Abstract: An apparatus for the introduction of a drainage tube into a patient's chest cavity, comprising a housing having a distal end, a proximal end, and a longitudinal axis; a scalpel operable in a protruding position between a closed position in which the cutting portions are adjacent one another and adapted to make an incision in the dermis of the patient, and an open position in which the cutting portions are spaced from one another forming a scalpel passage along the longitudinal axis between the cutting portions. The apparatus further comprising a trocar comprising first and second trocar portions, each extending along the length of the trocar; the trocar being operable between an closed position wherein the first and second trocar portions are substantially adjacent one another, and a closed position in which the first and second trocar portions are spaced from one another and adapted for the introduction of the drainage tube therethrough.

Abstract: The present invention relates to methods for detecting, prognosing and staging cancers, in particular cancers of the gastrointestinal tract. The methods of the invention comprise detecting specific protein markers in a tissue of interest, wherein the detected levels thereof may be indicative of pre-cancerous or cancerous tissue, or the stage or prognosis of a cancer. Further provided are methods of treating cancer, and cancer detection kits.

Abstract: Propargylamine, propargylamine derivatives including N-propargyl-1-aminoindan, enantiomers and analogs thereof, and pharmaceutically acceptable salts thereof, are useful for prevention or treatment of cardiovascular disorders, diseases and conditions.

Abstract: A CMOS integrated circuit for multi-channel neuronal recording with twelve true-differential channels, band separation and digital offset calibration. The recorded signal is separated into 2 bands: a low-frequency, local field potential (LFP); and high-frequency spike data. Digitally programmable gains for the LFP and spike bands are provided. A mixed-signal front-end processor for multi-channel neuronal recording is also described. It receives twelve differential-input channels of implanted recording electrodes. A programmable cutoff HPF blocks DC and low frequency input drift at about 1 Hz. The signals are band-split at about 200 Hz to low-frequency local field potential (LFP) and high-frequency spike data (SPK), which is band limited by a programmable-cutoff LPF. The analog signals are converted into digital form, and streamed out over a serial digital bus at up to 8 Mbps.

Abstract: Novel iron chelators exhibiting neuroprotective and good transport properties are useful in iron chelation therapy for treatment of a disease, disorder or condition associated with iron overload and oxidative stress, eg. a neurodegenerative or cerebrovascular disease or disorder, a neoplastic disease, hemochromatosis, thalassemia, a cardiovascular disease, diabetes, a inflammatory disorder, anthracycline cardiotoxicity, a viral infection, a protozoal infection, a yeast infection, retarding ageing, and prevention and/or treatment of skin ageing and skin protection against sunlight and/or UV light. The iron chelator function is provided by a 8-hydroxyquinoline, a hydroxypyridinone or a hydroxamate moiety, the neuroprotective function is imparted to the compound e.g. by a neuroprotective peptide, and a combined antiapoptotic and neuroprotective function by a propargyl group.

Abstract: A wave-guiding system and method for mode-selective transmission of a spatially coherent light beam is disclosed. The system comprises a wave-guide with an inlet and an outlet for transmitting one or more modes; a first mode-shaping optical element for shaping the spatially coherent light beam before it enters through the inlet of the wave-guide to a desired mode of the wave-guide; and a second mode-shaping optical element for shaping light beam after it exits from the outlet of the wave-guide for obtaining a desired vectorial field.

Abstract: A method is provided for producing semiconductor nanoparticles comprising: (i) dissolving a semiconductor compound or mixture of semiconductor compounds in a solution; (ii) generating spray droplets of the resulting solution of semiconductor compound(s); (iii) vaporizing the solvent of said spray droplets, consequently producing a stream of unsupported semiconductor nanoparticles; and (iv) collecting said unsupported semiconductor nanoparticles on a support.

Abstract: System and method for visually tracking a target object silhouette in a plurality of video frames under very general conditions. The tracker does not make any assumption about the object or the scene. The tracker works by approximating, in each frame, a PDF (probability distribution function) of the target's bitmap and then estimating the maximum a posteriori bitmap. The PDF is marginalized over all possible motions per pixel, thus avoiding the stage in which optical flow is determined. This is an advantage over other general-context trackers that do not use the motion cue at all or rely on the error-prone calculation of optical flow. Using a Gibbs distribution with a first order neighborhood system yields a bitmap PDF whose maximization may be transformed into that of a quadratic pseudo-Boolean function, the maximum of which is approximated via a reduction to a maximum-flow problem.

Abstract: A system and method for detecting a sound originating from a body and enhancing signal-to-noise ratio with respect to noise originated outside the body is disclosed. The system comprises a light source for producing a quasi-monochromatic, spatially-coherent light beam; and interferometer for interfering alight beam originated from the source, incident upon the body and reflected from it, with a reference beam, which also originates from the light source; and a detector for detecting changes caused by motion of a least one interference fringe across the detector, and for generation a corresponding electric signal.

Abstract: Disclosed are formulations of ladostigil tartrate, including pharmaceutical compositions, process for the manufacture, and use thereof.

