Patents Assigned to Technion Research and Development Foundation, Ltd.
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Publication number: 20140219666Abstract: A receiver and a multi-symbol-differential-detection (MSDD) module, the MSDD may include an input node for receiving an input signal having a noisy phase; a summation and rotation unit; and an output unit; wherein the output unit is arranged to output an output signal and a normalized output signal; wherein the output signal represents the input signal but has a reconstructed phase; wherein the summation and rotation unit is arranged to receive the input signal and the output signal and to provide a reference signal that reflects a weighted sum of phase rotated and delayed previously received input signals; wherein the output unit comprises a phase difference calculator, a slicer, a delay unit and a normalizer; wherein the phase difference calculator is arranged to generate a difference signal indicative of a phase difference between the reference signal and the input signal; wherein the slicer and the delay unit are arranged to generate the output signal by slicing the difference signal to provide a sliced sType: ApplicationFiled: March 1, 2012Publication date: August 7, 2014Applicant: Technion Research and Development Foundation LTD.Inventors: Igor Tselniker, Netta Sigron, Moshe Nazarathy
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Patent number: 8789795Abstract: A propulsion system and method are described configured to exert a force upon a vehicle. The system includes a concentrated mass which may be discharged from the vehicle by a propellant typically via an ejection tube. The system is optimized so that the discharged concentrated-mass imparts a large impulse upon the vehicle. The system and method may be used to alter the momentum of vehicles for propulsion, attitude correction, vehicle separation and the like.Type: GrantFiled: March 3, 2010Date of Patent: July 29, 2014Assignee: Technion Research and Development Foundation Ltd.Inventors: Alon Gany, Dan Michales
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Patent number: 8790246Abstract: A self-propelled device for locomotion through a lumen, comprising a set of serially arranged inflatable chambers, and incorporating a number of novel aspects. To enable easy insertion and use, the rigidity of the device is increased by means of rigid inserts in the balloons, or by use of stiff springs between segments. The working channel can be attached to the distal chamber of the device, such that it is pulled from the leading end of the device during inflation, rather than being pulled from the trailing end of the device during deflation. Lumen wall inspection or treatment facilities are enabled by means of a camera or treatment arm mounted between two distally positioned balloons, the device is able to provide observation capabilities to the lumen wall, yet without becoming excessively dirty by exposure to the front end of the device, as in prior art camera units.Type: GrantFiled: April 28, 2013Date of Patent: July 29, 2014Assignee: Technion Research And Development Foundation Ltd.Inventors: Noam Hassidov, Daniel Glozman, Moshe Shoham
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Patent number: 8791064Abstract: The present invention provides colloidally stable dispersions of nanoparticles comprising beta-lactoglobulin and a polysaccharide which are transparent when diluted in aqueous media. In particular these colloidally stable dispersions of nanoparticles are useful as delivery vehicles of hydrophobic nutraceuticals and fat-soluble vitamins, for enrichment of food products, especially of transparent beverages and other non-fat or low fat foods and drinks. The present invention further provides methods for the preparation of said colloidally stable dispersions.Type: GrantFiled: April 26, 2009Date of Patent: July 29, 2014Assignee: Technion Research and Development Foundation Ltd.Inventor: Yoav D. Livney
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Patent number: 8791099Abstract: Transition metal complexes of amphiphilic/bipolar corroles, optically active isomers or pharmaceutically acceptable salts thereof are useful for prevention of a cardiovascular disease or disorder in a subject susceptible to develop such a cardiovascular disease or disorder.Type: GrantFiled: August 4, 2008Date of Patent: July 29, 2014Assignee: Technion Research and Development Foundation Ltd.Inventors: Zeev Gross, Michael Aviram, Adi Haber, Bianca Fuhrman, Atif Mahammed, Raymond Coleman
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Patent number: 8784685Abstract: The invention relates to a core-alloyed shell semiconductor nanocrystal comprising: (i) a core of a semiconductor material having a selected band gap energy; (ii) a core-overcoating shell consisting of one or more layers comprised of an alloy of the said semiconductor of (i) and a second semiconductor; (iii) and an outer organic ligand layer, provided that the core semiconductor material is not HgTe. In certain embodiments, the core semiconductor material is PbSe and the alloy shell semiconductor material has the PbSexS1-x structure; or the core semiconductor material is CdTe and the alloy shell semiconductor material has either the CdTexSe1-x or CdTexS1-x structure.Type: GrantFiled: May 14, 2010Date of Patent: July 22, 2014Assignee: Technion Research and Development Foundation Ltd.Inventors: Efrat Lifshitz, Ariel Kigel, Maya Brumer-Gilary, Aldona Sashchiuk, Lilac Amirav, Viktoria Kloper, Dima Cheskis, Ruth Osovsky
