Patents Assigned to Texas A & M University System
  • Publication number: 20210403681
    Abstract: Vanadium oxide nanomaterials dispersed in a polymeric matrix, substrates including the vanadium oxide nanomaterials dispersed in a polymeric matrix, and related methods of making vanadium oxide nanomaterials dispersed in a polymeric matrix are described.
    Type: Application
    Filed: June 28, 2018
    Publication date: December 30, 2021
    Applicant: THE TEXAS A&M UNIVERSITY SYSTEM
    Inventors: Sarbajit BANERJEE, Kate E. PELCHER, Nathan A. FLEER, Diane G. SELLERS
  • Patent number: 11208338
    Abstract: A system containing a reactor vessel including zero valent iron media, a source of a conditioning additive, a source of a reaction additive, and a process control subsystem is disclosed. A method for reducing a concentration of one or more contaminants in contaminated water including contacting zero valent iron media with a conditioning additive, contacting contaminated water with conditioned zero valent iron media, and introducing a reaction additive is also disclosed. The conditioning additive and reaction additive may each contain an aluminum salt.
    Type: Grant
    Filed: July 31, 2019
    Date of Patent: December 28, 2021
    Assignees: Evoqua Water Technologies LLC, The Texas A&M University System
    Inventors: Yongheng Huang, Michael Wismer, Lew Andrew Reyes, Xiangyi Qiao, Simon Dukes, Frank Sassaman, David Berger
  • Patent number: 11206798
    Abstract: The present disclosure provides cotton plants with reduced gossypol levels in the seed, and in further embodiments provides cotton plants with increased gossypol levels in the leaves. Also provided are methods for reducing gossypol content in seeds of a cotton plant by down-regulation of CGF2 expression, and in certain embodiments CGF1 and/or CGF3 expression, in the plant, and methods for increasing gossypol content in leaves of a cotton plant by tissue-specific overexpression of CGF2, and in certain embodiments CGF1 and/or CGF3, in the plant.
    Type: Grant
    Filed: October 12, 2018
    Date of Patent: December 28, 2021
    Assignee: THE TEXAS A & M UNIVERSITY SYSTEM
    Inventors: Keerti S. Rathore, Madhusudhana R. Janga, Devendra Pandeya, LeAnne M. Campbell
  • Publication number: 20210395091
    Abstract: Methods and reactors for electrochemically expanding a parent material and expanded parent materials are described. Current methods of expanding parent materials incompletely-expand parent material, requiring expensive and time-consuming separation of expanded parent material from unexpanded parent materials. This problem is addressed by the methods and reactor for electrochemically expanding a parent material described herein, which during operation maintain electrical connectivity between the parent material and an electrical power source. The resulting materials described herein have a greater proportion of expanded parent material relative to unexpanded parent material compared to those made according to others methods.
    Type: Application
    Filed: June 14, 2021
    Publication date: December 23, 2021
    Applicant: The Texas A&M University System
    Inventors: Thomas C. Achee, Micah J. Green, Charles B. Sweeney, Wanmei Sun
  • Publication number: 20210395112
    Abstract: Hydrogel-based sorbents and methods for their use in collecting, concentrating, and removing environmental per- and poly-fluoroalkyl substances. In one aspect, the invention provides hydrogel-based sorbents that are effective for collecting, concentrating, and removing PFASs from an environment in which the sorbent is placed; an environment in which the sorbent is in contact with (e.g., liquid communication).
    Type: Application
    Filed: November 27, 2019
    Publication date: December 23, 2021
    Applicant: The Texas A&M University System
    Inventors: Jun Kameoka, Po-Jung Huang, Kung-Hui Chu
  • Patent number: 11198869
    Abstract: Disclosed herein are antisense oligonucleotides that are capable of inducing expression of ubiquitin-protein ligase E3A (UBE3A) from the paternal allele in animal or human neurons. The oligonucleotides target the suppressor of the UBE3A paternal allele by hybridization to SNHG14 long non-coding RNA at the 5?-end of UBE3A-AS, which is downstream of SNORD115-45 snoRNA. Also disclosed are pharmaceutical compositions and methods for treatment of Angelman syndrome.
