Patents Assigned to Technion Research and Development Foundation
  • Patent number: 12230306
    Abstract: A method, comprising: providing an electrical energy source having a specified amount of electrical energy; connecting an array comprising n magnetic tunnel junctions (MTJ) in parallel to said electrical energy source, wherein each of said MTJs is at a high resistance initial state; discharging said specified energy amount through said MTJs, thereby causing a random subset of said MTJs to switch to a lower resistance state; determining a post-discharging resistance state of each of the MTJs; and assigning a logical state to each of said MTJs corresponding to said resistance state of said MTJ.
    Type: Grant
    Filed: December 2, 2019
    Date of Patent: February 18, 2025
    Assignee: TECHNION RESEARCH &DEVELOPMENT FOUNDATION LIMITED
    Inventors: Shahar Kvatinsky, Ben Perach
  • Publication number: 20250051348
    Abstract: Mechanophoric compounds featuring one or more, or two or more, clickable group(s), which are capable of being coupled to naturally occurring, synthetic and/or metallic substrates via Click chemistry, method of preparing mechanophoric matrices using the mechanophoric compounds, and mechanophoric matrices obtainable thereby, and uses thereof for detecting force-induced damage in the matrices by a colorimetric change are provided.
    Type: Application
    Filed: August 13, 2024
    Publication date: February 13, 2025
    Applicant: Technion Research & Development Foundation Limited
    Inventors: Joshua M. GROLMAN, Yifan LIAO, Hang ZHANG, Charles Eliezer DIESENDRUCK
  • Patent number: 12220246
    Abstract: A method comprising: generating a parametrized three-dimensional (3D) body surface model on a training set comprising a plurality of 3D scans of subjects, wherein at least some of said 3D scans are of subjects having a skeletal deformity; receiving one or more target 3D scans of a target subject; optimizing said body surface model with respect to said one or more target 3D scans to calculate a target body surface model of said target subject; training a skeletal estimation model on a training set comprising: (i) body surface models of a plurality of subjects, and (ii) skeletal landmarks sets of said plurality of subjects; and applying said trained skeletal estimation model to said calculated target body surface model of said target subject, to estimate a skeletal shape of said target subject.
    Type: Grant
    Filed: May 1, 2024
    Date of Patent: February 11, 2025
    Assignees: TECHNION RESEARCH & DEVELOPMENT FOUNDATION LIMITED, NEW YORK SOCIETY FOR THE RELIEF OF THE RUPTURED AND CRIPPLED, MAINTAINING THE HOSPITAL FOR SPECIAL SURGERY
    Inventors: Ron Kimmel, Benjamin Groisser, Alon Wolf, Roger F. Widmann, Howard J. Hillstrom
  • Publication number: 20250041275
    Abstract: The invention relates generally to the field of compositions including one or more conjugates of di-sugar and a nonsteroidal anti-inflammatory drug (NSAID), and use of same in methods for treating a disease or a disorder in a subject in need thereof.
    Type: Application
    Filed: October 10, 2024
    Publication date: February 6, 2025
    Applicants: RAMBAM MED-TECH LTD., TECHNION RESEARCH & DEVELOPMENT FOUNDATION LIMITED
    Inventors: Iyad KHAMAYSI, Salim HADAD, Zaid ABASSI
  • Patent number: 12217884
    Abstract: Protein based highly stretchable compositions with ionic conductivity are disclosed herein. Methods for preparing such compositions are also disclosed.
    Type: Grant
    Filed: October 29, 2020
    Date of Patent: February 4, 2025
    Assignee: TECHNION RESEARCH & DEVELOPMENT FOUNDATION LIMITED
    Inventors: Nadav Amdursky, Ramesh Nandi
  • Publication number: 20250027868
    Abstract: An atomic interferometer system comprises optical tweezers each configured to trap at least one atom therein, an atom source system configured to release atoms, and a controller configured to control the optical tweezers to trap at least one atom released by the atom source system in one of the tweezers, to spatially split a wave function of the trapped atom between at least two of the tweezers, and to at least partially recombine the split atomic wave function in at least one of the tweezers. The atomic interferometer system can also comprise a measuring system configured to measure wavefunction population in each of the tweezers and to display an output pertaining to the wavefunction populations.
    Type: Application
    Filed: July 17, 2024
    Publication date: January 23, 2025
    Applicant: Technion Research & Development Foundation Limited
    Inventor: Yoav SAGI
  • Patent number: 12201628
    Abstract: A method for modulating an immune response by activating or inhibiting dopaminergic neurons in the Ventral Tegmental Area (VTA) is provided. Modulation is achieved by modulating the activity, the abundance or both of: a natural killer cell, a CD8 T-cell, a CD4 T-cell, a B-cell, a dendritic cell, a macrophage, a granulocyte, or their combination.
