Abstract: A Veress needle includes an outer needle having a shaft and a sharp distal point. The sharp distal point and a distal portion of the shaft are configured to penetrate tissue. A spring-loaded, inner cannula is disposed in the outer needle. The cannula has a dull tip and a gas exit aperture is formed near a distal end of the cannula. The outer needle has an outwardly expandable portion located on the distal portion of the shaft.
Type:
Application
Filed:
August 13, 2013
Publication date:
July 30, 2015
Applicant:
TEL-HASHOMER-MEDICAL RESEARCH, INFRASTRUCTURE AND SERVICES LTD.
Inventors:
Avinoam Nevler, Chaya Schwartz, Nir Horesh, Gil Har-Zahav
Abstract: The invention relates to methods for detecting an altered susceptibility to breast and ovarian cancer in a subject carrying a BRCA mutation, comprising determining the nucleic acid sequence of a polymorphism of a microRNA-related gene.
Type:
Grant
Filed:
November 30, 2009
Date of Patent:
July 28, 2015
Assignees:
Rosetta Genomics Ltd., Tel Hashomer Medical Research Infrastructure and Services Ltd.
Abstract: A method of processing an image having a plurality of picture-elements is disclosed. The method comprises: preprocessing the image to selectively enhance contrast of some picture-elements of the image, and employing a companding procedure for the preprocessed image, thereby providing a processed image. The contrast enhancement optionally and preferably features a mapping function having a plateau region for diminishing image data with intensity levels below an intensity threshold, thereby providing a preprocessed image.
Type:
Grant
Filed:
October 12, 2010
Date of Patent:
July 28, 2015
Assignees:
Ramot at Tel-Aviv University Ltd., Tel HaShomer Medical Research Infrastructure and Services Ltd.
Abstract: Disclosed are methods useful for providing information useful in the diagnosis of gastrointestinal abnormalities as well as ingestible devices useful for providing information useful in the diagnosis of gastrointestinal abnormalities.
Type:
Application
Filed:
March 16, 2015
Publication date:
July 2, 2015
Applicant:
TEL HASHOMER MEDICAL RESEARCH INFRASTRUCTURE AND SERVICES, LTD.
Abstract: The present invention provides a method for classification of kidney tumors through the analysis of the expression patterns of specific microRNAs and nucleic acid molecules relating thereto. Classification according to a microRNA expression framework allows optimization of treatment, and determination of specific therapy.
Type:
Grant
Filed:
March 5, 2012
Date of Patent:
June 30, 2015
Assignees:
Rosetta Genomics Ltd., Tel Hashomer Medical Research Infrastructure and Services Ltd.
Abstract: Disclosed are methods useful for providing information useful in the diagnosis of gastrointestinal abnormalities as well as ingestible devices useful for providing information useful in the diagnosis of gastrointestinal abnormalities.
Type:
Application
Filed:
March 5, 2015
Publication date:
June 25, 2015
Applicant:
TEL HASHOMER MEDICAL RESEARCH INFRASTRUCTURE AND SERVICES, Ltd.
Abstract: A prosthetic mitral valve with a frame comprises at least one arm shaped to deploy among a region of chordae tendineae of the native mitral valve to deflect these chords in order to pull the native valve leaflets around the frame to avoid paravalvular leaks. The frame may be made from two parts that are connected by sutures. The prosthetic valve may be deployed by a catherer comprising a deployment clamp attached to the valve frame where the deployment clamp is actuable to induce rotation of the frame.
Type:
Application
Filed:
May 20, 2013
Publication date:
June 25, 2015
Applicants:
Tel Hashomer Medical Research Infrastructure and Services Ltd., MitralHeal Ltd.
Abstract: Compositions comprising an isolated peptide, which may for example optionally comprise a sequence comprising FNFDWY (SEQ ID NO: 5), or any cyclized version thereof, and methods of using same, including for treatment of or prevention of formation of microbial biofilms and against adhesion of a cell to a surface.
