Abstract: In an example embodiment, a system may facilitate a root cause analysis associated with one or more computer applications. The system may receive a global time reference at the one or more computer applications. Each computer application may have a corresponding local time reference. Each computer application may synchronize its local time reference with the global time reference. The system may monitor at least one computer instructions of the computer applications with respect to the corresponding local time reference. The system may retrieve information associated with the at least one computer instruction. The system may forward at least a portion of the retrieved computer instruction information to a validation engine. The system may facilitate the root cause analysis using the at least a portion of the retrieved computer instruction information.

Abstract: A netlist of a multiple voltage circuit design having a plurality of power domains is established, then inter-power domain (IPD) paths traversing the circuit design are identified, according to whether they traverse multi-supply elements, or are clock paths capturing such a path. The netlist is then pruned to disable or remove cells or stages not traversed by an IPD path. A timing analyzer conducts a multi-domain timing analysis of the IPD timing paths in the pruned IPD netlist. Thereby, the circuit design is thoroughly tested according to the applicable ranges of voltage conditions without excessive runtime.

Abstract: A system and method to identify a call end associated with a problem that caused failure of an internet protocol-based call. The method includes accessing a first call detail record (CDR) set including at least one CDR associated with a first call end of the failed call, determining from the first CDR set indicators of failure attribution of the failed call, determining whether fault for failure of the failed call is attributed to the first call end based on the indicators of failure attribution; outputting an indication that the fault is attributed to the first call end if it was determined that the fault is attributed to the first call end, and outputting the indication to indicate the first call end is acquitted of the fault if it was determined the fault is not attributed to the first call end.

Abstract: The methods described herein allow for the classification of patients into groups for receiving optimized radiation treatment based on patient specific biomarker signature. The biomarker signature includes markers that have been shown to correlate with TGF-B expression and to be associated with tumor aggressiveness, radioresistance and poor prognosis. The markers play a key role in the epithelial-mesenchymal transition. The methods described herein provide the dual benefits of anti-tumor efficacy plus normal tissue protection when combining TGF-B inhibitors with ionizing radiation to treat cancer patients.

Abstract: An apparatus and method are used for three-dimensional sensing with a time-of-flight lidar sensor having a single emitter sensing in one dimension, at least one photodetector, and a mechanical means of scanning in two dimensions said emitter and at least one photodetector. The external case of the lidar is preferably static, and only internal components involve mechanical motion. In a preferred embodiment of said lidar when operated in the infrared, said external static case has a window that is visually opaque and essentially transparent to infrared radiation.

Abstract: Systems and methods for managing regulatory information. The system comprises a submission controller, a registration controller and a submission archive controller. The submission controller may manage a submission structure, and allow users to search for documents in a content management system and add the documents to the submission structure. The registration controller may manage product registration information and health authority interactions globally, and capture, view and take actions upon product registrations. The submission archive controller may allow users to access a complete history of regulatory submissions and correspondence globally, with an easy to use interface. The three controllers reside in a single system that allows them to interact seamlessly with each other.

Abstract: Method and systems of controlling detonation of a plurality of explosive charges. A controller has a magneto-inductive transmitter to transmit a magneto-inductive signal to a plurality of detonators, each having a receiver to receive the magneto-inductive signal and a respective firing delay time. The method includes, at each of the plurality of detonators, receiving, via the magneto-inductive signal from the magneto-inductive transmitter, a time sync signal; synchronizing a local clock in the detonator based on the time sync signal; receiving, via the magneto-inductive signal from the magneto-inductive transmitter, a firing code; waiting the respective firing delay time from receipt of the firing code, wherein the waiting is clocked by the local clock; and after expiry of the respective firing delay time, triggering a respective explosive associated with the detonator.

Abstract: A computer program configured as a server includes a first interface for communication between the network node and a computer device, a second interface for communication between the network node and the monitoring service, a third interface for communication between the network node and the home gateway, and a database to store configuration data of the home gateway. The server includes logic to maintain the configuration data in the database via communications using the third interface which include messages identifying sensing devices connected to the home gateway. The server includes logic to receive an activation request from the computing device via the first interface, and in response to the activation request, execute a protocol via the second interface to create a user record using the configuration data. The server includes logic to verify a connection between the home gateway and the user record via the third interface.

Abstract: A method of performing a medical procedure, includes providing a catheter including a first lumen in fluid communication with a first distal opening and a second lumen in fluid communication with a second distal opening, advancing a distal end of a first intra-catheter stiffener element through the first lumen and out of the first distal opening, coupling the first intra-catheter stiffener element to the catheter, advancing a distal end of a second intra-catheter stiffener element through the second lumen and out of the second distal opening, coupling the second intra-catheter stiffener element to the catheter, and advancing the catheter into a patient.

Abstract: A wellhead assembly is disclosed which has a gas flow control valve with a tubular inlet into which a fluid from a well tube flows, and a gas flow line through which the fluid flows out from the gas flow control valve. An inlet tube has a first end operably coupled to the well tube, and a second coupled to the inlet of the valve. The inlet has a first groove formed on a surface thereof, and the inlet tube has a second groove formed on a surface thereof. A split lock ring is used which partially rests in, and which is substantially fully compressed into, one of the grooves, when the inlet tube is telescopically coupled to the inlet. The lock ring engages with the other one of the grooves as the two grooves become axially aligned during coupling, to lock the inlet tube to the inlet while permitting rotational movement of the inlet tube relative to the inlet.