    Type: Grant
    Filed: September 19, 2022
    Date of Patent: January 21, 2025
    Assignees: TECHNION RESEARCH &DEVELOPMENT FOUNDATION LIMITED, HEALTH CORPORATION—RAMBAM
    Inventors: Asya Rolls, Tamar Ben Shannan, Hilla Azulay-Debbie, Fahed Hakim, Maya Schiller, Shai Shen-Orr, Elina Starosvetsky
  • Patent number: 12201386
    Abstract: Systems and methods for performing minimally invasive surgical procedures, especially for removal of tumors, and especially for brain tumors, using a robotically inserted therapeutic probe, which first detects tumorous tissue on a pre-planned path through the patient's tissue, before performing therapeutic procedures on the tissue, such as ablation. This pre-treatment detection procedure is thus able to avoid the destruction of healthy tissue. This also ensures that the therapeutic process indicated in a preoperative surgical plan is only performed on tumorous tissue, without sole reliance on preoperative image indications. This is important for neurosurgical operations performed on the brain, since preoperative images may not be accurate due to brain shift occurring during the procedure. Detection can be performed optically or ultrasonically, and treatment by laser or RF ablation. The probe insertion can be performed at 90° to the insertion axis of the device, thus minimizing passage through healthy tissue.
    Type: Grant
    Filed: September 6, 2018
    Date of Patent: January 21, 2025
    Assignee: Technion Research & Development Foundation Limited
    Inventors: Hadas Ziso, David Zarrouk, Moshe Shoham, Menashe Zaaroor
  • Patent number: 12196699
    Abstract: The present invention relates to a chemically sensitive sensor for detecting volatile organic compounds, the sensor comprising a substrate, an electrode array, a micro-barrier, and a sensing layer comprising a multiplicity of core-shell particles in close-packed orientation, the particles comprising a metal nanoparticle (MNP) core and an organic ligand shell, wherein the MNP core has a mean particle size below about 15 nm. The invention further provides a method for fabrication of the chemically sensitive sensor.
    Type: Grant
    Filed: October 30, 2019
    Date of Patent: January 14, 2025
    Assignee: TECHNION RESEARCH & DEVELOPMENT FOUNDATION LIMITED
    Inventors: Hossam Haick, Yana Milyutin, Gidi Shani, Manal Abud Hawa
  • Patent number: 12186454
    Abstract: A scaffold comprising electrospun decellularized ECM of an organ, wherein the decellularized ECM has a similar protein composition to native ECM of the organ. Methods of generating same are also disclosed as well as uses of same.
    Type: Grant
    Filed: January 23, 2023
    Date of Patent: January 7, 2025
    Assignee: Technion Research & Development Foundation Limited
    Inventors: Marcelle Machluf, Eyal Zussman, Limor Baruch
  • Patent number: 12189762
    Abstract: A system, a method and a computer program product for protecting a speculative execution processor from side channel attacks, are disclosed. The system comprises a processing circuitry which performs an execution of a code segment, in one time period and copies, in another time period, only a committed portion of the executed code segment into a memory component which is accessible to read actions by an external processing unit. The speculative instructions are stored in an internal cache memory which is not accessible to read actions by the external processing unit.
    Type: Grant
    Filed: June 19, 2020
    Date of Patent: January 7, 2025
    Assignee: Technion Research & Development Foundation Limited
    Inventor: Abraham Mendelson
  • Patent number: 12182690
    Abstract: A stochastic synapse for use in a neural network, comprising: first and second magnetic tunnel junction (MTJ) devices, each MTJ device having a fixed layer port and a free layer port; a first and second control circuit, each connected respectively to the free layer port of the first and second MTJ devices, wherein the fixed layer ports of the first and second MTJ devices are connected to each other; wherein the first and second control circuits are configured to perform a gated XNOR operation between synapse and activation values; and wherein an output of the gated XNOR is represented by the output current through both of the first and second MTJ devices.
    Type: Grant
    Filed: December 7, 2020
    Date of Patent: December 31, 2024
    Assignee: TECHNION RESEARCH & DEVELOPMENT FOUNDATION LIMITED
    Inventors: Tzofnat Greenberg, Shahar Kvatinsky, Daniel Soudry
  • Publication number: 20240425938
    Abstract: This disclosure relates to methods and compositions useful for detecting and monitoring low-frequency mutations. Methods and compositions described herein can be used to guide clinical decisions, for example, by informing on which antibiotics should be avoided, or conversely, which antibiotics should be actively used in the case of compounds that select against a specific type of resistance.
    Type: Application
    Filed: August 9, 2024
    Publication date: December 26, 2024
    Applicants: The Broad Institute, Inc., The Children's Medical Center Corporation, Technion Research & Development Foundation Limited
    Inventors: Gregory P. PRIEBE, Roy KISHONY, Hattie CHUNG, Matthew M. SCHAEFERS
  • Patent number: 12171568
    Abstract: The present invention is directed to a method for inducing an immune response in a subject, including a step of activating neurons in the mesolimbic network of the subject by applying a neurofeedback.
    Type: Grant
    Filed: March 3, 2020
    Date of Patent: December 24, 2024
    Assignees: TECHNION RESEARCH & DEVELOPMENT FOUNDATION LIMITED, ICHILOV TECH LTD., RAMOT AT TEL-AVIV UNIVERSITY LTD.
