Patents Assigned to TCI CO., LTD.
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Patent number: 11471395Abstract: A method for preventing aging of a subject in need thereof includes administering to the subject a composition including a bioactive compound. The bioactive compound is a peptide, and includes at least one amino acid sequence as set forth in SEQ ID NO: 1 to SEQ ID NO: 6. Each of the amino acid sequence is a peptide of fish skin. The composition has anti-aging and cellular health maintaining capabilities. In addition, the composition can also be used for increasing collagen content, improving skin collagen density, improving skin moisture, minimizing skin pores, reducing wrinkles or achieving a combination of these effects.Type: GrantFiled: November 17, 2020Date of Patent: October 18, 2022Assignee: TCI CO., LTD.Inventors: Yung-Hsiang Lin, Yu-Ling Wang
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Patent number: 11406673Abstract: A method of sobering up, comprising administering composition comprising an effective amount of Bacillus coagulans TCI711. The Bacillus coagulans TCI711 is deposited in Consortium Food Industry Research and Development Institute (Deposit number: BCRC910807) and German Microbial and Cell Culture Collection Center (DSMZ-DEUTSCHE SAMMLUNG VON MIKROORGANISMEN UND ZELLKULTUREN GmbH) (Deposit number: DSM33163).Type: GrantFiled: August 14, 2020Date of Patent: August 9, 2022Assignee: TCI CO., LTD.Inventors: Yu-Kai Chiu, Yung-Hsiang Lin
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Patent number: 11400138Abstract: A method for improving a skin condition of a subject in need thereof includes administering to the subject a composition including a bioactive compound. The bioactive compound is a peptide, and includes at least one amino acid sequence as set forth in SEQ ID NO: 1 to SEQ ID NO: 11. Each of the amino acid sequence is a peptide of fish skin.Type: GrantFiled: November 17, 2020Date of Patent: August 2, 2022Assignee: TCI CO., LTD.Inventors: Yung-Hsiang Lin, Yu-Ling Wang
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Patent number: 11389501Abstract: A method for treating eye inflammation by using an anti-inflammatory composition is provided. The bioactive compound in the anti-inflammatory composition is a peptide having an amino acid sequence as set forth in SEQ ID NO.: 1. The amino acid sequence is a peptide fragment derived from cowhide. The composition may be administered to the eye of a human subject for reducing the expression of vascular endothelial growth factor A (VEGFA) gene, interleukin-1 beta (IL-1?) gene, and/or interleukin-8 (IL-8) gene.Type: GrantFiled: May 25, 2021Date of Patent: July 19, 2022Assignee: TCI CO., LTD.Inventors: Yung-Hsiang Lin, Yu-Ling Wang
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Patent number: 11344587Abstract: Provided is a method of improving urogenital health, including administering to a subject a composition including an effective amount of a Lactobacillus johnsonii strain deposited under the accession number of DSM 33288 or a metabolite thereof. The Lactobacillus johnsonii strain, which is a probiotic, and metabolites thereof inhibit the growth of common pathogenic bacteria and fungi causing genitourinary tract infections, thereby reducing the risk of genitourinary tract infections or alleviating symptoms thereof. Also provided is a composition for improving urogenital health which includes the Lactobacillus johnsonii strain.Type: GrantFiled: November 22, 2019Date of Patent: May 31, 2022Assignee: TCI CO., LTD.Inventors: Yung-Hsiang Lin, Chu-Han Huang, Cheng-Yu Ho
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Patent number: 11324782Abstract: The present invention provides a use of herb ferment for preparing a composition for preventing and/or treating obesity; wherein, the herb is Abelmoschus esculentus. The fermentation process of the present invention can enhance the content of total polysaccharide in the herb ferment, and effectively increase the amylase inhibition rate and the glucosidase inhibition rate of the herb ferment to effectively inhibit the decomposition and absorption of starch and glucoside. The herb ferment of the present invention can also effectively reduce the blood glucose of subjects after meals, and can effectively reduce the body weight, BMI value, waist circumference, visceral fat, average whole body fat percentage, and average body fat percentage, and can be effectively used to regulate blood glucose and blood lipids for weight loss. The herb ferment is prepared by fermenting the herb extract to yeast and lactic acid bacteria.Type: GrantFiled: December 26, 2019Date of Patent: May 10, 2022Assignee: TCI CO., LTD.Inventors: Yung-Hsiang Lin, Wei-Hsiu Chuang
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Publication number: 20220125708Abstract: Provided is a method for skin conditioning comprising administering to a subject in need thereof a composition comprising a Dan Feng peony extract, where the Dan Feng peony extract is extracted from flowers of Dan Feng peony. The Dan Feng peony extract is used to increase the production of hyaluronic acid, maintain the structure of skin keratinocytes, and regulate the moisture content of skin cells.Type: ApplicationFiled: October 26, 2021Publication date: April 28, 2022Applicant: TCI CO., LTD.Inventors: YUNG-HSIANG LIN, WEI-CHUN LEE
