Patents Assigned to Texas Tech University System
  • Patent number: 11712822
    Abstract: A microwave-induced heating of CNT filled (or coated) polymer composites for enhancing inter-bead diffusive bonding of fused filament fabricated parts. The technique incorporates microwave absorbing nanomaterials (carbon nanotubes (CNTs)) onto the surface or throughout the volume of 3D printer polymer filament to increase the inter-bead bond strength following a post microwave irradiation treatment and/or in-situ focused microwave beam during printing. The overall strength of the final 3D printed part will be dramatically increased and the isotropic mechanical properties of fused filament part will approach or exceed conventionally manufactured counterparts.
    Type: Grant
    Filed: July 19, 2019
    Date of Patent: August 1, 2023
    Assignee: Texas Tech University System
    Inventors: Charles B. Sweeney, Micah J. Green, Mohammad Saed
  • Patent number: 11709316
    Abstract: An optical waveguide includes a first waveguide core, a second waveguide core, a first subwavelength multilayer cladding, a second subwavelength multilayer cladding and a third subwavelength multilayer cladding. The first waveguide core and the second waveguide core have a width (w) and a height (h). The first waveguide core is disposed between the first subwavelength multilayer cladding and the second subwavelength multilayer cladding. The second waveguide core is disposed between the second subwavelength multilayer cladding and the third subwavelength multilayer cladding. Each subwavelength multilayer cladding has a number (TV) of alternating subwavelength ridges having a periodicy (A) and a filling fraction (p). A total coupling coefficient (|/c|) of the first waveguide core and the second waveguide core is from 10 to 0.
    Type: Grant
    Filed: February 23, 2021
    Date of Patent: July 25, 2023
    Assignee: Texas Tech University System
    Inventors: Sangsik Kim, Md Borhan Mia
  • Publication number: 20230228766
    Abstract: The present disclosure pertains to predicting an onset of a cerebral hemorrhagic event in a subject by testing a blood sample of the subject for the presence or absence of one or more indicators; and correlating the presence or absence of the one or more indicators to the subjects risk for suffering from the cerebral hemorrhagic event, where the presence of the one or more indicators is correlated to an increased risk in the subject for suffering from the cerebral hemorrhagic event and where the absence of the one or more indicators is correlated to a decreased risk in the subject for suffering from the cerebral hemorrhagic event. The methods of the present disclosure may also include implementing a therapeutic decision in order to prevent the cerebral hemorrhagic event. The present disclosure also pertains to kits for use in predicting an onset of a cerebral hemorrhagic event in a subject.
    Type: Application
    Filed: June 4, 2021
    Publication date: July 20, 2023
    Applicant: Texas Tech University System
    Inventors: Jun Zhang, Johnathan Abou-Fadel
  • Publication number: 20230210076
    Abstract: Embodiments of the present disclosure pertain to modified plants or seeds that include: (1) overexpressed rice SUMO E3 ligase SIZ1 (OsSIZ1), an analog thereof, a homolog thereof, a derivative thereof, or combinations thereof; and (2) overexpressed Larrea tridentate rubisco activase (LtRCA), an analog thereof, a homolog thereof, a derivative thereof, or combinations thereof. The modified plant or seed demonstrates enhanced resistance to environmental stress. Additional embodiments of the present disclosure pertain to methods of developing a modified plant or seed of the present disclosure by overexpressing in the plant or seed: (1) rice SUMO E3 ligase SIZ1 (OsSIZ1), an analog thereof, a homolog thereof, a derivative thereof, or combinations thereof; and (2) Larrea tridentate rubisco activase (LtRCA), an analog thereof, a homolog thereof, a derivative thereof, or combinations thereof. Further embodiments pertain to methods of growing a modified plant or seed of the present disclosure in a field.