Abstract: A system according to certain aspects may include a client computing device including: a database application configured to output a database file in a primary storage device(s), the database application outputting the database file as a series of application-level blocks; and a data agent configured to divide the database file into a plurality of first blocks having a first granularity larger than a second granularity of the application-level blocks such that each of the first blocks spans a plurality of the application-level blocks. The system may include a secondary storage controller computer(s) configured to: in response to instructions to create a secondary copy of the database file: copy the plurality of first blocks to a secondary storage device(s) to create a secondary copy of the database file; and create a table that provides a mapping between the copied plurality of first blocks and corresponding locations on the secondary storage device(s).

Abstract: Disclosed are methods, systems, and articles of manufacture for implementing deadlock detection with formal verification techniques in an electronic design. These techniques identify one or more inputs that include at least an initial state of an electronic design and identify at least one deadlock candidate by sweeping at least a portion of a state space of the electronic design with formal verification techniques. These techniques then determine whether the at least one deadlock candidate is a real deadlock by using a second formal search with the formal verification techniques.

Abstract: Techniques for enabling user search of content stored in a file archive include providing a search interface comprising a search rules portion and an action rules portion, receiving a file archive search criterion comprising at least one search rule, and searching the file archive using the search criterion. The techniques also include generating a set of files filtered using the search criterion and performing an action specified in the action rules portion on a file included in the set of files.

Abstract: A computing device (e.g., an FPGA or integrated circuit) processes an incoming packet comprising data to compute a Galois hash. The computing device includes a plurality of circuits, each circuit providing a respective result used to determine the Galois hash, and each circuit including: a first multiplier configured to receive a portion of the data; a first exclusive-OR gate configured to receive an output of the first multiplier as a first input, and to provide the respective result; and a second multiplier configured to receive an output of the first exclusive-OR gate, wherein the first exclusive-OR gate is further configured to receive an output of the second multiplier as a second input. In one embodiment, the computing device further comprises a second exclusive-OR gate configured to output the Galois hash, wherein each respective result is provided as an input to the second exclusive-OR gate.

Abstract: An active exhalation valve for use with a ventilator to control flow of patient exhaled gases. The valve includes a patient circuit connection port, a patient connection port, an exhaled gas port, a pilot pressure port, and a valve seat. The valve further has a movable poppet with inner and outer bellows members and a bellows poppet face. An activation pressure applied to the pilot pressure port extends the bellows members to move the poppet face into engagement with the valve seat and restrict flow of patient exhaled gases to the exhaled gas port, and the reduction of the activation pressure allows the bellows members to move the poppet face away from the valve seat and out of engagement with the valve seat to permit flow of patient exhaled gases to the exhaled gas port, thereby controlling the flow of patient exhaled gases from the valve.

Abstract: Systems and methods for displaying an individual profile page in an organization directory. The method comprises storing the individual's name and start date with the organization in a database; receiving a request for displaying the individual profile page; comparing the individual's start date with the current date to determine the individual's tenure with the organization; and determining using a first type of icon to represent a first period of time and a second type of icon to represent a second period of time.

Abstract: The present invention provides for novel methods and compositions for nucleic acid sequence detection. Unique, identifying cleavage fragments from probes, bound to target nucleic acids, are produced during PCR by the 5?-nuclease activity of the polymerase. The identity of the targets can be determined by identifying the unique cleavage fragments.

Abstract: An oven for baking a food product includes a housing having a ceiling, a floor, first and second opposing side walls, at least one internal heating zone defined by the ceiling, the floor and the first and second opposing side walls, and at least one heating source for providing heat to the at least one internal heating zone. The ceiling is formed of carbon steel. At least a surface of the ceiling facing the at least one internal heating zone is formed as a high emissivity chemical conversion coating.

Abstract: This disclosure relates to a system and method for determining vehicle operator preparedness for vehicles that support both autonomous operation and manual operation. The system includes sensors configured to generate output signals conveying information related to vehicles and their operation. During autonomous vehicle operation, the system gauges the level of responsiveness of an individual vehicle operator through challenges and corresponding responses. Based on the level of responsiveness, a preparedness metric is determined for each vehicle operator individually.

Abstract: An intravascular sensor delivery device for measuring a physiological parameter of a patient, such as blood pressure, within a vascular structure or passage. In some embodiments, the device can be used to measure the pressure gradient across a stenotic lesion or heart valve. For example, such a device may be used to measure fractional flow reserve (FFR) across a stenotic lesion in order to assess the severity of the lesion. The sensor delivery device has a distal sleeve configured to pass or slide over a standard medical guidewire. Some distance back from the sensor and distal sleeve, the device separates from the guidewire to permit independent control of the sensor delivery device and the guidewire. The sensor delivery device can be sized to pass over different sizes of guidewires to enable usage in coronary and peripheral arteries, for example.