Patents Assigned to Technische Universitaet Dresden
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Publication number: 20170127953Abstract: A device for adjusting and determining the blood flow plateau at a patient's limb, wherein the device includes an chamber the wall of which surrounds an inner space, and at least one opening for inserting at least a part of the limb into the inner space as well as at least one recess, that allows access to the part of the limb that is located inside the inner space, are formed in the chamber, and wherein the device includes at least one heating element that is in thermal contact with the inner space. In this context, it is provided that the device further includes an apparatus for determining the blood flow plateau at the part of the limb that is located inside the inner space.Type: ApplicationFiled: January 30, 2015Publication date: May 11, 2017Applicant: TECHNISCHE UNIVERSITÄT DRESDENInventors: Graeme EISENHOFER, Christina PAMPORAKI, Angelos FILIPPATOS
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Patent number: 9595692Abstract: The invention relates to a method for producing an organic component in which a layer stack comprising an electrode, a counter-electrode and one or more organic layers is produced and in which a functional layer with metal particle nanoclusters is formed in the layer stack, wherein here in the layer stack a base layer of an inorganic material is produced on an underlying stack region which comprises at least one organic layer and an arrangement of isolated metal particle nanoclusters is formed on the base layer. The invention further relates to an organic component.Type: GrantFiled: December 20, 2013Date of Patent: March 14, 2017Assignee: Technische Universität DresdenInventors: Till Jaegeler-Hoheisel, Tobias Schwab, Sylvio Schubert, Moritz Riede, Karl Leo
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Patent number: 9566575Abstract: The invention relates to a method for producing activated carbon provided and/or impregnated with a metal-organic framework substance (MOF material), the activated carbon being in particular in the form of discrete activated carbon particles, and preferably for producing an activated carbon with a reactive and/or catalytic action. The metal-organic framework substance is produced in situ in the pores and/or in the pore system of the activated carbon, starting from at least one metal precursor compound (MP) containing a metal and at least one ligand precursor (LP).Type: GrantFiled: March 11, 2014Date of Patent: February 14, 2017Assignees: Blücher GmbH, Technische Universität DresdenInventors: Bertram Bohringer, Ilsebill Eckle, Stefan Kaskel, Martin R. Lohe
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Patent number: 9562306Abstract: A fabric structure (1) having a cellular construction. The fabric structure comprises at least one base layer (6) consisting of warp threads (10), at least one top layer (7) consisting of warp threads (11) and weft threads (2) placed in between, wherein the fabric structure (1) is formed by a multiplicity of three-dimensional cells (3, 9) and the height (8) of each individual cell (3, 9) is defined by the spacing (8) between two warp threads (10, 11), located above the other in height direction z, in adjacent layers (6, 7), the length (12) of the cell (3, 9) is defined by the spacing (12) between two warp threads (10) or (11) adjacent in the weft direction x, in one layer (6, 7) and the width (13, 14) of a cell (3, 9) is defined by the extent (13) of the weft thread course in the warp direction y and/or the spacing (14) between the two weft threads (2) that are opposite in the warp direction y and adjacent to the particular cell (9).Type: GrantFiled: February 6, 2014Date of Patent: February 7, 2017Assignee: TECHNISCHE UNIVERSITÄT DRESDENInventors: Cornelia Sennewald, Gerald Hoffmann, Chokri Cherif
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Publication number: 20160377608Abstract: Method and arrangement for detecting binding events of molecules, in which, to at least one first molecule which is immobilised on a bioactive surface by a covalent bond, at least one second molecule has been bonded or is bonded, with formation of at least one specific non-covalent bond, the second molecule being bonded or having been bonded chemically covalently to a ligand. The bioactive surface can be contacted with at least one analyte molecule, binding events between the analyte molecule and the ligand being able to be detected by means of an analytical measuring method. The at least one specific non-covalent bond between the first and second molecule is breakable again by supplying a buffer solution. According to the invention, a third molecule is bonded to the second molecule, the third molecule also having a ligand.Type: ApplicationFiled: July 2, 2014Publication date: December 29, 2016Applicant: TECHNISCHE UNIVERSITAET DRESDENInventors: Weilin LIN, Robert WIEDUWILD, Luca MANNOCCI, Jana HERRMANN, Yixin ZHANG, Francesco REDDAVIDE
