Abstract: The present invention provides methods, systems, kits, and cardiac compression devices that have both passive chambers and active chambers to improve heart function.

Abstract: Provided herein is an electrodialysis metathesis system that has at least one stack or quad of compartments arranged so each compartment is in fluid communication with its adjacent compartment via alternating cation—and anion-exchange membranes. The compartments in a stack are a feed compartment, a substitution salt solution compartment, a first concentrated compartment and a second concentrated compartment. Also provided are processes and methods for separating or recovering a metal, for example, a rare earth element, or a salt or a combination thereof from a salt-containing water. Simultaneous metathesis reactions and electrodialysis across the stack recovers one or more metal or salts from the salt-containing water which desalinates the salt-containing water.

Abstract: A flapping-wing aircraft includes a support frame, a motor coupled to the support frame, a pair of wings coupled to the support frame, and a linkage assembly coupled to the support frame and configured to translate an output torque of the motor into flapping motion of the wings, wherein the linkage assembly includes a first link coupled to a rotational output of the motor, a second link pivotably coupled to the first link at a first pivot joint, a third link pivotably coupled to the second link at a second pivot joint, and a fourth link pivotably coupled to the support frame and slidably coupled to the third link, and wherein the fourth link is coupled to a first wing of the pair of wings.

Abstract: NR4A1 ligands, pharmaceutical compositions including the NR4A1 ligands, and related methods of use are described. Methods of treating a disease or condition in an individual treatable by modulation of NR4A1 activity, comprising administering to the individual a therapeutically effective amount of a compound or a pharmaceutical composition described herein.

Abstract: Methods, systems, and computer readable media for performing page fault handling are disclosed. According to one method, the method includes: after a translation lookaside buffer (TLB) miss associated with a virtual memory page occurs, identifying, in a page table, a page table entry (PTE) associated with the virtual memory page; determining, using a first indicator in the PTE, that the virtual memory page is not present in a main memory; determining, using a second indicator in the PTE, that the virtual memory page is associated with a valid memory address and that the virtual memory page is capable of using pre-allocated pages; obtaining, from a pre-allocation table, a page frame number associated with a pre-allocated page; and updating the PTE to indicate the page frame number.

Abstract: An electric machine includes a stator having a stator winding disposed thereon. A rotor is electromagnetically exposed to the stator. A field winding and an induction winding are disposed on the rotor. A rectifier is electrically coupled to the induction winding and the field winding. Upon application of a voltage to the stator winding, the stator winding produces a first rotating magnetic field and a second rotating magnetic field that has a different spatial frequency than the first rotating magnetic field. The first rotating magnetic field interacts asynchronously with the induction winding to produce an alternating current in the induction winding. The rectifier changes the alternating current to a direct current that is supplied to the field winding. The field winding interacts synchronously with the second rotating magnetic field.

Abstract: The present disclosure includes a fusion protein, called a “Seldeg”, including a targeting component that specifically binds to a cell surface receptor or other cell surface molecule at near-neutral pH, and an antigen component fused directly or indirectly to the targeting component. The antigen component is configured to specifically bind a target antigen-specific antibody. The present disclosure also includes a method of depleting a target antigen-specific antibody from a patient by administering to the patient a Seldeg having an antigen component configured to specifically bind the target antigen-specific antibody.

Abstract: An embodiment includes a system comprising: a monolithic shape memory polymer (SMP) foam having first and second states; wherein the SMP foam includes: (a) polyurethane, (b) an inner half portion having inner reticulated cells defined by inner struts, (c) an outer half portion, having outer reticulated cells defined by outer struts, surrounding the inner portion in a plane that provides a cross-section of the SMP foam, (d) hydroxyl groups chemically bound to outer surfaces of both the inner and outer struts. Other embodiments are discussed herein.

Abstract: The present invention provides methods and compositions to reduce binding of fibrinogen to the ClfA in a gram positive bacterial infections using monoclonal antibody, a polyclonal antibody, an antigen-binding antibody fragment or a composition that specifically binds to a portion of ClfA with the sequence of SEQ ID No: 15, SEQ ID NO: 16, SEQ ID NO: 17, and SEQ ID NO: 18.

Abstract: A method and system for decoding low density parity check (“LDPC”) codes. An LDPC code decoder includes LDPC decoding circuitry comprising a Q message generator and a P sum adder array. The Q message generator combines an R message from a previous iteration with a P message to produce a Q message. The P sum adder array adds the P message to a difference of an R message from a current iteration and the R message from the previous iteration to produce an updated P message.

Abstract: Vaccine vectors and methods of using the vaccine vectors to enhance the immune response to an Apicomplexan parasite and reduce the morbidity or mortality associated with subsequent infection are provided herein. The vaccine vectors include a polynucleotide encoding a Rhomboid polypeptide and optionally include an immune-stimulatory polypeptide suitably expressed on the surface of the vaccine vector.

