Abstract: The present disclosure provides an operation method of a prediction system of significant congenital heart disease in infants in infants, which includes steps as follows. The continuous wavelet transformation is performed on the electrocardiogram to obtain the processed electrocardiogram; the processed electrocardiogram is oversampled to obtain multiple electrocardiogram segments; the transfer learning through multiple pre-trained models based on the multiple electrocardiogram segments is used to establish a significant congenital heart disease model.

Abstract: A process for preparing a modified heat-treated platelet pellet lysate, said process comprising the steps of: a) Providing a platelet pellet lysate, b) Heat-treating the platelet pellet lysate at a temperature of 55° C. to 65° C. during 20 to 40 minutes, c) Purifying the heat-treated platelet pellet lysate of step b) so as to obtain a modified heat treated platelet pellet lysate having a total protein content of less than 70% of the total protein content of the platelet pellet lysate of step a).

Abstract: A method of preparing polylactic acid (PLA) microsphere and polylactic-co-glycolic acid (PLGA) microsphere is provided, including the following steps. A first solution is provided, including polylactic acid or polylactic-co-glycolic acid and an organic solvent. A second solution is provided, including polyvinyl alcohol, sodium carboxymethyl cellulose and an aqueous solution. The first solution is added to the second solution and, at the same time, the second solution is agitated until polylactic acid is solidified to form a plurality of polylactic acid microspheres, or until polylactic-co-glycolic acid is solidified to form a plurality of polylactic-co-glycolic acid microspheres. The polylactic acid microspheres or polylactic-co-glycolic acid microspheres are collected.

Abstract: The present disclosure provides an operating method of an identifying and quantizing system, which includes steps as follows. The T2 weighted image is split into a first group of two-dimensional images; the first group of two-dimensional images is inputted into the mask R-CNN model to obtain the first group of two-dimensional parenchymal brain images; a first group of two-dimensional parenchymal brain images is used to form T2 weighted parenchymal brain images; T2 weighted parenchymal brain image is pre-processed to obtain a pre-processed T2 weighted parenchymal brain image; a three-dimensional convolutional neural network model is used to segment and quantize the brain edema area in the pre-processed T2 weighted parenchymal brain image.

Abstract: The present disclosure provides an operation method of a PET (positron emission tomography) quantitative localization system, which includes steps as follows. The PET image and the MRI (magnetic resonance imaging) of the patient are acquired; the nonlinear deformation is performed on the MRI and the T1 template to generate deformation information parameters; the AAL (automated anatomical labeling) atlas is deformed to an individual brain space of the patient, so as to generate an individual brain space AAL atlas, where the AAL atlas and the T1 template are in a same space; lateralization indexes of the ROIs of the individual brain space AAL atlas corresponding to the PET image normalized through the gray-scale intensity are calculated; the lateralization indexes are inputted into one or more machine learning models to analyze the result of determining a target.

Abstract: The present disclosure provides an operating method of a brain imaging neurological abnormality prediction system, which includes steps as follows. The T1-weighted image and the diffusion-weighted image of the patient are acquired; the image process is performed on the T1-weighted image and the diffusion-weighted image to obtain a smoothed brain standard space infarction image; the smoothed brain standard space infarction image is multiplied by and a weighted image for a post-processing to obtain a post-weight image; the post-weight image is inputted to the deep learning cross validation classification model of transfer learning to predict whether the neurological abnormality occurs within a predetermined period after the patient's brain disease.

Abstract: The present invention relates to an extract of Salvia miltiorrhiza and/or an extract of Poncirus trifoliata for inhibiting obesity. In particular, the extract of Salvia miltiorrhiza and/or the extract of Poncirus trifoliata is/are prepared by solvent or supercritical fluid extraction. Specifically, the extract of Salvia miltiorrhiza and/or the extract of Poncirus trifoliata is/are effective in inhibiting lipid accumulation in adipocytes and slowing down body weight gain of the subject. More specifically, the extract of Salvia miltiorrhiza and/or the extract of Poncirus trifoliata can be used in combination with an extract of Curcuma longa, which exhibit improved effects in inhibiting lipid accumulation in adipocytes and slowing down body weight gain of the subject.

Abstract: An equipment for monitoring physiological status of a user includes a sound detection unit, a chest detection unit, an abdomen detection unit, and a control unit. The sound detection unit is configured to detect sound of breath and to generate a sound detection signal based on the sound of breath. The chest detection unit is configured to detect a parameter related to movement of a chest and to generate a chest detection signal based on the detection. The abdomen detection unit is configured to detect a parameter related to movement of an abdomen and to generate an abdomen detection signal based on the detection. The control unit is electrically connected to the sound detection unit, the chest detection unit, and the abdomen detection unit and is configured to determine a breathing status of a user based on the sound detection signal, the chest detection signal, and the abdomen detection signal.

Abstract: An evaluation method of sleep quality and a computing apparatus related to sleep quality are provided. In the evaluation method, sensing data is obtained. The sensing data is generated based on a radar echo. The sensing data is transformed into feature data. The feature data includes a statistic of a plurality of feature points on a waveform of the radar echo. Sleep quality information is determined according to the feature data. Accordingly, sleep quality may be evaluated through non-touch sensing.

