Patents Assigned to Technion Research and Development Foundation
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Patent number: 12268101Abstract: Compositions comprising a) one or more amorphous superconductor layers bound to one or more flexible substrate layers, or b) one or more superconductor layers bound to one or more layers of a high dielectric material are disclosed. Furthermore, provided herein are articles comprising one or more compositions of the invention and method of manufacturing thereof.Type: GrantFiled: September 22, 2020Date of Patent: April 1, 2025Assignee: TECHNION RESEARCH &DEVELOPMENT FOUNDATION LIMITEDInventors: Yachin Ivry, Mohammad Suleiman
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Publication number: 20250101369Abstract: A method of preparing a composition comprising mycelium along with a cellulose and/or plurality of nanoparticles is described herein. The method comprises inoculating a liquid medium with fungus, the liquid medium comprising nutrients and the cellulose and/or nanoparticles. Further described herein are compositions comprising mycelium along with a cellulose and/or plurality of nanoparticles, as well as articles-of-manufacture comprising such a composition, wherein at least 10% of the cellulose and/or nanoparticles in the composition is incorporated within the mycelium. A method of enhancing fungal growth is also described, comprising contacting the fungus with a liquid medium comprising a polymer which comprises carboxylic acid groups.Type: ApplicationFiled: December 9, 2024Publication date: March 27, 2025Applicant: Technion Research & Development Foundation LimitedInventors: Noam ATTIAS, Jacob GROBMAN, Tiffany ABITBOL
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Publication number: 20250086788Abstract: A method for quantitative magnetic resonance imaging (MRI), the method includes (a) receiving a sequence of MRI images of an in vivo tissue, by an image registration deep neural network (DNN) module that was trained, by a training process, to impose one or more MRI signal related physical constraints on a content of the sequence of MRI images; and (b) extracting one or more quantitative map from the sequence of MRI images.Type: ApplicationFiled: August 14, 2024Publication date: March 13, 2025Applicants: Technion Research & Development Foundation Limited, MEDICAL RESEARCH & DEVELOPMENT FUND FOR HEALTH SERVICES, BNAI-ZION MEDICAL CENTERInventors: Mordechay Pinchas Freiman, Eyal Hanania, Israe Cohen
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Patent number: 12247231Abstract: Systems comprising a first polynucleotide comprising a regulatory element operatively linked to an open reading frame encoding an invertase enzyme and a second polynucleotide comprising a repressible regulatory element operatively linked to an open reading frame encoding a glucose oxidase enzyme wherein the repressible element inhibits transcription in response to hydrogen peroxide are provided. Cells and compositions comprising a system of the invention, as well as methods using the system of the invention, are also provided, as is artificial honey.Type: GrantFiled: October 18, 2021Date of Patent: March 11, 2025Assignee: TECHNION RESEARCH & DEVELOPMENT FOUNDATION LIMITEDInventors: Roee Amit, Shira Levi, Lidya Tannenzapf, Yehonatan Zur, Ilan Brajzblat, Assaf Licht, Ofri Warsha, Mai Dror, Dor Ben Meir, Lior Haim, Zeinat Awwad, Nir Litver, Tzila Davidov, Liron Abrahami Pachuk, Noa Eden, Hanriet Tibi, Orna Atar
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Publication number: 20250079018Abstract: A method including sensing local accelerations or changes in sensor position, including orientation and displacement, with a local acceleration sensor mounted on a chest or abdomen of a patient, and calculating energy of polyphasic motions, based on sensed information of the local acceleration sensor and classifying severity of cardiac decompensation by calculating an excessive energy index (EEi) that compares excessive energy that appears in the polyphasic motions to energy required for inspiration at a basic respiratory rate.Type: ApplicationFiled: November 14, 2024Publication date: March 6, 2025Applicants: TECHNION RESEARCH & DEVELOPMENT FOUNDATION LTD., RAMBAM HEALTH CORPORATIONInventors: Amir Landesberg, Yakov Tsibulsky, Shmuel Rispler
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Patent number: 12241776Abstract: A system and method of detecting acoustic waves including directing a continuous-wave source laser beam to an optical resonator that is impinged by acoustic the waves. Optionally, the source laser beam can propagate through the optical resonator, thereby generating a propagated laser beam. Using an interferometer, the acoustic waves can be detected by monitoring transients in an optical phase of the propagated laser beam.Type: GrantFiled: September 19, 2023Date of Patent: March 4, 2025Assignee: TECHNION RESEARCH & DEVELOPMENT FOUNDATION LIMITEDInventors: Amir Rozental, Lucas Riobo, Yoav Hazan
