated.

Abstract: A streamlined approach enables customers to retain management control over their data in a database-as-a-service (“DBaaS”) setting, by providing managed backup copies outside cloud service providers' sphere of control. An illustrative data storage management system provides control over performing backup operations to generate managed backup copies, storing managed backup copies, recovering managed backup copies in whole or in part, migrating managed backup copies, and migrating DBaaS instances. Management control also extends to choices of where to store the managed backup copies, whether on the same cloud computing platform as the source DBaaS, on a different cloud computing platform, and/or in a non-cloud data center.

Abstract: This invention is directed to an expandable stent for implantation in a body lumen, such as an artery, and a method for making it from a single length of tubing. The stent consists of a plurality of radially expandable cylindrical elements generally aligned on a common axis and interconnected by one or more links. A Y-shaped member is comprised of a U-shaped member and a link having a curved portion and a straight portion to improve the flexibility and thereby improve the fatigue performance of the Y-link junction.

Abstract: A system can include an emitter structure connected to a reservoir containing a working material, wherein the working material is in electrical communication with a first electrode, an electrode opposing the emitter structure across a gap; and optionally a frame holding the emitter structure and the electrode.

Abstract: A virtualization server may include a memory and a processor cooperating therewith to operate a virtual session controller configured to assign virtual sessions to a plurality of different client devices. Each virtual session may be running on a virtual machine from among a plurality of different virtual machines and having a respective user profile associated therewith stored at a cloud computing service, and the cloud computing service may be distributed over a plurality of different geographic locations and configured to store the user profiles and backups thereof at different geographic locations. The controller may further receive the user profiles from the cloud computing service and, as client devices are assigned virtual sessions on different virtual machines, roam the user profiles to the different virtual machines, and synchronize local profile changes during the virtual sessions on different virtual machines back to the user profiles stored at the cloud computing service.

Abstract: This application is generally related to identifying or otherwise programming one or more cycling parameters for operation of an implantable pulse generator to provide a neurostimulation therapy to a patient using a non-paresthesia stimulation pattern. In some embodiments, the cycling parameter is selected by measuring physiological signals during trial stimulation. In other embodiments, multiple cycling parameters are identified for use by the patient using a patient controller device.

Abstract: The present disclosure relates to reversible sealing of a microfluidic chip used for thermal incubation of an aqueous sample suspected to contain a target nucleic acid. The microfluidic chip contains a flow channel and a plurality of reaction compartments, into which the sample and a displacement fluid are introduced through an inlet port sealable by means of a sealing agent having a melting point above room temperature.

Abstract: Systems and methods for providing a solar cell array with a reduced magnetic field are provided. The systems include a plurality of solar cells arrayed on a first surface side of a substrate. The solar cells are electrically connected to one another in series by a first conductor structure at least partially disposed on the first surface side of the substrate, forming a solar cell or supply circuit. A second conductor structure in series with the solar cell circuit is at least partially disposed on the second surface side of the substrate, forming a return harness. The supply circuit and the return harness define current paths that are opposite one another, and that are separated from one another by the substrate. The first and second conductor structures can be formed from conductive traces on the first and second sides respectively of the substrate.

Abstract: Medical devices for delivering a plug to a void within a patient. The medical device can include a fluid delivery device and a plug holder (e.g., a plug delivery device) coupled to a distal end of the fluid delivery device. The medical device may be configured such that the delivery of fluid from the fluid delivery device wets the plug, ejects the plug from the plug holder, and pushes the plug through a lumen of an elongate tube to a void within a patient.

Abstract: The system 100 can include: a fleet management system, a motion planner, a vehicle controller, and a track data system. The system can optionally include a user interface. However, the system 100 can additionally or alternatively include any other suitable set of components. The system functions to facilitate waypoint-based command, navigation, and/or control of rail vehicles within a rail network. Additionally or alternatively, the system can function to facilitate execution of the method S100 and/or sub-elements thereof.

Abstract: Light weight lens barrel systems and methods are provided. In one example, an imaging device includes a lens barrel including a body and a plurality of focusing fins extending from the body. The imaging device further includes a lens system disposed within the lens barrel and configured to receive electromagnetic radiation and direct the electromagnetic radiation. The imaging device further includes a detector array including a plurality of detectors. Each of the plurality of detectors is configured to receive the electromagnetic radiation from the lens system and generate an image based on the electromagnetic radiation. Related methods and systems are also provided.

Abstract: A connector assembly is configured to fluidly and removably connect a first set of microtubes to a second set of microtubes of a microfluidic device. The connector assembly provides multiple points of contact to the microtubes to provide a secure connection between the connector assembly and the microtubes. A single gasket provides a securely aligned connection between microtubes.

Abstract: A clocked storage element comprises a first latch having an input data node, a clock input node and a first latch output data node, and a second latch having an input connected to the first latch output data node, a clock input node and a second latch output data node. The first and second latches can have a clocked pull-up current path consisting of two p-channel transistors between their respective output data nodes and the VDD supply line, and a clocked pull-down current path consisting of two n-channel transistors between their respective output data nodes and the VSS supply line.

Abstract: An NVM algorithm generator that evaluates a Liberty file characterizing an NVM module and a memory view of the NVM module that identifies ports and associated operations of the NVM module to generate a control algorithm. The control algorithm includes a read algorithm that includes an order of operations for assigning values to ports of the NVM module to assert a read condition of a strobe port, executing a memory read on the NVM module and setting values to the ports on the NVM module to assert a complement of a program condition. The control algorithm also includes a program algorithm that includes an order of operations for assigning values to ports of the NVM module to assert the program condition of the strobe port, executing a memory write and setting values to the ports on the NVM module to assert the complement of the program condition.