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Patent number: 9528046Abstract: In a method for producing a substrate for soil improvement with water-storing property on the basis of lignin, lignin is provided and oxidized alternatively in an aqueous alkaline or a pH-neutral aqueous suspension, wherein the pH-neutral aqueous suspension after oxidation of the lignin is converted into an alkaline medium. The lignin is cross-linked in an aqueous alkaline medium by multi-functional compounds. Subsequently, the lignin is neutralized, dried, and comminuted. The produced lignin is used as a substrate for improvement of soil properties in that the substrate is used as a water storage that, compared to water storages of non-modified technical lignins, exhibits a significantly higher water adsorption capacity or swelling capacity.Type: GrantFiled: January 14, 2015Date of Patent: December 27, 2016Assignee: Technische Universität DresdenInventors: Lars Passauer, Falk Liebner, Klaus Fischer, Joachim Katzur
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Publication number: 20160362736Abstract: A method for the deconvolution of nucleic acid-containing substance mixtures using synthetically generated target nucleotide sequences. Starting from a plurality of nucleotides,, a plurality of different target nucleotide sequences (TNS) is generated according to a predetermined algorithm. At least one of the TNS generated is associated with at least one substance or substance combination and chemically coupled thereto. At least one substance mixture to be analysed and having at least two different TNS is provided and is sequenced according to a sequencing method., at the same time all TNS contained in the substance mixture are detected in a common sequence spectrum. To facilitate the deconvolution, the sequence spectra of a substance mixture should be deducted/subtracted from each other prior to and after a selection experiment.Type: ApplicationFiled: January 12, 2015Publication date: December 15, 2016Applicant: TECHNISCHE UNIVERSITAET DRESDENInventors: Yixin ZHANG, Jana HERRMANN, Robert WIEDUWILD, Annett BODEN
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Patent number: 9496496Abstract: The invention relates to a method for producing an electrode layer of an electrical device, wherein the method includes the following steps: providing a quantity of nanoparticles from an electrically conductive material, the surfaces of each of which have a layer of a hygroscopic stabilizer material, preparing a substrate and producing an electrode layer on a substrate surface, wherein the nanoparticles in this context are deposited on the substrate surface and are tempered in a solvent atmosphere of a polar solvent.Type: GrantFiled: September 29, 2015Date of Patent: November 15, 2016Assignee: TECHNISCHE UNIVERSITÄT DRESDENInventors: Nelli Weiss, Lars Mueller-Meskamp, Jan Ludwig Bormann, Franz Selzer, David Kneppe, Nikolai Gaponik, Alexander Eychmueller
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Patent number: 9487585Abstract: The invention relates to a composition which contains at least one anti-slan antibody and to its diagnostic and therapeutic use. The composition according to the invention comprises: a) at least one anti-slan antibody, b) at least one binding unit which binds to a co-stimulus binding to a co-stimulus-specific receptor on dendritic cells, thereby bringing about the modulation, preferably the activation, of said dendritic cells, and c) at least one antigen. The invention furthermore comprises anti-slan antibodies which include CDRs with the following sequences: variable region of the heavy chain: CDR1 (SEQ ID No. 1), CDR2 (SEQ ID No. 2), where Xaa is selected from among M, L, F, or I, preferably from among M or I, CDR3 (SEQ ID No. 5) and variable region of the light chain: CDR1 (SEQ ID No. 6), where Xaa is selected from among S, T, N, Q, H, K or R, preferably from among S or N, CDR2 (SEQ ID No. 9) and CDR3 (SEQ ID No. 10).Type: GrantFiled: August 5, 2011Date of Patent: November 8, 2016Assignee: Technische Universität DresdenInventors: Michael Bachmann, Daniel Gräfe
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Publication number: 20160297718Abstract: The invention relates to a process for producing metal-coated inorganic particles by means of currentless deposition technique in which the inorganic particles are first functionalized, then introduced into an aqueous metal-salt solution containing metal ions, and the metal is reduced by adding a reducing agent to the aqueous metal-salt mixture containing the functionalized particles and the metal is deposited on the functionalized particles, wherein the functionalization of the inorganic particles takes place by means of aminophosphonic acids, aminocarboxylic acids and/or aminoalcohol phosphoric acid esters, and the aminophosphonic acid, the aminocarboxylic acid and/or the aminoalcohol phosphoric acid ester form(s) a monolayer on the surface of the inorganic particles. The metal-coated inorganic particles can be introduced into metal matrices due to their improved surface properties.Type: ApplicationFiled: November 27, 2014Publication date: October 13, 2016Applicant: TECHNISCHE UNIVERSITÄT DRESDENInventors: Giovanni MONDIN, Florian WISSER, Susanne DÖRFLER, Stefan KASKEL