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Patent number: 12230306Abstract: A method, comprising: providing an electrical energy source having a specified amount of electrical energy; connecting an array comprising n magnetic tunnel junctions (MTJ) in parallel to said electrical energy source, wherein each of said MTJs is at a high resistance initial state; discharging said specified energy amount through said MTJs, thereby causing a random subset of said MTJs to switch to a lower resistance state; determining a post-discharging resistance state of each of the MTJs; and assigning a logical state to each of said MTJs corresponding to said resistance state of said MTJ.Type: GrantFiled: December 2, 2019Date of Patent: February 18, 2025Assignee: TECHNION RESEARCH &DEVELOPMENT FOUNDATION LIMITEDInventors: Shahar Kvatinsky, Ben Perach
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Publication number: 20250051348Abstract: Mechanophoric compounds featuring one or more, or two or more, clickable group(s), which are capable of being coupled to naturally occurring, synthetic and/or metallic substrates via Click chemistry, method of preparing mechanophoric matrices using the mechanophoric compounds, and mechanophoric matrices obtainable thereby, and uses thereof for detecting force-induced damage in the matrices by a colorimetric change are provided.Type: ApplicationFiled: August 13, 2024Publication date: February 13, 2025Applicant: Technion Research & Development Foundation LimitedInventors: Joshua M. GROLMAN, Yifan LIAO, Hang ZHANG, Charles Eliezer DIESENDRUCK
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Patent number: 12220246Abstract: A method comprising: generating a parametrized three-dimensional (3D) body surface model on a training set comprising a plurality of 3D scans of subjects, wherein at least some of said 3D scans are of subjects having a skeletal deformity; receiving one or more target 3D scans of a target subject; optimizing said body surface model with respect to said one or more target 3D scans to calculate a target body surface model of said target subject; training a skeletal estimation model on a training set comprising: (i) body surface models of a plurality of subjects, and (ii) skeletal landmarks sets of said plurality of subjects; and applying said trained skeletal estimation model to said calculated target body surface model of said target subject, to estimate a skeletal shape of said target subject.Type: GrantFiled: May 1, 2024Date of Patent: February 11, 2025Assignees: TECHNION RESEARCH & DEVELOPMENT FOUNDATION LIMITED, NEW YORK SOCIETY FOR THE RELIEF OF THE RUPTURED AND CRIPPLED, MAINTAINING THE HOSPITAL FOR SPECIAL SURGERYInventors: Ron Kimmel, Benjamin Groisser, Alon Wolf, Roger F. Widmann, Howard J. Hillstrom
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Publication number: 20250041275Abstract: The invention relates generally to the field of compositions including one or more conjugates of di-sugar and a nonsteroidal anti-inflammatory drug (NSAID), and use of same in methods for treating a disease or a disorder in a subject in need thereof.Type: ApplicationFiled: October 10, 2024Publication date: February 6, 2025Applicants: RAMBAM MED-TECH LTD., TECHNION RESEARCH & DEVELOPMENT FOUNDATION LIMITEDInventors: Iyad KHAMAYSI, Salim HADAD, Zaid ABASSI
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Patent number: 12217884Abstract: Protein based highly stretchable compositions with ionic conductivity are disclosed herein. Methods for preparing such compositions are also disclosed.Type: GrantFiled: October 29, 2020Date of Patent: February 4, 2025Assignee: TECHNION RESEARCH & DEVELOPMENT FOUNDATION LIMITEDInventors: Nadav Amdursky, Ramesh Nandi
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Publication number: 20250027868Abstract: An atomic interferometer system comprises optical tweezers each configured to trap at least one atom therein, an atom source system configured to release atoms, and a controller configured to control the optical tweezers to trap at least one atom released by the atom source system in one of the tweezers, to spatially split a wave function of the trapped atom between at least two of the tweezers, and to at least partially recombine the split atomic wave function in at least one of the tweezers. The atomic interferometer system can also comprise a measuring system configured to measure wavefunction population in each of the tweezers and to display an output pertaining to the wavefunction populations.Type: ApplicationFiled: July 17, 2024Publication date: January 23, 2025Applicant: Technion Research & Development Foundation LimitedInventor: Yoav SAGI
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Patent number: 12201386Abstract: Systems and methods for performing minimally invasive surgical procedures, especially for removal of tumors, and especially for brain tumors, using a robotically inserted therapeutic probe, which first detects tumorous tissue on a pre-planned path through the patient's tissue, before performing therapeutic procedures on the tissue, such as ablation. This pre-treatment detection procedure is thus able to avoid the destruction of healthy tissue. This also ensures that the therapeutic process indicated in a preoperative surgical plan is only performed on tumorous tissue, without sole reliance on preoperative image indications. This is important for neurosurgical operations performed on the brain, since preoperative images may not be accurate due to brain shift occurring during the procedure. Detection can be performed optically or ultrasonically, and treatment by laser or RF ablation. The probe insertion can be performed at 90° to the insertion axis of the device, thus minimizing passage through healthy tissue.Type: GrantFiled: September 6, 2018Date of Patent: January 21, 2025Assignee: Technion Research & Development Foundation LimitedInventors: Hadas Ziso, David Zarrouk, Moshe Shoham, Menashe Zaaroor
