Abstract: A machine to cover articles with flexible plastic material sheets. The machine includes an assembly for heat-sealing and cutting the sheets which cooperates with a work surface. The assembly includes a first and a second element, of which at least the first element is movable with respect to the other, and the two elements being arranged on opposite sides of the work surface. The first element includes a cutting and sealing blade having an electric current which passes through it and the second element including a cutting and sealing counter blade. Operation levers are provided to move the cutting and sealing blade from a rest position to a work position where the cutting and sealing blade engages the cutting and sealing counter blade. The first element and the levers belong to a unit connected to the work surface in a removable manner. The unit also includes elastic portions for holding the blade at a rest position.

Abstract: A method for applying a pattern (21, 57) of granular material (12, 12b, 12c, 12d) on a receiving surface (13), comprising in sequence associating said granular material (12, 12b, 12c, 12d) with a transferring surface (3) together with a liquid aggregating phase (9, 20) and according a prefiguration (10, 10b, 18, 56) of said pattern; facing said transferring surface (3) carrying said granular material (12, 12b, 12c, 12d) and said liquid phase (9, 20) to said receiving surface (13) in a transferring zone (15, 45); the method further comprises heating at least one portion of said liquid phase (9, 20) in said transferring zone (15) in order to detach from said transferring surface (3) said granular material (12, 12b, 12c, 12d) and applying the latter on said receiving surface (13).

Abstract: The present invention relates to a process for the preparation of carvedilol as well as of the optically active R and S enantiomers thereof and of mixtures of these enantiomers and, more particularly, relates to an improved process for the preparation of carvedilol and its enantiomers characterized by the use of ethyl acetate as reaction solvent.

Abstract: A process and new oxazolinic intermediates for the preparation of 4-(8-chloro-5,6-dihydro-11H-benzo-[5,6]-clohepta-[1,2-b]-pyridin-11-ylide-ne)-1-piperidinecarboxylic acid ethyl ester (loratadine) is described. The process starts from 2-(4,4-dimethyl-4,5-dihydrooxazol-2-yl)-3-methyl-pyridine, a new intermediate to obtain loratadine. 2-(4,4-dimethyl-4,5-dihydro-oxazol-2-yl)-3-methyl-pyridine is condensed with 3-chloro-benzyl-chloride and the resultant product is treated with Grignard reagent of 4-chloro-N-methyl-piperidine. [3-(2-(3-chloro-phenyl)-ethyl]-pyridin-2-yl-]-1-(methyl-piperidin-4-yl)-methanone is obtained for subsequent hydrolysis. Starting from this last compound it is possible to obtain loratadine with known methods.

Abstract: Stable compositions containing gabapentin compositions, methods of preparing such compositions, and methods of using such compositions.

Abstract: A method of coating a endovascular device that includes coating of a tubular body's surface by at least a thin layer (s) of a inert and biocompatible titanium based material. This method is performed by the following steps in succession: Deposition of a first Titanium layer (21). First nitrogen treatment of said first titanium layer (21) by transmission of high ionic currents on the substrate (Closed Field UnBalanced Magnetron Sputter Ion Plating) to obtain the transformation of at least a part of said first titanium layer (21) in a first layer of titanium nitride ceramic coating (210). Deposition on this said first layer of titanium nitride ceramic coating (210) of a second titanium layer (22). Second nitrogen treatment of said second titanium layer (22) by transmission of high ionic currents on the substrate (Closed Field UnBalanced Magnetron Sputter Ion Plating) to obtain the transformation of at least a part of said second titanium layer (22) in a second layer of titanium nitride ceramic coating (220).

Abstract: A process and new oxazolinic intermediates for the preparation of 4-(8-chloro-5,6-dihydro-11H-benzo-[5,6]-cyclohepta-[1,2-b]-pyridin-11-ylidene)-1-piperidinecarboxylic acid ethyl ester (loratadine) is described. The process starts from 2-(4,4-dimethyl-4,5-dihydrooxazol-2-yl)-3-methyl-pyridine, a new intermediate to obtain loratadine. 2-(4,4-dimethyl-4, 5-dihydrooxazol-2-yl)-3-methyl-pyridine is condensed with 3-chloro-benzyl-chloride and the resultant product is treated with Grignard reagent of 4-chloro-N-methyl-piperidine. [3-(2-(3-chloro-phenyl)-ethyl]-pyridin-2-yl]-1-(methyl-piperidin-4-yl)-methanone is obtained for subsequent hydrolysis. Starting from this last compound it is possible to obtain loratadine with known methods.