Type:
Grant
Filed:
September 3, 2013
Date of Patent:
June 2, 2015
Assignee:
Tel Hashomer Medical Research, Infrastructure and Services Ltd, the Technology Transfer Company of Chaim
Abstract: Compositions comprising an isolated peptide, which may for example optionally comprise a sequence selected from the group consisting of YDYNWY (SEQ ID NO: 1), YDYNLY (SEQ ID NO: 2), YDYSFY (SEQ ID NO: 63), FDYNFY (SEQ ID NO: 3), FDYNLY (SEQ ID NO: 4), FDYNWY (SEQ ID NO: 5), YDWNLY (SEQ ID NO: 6), YDWHLY (SEQ ID NO: 7) and WDYNLY (SEQ ID NO: 8), extracted from organisms such as aquatic organisms and moss or any other sequence described herein, and methods of using same, including for treatment of or prevention of formation of microbial biofilms and against adhesion of a cell to a surface.
Type:
Grant
Filed:
September 23, 2009
Date of Patent:
May 12, 2015
Assignee:
Tel Hashomer Medical Research, Infrastructure and Services Ltd.
Abstract: The present invention provides nucleic acid sequences that are used for identification, classification and diagnosis of lung cancers. The present invention further provides microRNA molecules, as well as various nucleic acid molecules relating thereto or derived therefrom, associated with specific types of lung cancers.
Type:
Application
Filed:
December 16, 2014
Publication date:
April 9, 2015
Applicants:
ROSETTA GENOMICS LTD., TEL HASHOMER MEDICAL RESEARCH INFRASTRUCTURE AND SERVICES LTD.
Abstract: The present invention relates to methods for diagnosing, staging, prognosticating and treating melanoma based on evaluating the expression of specific patterns of oncogenic or suppressive microRNA (miR) molecules in a patient in need thereof.
Type:
Grant
Filed:
August 1, 2011
Date of Patent:
March 17, 2015
Assignees:
Ramot at Tel Aviv University Ltd., Tel Hashomer Medical Research Infrastructure and Services Ltd.
Inventors:
Gal Markel, Eyal Greenberg, Noam Shomron, Liat Edry, Jacob Schachter
Abstract: Provided is a method for improving day photopic vision and/or cone-derived visual field and visual function in a subject suffering from a retinal disease or trauma including administering to the subject a pharmaceutically effective amount of crude Dunaliella powder. Also provided is a method for improving night vision and/or rod derived visual field in a subject suffering from a retinal disease including administering to the subject a pharmaceutically effective amount of crude Dunaliella powder. A pharmaceutical composition for improving day vision and/or visual field in a subject suffering from a retinal disease including crude Dunaliella powder is also provided.
Type:
Grant
Filed:
July 18, 2013
Date of Patent:
February 24, 2015
Assignees:
Nikken Sohonsha Corporation, Tel Hashomer Medical Research Infrastructure and Services Ltd.
Inventors:
Michael Belkin, Aviv Shaish, Dror Harats, Ygal Rotenstreich
Abstract: Methods and systems for retrieving and processing medical diagnostic images are provided, comprising using picture analysis prioritization visualization and reporting system (“PAPVR system”) to determine whether each of one or more images from an image database or imaging device is of medical interest to a reviewing physician, determine whether one or more of the images is representative of the images, and provide the one or more images to a display and analysis system for review by a reviewing physician. The PAPVR system can provide the one or more images with a Key Image that is representative of the images. In addition, the PAPVR system can detect whether a patient suffers from a particular ailment, and provide a reviewing physician quantitative information that is relevant to the patient's condition.
Type:
Grant
Filed:
January 28, 2011
Date of Patent:
February 10, 2015
Assignees:
Radlogics, Inc., Tel Hashomer Medical Research and Infrastructure and Services Ltd.
Abstract: Disclosed are methods and devices useful for imaging blood-containing tissue, for example for angiography, especially retinal angiography, whereby an image is generated by dividing pixels of an image acquired at some wavelength range by corresponding pixels of an image acquired at a different wavelength range. In some embodiments, a first wavelength range includes predominantly light having wavelengths between about 400 nm and about 620 nm and a second wavelength range includes predominantly light having wavelengths between about 620 nm and about 800 nm.