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Patent number: 12201628Abstract: A method for modulating an immune response by activating or inhibiting dopaminergic neurons in the Ventral Tegmental Area (VTA) is provided. Modulation is achieved by modulating the activity, the abundance or both of: a natural killer cell, a CD8 T-cell, a CD4 T-cell, a B-cell, a dendritic cell, a macrophage, a granulocyte, or their combination.Type: GrantFiled: September 19, 2022Date of Patent: January 21, 2025Assignees: TECHNION RESEARCH &DEVELOPMENT FOUNDATION LIMITED, HEALTH CORPORATION—RAMBAMInventors: Asya Rolls, Tamar Ben Shannan, Hilla Azulay-Debbie, Fahed Hakim, Maya Schiller, Shai Shen-Orr, Elina Starosvetsky
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Patent number: 12196699Abstract: The present invention relates to a chemically sensitive sensor for detecting volatile organic compounds, the sensor comprising a substrate, an electrode array, a micro-barrier, and a sensing layer comprising a multiplicity of core-shell particles in close-packed orientation, the particles comprising a metal nanoparticle (MNP) core and an organic ligand shell, wherein the MNP core has a mean particle size below about 15 nm. The invention further provides a method for fabrication of the chemically sensitive sensor.Type: GrantFiled: October 30, 2019Date of Patent: January 14, 2025Assignee: TECHNION RESEARCH & DEVELOPMENT FOUNDATION LIMITEDInventors: Hossam Haick, Yana Milyutin, Gidi Shani, Manal Abud Hawa
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Patent number: 12189762Abstract: A system, a method and a computer program product for protecting a speculative execution processor from side channel attacks, are disclosed. The system comprises a processing circuitry which performs an execution of a code segment, in one time period and copies, in another time period, only a committed portion of the executed code segment into a memory component which is accessible to read actions by an external processing unit. The speculative instructions are stored in an internal cache memory which is not accessible to read actions by the external processing unit.Type: GrantFiled: June 19, 2020Date of Patent: January 7, 2025Assignee: Technion Research & Development Foundation LimitedInventor: Abraham Mendelson
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Patent number: 12186454Abstract: A scaffold comprising electrospun decellularized ECM of an organ, wherein the decellularized ECM has a similar protein composition to native ECM of the organ. Methods of generating same are also disclosed as well as uses of same.Type: GrantFiled: January 23, 2023Date of Patent: January 7, 2025Assignee: Technion Research & Development Foundation LimitedInventors: Marcelle Machluf, Eyal Zussman, Limor Baruch
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Patent number: 12182690Abstract: A stochastic synapse for use in a neural network, comprising: first and second magnetic tunnel junction (MTJ) devices, each MTJ device having a fixed layer port and a free layer port; a first and second control circuit, each connected respectively to the free layer port of the first and second MTJ devices, wherein the fixed layer ports of the first and second MTJ devices are connected to each other; wherein the first and second control circuits are configured to perform a gated XNOR operation between synapse and activation values; and wherein an output of the gated XNOR is represented by the output current through both of the first and second MTJ devices.Type: GrantFiled: December 7, 2020Date of Patent: December 31, 2024Assignee: TECHNION RESEARCH & DEVELOPMENT FOUNDATION LIMITEDInventors: Tzofnat Greenberg, Shahar Kvatinsky, Daniel Soudry
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Publication number: 20240425938Abstract: This disclosure relates to methods and compositions useful for detecting and monitoring low-frequency mutations. Methods and compositions described herein can be used to guide clinical decisions, for example, by informing on which antibiotics should be avoided, or conversely, which antibiotics should be actively used in the case of compounds that select against a specific type of resistance.Type: ApplicationFiled: August 9, 2024Publication date: December 26, 2024Applicants: The Broad Institute, Inc., The Children's Medical Center Corporation, Technion Research & Development Foundation LimitedInventors: Gregory P. PRIEBE, Roy KISHONY, Hattie CHUNG, Matthew M. SCHAEFERS
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Patent number: 12171568Abstract: The present invention is directed to a method for inducing an immune response in a subject, including a step of activating neurons in the mesolimbic network of the subject by applying a neurofeedback.Type: GrantFiled: March 3, 2020Date of Patent: December 24, 2024Assignees: TECHNION RESEARCH & DEVELOPMENT FOUNDATION LIMITED, ICHILOV TECH LTD., RAMOT AT TEL-AVIV UNIVERSITY LTD.Inventors: Talma Hendler, Asya Rolls, Nitzan Lubianiker, Tamar Koren, Neomi Singer, Tamar Ben Shannan, Shai Shen Orr, Fahed Hakim, Hilla Azulay-Debby, Rani Cohen