Abstract: A method and system for automatically extracting relations between concepts included in electronic text is described. Aspects the exemplary embodiment include a semantic network comprising a plurality of lemmas that are grouped into synsets representing concepts, each of the synsets having a corresponding sense, and a plurality of links connected between the synsets that represent semantic relations between the synsets.

Abstract: The present invention relates to a process for the preparation of gabapentin and, more particularly, it relates to a precipitation process of gabapentin by acidification of an aqueous solution deriving from the Hofmann rearrangement of 1,1-cyclohexanediacetic acid monoamide.

Abstract: A process for the preparation of gabapentin which comprises the passage of a gabapentin inorganic salt through a strong cationic ionic exchange resin, the elution of gabapentin fixed on the column, the concentration of the resultant solution and the cristallization from organic solvent, characterized in that the elution of gabapentin fixed on the column is carried out by using an ammonia and alkaline hydroxide aqueous solution, is described.

Abstract: An obstacle detection system, particularly for assisting car parking that comprises a control unit and a plurality of sensors, which comprise emitters-receivers for emitting an ultrasonic signal and for receiving an echo signal reflected by at least one obstacle and an evaluator for the parametric evaluation of the received echo signals, the evaluator comprising a polling module suitable to determine, for each sensing, the number of times for which the received signals are repeated and to reject the signals that are repeated for a number of times that is lower than a preset number.

Abstract: A process for the in situ preparation of chiral compounds derived from oxazaborolidine-borane complexes, wherein a metal borohydride, a Lewis base and an inorganic acid ester are brought together and an optically active amino alcohol and optionally a halide are then added. The compound obtained is a complex that is useful as a catalyst in asymmetric reduction reactions. The reaction is performed by adding the substance to be reduced, particularly prochiral ketones or ether oximes, in order to synthesize chiral alcohols or chiral amines.

Abstract: A process for the purification of gabapentin by treatment of a crude aqueous gabapentin hydrochloride solution with a strong cationic ion exchange resin.

Abstract: A process for the preparation of gabapentin comprising the passage of a salt of the same through a ionic exchange resin of strong cationic type, the elution of the gabapentin which has fixed onto the column and the crystallization from organic solvent, characterized in that the resin is regenerated by using a mineral acid in a molar quantity between 50 and 90%, is described.

Abstract: An obstacle detection method and system, particularly for car parking systems comprising emitting ultrasound signals at a plurality of sensors, receiving echo signals returned by at least one obstacle, performing a parametric evaluation of the received signals, determining, for each sensor, the distance between the sensor and an obstacle detected by it, associating with each sensor a value of the distance from the obstacle detected by it; determining a value corresponding to the minimum detected distance and replacing it with the sum value between a minimum distance and a priority threshold value; assigning to the sensor that detected the minimum distance a priority status; and defining a sensor polling cycle that polls more frequently a priority status sensor than non-prioritized sensors.

Abstract: Cooling assembly for vehicles, comprising a radiator including two collecting tanks made of plastic material, an element fastened to the radiator, and fastening means for the mutual fastening of the element and of the radiator, including two U-shaped seats on each of said collecting tanks and two pairs of engagement members fastened to said element. Each of said engagement members comprises a pivot formation with a cylindrical outer surface having circular section and each of said seats has an elastically deformable snap-on engagement surface having semi-cylindrical shape with circular section able to receive said pivot formation in snap-on engagement.

Abstract: Stable compositions containing gabapentin compositions, methods of preparing such compositions, and methods of using such compositions.

Abstract: An apparatus for distributing powders on a support in a predetermined pattern, includes: a belt conveyor (2) for transporting the support (3); a head for applying the powders (1), located above the conveyor (2), which head (1) includes a ring-wound closed continuous belt (4) exhibiting a plurality of perforations arranged according to a predetermined pattern, the perforations being of a size which enables passage of predetermined quantities of powders; a mechanism for controlling a supply and delivery of powders through the perforations and for keeping the continuous belt (4) clean. The head also includes a mechanism for controlling a movement of the continuous belt (4) in synchrony with a movement of the conveyor (2).

Abstract: A structure for presses includes: a resistant structure having at least one resistance element having a flat annular element internally of which and in diametrically opposite positions two facing surfaces are arranged, between which facing surfaces at least one tool can be inserted, for exerting a pressing action and compressing between two bodies, the two facing surfaces receiving equal and opposite reactions to the pressing action. Cuts at ends of the facing surfaces involve a total thickness of the facing surface. Each cut includes a first tract parallel to a pressing direction and a second circular part; the circular second part constituting a snug seating for discs. Interpositioning elements are provided for being interpositioned between ends of the facing surfaces so that two resultants, parallel to the pressing direction, of action exerted on each facing surface are located externally to centers of corresponding circular second parts.