    Inventors: Talma Hendler, Asya Rolls, Nitzan Lubianiker, Tamar Koren, Neomi Singer, Tamar Ben Shannan, Shai Shen Orr, Fahed Hakim, Hilla Azulay-Debby, Rani Cohen
  • Patent number: 12171545
    Abstract: A robotic shoe which provides real-time feedback regarding forces acting on the foot of the user, in order to modify these forces in a corrective or diagnostic manner. The shoe comprises an insole equipped with embedded pressure sensors enabling it to continuously monitor the ground reaction forces (GRF) and the foot center of pressure (COP) while the user is standing, walking, and running. The insole COP and GRF readings are input to a programmable system that shifts the COP trajectory dynamically in a patient-specific manner via the robotic platform of the shoe. The robotic platform contains motors that control elements whose movement manipulates the forces acting on the foot and lower limb, resulting in modification of the GRF. Closed loop feedback enables a dynamic fit of an optimal COP. The COP and GRF information can be stored for analysis and diagnosis of gait and instability events accruing during locomotion.
    Type: Grant
    Filed: June 1, 2020
    Date of Patent: December 24, 2024
    Assignee: TECHNION RESEARCH AND DEVELOPMENT FOUNDATION LTD.
    Inventors: Alon Wolf, Hadar Shaulian
  • Publication number: 20240415372
    Abstract: An assembly for driving linear movement and roll movement of an elongate surgical tool, comprising: an elongate shaft comprising a central lumen extending along the shaft long axis; the elongate shaft comprising a plurality of apertures extending across walls of the elongate shaft and into the central lumen; a set of wheels positioned opposing each other and aligned on two sides of the central lumen, the set of wheels at least partially extending through the apertures beyond the walls of the elongate shaft and into the central lumen to contact an elongate surgical tool received therein; the set of wheels being coupled to the elongate shaft and configured to rotate with the elongate shaft as a single unit when the elongate shaft is rotated about the shaft long axis.
    Type: Application
    Filed: August 23, 2024
    Publication date: December 19, 2024
    Applicants: Microbot Medical Ltd., Technion Research & Development Foundation Limited
    Inventors: Simon SHARON, Idan BOADER, Moshe SHOHAM, Eran COHEN, Eyal MORAG
  • Patent number: 12168265
    Abstract: Systems comprising a light source, thin membrane immersed in an aqueous solution and a system to direct and focus light from the light source to a spot on the membrane are provided. Methods of thinning and etching a membrane are also provided, as are membranes comprising a nanopore with a Gaussian curve shaped cross-section.
    Type: Grant
    Filed: September 23, 2021
    Date of Patent: December 17, 2024
    Assignee: TECHNION RESEARCH & DEVELOPMENT FOUNDATION LIMITED
    Inventors: Amit Meller, Tal Gilboa, Adam Zrehen, Arik Girsault, Eran Zvuloni
  • Publication number: 20240408791
    Abstract: Disclosed is a method of fabricating a construction element. The method may include assembling a mold on a rotational casting machine; rotating the mold around at least two axes at a predetermined speed; providing a first portion of magnesium silico-phosphate cement (MSPC) mix, having an altered hardening rate, to the mold while rotating the mold until at least a portion of the mold's walls is covered by a first layer of the MSPC mix; and rotating the mold until the MSPC mix is hardened to a predetermined degree.
    Type: Application
    Filed: August 20, 2024
    Publication date: December 12, 2024
    Applicant: Technion Research & Development Foundation Limited
    Inventors: Ryan POURATI, Pavel Larianovsky, Arnon Ben Tur, Jacob Grobman, Tom Shaked, Aaron Sprecher, Aharon Weissman, Bassam Masri
  • Patent number: 12165070
    Abstract: An analog signal processing circuit comprising: a first promoter operably linked to a nucleic acid sequence encoding a first output molecule, wherein said promoter is responsive to a cooperative input signal comprising at least two cooperative inputs, and wherein expression of said at least two cooperative inputs is tunable.
    Type: Grant
    Filed: June 27, 2018
    Date of Patent: December 10, 2024
    Assignee: TECHNION RESEARCH & DEVELOPMENT FOUNDATION LIMITED
    Inventors: Ramez Daniel, Loai Danial
  • Patent number: 12163120
    Abstract: A method of preparing a composition comprising mycelium along with a cellulose and/or plurality of nanoparticles is described herein. The method comprises inoculating a liquid medium with fungus, the liquid medium comprising nutrients and the cellulose and/or nanoparticles. Further described herein are compositions comprising mycelium along with a cellulose and/or plurality of nanoparticles, as well as articles-of-manufacture comprising such a composition, wherein at least 10% of the cellulose and/or nanoparticles in the composition is incorporated within the mycelium. A method of enhancing fungal growth is also described, comprising contacting the fungus with a liquid medium comprising a polymer which comprises carboxylic acid groups.
    Type: Grant
    Filed: September 10, 2021
    Date of Patent: December 10, 2024
    Assignee: Technion Research & Development Foundation Limited
    Inventors: Noam Attias, Jacob Grobman, Tiffany Abitbol