Type:
Application
Filed:
February 8, 2012
Publication date:
November 20, 2014
Applicants:
TEL HASHOMER MEDICAL RESEARCH INFRASTRUCTURE AND SERVICES LTD., RAMOT AT TEL AVIV UNIVERSITY LTD.
Inventors:
Genady KOSTENICH, Arie ORENSTEIN, Michael BELKIN
Abstract: A method of treating a disease associated with a cell population which proliferates abnormally in a subject is disclosed. The method comprises administering to the subject a therapeutically effective amount of at least one modulator capable of modulating in the cell population a level and/or activity of a polypeptide having an amino acid sequence at least 60 percent similar to SEQ ID NO: 5, as determined using the Standard protein-protein BLAST [blastp] software of the NCBI.
Type:
Grant
Filed:
November 16, 2006
Date of Patent:
September 23, 2014
Assignees:
Tel Hashomer Medical Research Infrastructure and Services Ltd., The United States of America as represented by the Secretary of the Department of Health and Human Services National Institutes of Health Office of Technology Transfer
Inventors:
Shai Izraeli, Ilan R. Kirsch, Ayelet Erez, Stefano Campaner
Abstract: Apparatus for analyzing brain MRI, is disclosed. The apparatus comprises an input for receiving a first and a second MRI scans at the beginning and end of a predetermined time interval post contrast administration; a subtraction map former for forming a subtraction map from said first and said second MRI scans by analyzing said scans to distinguish between two primary populations, a slow population, in which contrast clearance from the tissue is slower than contrast accumulation, and a fast population in which clearance is faster than accumulation; and an output to provide an indication of distribution of said two primary populations, wherein said predetermined time period is at least twenty minutes.
Type:
Application
Filed:
October 18, 2012
Publication date:
September 18, 2014
Applicant:
Tel HaShomer Medical Research Infrastructure and Services Ltd.
Inventors:
Leor Zach, David Guez, David Last, Dianne Daniels, Yael Mardor
Abstract: Isolated populations of fetal renal stem cells and progenitor cells are provided. Also provided are methods of generating and using these isolated populations of cells.
Type:
Grant
Filed:
February 25, 2010
Date of Patent:
September 9, 2014
Assignee:
Tel HaShomer Medical Research Infrastructure and Services Ltd.
Abstract: The present invention provides a method for classification of kidney tumors through the analysis of the expression patterns of specific microRNAs and nucleic acid molecules relating thereto. Classification according to a microRNA expression framework allows optimization of treatment, and determination of specific therapy.
Type:
Application
Filed:
January 30, 2014
Publication date:
August 28, 2014
Applicants:
Tel Hashomer Medical Research Infrastructure and Services Ltd., Rosetta Genomics Ltd.
Inventors:
Nitzan ROSENFELD, Yael Spector, Eddie Friedman, Zohar Dotan
Abstract: The present invention relates to methods for diagnosing, staging, prognosticating and treating melanoma based on evaluating the expression of specific patterns of oncogenic or suppressive microRNA (miR) molecules in a patient in need thereof.
Type:
Application
Filed:
April 29, 2014
Publication date:
August 21, 2014
Applicants:
TEL HASHOMER MEDICAL RESEARCH INFRASTRUCTURE AND SERVICES LTD., RAMOT AT TEL AVIV UNIVERSITY
Inventors:
Gal Markel, Eyal Greenberg, Noam Shomron, Liat Edry, Jacob Schachter
Abstract: Disclosed are methods and devices comprising an elongated probe for the in vivo detection of meconium in amniotic fluid held in an amniotic sac based on detecting the presence of Zinc-coproporphyrin I (ZnCP). ZnCP is excited at approximately 405 nm and emits characteristic fluorescence, centered at about 580 nm and less intensely at 630 nm.
Type:
Grant
Filed:
October 5, 2008
Date of Patent:
July 1, 2014
Assignee:
Tel Hashomer Medical Research Infrastructure and Services Ltd.