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Patent number: 11304892Abstract: Alteromonas macleodii Dow02-2 is provided, wherein the Alteromonas macleodii Dow02-2 was deposited at German Collection of Microorganisms and Cell Cultures (Deutsche Sammlung von Mikroorganismen and Zellkulturen, DSMZ) under the accession number DSM33380, and its metabolites comprise 2-hydroxy-3-methylbutyric acid. A method for providing 2-hydroxy-3-methylbutyric acid is also provided, wherein the method comprises isolating the 2-hydroxy-3-methylbutyric acid from metabolites of Alteromonas macleodii Dow02-2 of biologically pure culture. A method for at least one of increasing expression of TGM1 gene, increasing expression of KRT1 gene, increasing expression of KRT10 gene, increasing expression of KRT14 gene, increasing expression of FLG gene, increasing expression of GBA gene, and increasing expression of HAS3 gene is also provided, wherein the method comprises administering to a subject in need thereof an effective amount of 2-hydroxy-3-methylbutyric acid.Type: GrantFiled: December 19, 2019Date of Patent: April 19, 2022Assignee: TCI Co., Ltd.Inventors: Chu-Han Huang, Huan-You Lin, Cheng-Yu Ho, Yung-Hsiang Lin
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Patent number: 11278582Abstract: Provided is a composition for reducing the fat content of fat-producing cells and applications thereof. The composition includes plant extracts such as a blueberry extract and a black tea extract.Type: GrantFiled: April 3, 2018Date of Patent: March 22, 2022Assignee: TCI CO., LTD.Inventors: Yung-Hsiang Lin, I-Hui Chen, Kai-Wen Kan, Fu Chen Liu, Ciao-Ting Chen
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Patent number: 11273189Abstract: Lactobacillus plantarum TCI378 is provided. The Lactobacillus plantarum TCI378 was deposited at German Collection of Microorganisms and Cell Cultures (Deutsche Sammlung von Mikroorganismen and Zellkulturen, DSMZ) under the accession number DSM 32451. A method for losing fat and/or improving gastrointestinal functions is also provided. The method comprises administering to a subject in need an effective amount of a composition, wherein the composition comprises Lactobacillus plantarum TCI378 and/or its metabolites.Type: GrantFiled: April 21, 2020Date of Patent: March 15, 2022Assignee: TCI CO., LTDInventors: Yung-Hsiang Lin, Chu-Han Huang, Cheng-Yu Ho
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Patent number: 11207359Abstract: The present invention provides a cholesterol reducing probiotic strain, composition thereof and use thereof. The probiotic strain is Lactobacillus plantarum TCI507, which itself and its metabolites can effectively reduce the cholesterol content, enhance the gene expression level of SCARB1, APOA1, and LDLR to promote the effect of cholesterol metabolism, and can effectively reduce the total cholesterol and the low-density lipoprotein in human blood.Type: GrantFiled: August 2, 2019Date of Patent: December 28, 2021Assignee: TCI CO., LTD.Inventor: Yung-Hsiang Lin
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Patent number: 11202812Abstract: The present invention provides a method of reducing body fat, comprising administering a composition comprising an effective amount of Lactobacillus paracasei or a metabolite thereof to a subject in need thereof. The Lactobacillus paracasei or the metabolite thereof can effectively convert the fatty acid into conjugated linoleic acid, inhibit the accumulation of fat and promote the decomposition of fat in fat cells, and can effectively reduce the percentage of body fat, waist circumference, and hip circumference, and simultaneously increase the muscle mass of the subject.Type: GrantFiled: December 31, 2019Date of Patent: December 21, 2021Assignee: TCI CO., LTD.Inventors: Yung-Hsiang Lin, Chu-Han Huang, Cheng-Yu Ho
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Patent number: 11173107Abstract: A method for at least one of whitening skin, improving skin condition, protecting skin, and treating skin disease is provided, wherein the method comprises administering to a subject in need an effective amount of a Pyrenaria buisanensis extract. A method for at least one of preventing cardiovascular disease, treating cardiovascular disease, preventing diabetes, treating diabetes, preventing neurodegenerative disease, and treating neurodegenerative disease is also provided, wherein the method comprises administering to a subject in need an effective amount of a Pyrenaria buisanensis extract.Type: GrantFiled: October 16, 2018Date of Patent: November 16, 2021Assignee: TCI CO., LTD.Inventors: Yung-Hsiang Lin, Yu-Ting Lin