    Type: Grant
    Filed: November 30, 2018
    Date of Patent: December 14, 2021
    Assignee: The Texas A&M University System
    Inventor: Scott Victor Dindot
  • Publication number: 20210379356
    Abstract: The present invention provides a direct cardiac compression device for individualized support at different locations around the heart, the device comprising: a housing shaped to conform to the shape of the heart and to surround the heart; two or more active chambers positioned adjacent to the housing, wherein the two or more active comprise one or more right active chambers positioned on the right ventricle side of the heart and one or more left active chambers positioned on the left ventricle side of the heart, wherein the two or more active chambers are designed to conform to the shape of the heart, each active chamber comprising an inner membrane sealingly attached along its periphery to the housing and an active fluid individually supplied thereto; a right input connection in fluid communication with the one or more right active chambers to ingress the active fluid into each of the one or more right active chambers; a left input connection in fluid communication with the one or more left active chambers t
    Type: Application
    Filed: August 5, 2021
    Publication date: December 9, 2021
    Applicants: THE TEXAS A&M UNIVERSITY SYSTEM, CORINNOVA INCORPORATED
    Inventors: John C. Criscione, Lewis D. Harrison, Michael R. Moreno, Christina M. Bolch, Dennis I. Robbins, Saurabh Biswas, Boris Leschinsky
  • Patent number: 11193513
    Abstract: In an embodiment, the present disclosure pertains to a cavitation generation device that includes a dactyl plunger rotatable about an axis between an open position and a closed position and a propus socket having a channel. The propus socket is rigidly mounted below the dactyl plunger, and the dactyl plunger is received into the propus socket when the dactyl plunger is in the closed position. The cavitation generation device can also include a torsion spring that biases the dactyl plunger into contact with the propus socket. In another embodiment, the present disclosure pertains to a method of inducing a cavitation including biasing a dactyl plunger via a torsion spring, and rotating the dactyl plunger, by action of the torsion spring, into a propus socket. The propus socket includes a nozzle-shaped channel. The method further includes ejecting a socket cavity volume through the nozzle-shaped channel thereby inducing a cavitation event.
    Type: Grant
    Filed: July 18, 2019
    Date of Patent: December 7, 2021
    Assignee: The Texas A&M University System
    Inventors: David Staack, Xin Tang
  • Patent number: 11186779
    Abstract: A pyrolysis and gasification system produce a synthesis gas and bio-char from a biomass feedstock. The system includes a feed hopper that has a flow measurement device. The system also includes a reactor that is operable in a gasification mode or a pyrolysis mode. The reactor is configured to receive the biomass feedstock from the feed hopper. The reactor is operable to provide heat to the biomass feedstock from the feed hopper to produce the synthesis gas and bio-char. The system also includes a cyclone assembly. The produced synthesis gas including the bio-char is fed to the cyclone assembly. The cyclone assembly removes a portion of the bio-char from the synthesis gas.
    Type: Grant
    Filed: July 3, 2019
    Date of Patent: November 30, 2021
    Assignee: The Texas A&M University System
    Inventors: Sergio C. Capareda, Calvin B. Parnell, Jr., David B. Carney
  • Publication number: 20210354135
    Abstract: A system for evaluating an ability of a blood sample to coagulate, clot, and/or occlude includes a microfluidic device including a body and a tortuous microchannel formed in the body, wherein the tortuous microchannel includes a plurality of alternating curves and has a tortuosity index (TI) of at least 2.0, and a pump fluidically configured to fluidically connect to the tortuous microchannel of the microfluidic device and to induce a blood flow through the tortuous microchannel at at least one of a constant pressure and a constant flowrate.
