Abstract: The present invention refers to novel conjugate molecules and their use or the transport of nano- and macromolecular structures into cells and/or the nucleus. More particularly, the present invention refers to conjugate molecules containing a carrier, preferably thiopyridyl moieties, and a cargo moiety. Thereby, the thiopyridyl moiety is bound to the cargo moiety to act as a carrier, particularly for efficient intracellular and/or intranuclear delivery of drugs, nano-or macromolecular structures, etc. The novel conjugate molecules are provided for the manufacture of a medicament for gene therapy, apoptosis, or for the treatment of diseases such as cancer, autoimmune diseases or infectious diseases.

Abstract: The invention comprises a system and method for employing video in development processes. A new theory of operation for mapping video to formal models is disclosed. The present invention combines a runtime component and an object memory with an transformer component and offers several inputs and outputs. At least one capture device allows input of video. Video is structurally decomposed into shots and annotated following a semiology-based video model and stored in object memory. A runtime component determines the shots that are played back on one or more displays. A spectator may influence the runtime component by changing its state via at least one controller. One or more downstream development processes can access the object memory to extract customary models for requirements specification. The present invention can play a useful role for development teams that are distributed over large areas by providing common reference points in shots representing the application domain.

Abstract: A device for spectroscopy using charged analytes has an electron generator, which sends electrons through membrane into a charging chamber. The thermal strain of the membrane may be lowered significantly if a material is selected for the membrane which contains at least one component from the group of oxides, nitrides, and carbides with at least one of the elements B, Al, C, Si, and Ti or polysilicon.

Abstract: In a device for conveying and positioning structural elements at a conveying track, a structural element is brought into pending state at the conveying track and the conveying track is tilted in conveying direction so that the structural element slides downwards to approach a target point. The position of the structural element is detected. The device further includes a control unit wherein the position of the structural element is detected within a predetermined range of the target point to be reached, and a time, at which the conveying track is tilted and re-tilted at a predetermined angular speed by a predetermined angle, is determined by using a calculation and control algorithm, so that the structural element is intercepted.