    Type: Application
    Filed: December 20, 2022
    Publication date: July 6, 2023
    Applicant: Texas Tech University System
    Inventor: Hong Zhang
  • Publication number: 20230165486
    Abstract: A method of analyzing a subject using a dynamo torque analyzer includes recording the force produced during an isometric contraction of the subject with a load cell, processing data associated with the isometric contraction, and calculating and displaying, via a microcomputer of the dynamo torque analyzer, peak torque, and rate of torque development values using the data associated with the isometric contraction. The dynamo torque analyzer calculates and displays the peak torque and rate of torque development values in real time.
    Type: Application
    Filed: February 25, 2021
    Publication date: June 1, 2023
    Applicant: Texas Tech University System
    Inventors: Ty Palmer, Jarrod Blinch
  • Publication number: 20230157281
    Abstract: In an embodiment, the present disclosure pertains to a method of repelling an animal from an object by applying a composition to the object. In some embodiments, the animal is from the felidae species. In some embodiments, the composition includes butanoic acid and 3-Mercapto-3-Methyl Butanol (MMB). In an additional embodiment, the present disclosure pertains to a composition for repelling an animal from an object. In some embodiments, the animal is from the felidae species. In some embodiments, the composition includes butanoic acid and MMB.
    Type: Application
    Filed: March 24, 2021
    Publication date: May 25, 2023
    Applicant: Texas Tech University System
    Inventor: John J. McGlone
  • Patent number: 11647760
    Abstract: The present invention includes a method and meat product made by contacting an emulsion with a meat product for a time sufficient to, wherein the emulsion comprises by weight: 10% to 50% water, 0.1 to 4.0% Quillaja, 0.1% to 8% meat flavoring, 60% to 85% high oleic sunflower oil, meat seasoning, 0-2.0% salt, and optionally one or more stabilizers.
    Type: Grant
    Filed: November 5, 2018
    Date of Patent: May 16, 2023
    Assignee: Texas Tech University System
    Inventor: Richard Schlomer Meyer
  • Patent number: 11649707
    Abstract: Methods for optimization of liquid oil production by huff-n-puff in shale reservoirs to achieve an improved (and optimal) oil recovery factor. The process determines and utilizes the optimum huff and puff times, number of cycles and soaking time under practical operation and reservoir conditions. The huff time in the process is a period so long that the pressure near the wellbore reaches the set maximum injection pressure during the huff period. The puff time in the process is the time required for the pressure near the wellbore to reach the set minimum production pressure during the puff period. Soaking is typically not necessary during the huff-n-puff gas injection in shale oil reservoirs. The number of huff-n-puff cycles is determinable by the time in which the economic rate cut-off is reached.
    Type: Grant
    Filed: April 2, 2021
    Date of Patent: May 16, 2023
    Assignee: Texas Tech University System
    Inventor: James J. Sheng
  • Publication number: 20230111468
    Abstract: The present disclosure provides using ultrasound technology and artificial intelligence to enhance MSR assessment by making the assessment more objective, reproducible, and recordable to allow a more precise and/or personalized approach to the medical practice of individual patients via using multiple ultrasound functions and artificial intelligence to improve the accuracy and consistency of assessing reflexes and allowing MSR data to be combined with other patient medical information for improved diagnosis and management of a patient's condition.
    Type: Application
    Filed: December 13, 2022
    Publication date: April 13, 2023
    Applicants: University of South Carolina, Texas Tech University System
    Inventors: Richard Hoppmann, Jongyeol Kim
  • Patent number: 11623076
    Abstract: The present invention includes a medicated dental floss and a method of making a medicated dental floss comprising: stretching a dental floss; dipping the dental floss in a biocompatible polymer—solvent bath to coat the braided dental floss; drying the coated braided dental floss; dipping the coated dental floss in a medicated solution comprising an encapsulated medicament; and drying the medicated encapsulant on the coated dental floss.
    Type: Grant
    Filed: May 1, 2019
    Date of Patent: April 11, 2023
    Assignee: Texas Tech University System
    Inventors: Harvinder Singh Gill, Seth Boese
  • Publication number: 20230105761
    Abstract: The present disclosure describes a self-sprayer device for self-administering an animal product to an animal and providing environmental enrichment to the animal.