    Type: Application
    Filed: May 13, 2021
    Publication date: November 18, 2021
    Applicant: The Texas A&M University System
    Inventors: Abhishek Jain, David Jordan Luna
  • Patent number: 11160834
    Abstract: Preparations comprising an enriched population of extracellular vesicles (nEVs) having a negatively charged surface, and that are CD81+ and CD9?, are provided. Improved processes and methods for producing an enriched population of nEVs from non-murine cells, especially human origin cells and/or tissues, are disclosed. Therapeutic methods for using the preparations, including for reducing brain inflammation and treatment of various pathologies associated with brain inflammation, such as by intravenous or intranasal administration, are also described. Methods and preparations for reducing brain inflammation associated with traumatic brain injury (TBI) are also disclosed. A method for treating a patient having suffered a mild traumatic injury (mTMI), or concussion, such as a sports-related head injury, is also disclosed. The nEVs are also demonstrated to reduce the expression level of IL-I? in brain tissue of an animal having had traumatic brain injury.
    Type: Grant
    Filed: April 28, 2016
    Date of Patent: November 2, 2021
    Assignee: THE TEXAS A&M UNIVERSITY SYSTEM
    Inventors: Darwin J. Prockop, Dong-Ki Kim, Hidetaka Nishida, Askok K. Shetty
  • Publication number: 20210330840
    Abstract: A system for reducing a microbial and/or viral load on equipment using ozone includes a container including having an open configuration to provide access to an interior of the container and a closed configuration to seal the interior from an environment external the container, and wherein the interior includes a receptive region to receive the equipment, a circulation fan positioned in the interior of the container, and one or more ozone generators positioned in the interior of the container and configured to generate ozone upon activation, wherein the circulation fan is configured to provide an airflow including ozone generated by the one or more ozone generators and directed along a flowpath extending into the receptive region of the interior of the container.
    Type: Application
    Filed: April 28, 2021
    Publication date: October 28, 2021
    Applicant: The Texas A&M University System
    Inventors: David Staack, Suresh D. Pillai, Matt Pharr, Kavita Rathore, John Lassalle, Matthew L. Burnette, Min Huang, Md Kamrul Hassan
  • Publication number: 20210336636
    Abstract: A method includes receiving a first data frame and a second data frame from a communication channel; decoding the first data frame using a first portion of an extended parity-check matrix (PCM); and decoding the second data frame using a second portion of the extended PCM. The first portion is a subset of the second portion.
    Type: Application
    Filed: April 23, 2021
    Publication date: October 28, 2021
    Applicant: THE TEXAS A&M UNIVERSITY SYSTEM
    Inventors: Sina Pourjabar, Gwan Seong Choi
  • Patent number: 11141164
    Abstract: A system for treating an aneurysm in a blood vessel or vein, wherein the aneurysm has a dome, an interior, and a neck. The system includes a shape memory polymer foam in the interior of the aneurysm between the dome and the neck. The shape memory polymer foam has pores that include a first multiplicity of pores having a first pore size and a second multiplicity of pores having a second pore size. The second pore size is larger than said first pore size. The first multiplicity of pores are located in the neck of the aneurysm. The second multiplicity of pores are located in the dome of the aneurysm.
    Type: Grant
    Filed: May 18, 2017
    Date of Patent: October 12, 2021
    Assignees: Lawrence Livermore National Security, LLC, The Texas A&M University System
    Inventors: Jason M. Ortega, William J. Benett, Ward Small, Thomas S. Wilson, Duncan J. Maitland, Jonathan Hartman
  • Patent number: 11136333
    Abstract: Functionalized pyrano[2,3-d]pyrimidin-7-one derivatives, methods for making the derivatives, and methods of using the derivatives as protein kinase inhibitors.