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Patent number: 9428754Abstract: The invention relates to the use of a protein with recombinase activity to catalyze a site-specific DNA recombination and a method for producing a site-specific DNA recombination. The invention is applicable alone or in combination with other recombinase systems for genetic manipulation, for example in medical research. The objective of the invention is solved by the use of a protein with recombinase activity to catalyze a site-specific DNA recombination at, preferably at two, recognition sites that are identical or reverse complementary to each other. The invention also includes a method for producing a site-specific DNA recombination comprising the steps of a) providing a cell comprising at least two recognition sites that are identical or reverse complementary to each other; and b) contacting a protein with recombinase activity with the recognition sites, thereby producing the site-specific DNA-recombination.Type: GrantFiled: July 22, 2013Date of Patent: August 30, 2016Assignee: Technische Universität DresdenInventors: Frank Buchholz, Madina Karimova
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Publication number: 20160202172Abstract: The present invention relates to a method and an apparatus for sorting cells. The apparatus for determining the mechanical properties of cells comprises: —a microfluidic channel having an inlet and an outlet, the channel being configured to let a fluid containing cells pass therethrough, —a means for introducing a fluid containing cells into the channel so as to establish a flow of the fluid within the channel, —a cell shape measurement device arranged to obtain information of a deformed shape of a cell deformed due to the flow pattern created by the interaction of the fluid flow with the channel, and —an analysis means arranged to use data from the cell shape measurement device to obtain mechanical properties of the cells.Type: ApplicationFiled: June 26, 2014Publication date: July 14, 2016Applicant: Technische Universität DresdenInventors: Jochen Guck, Oliver Otto, Philip Rosendahl
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Publication number: 20160200003Abstract: The invention relates to a device for heating preform bodies or flat or preformed semi-finished products from thermoplastic material (3), comprising at least one base body (1.0, 2.0), on the surface of which at least a first layer or coating is formed, which comprises at least one electric heating resistor in the form of a flat, geometrically arranged conductor loop. The base body also has contact elements, by which the at least one heating resistor can be connected to a power source, wherein, as a result of the geometrically arranged conductor loop(s), a defined temperature profile can be generated, which can be transmitted contactlessly to the preform body or the semi-finished product by an outer contact layer formed on the first layer or coating, by contact with the surface of a preform body or semi-finished product and/or by using convection or thermal radiation.Type: ApplicationFiled: June 24, 2014Publication date: July 14, 2016Applicant: Technische Universitaet DresdenInventors: Ronald CLAUS, Marcus STEIN, Sascha BACH
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Publication number: 20160194030Abstract: Longitudinal members for motor vehicles may generally include a supporting element that is releasably connectable to an energy absorption mechanism. The supporting element may typically include a joining zone that can be used to secure the supporting element to one or more chassis or drive components of the motor vehicle. The supporting element and the energy absorption mechanism may be comprised of fiber-reinforced plastic. More specifically, the supporting element may be comprised of a plurality of length portions having different fiber orientations. For example, a first length portion may have fibers oriented substantially parallel to a horizontal longitudinal plane about which the supporting element is positioned, whereas a second length portion between the first length portion and the energy absorption mechanism may have intersecting fibers oriented oblique to the horizontal longitudinal plane.Type: ApplicationFiled: May 21, 2014Publication date: July 7, 2016Applicants: THYSSENKRUPP STEEL EUROPE AG, TECHNISCHE UNIVERSITÄT DRESDEN, LEICHTBAU-ZENTRUM SACHSEN GMBHInventors: Lothar PATBERG, Stefan MAYER, Torsten KRAHNERT, Werner HUFENBACH, Enrico LADUSCH, Jens WERNER, André KIEßLING, Alexander HERBIG, Jörn KIELE, Martin LEPPER