Abstract: A device includes an angiography module, a phototherapy module, a carrier including an optical filter and accommodating the angiography module and the phototherapy module, and a control unit controlling operation of the angiography module and the phototherapy module. The angiography module includes infrared LEDs emitting infrared light through the optical filter to irradiate a limb of a subject, and an infrared sensor sensing a part of the infrared light reflected off the limb to generate a result, based on which the control unit generates an angiogram. The phototherapy module emits infrared light through the optical filter to irradiate the limb for phototherapy.

Abstract: The present disclosure relates to a biodegradable and thermosensitive hydrogel composition comprising a diblock PLGA-PEG copolymer and a triblock PLGA-PEG-PLGA copolymer. A method for treating or alleviating one or more symptoms of a disease and a method for delivering an active agent are also provided.

Abstract: A device includes an angiography module, a phototherapy module, a carrier including an optical filter and accommodating the angiography module and the phototherapy module, and a control unit controlling operation of the angiography module and the phototherapy module. The angiography module includes infrared LEDs emitting infrared light through the optical filter to irradiate a limb of a subject, and an infrared sensor sensing a part of the infrared light reflected off the limb to generate a result, based on which the control unit generates an angiogram. The phototherapy module emits infrared light through the optical filter to irradiate the limb for phototherapy.

Abstract: An operating method of a ketogenic dietary evaluation system includes steps as follows. The electroencephalogram data of a responder group and the electroencephalogram data of a non-responder group are preloaded, in which each electroencephalogram datum includes electroencephalograms of channels. The electroencephalograms of the channels are preprocessed to obtain the preprocessed electroencephalograms of the channels. A connectivity matrix is obtained on a basis of the phase synchronization between each two of the preprocessed electroencephalograms of the channels. The connectivity matrix is sampled and analyzed through different frequency bands and different proportion threshold values to obtain graphical parameters. A predictive model is established on a basis of a reduction rate of a predetermined event of the responder group, a reduction rate of the predetermined event of the non-responder group and the parameters.

Abstract: The invention relates to anti-EGF like domain multiple 6 antibody (anti-EGFL6 antibody) and cancer detection (or diagnosis) and treatment using the anti-EGFL6 antibody. The present invention creates anti-EGFL6 antibodies, particularly, a single-chain antibody fragments (scFv) and humanized antibody, which have ability in binding to EGFL6 and in inhibiting angiogenesis and cancer cell growth.

Abstract: Disclosed herein are hydroxamic acid compounds. Also disclosed is a method of using the hydroxamic acid compounds for treating a condition associated with histone deacetylase 6.

Abstract: A device includes an angiography module, a phototherapy module, a carrier including an optical filter and accommodating the angiography module and the phototherapy module, and a control unit controlling operation of the angiography module and the phototherapy module. The angiography module includes infrared LEDs emitting infrared light through the optical filter to irradiate a limb of a subject, and an infrared sensor sensing a part of the infrared light reflected off the limb to generate a result, based on which the control unit generates an angiogram. The phototherapy module emits infrared light through the optical filter to irradiate the limb for phototherapy.

Abstract: The present disclosure provides an operating method of a dopamine transporter check system, and the operation method includes steps as follows. A scan image of a subject's brain is obtained from a scan machine, and the scan image is a three-dimensional image. The scan image is aligned to a standard brain space to obtain a standardized scan image. Intensity normalization is performed on the standardized scan image. The standardized scan image after the intensity normalization is converted into a two-dimensional image. A plurality of image data are got from at least one region of interest in the two-dimensional image, and the at least one region of interest includes a left caudate, a left putamen, a right caudate and a right putamen. A dopamine neuron loss degree measurement and evaluation model based on the image data is established through a transfer learning.

Abstract: The present disclosure provides an operating method of a system for analyzing brain tissue based on computerized tomographic imaging, and the operation method includes steps as follows. A computed tomography image of a subject is aligned to a predetermined standard brain space image, to obtain a first normalized test computed tomography image. A voxel contrast of the first normalized test computed tomography image is enhanced to obtain an enhanced first normalized test computed tomography image. The enhanced first normalized test computed tomography image is aligned to an average computed tomographic image of a control group to obtain a second normalized test computed tomography image. An analysis based on the second normalized test computed tomography image and a plurality of computerized tomographic images of the control group is performed to obtain a t-score map.

Abstract: The invention relates to the use of Indoline derivatives, and their effective dose in the prevention and/or treatment of fibrosis diseases. The compound can effectively prevent and/or treat a fibrosis disease without cytotoxicity or genotoxicity.

Abstract: A medical image processing system includes a memory and a processor coupled to each other. The processor accesses and executes instructions which memory stores to perform the following: obtaining a plurality of brain MR images corresponding to a subject, wherein the brain MR images corresponds to a subject brain space; accessing a DBS targets atlas corresponding to a specific stimulation area; transforming the DBS targets atlas from a MNI brain space to the subject brain space based on a DARTEL algorithm; marking at least one coordinate having a largest Voxel value in the brain MR images based on the transformed DBS targets atlas; and storing the brain MR images being targeted with the at least one coordinate into a predetermined format corresponding to a guiding device so that the guiding device displays the brain MR images being targeted with the at least one coordinate for guidance in DBS procedure.