    Type: Grant
    Filed: May 23, 2017
    Date of Patent: October 5, 2021
    Assignee: The Texas A&M University System
    Inventors: Dai Lu, Chang-Jiang Qiao, Boqiao Fu, Anantha Lakshmi Duddupudi, Zhixing Wu
  • Publication number: 20210285115
    Abstract: Processes and systems for electrochemical exfoliation that use a compression reactor and, more particularly, to processes and systems for electrochemical exfoliation of planar parent materials, such as graphite. A reactor for electrochemical exfoliation may include a container configured to hold an electrolyte solution. The reactor may further include a porous chamber, wherein the porous chamber is configured to hold a parent material in fluid communication with the electrolyte solution. The reactor may further include a pressure source positioned to apply a pressure along a length of the porous chamber to thereby compress the parent material in the porous chamber. The reactor may further include a first counter electrode. The reactor may further include a working electrode. The reactor may further include an electrical power source in electrical communication with the first counter electrode and the working electrode.
    Type: Application
    Filed: March 5, 2021
    Publication date: September 16, 2021
    Applicants: ExxonMobil Chemical Patents Inc., The Texas A&M University System
    Inventors: Rohan Ashok Hule, Micah J. Green, Joshua T. Hope, Wanmei Sun
  • Patent number: 11121211
    Abstract: A lateral superjunction includes a substrate layer, a selective epitaxy layer deposited on the substrate layer, a trench formed into the selective epitaxy layer to expose a portion of the substrate layer, a first layer of semiconductor deposited in the trench, a second layer of semiconductor deposited adjacent to the first layer, and a first end layer of semiconductor deposited adjacent to the first layer of semiconductor and a second end layer of semiconductor deposited adjacent to the second layer of semiconductor.
    Type: Grant
    Filed: September 28, 2018
    Date of Patent: September 14, 2021
    Assignee: The Texas A&M University System
    Inventors: Michael Everett Babb, Harlan Rusty Harris
  • Patent number: 11109869
    Abstract: An embodiment of the invention is a shape memory polymer (SMP) foam designed to recover its original shape through exposure to a solvent. Thermo-responsive SMPs are polymers designed to maintain a programmed secondary shape until heated above their transition temperature, upon which the polymer recovers its original, or primary, shape. The thermo-responsive SMP foam is programmed to its secondary shape prior to use, typically compression of the foam to a small volume, and remains in this programmed shape until exposed to a selected solvent such as dimethyl sulfoxide or ethyl alcohol. Upon exposure to the solvent, the transition temperature of the SMP foam decreases below the temperature of the environment and the SMP foam actuates to its primary shape. The SMP foam is tailored to actuate upon exposure to specific solvents while minimizing or preventing actuation when exposed to water or other solvents.
    Type: Grant
    Filed: January 30, 2020
    Date of Patent: September 7, 2021
    Assignees: Lawrence Livermore National Security, LLC, The Texas A&M University System
    Inventors: Anthony Boyle, Keith Hearon, Duncan J. Maitland, Landon D. Nash, Thomas S. Wilson
  • Publication number: 20210252102
    Abstract: The invention relates to methods for treating cancers by targeting the elimination of selective activated immune cell populations in combination with checkpoint inhibitors. The cells may be targeted, for instance, using CLIP inhibitors and or MHC class II inducers.
    Type: Application
    Filed: April 29, 2021
    Publication date: August 19, 2021
    Applicants: The Texas A&M University System, The Regents of the University of Colorado, a Body Corporate
    Inventors: Richard Tobin, Martha Karen Newell-Rogers
  • Publication number: 20210253232
    Abstract: A hover-capable aircraft includes a body including a tubular strut, a first rotor assembly rotatably coupled to the body and positioned about the strut, wherein the first rotor assembly includes a first plurality of circumferentially-spaced blades, a first actuation assembly including a first plurality of electronically controlled actuators coupled to a first swashplate and configured to control the movement of the first swashplate relative to the body, and a control system coupled to the body and configured to control the first plurality of actuators, wherein the control system includes a cable extending through a passage formed in the tubular strut and in signal communication with the first plurality of actuators.
    Type: Application
    Filed: June 14, 2019
    Publication date: August 19, 2021
    Applicant: The Texas A&M University System
    Inventors: Moble Benedict, David Coleman, Atanu Halder, Bochan Lee, Andrew Riha, Farid Saemi, Carl Runco, Vishaal Subramanian, Eric Greenwood, Vinod Lakshminarayan