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Publication number: 20160129940Abstract: The present disclosure relates to a protective apparatus that can be positioned along an underside of a motor vehicle and, in many cases, near a front or rear region of the motor vehicle. The protective apparatus may include an underbody made from fiber-reinforced plastic for protecting assemblies or components arranged above it against damage as a consequence of stone chipping or ground contact. Further, the underbody may have three-dimensionally structured regions for increasing its rigidity, and the underbody may be designed to absorb chassis and/or crash loads and may include integrated holders for movably attaching chassis links.Type: ApplicationFiled: May 21, 2014Publication date: May 12, 2016Applicants: THYSSENKRUPP STEEL EUROPE AG, TECHNISCHE UNIVERSITÄT DRESDEN, LEICHTBAU-ZENTRUM SACHSEN GMBHInventors: Lothar PATBERG, Stefan MAYER, Torsten KRAHNERT, Werner HUFENBACH, Enrico LADUSCH, Jens WERNER, André KIEßLING, Alexander HERBIG, Jörn KIELE, Martin LEPPER
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Patent number: 9272281Abstract: The invention relates to a microfluidic micromechanical system having integrated active elements (7) and a method for microfluidic process control in a microfluidic micromechanical system. According to the invention, the microfluidic system comprises integrated active elements (7), which can be activated without auxiliary energy by means of ambient variables that can be influenced and which are designed to bring about active functions as a result of the change of the swelling state thereof or the mechanical properties thereof. The microfluidic micromechanical system further comprises at least one structural support (2) having at least one first (3) and one second (4) channel, wherein a reaction chamber (6) bounded by active elements (7) is formed in an overlapping region (5) of the first and second channels.Type: GrantFiled: April 11, 2013Date of Patent: March 1, 2016Assignee: Technische Universität DresdenInventors: Andreas Richter, Rinaldo Greiner, Merle Allerdissen
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Patent number: 9265861Abstract: The invention relates to novel composite materials based on a collagen matrix mineralized with silicate and calcium phosphate phases, to a method for the production thereof and use thereof as an implant material which can be shaped in a plurality of ways, a biological coating or active substance carrier. The claimed composite material comprises a collagen matrix which is mineralized with silicate and a calcium phosphate phase, said collagen being a recombinate collagen, collagen from Eumetazoa, sponge collagen from a sponge of the Demospongia class (horn sponges) or Calcarea (calcareous sponges), a synthetic collage analog, a collagen derivative or a mixture of said collagens.Type: GrantFiled: September 11, 2009Date of Patent: February 23, 2016Assignee: Technische Universität DresdenInventors: Sascha Heinemann, Hartmut Worch, Thomas Hanke
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Patent number: 9267542Abstract: The invention relates to a system of sliding elements which are formed by a base body and a counter-body. It is the object of the invention to provide a system of sliding element comprising a base body and a counter-body which has a reduced mass with a sufficient strength and which achieves improved properties of friction and wear. The system of sliding elements in accordance with the invention is formed by a counter-body and a base body as friction partners. The base body is formed from a fiber-reinforced polymer material and the counter-body is coated with diamond-like carbon at the surface subject to friction. At least the base body is formed from a textile-reinforced polymer matrix structure.Type: GrantFiled: March 28, 2012Date of Patent: February 23, 2016Assignees: Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V., Technische Universität DresdenInventors: Hans-Joachim Scheibe, Michael Leonhardt, Andreas Leson, Werner Hufenbach, Manuela Andrich, Klaus Kunze
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Patent number: 9260397Abstract: The present invention relates to salts comprising novel aryl-alkyl-substituted imidazolium and triazolium cations and arbitrary anions. The invention further relates to methods for the chemical conversion and separation of substances, comprising the salts according to the invention as solvents, solvent additives, or extraction means, and to the use of the salts according to the invention, for example as solvents or solvent additives in chemical reactions, as extracting agents for the separation of substances, or for storing hydrogen.Type: GrantFiled: January 30, 2009Date of Patent: February 16, 2016Assignee: TECHNISCHE UNIVERSITAET DRESDENInventors: Thomas Strassner, Sebastian Ahrens
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Publication number: 20160022501Abstract: A fingerstall, in particular for treatment of defects of the distal phalanx of the finger with a closed distal end, an open proximal end, and an interior. Provision is made that a chamber is formed 5 in the fingerstall at the distal end thereof, wherein the chamber is in liquid communication with the interior of the fingerstall.Type: ApplicationFiled: March 13, 2014Publication date: January 28, 2016Applicant: TECHNISCHE UNIVERSITÄT DRESDENInventors: Jurek SCHULTZ, Guido FITZE