Abstract: A radiation conversion device is presented comprising at least one radiation conversion cell. The radiation conversion cell comprises a photo-absorber unit having a predetermined absorption spectrum for absorbing radiation of a certain wavelength range thereby converting the absorbed radiation into charge carriers, and at least partially reflective layer structure configured to be substantially reflective for said certain wavelength range.
Type:
Application
Filed:
May 10, 2012
Publication date:
April 3, 2014
Applicant:
TECHNION RESEARCH AND DEVELOPMENT FOUNDATION LTD.
Inventors:
Avner Rotschild, Hen Dotan, Ofer Kfir, Elad Sharlin
Abstract: Novel iron chelators exhibiting neuroprotective and good transport properties are useful in iron chelation therapy for treatment of a disease, disorder or condition associated with iron overload and oxidative stress, e.g., a neurodegenerative or cerebrovascular disease or disorder, a neoplastic disease, hemochromatosis, thalassemia, a cardiovascular disease, diabetes, an inflammatory disorder, anthracycline cardiotoxicity, a viral infection, a protozoal infection, a yeast infection, retarding aging, and prevention and/or treatment of skin aging and skin protection against sunlight and/or UV light. The iron chelator function is provided by a 8-hydroxyquinoline, a hydroxypyridinone or a hydroxamate moiety. The neuroprotective function is imparted to the compound, e.g., by a neuroprotective peptide. A combined antiapoptotic and neuroprotective function is provided by a propargyl group.
Type:
Grant
Filed:
November 14, 2011
Date of Patent:
April 1, 2014
Assignees:
Technion Research and Development Foundation Ltd., Yeda Research and Development Co. Ltd.
Inventors:
Moussa B. H. Youdim, Matitiyahu Fridkin, Hailin Zheng, Rivka Warshawsky
Abstract: A composition including pre-gel including at least one phenol-based compound, excluding phloroglucinol and derivatives, at least one water miscible polymer, at least one cross linking agent capable of interacting with the polymer. The polymer is selected from one or more natural and/or synthetic carbohydrate, and salt of an anionic polysaccharide.
Type:
Grant
Filed:
November 5, 2008
Date of Patent:
March 18, 2014
Assignee:
Technion Research and Development Foundation Ltd.
Abstract: A sorbent polymer is provided that interacts or reacts with aqueous urea to aid the regeneration of a dialysate liquid. The sorbent polymer may include one or more specific functional groups bonded thereto. Such specific functional groups are selected from carboxylic acids, carboxylic acid esters, carboxylates, amides, dicarboxylic acids, dicarboxylic acid esters, and dicer boxylates to produce the desired urea sorbent.
Type:
Grant
Filed:
July 29, 2013
Date of Patent:
March 18, 2014
Assignees:
Fresenius Medical Care Holdings, Inc., The Technion Research and Development Foundation, Ltd.
Abstract: An electronic device is presented, such as a thin film transistor. The device comprises a patterned electrically-conductive layer associated with an active element of the electronic device. The electrically-conductive layer has a pattern defining an array of spaced-apart electrically conductive regions. This technique allows for increasing an electric current through the device.
Type:
Application
Filed:
September 16, 2013
Publication date:
March 6, 2014
Applicant:
TECHNION RESEARCH AND DEVELOPMENT FOUNDATION LTD.
Inventors:
Nir TESSLER, Moti MARGALIT, Oded GLOBERMAN, Roy SHENHAR
Abstract: The present invention relates to hybrid electrically conducting systems comprising a matrix of a conducting polymer (polyaniline-PANI), and highly conducting carbonaceous nanoparticles, e.g., carbon nanotubes (CNT) or graphenes. The PANI/carbon nano-composites are prepared by a novel process comprising the steps of (a) polymerizing aniline and carbonaceous nanoparticles by inverse emulsion polymerization conducted under sonication, so as to obtain PANI/carbon nano-composites; (b) de-doping the PANI/carbon nano-composites obtained in step (a); (c) re-doping the PANI/carbon nano-composites obtained in step (b); and (d) forming a film from the re-doped PANI/carbon nano-composites. The PANI/carbon nano-composites are used for the preparation of thin, transparent, and conductive films which can be applied to a variety of substrates and used for commercial applications.
Type:
Application
Filed:
September 3, 2013
Publication date:
March 6, 2014
Applicant:
Technion Research and Development Foundation Ltd.