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Patent number: 8779543Abstract: A semiconductor device that may include an avalanche photodiode (APD), the APD may include: a first doped region of a first polarity; a buried guard ring of a second polarity, the second polarity is opposite to the first polarity, the buried guard ring is spaced apart from the first doped region and is positioned below the first doped region; a well of the second polarity, wherein the well interfaces the first doped region to form a p-n junction; and a second doped region of the second polarity, the second doped region is spaced apart from the first doped region.Type: GrantFiled: September 16, 2012Date of Patent: July 15, 2014Assignee: Technion Research and Development Foundation Ltd.Inventors: Yael Nemirovsky, Vitali Savuskan, Sharon Bar-Lev Shefi, Igor Brouk, Gil Visokolov, Amos Fenigstein, Tomer Leitner
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Patent number: 8765467Abstract: Methods are provided for producing novel multicellular compositions comprising cancer cells together with pluripotent human stem cells, which are capable of proliferating and differentiating into various normal cell lines and tissue structures. These novel multicellular compositions are useful for investigating the properties of cancer cells in a normal human tissue microenvironment, and for studying interventions that will modulate these properties including devising, testing and screening therapeutic drugs.Type: GrantFiled: May 5, 2004Date of Patent: July 1, 2014Assignee: Technion Research and Development Foundation Ltd.Inventors: Karl L. Skorecki, Maty Tzukerman
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Patent number: 8759776Abstract: A TeraMOS sensor based on a CMOS-SOI-MEMS transistor, thermally isolated by the MEMS post-processing, designed specifically for the detection of THz radiation which may be directly integrated with the CMOS-SOI readout circuitry, in order to achieve a breakthrough in performance and cost. The TeraMOS sensor provides a low-cost, high performance THz passive or active imaging system (roughly in the range of 0.5-1.5 THz) by combining several leading technologies: Complementary Metal Oxide Semiconductor (CMOS)-Silicon on Insulator (SOI), Micro Electro Mechanical Systems (MEMS) and photonics. An array of TeraMOS sensors, integrated with readout circuitry and driving and supporting circuitry provides a monolithic focal plane array or imager. This imager is designed in a commercial CMOS-SOI Fab and the MEMS micromachining is provided as post-processing step in order to reduce cost.Type: GrantFiled: December 22, 2009Date of Patent: June 24, 2014Assignee: Technion Research and Development Foundation Ltd.Inventor: Yael Nemirovsky
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Patent number: 8759830Abstract: An electronic device (100) is presented, being configured for example as a vertical field effect transistor. The device comprises an electrically-conductive perforated patterned structure (102) which is enclosed between a dielectric layer (105) and an active element (106) of the electronic device (100). The electrically-conductive perforated patterned structure (102) comprises a geometrical pattern defining an array of spaced-apart perforation regions (108) surrounded by continuous electrically conductive regions (110). The pattern is such as to allow the active element (106) of the electronic device (100) to be in direct contact with said dielectric layer (105) aligned with the perforation regions (108). A material composition of the device (100) and features of said geometrical pattern are selected to provide a desired electrical conductance of the electrically-conductive perforated patterned structure (102) and a desired profile of a charge carriers' injection barrier along said structure (102).Type: GrantFiled: April 6, 2010Date of Patent: June 24, 2014Assignee: Technion Research and Development Foundation Ltd.Inventors: Nir Tessler, Ariel Ben-Sasson
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Patent number: 8741581Abstract: The present invention relates to methods for detecting, prognosing and staging cancers, in particular cancers of the gastrointestinal tract. The methods of the invention comprise detecting specific protein markers in a tissue of interest, wherein the detected levels thereof may be indicative of pre-cancerous or cancerous tissue, or the stage or prognosis of a cancer. Further provided are methods of treating cancer, and cancer detection kits.Type: GrantFiled: April 27, 2010Date of Patent: June 3, 2014Assignee: Technion Research and Development Foundation Ltd.Inventors: Arie Admon, Eilon Barnea, Ilan Beer, Tamar Ziv
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Patent number: 8709480Abstract: A method of in-situ adhering including providing pre-gel including phenolic compound and water miscible polymers like carbohydrates, salts of anionic polysaccharide, spreading layer of pre-gel onto a surface, adding solid support, comprising cross linking agents capable of interacting with the polymer, to pre-gel, and allowing pre-gel to cure and adhere onto surface.Type: GrantFiled: November 5, 2008Date of Patent: April 29, 2014Assignee: Technion Research and Development Foundation Ltd.Inventors: Havazelet Bianco-Peled, Ohad Kimhi