    Type: Application
    Filed: October 4, 2022
    Publication date: April 6, 2023
    Applicant: Texas Tech University System
    Inventor: John J. McGlone
  • Patent number: 11591597
    Abstract: The present invention includes methods for detecting and reducing or inhibiting ischemic stroke in a mammal, the method comprising: (a) selecting microRNAs to downregulate selected from the group consisting of hsa-miR-96-5p, hsa-miR-99a-5p, hsa-miR-122-5p, hsa-miR-186-5p, hsa-miR-211-5p, hsa-mir-760, PC-3p-57664, or PC-5p-12969, (b) selecting microRNAs to upregulate selected from the group consisting of ggo-miR-139, hsa-miR-30d-5p, hsa-miR-22-3p, hsa-miR-23a-3p, mmu-miR-5124a, mmu-mir-6240-5p, PC-3p-32463, or PC-5p-211, and combinations thereof, and (c) administering an agent that: downregulates that targets in (a), upregulates the targets in (b), or both, to the subject in an amount sufficient to reduce or inhibit ischemic stroke in the mammal. The present invention also includes the detection of the markers for use with stroke patients.
    Type: Grant
    Filed: April 18, 2019
    Date of Patent: February 28, 2023
    Assignee: Texas Tech University System
    Inventors: P. Hemachandra Reddy, Murali Vijayan
  • Patent number: 11592436
    Abstract: Disclosed is a system and device for determining sex of an embryo utilizing a non-invasive grading of early stage embryos (pre-hatching) based upon specific gravity, density and/or estimated weight. The device comprises a drop chamber having a lumen, capable of assessing characteristics of at least one embryo while descending. The system allows 100% recovery of embryos. A processor is further capable of performing assessment of the embryos. The disclosed system supports a wide variety of scenarios for human and animal reproductive technologies and related products and services.
    Type: Grant
    Filed: March 29, 2019
    Date of Patent: February 28, 2023
    Assignee: Texas Tech University System
    Inventors: Samuel D. Prien, Lindsay L. Penrose, Cara E. Wessels
  • Patent number: 11579137
    Abstract: Disclosed is a system and method for extraction of information of within sample distribution of fiber quality from high-volume instrument (HVI) fibrogram to better predict yarn quality than the standard HVI output. The present invention allows for information on fiber quality to be obtained while avoiding testing samples with more expensive techniques. The disclosed system and method extracts HVI data for collecting a respective set of initial fibrograms from a set of fiber samples and representing them as a distance matrix to form a matrix of transformed fibrogram data, said matrix of transformed fibrogram data comprising a vector of scores to represent each sample and thereafter explaining variation in yarn quality by extracting all of the information available from the fibrogram.
    Type: Grant
    Filed: November 13, 2018
    Date of Patent: February 14, 2023
    Assignee: Texas Tech University System
    Inventors: Brendan Kelly, Eric Hequet, Md Abu Sayeed, Zach Hinds
  • Patent number: 11560575
    Abstract: The present invention includes synthesis of polyethyleneimine800-EpoxyC8-22 (PEI800-C8-22) lipids, e.g., Polyethyleneimine800-EpoxyC16 (PEI800-C16), PEI12C16, PEI8C16, and PEI4C16 lipids, compositions and methods for transfecting primary leukocytes, myeloid cells, lymphoid cells, monocytes, macrophages and dendritic cells (DC) comprising a transfection complex comprising: one or more nanoparticles; and Polyethyleneimine800-EpoxyC16 (PEI800-C16), PEI12C16, PEI8C16, and PEI4C16 lipids complexed with one or more nucleic acids, such as, e.g., DNA, RNA, nucleic acid vectors, shRNA, miRNA, and RNAi on or about the nanoparticles.