Abstract: An antimicrobial packaging material for food stuffs containing from 0.05% to 1.5% by weight of a natural essential oil. The oil can be selected from primarily linalool and/or methylchavicol, but also from one or more of citral, geraniol, methyl cinnamate, methyl eugenol, 1,8-cineole, trans-a-bergamotene, carvacrol and thymol blended with one or more polymers selected from ethylene vinyl alcohol copolymer, polyacrylates, including ethyl acrylate methyl methacrylate copolymers, lonomers, nylons and other hydrophilic polymers or polymers possessing functional groups capable of partially anchoring the additives and the blender mix is coated onto the food contact face of a food grade packaging film or incorporated into a food grade packaging film. A binding agent such as polyethylene glycol is added to the blend to improve the retention of the volatile oil in the polymer during processing. This material has no regulatory limitations and, at the referred concentrations, does not form detectable off-flavors.

Abstract: Propargylamine, propargylamine derivatives including N-propargyl-1-aminoindan, enantiomers and analogs thereof, and pharmaceutically acceptable salts thereof, are useful for prevention or treatment of cardiovascular disorders, diseases and conditions.

Abstract: The present invention relates to a method, and system for implementing the method, for performing incremental validation of an XML document with respect to XML Schema key and keyref constraints, and handling the semantics dictated by the XML Schema specification. Several operations are defined that change the content of a document, i.e., add or remove nodes, or change the value of existing nodes. The present invention verifies whether performing such an operation would violate key or keyref constraints, and allows changing the document only if the operation maintains the validity of the document with respect to the constraints. The verification traverses only the parts of the document that may be affected by the change operation, and not the whole document. The invention maintains, in an efficient manner, data structures that hold information relevant to the validation of key and keyref constraints.

Abstract: An apparatus for all-optical deflection of an incident optical signal beam, the apparatus comprising: a photorefractive semiconductor crystal; and an electric field source, for applying an electric field across the crystal either through electrodes or by positioning the crystal at a place where an electric field is present. In another embodiment of the invention a second optical beam source, for illuminating the crystal with a background optical beam. The apparatus is used for steering the signal beam, lensing it or for other applications.

Abstract: Aqueous fluid polluted with phosphate contaminants is mixed with or passed through an adsorbent material selected from: (i) particles of oxides or hydroxides of transition metals, aluminum oxides or hydroxides, TiO2, or mixtures thereof, or (ii) particles of activated carbon, activated alumina, aluminum oxide, activated TiO2, TiO2, mineral clay, zeolite, or an ion exchanger loaded with nanoparticles of oxides or hydroxides of transition metals, aluminum oxides or hydroxides or TiO2, or mixtures thereof, to yield aqueous fluid purified from phosphate. The adsorbent material is further regenerated by increasing the pH of the adsorbent sludge, concentrated phosphate solution or a phosphate crystal slurry is recovered as well.

Abstract: A method for enhancing underwater imaging affected by image degradation effects, the method comprising: acquiring at least one image of an underwater scene using an imaging device; determining information regarding distances of parts of the scene relative to the imaging device; and reconstructing an image of the underwater scene using a physics-based mathematical model, compensating image characteristics influenced by distance-dependent underwater degradation effects including veiling light, using the information on the distances of parts of the scene from the imaging device, and compensating distance-dependent underwater degradation effects relating to the distance of illumination sources from the scene.

Abstract: An apparatus for providing a light beam with spatially varying polarization. The apparatus includes: two circumferentially curved reflectors positioned substantially opposite each other, a polarizer positioned in an optical path between the two reflectors, for polarizing light reflected from one reflector before it reaches the other. A non-polarized light beam incident along a given axis on one of the reflectors is radially reflected off that reflector, acquires predetermined polarization from the polarizer and is then reflected off the second reflector to a light beam of spatially varying polarization.

Abstract: A device for improved vision into or out of at least one eye of a subject. The device comprises an enclosing vessel for holding one or more lenses in front one or two eyes of the subject and for holding a substance whose refractive index is matched to the refractive index of the cornea. The vessel is adapted to seal the substance to the face around the eye or eyes of the subject thereby allowing focusing into or out of the eye or eyes.

Abstract: An apparatus for the introduction of a drainage tube into a patient's chest cavity, comprising a housing having a distal end, a proximal end, and a longitudinal axis; a scalpel operable in a protruding position between a closed position in which the cutting portions are adjacent one another and adapted to make an incision in the dermis of the patient, and an open position in which the cutting portions are spaced from one another forming a scalpel passage along the longitudinal axis between the cutting portions. The apparatus further comprising a trocar comprising first and second trocar portions, each extending along the length of the trocar; the trocar being operable between an closed position wherein the first and second trocar portions are substantially adjacent one another, and a closed position in which the first and second trocar portions are spaced from one another and adapted for the introduction of the drainage tube therethrough.

Abstract: A method of and device for sampling polycyclic aromatic hydrocarbons (PAHs) in the ambient environment, the method including: (a) providing a polymer film for collecting the PAHs; (b) exposing the polymer film to a gas containing the PAHs, and (c) performing an analysis of the PAHs collected by the polymer film, the analysis being selected from the group consisting of fluorescence analysis and Fourier Transform Imaging Microscopy (FT-SIM).