Abstract: The present disclosure relates, according to some embodiments, to pathogen resistant plants, compositions, organisms, systems, and methods. For example, a composition may comprise a heterologous peptide (e.g., a defensin peptide) and/or a nucleic acid (e.g., a defensin nucleic acid). A pathogen resistant plant may comprise, in some embodiments, a heterologous defensin peptide and/or an expressible nucleic acid encoding a heterologous defensin peptide.

Abstract: The present disclosure provides a recombinant viral vector comprising at least one transgene inserted into a Marek's disease viral genome for treatment of diseases in poultry. Also provided are immunogenic compositions comprising such recombinant viral vectors and methods for preventing or inhibiting Marek's disease in combination with at least a second disease in poultry.

Abstract: In an embodiment, a device for modulating intracellular gene expression, the device having a calcium actuator component and a transcription reprogramming component. In another embodiment, a method for modulating intracellular gene expression, where the method includes inducing a system having a calcium actuator component and a transcription reprogramming component with at least one of light and a chemical, causing an increase in Ca2+, and translocating the transcription reprogramming component from cytosol to the nucleus.

Abstract: An instrument for energizing molecules contained in a sample solution may include a droplet generator configured to generate droplets of the sample solution. The droplet generator illustratively has an elongated nozzle defining an orifice at one end thereof from which the droplets exit the droplet generator, and the orifice illustratively defines a first longitudinal axis centrally therethrough. A molecule energizing source is configured to produce a molecule energizing field, and is positioned relative to the nozzle orifice such that the molecule energizing field extends into at least some of the generated droplets along a direction non-parallel with the first longitudinal axis. The molecule energizing field illustratively carries energy which heats at least one of the generated droplets sufficiently to induce structural changes in at least one molecule contained in the at least one of the generated droplets.

Abstract: Embodiments of the present disclosure pertain to methods of constructing a phage display library where at least 90% of combinatorial regions in the phage display library include at least one in-frame amber codon. Further embodiments of the present disclosure pertain to the formed phage display libraries. Additional embodiments of the present disclosure pertain to methods of selecting peptides or proteins that bind to a desired target (e.g., a ligand binding site of a desired target) by utilizing the phage display libraries of the present disclosure. Further embodiments of the present disclosure pertain to peptides that have been screened from the phage display libraries and methods of the present disclosure, such as inhibitors of sirtuin 2, or inhibitors of ENL.

Abstract: Hydrocarbon conversion and transportation methods and apparatuses are provided. An apparatus may apply electron beam irradiation to hydrocarbons (i.e., natural gas) to convert the hydrocarbons to liquid fuel. Lower-weight hydrocarbons may be converted into medium-weight organics through a gas to liquid process (GTL). The electrons may generate radicals that facilitate desired reactions. The hydrocarbons may be temperature and pressure controlled. For example, the hydrocarbons may be at lower temperatures (e.g., cryogenic or otherwise below ambient) and/or at higher pressures (e.g., greater than standard atmospheric pressures). Temperature suppression may reduce decomposition reactions. A high energy electron beam (e.g., 500 keV or higher, such as 10 MeV) could be used for the conversion process. The hydrocarbon may be liquefied. The liquid-like, higher density lower-weight hydrocarbons may lead to radical-neutral interactions.

Abstract: A biodegradable and biocompatible three dimensional construct comprising a combination of a nano silicate (e.g., laponite) and two different polymers, the two polymers each individually providing at least one covalently linked polymer chain and at least one ionically linked polymer chain, the polymeric chains forming a dual strengthening intertwined polymeric system. The constructs demonstrate improved mechanical and strength properties, while the bioinks provide a material having superior printability characteristics suitable for printing a three dimensional biodegradable construct having an aspect ratio of greater than 2.0. The bioink may also comprise cells or combinations of cells. Methods of using the constructs and bioinks for wound healing preparations and tissue regeneration are also provided.

Abstract: A method of electrochemical exfoliation, may include: electrochemically exfoliating a parent material comprising coke, wherein the electrochemically exfoliating comprises introducing the parent material into a porous chamber, applying pressure to the porous chamber to thereby compress the parent material in the porous chamber, and applying a potential bias to the parent material while at least a portion of the parent material is in contact with an electrolyte solution to produce a mixture of exfoliated material and unexfoliated parent material, wherein the exfoliated material comprises exfoliated graphene; and separating at least a portion of the exfoliated material from the unexfoliated parent material.

Abstract: ‘DALBG 1201’ is an F1 hybrid bluegrass with exceptional turfgrass quality, dark green color, high shoot density, medium-fine leaf texture, and ability to persist under a range of environmental stresses typically encountered in the southern United States.