Abstract: A three-dimensional fibrin engineered tissue construct is provided selected from: (i) a fibrin gel matrix comprising a combination of tissue-specific cells and at least one type of vascular cells; and (ii) a hybrid scaffold of fibrin gel and a polymeric synthetic scaffold comprising at least one type of vascular cells or a combination of tissue-specific cells and at least one type of vascular cells.
Type:
Application
Filed:
February 13, 2012
Publication date:
February 20, 2014
Applicant:
TECHNION RESEARCH AND DEVELOPMENT FOUNDATION LTD.
Abstract: Transition metal complexes of amphiphilic corroles, optical isomers and pharmaceutically acceptable salts thereof are useful for neuroprotection and neurorescue, particularly for treatment of diabetes and neurodegenerative diseases. The amphiphilic corrole is preferably a 5,10,15-tris-aryl- or 5,10,15-tris-CF3-corrole, and said transition metal complex more preferably has the formula I defined in the specification. Also provided are propargyl-containing corroles carrying one or more radicals substituted by a propargylamino group or one or more nitrogen-containing heteroaryl radicals substituted by propargyl at the ring N atom.
Type:
Application
Filed:
September 3, 2013
Publication date:
February 13, 2014
Applicant:
TECHNION RESEARCH AND DEVELOPMENT FOUNDATION LTD.
Inventors:
Moussa B.H. YOUDIM, Silvia MANDEL, Tamar AMIT, Orit BAR-AM, Lana KUPERSHMIDT, Zeev GROSS, Atif MAHAMMED, Irena SALTSMAN, Zoya OKUN
Abstract: A method for treating an individual who has been identified as having Alzheimer's disease by administering orally to the individual a therapeutically effective amount of ladostigil or a pharmaceutically active salt thereof, wherein the therapeutically effective amount is 70 mg per day, 140 mg per day, or 200 mg per day. Also, a unit dosage form of ladostigil or a pharmaceutically active salt thereof in an amount of 50 mg, 70 mg, 80 mg or 100 mg.
Type:
Grant
Filed:
October 20, 2009
Date of Patent:
December 17, 2013
Assignees:
Yissum Research Development Company of the Hebrew University of Jerusalem, Technion Research and Development Foundation Ltd.
Inventors:
Victor Piryatinsky, Bronka Cohen, David Lerner, Dalia Pinkert, Istvan Miskolczi, Yaacov Herzig, Hugo Gottlieb, Marta Weinstock-Rosin
Abstract: A method for determining an optimal location for positioning an image capturing device within a volume, the method including, obtaining a plurality of points to be visible from the image capturing device, performing inversion on points located in the vicinity of the plurality of points thus creating a computerized inversed object, each point in the vicinity of the plurality of point is translated to a corresponding point in the computerized inversed object, defining a convex hull of the inversed object, determining if a point of the plurality of points is visible from the viewpoint according to the position of its corresponding point on the convex hull relative to its neighbor points, repeating said determining for multiple locations within the volume, determining whether a predetermined set of points is visible from each location, selecting the optimal location of the image capturing device based on the results of said repeated determining.
Type:
Application
Filed:
August 7, 2013
Publication date:
December 5, 2013
Applicant:
TECHNION RESEARCH AND DEVELOPMENT FOUNDATION LTD.
Abstract: A set of volatile organic compounds is provided, comprising at least butylated hydroxy toluene or 4,6-di (1,1-dimethylethyl)-2-methyl-phenol for breath analysis. Methods of use thereof in diagnosing, monitoring or prognosing lung cancer are also disclosed.
Type:
Grant
Filed:
January 10, 2010
Date of Patent:
December 3, 2013
Assignee:
Technion Research and Development Foundation Ltd.
Abstract: A sorbent polymer is provided that interacts or reacts with aqueous urea to aid the regeneration of a dialysate liquid. The sorbent polymer may include one or more specific functional groups bonded thereto. Such specific functional groups are selected from carboxylic acids, carboxylic acid esters, carboxylates, amides, dicarboxylic acids, dicarboxylic acid esters, and dicer boxylates to produce the desired urea sorbent.
Type:
Application
Filed:
July 29, 2013
Publication date:
November 28, 2013
Applicants:
The Technion Research and Development Foundation, LTD., Fresenius Medical Care Holdings, Inc.