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Patent number: 11173188Abstract: Provided is a method of preparing an orange peel ferment, an orange peel ferment obtained therefrom, and a method for reducing fat accumulation, sleep disturbance, and cancer risk. The orange peel ferment assists obese individuals to slim down via multiple mechanisms including reducing the fat content of adipocytes, promoting lysis of triglycerides in adipocytes, and enhancing the expression of genes involved in fat metabolism, and also reduces sleep disturbance through normalizing circadian rhythm and lowers cancer risk through suppressing expression of cancer risk genes.Type: GrantFiled: August 1, 2019Date of Patent: November 16, 2021Assignee: TCI CO., LTD.Inventor: Yung-Hsiang Lin
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Patent number: 11155579Abstract: The present disclosure provides peptides comprising a motif having four amino acids, wherein each of the amino acids at N-terminus and C-terminus of the sequence independently has a same or different positively charged side chain, and each of the amino acids between the N-terminal and C-terminal of the motif independently has a same or different uncharged side chain. The present disclosure surprisingly found that these peptides have advantageous effects in inhibiting or decreasing collagen breakdown, increasing production of collagen, elastin and/or hyaluronic acid, retarding aging, improving skin and inhibiting inflammation.Type: GrantFiled: December 3, 2019Date of Patent: October 26, 2021Assignee: TCI CO., LTD.Inventors: Yung-Hsiang Lin, Yu-Ling Wang
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Patent number: 11123386Abstract: The present disclosure provides a fermentation product of Punica granatum and methods for regulating expression of MMP gene, TIMP gene and COL4A4 gene, promoting collagen production, and anti-aging by using the fermentation product of Punica granatum.Type: GrantFiled: November 30, 2018Date of Patent: September 21, 2021Assignee: TCI CO., LTD.Inventors: Yung-Hsiang Lin, Wei Hsiu Chuang
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Publication number: 20210224498Abstract: The present invention relates to a container, a package, a production system, and a distribution system. The container comprises a first identification and a second identification. The first identification is unique for identifying the container and is not exposed. The second identification is unique for identifying the container and is accessible. The second identification is different from the first identification. The second identification is associated with the first identification. The distribution system comprises a processor and a memory. The memory includes instructions causing the processor to perform operations.Type: ApplicationFiled: December 2, 2020Publication date: July 22, 2021Applicant: TCI CO., LTD.Inventors: YUNG-HSIANG LIN, Min YUE, Hsing-I WANG, Tsung Jung CHEN
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Patent number: 11066637Abstract: A live bacteria-containing particulate is provided, wherein the particulate comprises a bacterial strain, a first covering layer, and a second covering layer, and wherein the first covering layer is in-between the cell membrane and cell wall of the bacterial strain and the bacterial strain is dispersed in the second covering layer. A method of preparing a live bacteria-containing particulates is also provided, wherein the method comprises the following steps: (a) subjecting a bacterial strain to a three-stage fermentation to obtain a fermentation broth; (b) concentrating the fermentation broth to provide a concentrated bacterial solution; (c) mixing the concentrated bacterial solution with a protective agent; and (d) drying the mixture to provide live bacteria-containing particulates.Type: GrantFiled: March 23, 2020Date of Patent: July 20, 2021Assignee: TCI CO., LTD.Inventors: Yung-Hsiang Lin, Cheng-Yu Ho, Jin-Jia Wang
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Patent number: 11020445Abstract: The present invention provides a method for reducing the content of heavy metals in blood and improving the pulmonary function using green pear fruitlet extract. The green pear fruitlet extract can effectively reduce the content of harmful heavy metals in human body to prevent the harmful effects of heavy metals, and improve forced vital capacity and the peak expiratory flow of humans to reduce the respiratory resistance and increase the expiratory flow. The green pear fruitlet extract is prepared by extracting green pear fruitlet using water, alcohol, or a mixture of water and alcohol as a solvent.Type: GrantFiled: October 30, 2018Date of Patent: June 1, 2021Assignee: TCI CO., LTD.Inventors: Yung-Hsiang Lin, Yu-Ting Lin
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Patent number: 10973755Abstract: A method for protecting skin is provided. The method comprises administering to a subject in need a composition, wherein the composition comprises an effective amount of a Camellia sinensis callus extract, and the extract is a polar solvent extract of calluses of Camellia sinensis leaves. The method is especially for nursing skin, repairing skin, improving skin condition, delaying skin aging, assisting in maintaining content of collagen in skin, against photodamage, preventing skin lesions, and/or promoting wound healing.Type: GrantFiled: March 12, 2018Date of Patent: April 13, 2021Assignee: TCI CO., LTD.Inventors: Yung-Hsiang Lin, Cheng-Shing Li