    Type: Grant
    Filed: December 3, 2018
    Date of Patent: January 24, 2023
    Assignee: Texas Tech University System
    Inventor: Huanyu Dou
  • Patent number: 11560413
    Abstract: The present invention is directed to modified CFTR proteins or fragments thereof that contain single or multiple amino acid mutations to improve the structural stability of such CFTR proteins and/or fragments. Specifically, the modified CFTR proteins or fragment thereof differ from the wild-type human CFTR protein or fragment thereof by the presence of four or more mutations selected from V150D, M470V, S492P, F494N, S495P, A534P, I539T, G550E, G551D, R553Q, R555K, Q637R, S1255L, K1334G, S1359A, E1371Q, H1402S, Q1411D, and any combination thereof, such that the stability of the polypeptide is increased relative to that of the wild-type human CFTR polypeptide or fragment thereof.
    Type: Grant
    Filed: February 15, 2019
    Date of Patent: January 24, 2023
    Assignees: UAB Research Foundation, Texas Tech University System
    Inventors: John C. Kappes, Zhengrong Yang, Christie G. Brouillette, Ina L. Urbatsch
  • Patent number: 11542227
    Abstract: A method of treating Alcohol Use Disorder (AUD), Substance Use Disorder (SUD), tobacco use, pain, or proinflammatory disorders comprising: providing a subject with an effective amount of a modified tetracycline or derivative thereof to ameliorate or eliminate the AUD, SUD, tobacco use, pain, or proinflammatory disorder, and wherein the modified tetracycline or derivative thereof has reduced binding to a microbial ribosome and has the formula wherein R1 is acetyl, R2 is OH or acetyl, R3 is acetyl, R4 is H or acetyl, and R5 is acetyl.
    Type: Grant
    Filed: June 13, 2019
    Date of Patent: January 3, 2023
    Assignee: Texas Tech University System
    Inventors: Susan E. Bergeson, Peter Syapin, Ted W. Reid, Mayank Shashtri, Phat Tran
  • Publication number: 20220404647
    Abstract: Disclosed is a system and method for solid-state 2D optical phased arrays (OPAs), which are fabricated from In-rich In1-xGaxN/GaN multiple quantum wells (MQWs). In-rich InxGa1-xN alloys possess the unique properties of exceptionally high free-carrier-induced refractive index (n) change and low optical loss. InGaN/GaN MQW pixels play the role of using a very small fraction of a laser beam to modulate the phase of the laser beam. The phase of each MQW pixel in the OPA is controlled independently via electro-optic effect through the integration between OPA pixels with a Laterally Diffused MOSFET (LDMOS) integrated circuit driver to achieve the manipulation of the distribution of optical power in the far field. The present invention is applicable to a wide range of applications, including the operation of LIDAR systems, laser weapons, laser illuminators, and laser imaging systems.
    Type: Application
    Filed: August 26, 2022
    Publication date: December 22, 2022
    Applicant: Texas Tech University System
    Inventors: Hongxing Jiang, Changzhi Li, Jing Li, Jingyu Lin
  • Patent number: 11510979
    Abstract: The present invention includes composition and methods for composition for the oral delivery of a therapeutic agent that reduces, desensitizes, or prevents food, respiratory and other allergies. First pollen is cleaned to remove naturally-occurring allergic plant proteins to form a cleaned pollen and a therapeutically effective amount of an allergen is introduced into the cleaned pollen. The allergen-loaded cleaned pollen is delivered to a subject in need of therapy.
    Type: Grant
    Filed: October 2, 2018
    Date of Patent: November 29, 2022
    Assignee: Texas Tech University System
    Inventors: Harvinder Singh Gill, Akhilesh Shakya
  • Publication number: 20220354823
    Abstract: Provided herein are maternal neonatal pheromonal agents capable of reducing aggression and improving feeding behavior in a pig. Compositions comprising the pheromonal agents and methods of using the agents to reduce aggression and improve feeding behavior and weight gain in the pig are also provided.
    Type: Application
    Filed: July 7, 2022
    Publication date: November 10, 2022
    Applicant: Texas Tech University System
    Inventor: John J. McGlone