Abstract: The invention provides compositions and methods for ameliorating renal dysfunction induced by renal hypoperfusion or acute kidney injury, resulting for example from increased intra-abdominal pressure, using phosphodiesterase inhibitors, more particularly phosphodiesterase type inhibitors, or pharmaceutically acceptable salts or solvates thereof.
Type:
Application
Filed:
November 24, 2011
Publication date:
November 7, 2013
Applicant:
Technion Research and Development Foundation Ltd.
Abstract: A non transitory computer readable medium and a method of detecting excavation of an underground tunnel, the method includes: propagating a light pulse through an underground optic fiber; generating detection signals responsive to Brillion scattered light resulting from the propagating of the light pulse through the underground optic fiber; wherein the detection signals represent tension values at multiple locations along the underground optic fiber; and processing the detection signals to detect excavation of the underground tunnel.
Type:
Grant
Filed:
November 24, 2010
Date of Patent:
November 5, 2013
Assignee:
Technion Research and Development Foundation Ltd.
Abstract: A method and apparatus for resolving conjunctive queries, comprising relational predicates and external predicates, such as XML predicates. The method and apparatus obtain results from a relational engine or from an external engine, and then use the obtained results as input for the other engine, so as to optimize the activity of the other engine. The process may repeat further times, with the results obtained by the other engine being input to the first engine. The method and apparatus further disclose handling value, being isomorphic hierarchical sub-trees.
Type:
Application
Filed:
June 18, 2013
Publication date:
October 24, 2013
Applicant:
TECHNION RESEARCH AND DEVELOPMENT FOUNDATION LTD.
Abstract: The present invention introduces a new technique allowing the fabrication of high-aspect ratio nanoscale semiconductor structures and local device modifications using FIB technology. The unwanted semiconductor sputtering in the beam tail region prevented by a thin slow-sputter-rate layer which responds much slower and mostly to the high-intensity ion beam center, thus acting as a saturated absorber funnel-like mask for the semiconductor. The protective layer can be deposited locally using FIB, thus enabling this technique for local device modifications, which is impossible using existing technology. Furthermore, such protective layers allow much higher resolution and nanoscale milling can be achieved with very high aspect ratios, e.g. Ti layer results in aspect ratio higher than 10 versus bare semiconductor milling ratio of about 3.
Type:
Grant
Filed:
April 27, 2008
Date of Patent:
October 15, 2013
Assignee:
Technion Research and Development Foundation Ltd.
Abstract: An electronic device is presented, such as a thin film transistor. The device comprises a patterned electrically-conductive layer associated with an active element of the electronic device. The electrically-conductive layer has a pattern defining an array of spaced-apart electrically conductive regions. This technique allows for increasing an electric current through the device.
Type:
Grant
Filed:
November 2, 2012
Date of Patent:
October 8, 2013
Assignee:
Technion Research and Development Foundation Ltd.
Inventors:
Nir Tessler, Moti Margalit, Oded Globerman, Roy Shenhar
Abstract: An add-on sling-load system (100, 200, 300, 400, 600) capable of being attached to a host that comprises a load (120, 230) provided with at least two slices arranged in a predetermined configuration and preferably a stack and a controlled coupling mechanism (130, 620) configured to attach and release at least one slice from the arranged configuration. The sling load system is used for multiple deliveries.
Type:
Application
Filed:
December 7, 2011
Publication date:
October 3, 2013
Applicant:
TECHNION RESEARCH AND DEVELOPMENT FOUNDATION LTD.
Abstract: The present invention relates to novel quinoxaline, quinazoline and phthalazine derivatives as well as multimeric derivatives, methods for their preparation, pharmaceutical compositions including such compounds, and methods of using these compounds for the treatment and prevention of brain damage resulting from brain injury, especially secondary brain damage due to traumatic brain injury (TBI). The compounds of the invention are also useful in treating and preventing neurodegenerative diseases.
Type:
Grant
Filed:
August 22, 2006
Date of Patent:
September 24, 2013
Assignee:
Technion Research and Development Foundation Ltd.
Inventors:
Moshe Gavish, Jehuda Arieh Veenman, Alex Shterenberg, Ilan Marek
Abstract: The present invention provides a sensor or a system comprising gold nanoparticles coated with specific organic coatings for diagnosing, staging or monitoring chronic kidney disease.
Type:
Application
Filed:
March 11, 2013
Publication date:
September 12, 2013
Applicant:
Technion Research and Development Foundation Ltd.