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Patent number: 8685955Abstract: Novel iron chelators exhibiting neuroprotective and good transport properties are useful in iron chelation therapy for treatment of a disease, disorder or condition associated with iron overload and oxidative stress, e.g., a neurodegenerative or cerebrovascular disease or disorder, a neoplastic disease, hemochromatosis, thalassemia, a cardiovascular disease, diabetes, an inflammatory disorder, anthracycline cardiotoxicity, a viral infection, a protozoal infection, a yeast infection, retarding aging, and prevention and/or treatment of skin aging and skin protection against sunlight and/or UV light. The iron chelator function is provided by a 8-hydroxyquinoline, a hydroxypyridinone or a hydroxamate moiety. The neuroprotective function is imparted to the compound, e.g., by a neuroprotective peptide. A combined antiapoptotic and neuroprotective function is provided by a propargyl group.Type: GrantFiled: November 14, 2011Date of Patent: April 1, 2014Assignees: Technion Research and Development Foundation Ltd., Yeda Research and Development Co. Ltd.Inventors: Moussa B. H. Youdim, Matitiyahu Fridkin, Hailin Zheng, Rivka Warshawsky
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Patent number: 8673354Abstract: A composition including pre-gel including at least one phenol-based compound, excluding phloroglucinol and derivatives, at least one water miscible polymer, at least one cross linking agent capable of interacting with the polymer. The polymer is selected from one or more natural and/or synthetic carbohydrate, and salt of an anionic polysaccharide.Type: GrantFiled: November 5, 2008Date of Patent: March 18, 2014Assignee: Technion Research and Development Foundation Ltd.Inventors: Havazelet Bianco-Peled, Ohad Kimhi
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Patent number: 8672145Abstract: A sorbent polymer is provided that interacts or reacts with aqueous urea to aid the regeneration of a dialysate liquid. The sorbent polymer may include one or more specific functional groups bonded thereto. Such specific functional groups are selected from carboxylic acids, carboxylic acid esters, carboxylates, amides, dicarboxylic acids, dicarboxylic acid esters, and dicer boxylates to produce the desired urea sorbent.Type: GrantFiled: July 29, 2013Date of Patent: March 18, 2014Assignees: Fresenius Medical Care Holdings, Inc., The Technion Research and Development Foundation, Ltd.Inventor: Moris S. Eisen
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Publication number: 20140065402Abstract: The present invention relates to hybrid electrically conducting systems comprising a matrix of a conducting polymer (polyaniline-PANI), and highly conducting carbonaceous nanoparticles, e.g., carbon nanotubes (CNT) or graphenes. The PANI/carbon nano-composites are prepared by a novel process comprising the steps of (a) polymerizing aniline and carbonaceous nanoparticles by inverse emulsion polymerization conducted under sonication, so as to obtain PANI/carbon nano-composites; (b) de-doping the PANI/carbon nano-composites obtained in step (a); (c) re-doping the PANI/carbon nano-composites obtained in step (b); and (d) forming a film from the re-doped PANI/carbon nano-composites. The PANI/carbon nano-composites are used for the preparation of thin, transparent, and conductive films which can be applied to a variety of substrates and used for commercial applications.Type: ApplicationFiled: September 3, 2013Publication date: March 6, 2014Applicant: Technion Research and Development Foundation Ltd.Inventors: Ran Yosef SUCKEVERIENE, Moshe NARKIS
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Patent number: 8609719Abstract: A method for treating an individual who has been identified as having Alzheimer's disease by administering orally to the individual a therapeutically effective amount of ladostigil or a pharmaceutically active salt thereof, wherein the therapeutically effective amount is 70 mg per day, 140 mg per day, or 200 mg per day. Also, a unit dosage form of ladostigil or a pharmaceutically active salt thereof in an amount of 50 mg, 70 mg, 80 mg or 100 mg.Type: GrantFiled: October 20, 2009Date of Patent: December 17, 2013Assignees: Yissum Research Development Company of the Hebrew University of Jerusalem, Technion Research and Development Foundation Ltd.Inventors: Victor Piryatinsky, Bronka Cohen, David Lerner, Dalia Pinkert, Istvan Miskolczi, Yaacov Herzig, Hugo Gottlieb, Marta Weinstock-Rosin
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Patent number: 8597953Abstract: A set of volatile organic compounds is provided, comprising at least butylated hydroxy toluene or 4,6-di (1,1-dimethylethyl)-2-methyl-phenol for breath analysis. Methods of use thereof in diagnosing, monitoring or prognosing lung cancer are also disclosed.Type: GrantFiled: January 10, 2010Date of Patent: December 3, 2013Assignee: Technion Research and Development Foundation Ltd.Inventor: Hossam Haick
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Publication number: 20130313188Abstract: A sorbent polymer is provided that interacts or reacts with aqueous urea to aid the regeneration of a dialysate liquid. The sorbent polymer may include one or more specific functional groups bonded thereto. Such specific functional groups are selected from carboxylic acids, carboxylic acid esters, carboxylates, amides, dicarboxylic acids, dicarboxylic acid esters, and dicer boxylates to produce the desired urea sorbent.Type: ApplicationFiled: July 29, 2013Publication date: November 28, 2013Applicants: The Technion Research and Development Foundation, LTD., Fresenius Medical Care Holdings, Inc.Inventor: Moris S. Eisen
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Publication number: 20130296331Abstract: The invention provides compositions and methods for ameliorating renal dysfunction induced by renal hypoperfusion or acute kidney injury, resulting for example from increased intra-abdominal pressure, using phosphodiesterase inhibitors, more particularly phosphodiesterase type inhibitors, or pharmaceutically acceptable salts or solvates thereof.Type: ApplicationFiled: November 24, 2011Publication date: November 7, 2013Applicant: Technion Research and Development Foundation Ltd.Inventors: Zaid Abassi, Bishar Bishara