Patents Assigned to The Curators of University of Missouri
  • Microsphere based patterning of metal optic/plasmonic sensors including fiber based sensors
    Patent number: 10989867
    Abstract: A fiber-based sensor and a method of forming a fiber-based sensor using microsphere lithography techniques in which a microsphere array is applied to a surface of a tip of an optical fiber to provide for microsphere lithography fabrication of a desired pattern on the tip of the optical fiber. The characteristics of the pattern define sensing capabilities of the sensor to provide for chemical and/or biological sensing.
    Type: Grant
    Filed: April 15, 2020
    Date of Patent: April 27, 2021
    Assignee: The Curators of the University of Missouri
    Inventors: Edward C. Kinzel, Mahmoud Almasri, Chuang Qu, Ibrahem Jasim, Jiayu Liu
  • Metal foils with ordered crystal structure and method for producing metal foils
    Patent number: 10980130
    Abstract: A method for producing a metal foil comprising depositing metal onto an oxidizable substrate to form a metal film on the substrate; oxidizing the substrate at an interface between the metal film and the substrate; and removing the metal film from the substrate to yield a metal foil. A method for forming a thin metal film comprising pre-polarizing a single-crystal Si substrate by application of a potential which is negative of a potential at which Si oxidizes, which pre-polarization occurs in the presence of metal ions to form metal growth nucleation sites on the substrate, followed by application of a potential at which both oxidation of Si and electrodeposition of the metal occur to grow the metal film and oxidize the Si to SiOx, which potential is more positive than the potential applied in the pre-polarization step.
    Type: Grant
    Filed: November 1, 2018
    Date of Patent: April 13, 2021
    Assignee: THE CURATORS OF THE UNIVERSITY OF MISSOURI
    Inventor: Jay A. Switzer
  • OXIDATION POLYMERIZATION ADDITIVE MANUFACTURING
    Publication number: 20210094226
    Abstract: Various processes for producing three dimensional electrically conductive polymer structures, such as three dimensional structures of poly(3,4-ethylenedioxythiophene), are described as well as materials produced by these processes.
    Type: Application
    Filed: September 28, 2020
    Publication date: April 1, 2021
    Applicant: The Curators of the University of Missouri
    Inventors: Jonghyun Park, Tazdik Patwary Plateau, Hiep Pham
  • Quantification of bulbar function
    Patent number: 10959661
    Abstract: System, method and media for quantifying bulbar function of a subject. At a high level, embodiments of the invention measure and quantify bulbar function of a test subject based on video data, audio data, or other sensor data of a subject performing a test of bulbar function, such as speech, swallowing, and orofacial movements. This sensor data is then analyzed to identify key events such as syllable enunciations. Based on one or more characteristics of these key events (such as, for example, their rate, count, assessed accuracy, or trends over time), the bulbar function of the subject can accurately, reliably, and objectively be quantified.
    Type: Grant
    Filed: April 5, 2018
    Date of Patent: March 30, 2021
    Assignee: The Curators of the University of Missouri
    Inventors: Teresa Lever, Filiz Bunyak Ersoy, Mili Kuruvilla-Dugdale, Yunxin Zhao
  • THERMAL LIQUID CONTAINER SYSTEM
    Publication number: 20210078789
    Abstract: A thermal liquid container system comprising a main body, a phase change material (PCM) liner disposed within the main body having a PCM disposed therein, a liquid reservoir defined by PCM liner, a liquid dispensing partition disposed within the liquid reservoir such that the liquid reservoir is partitioned into a temperature conditioning channel and a liquid retention chamber, and a lid comprising a liquid ingress and a liquid dispensing opening, the temperature conditioning channel for placing a liquid passing therethrough in thermal contact with the PCM whereby thermal energy is exchanged between the liquid flowing through the temperature conditioning channel and the PCM such that the liquid is dispensed at a temperature that is within a desired temperature range determined by the selected PCM melting temperature.
    Type: Application
    Filed: August 14, 2020
    Publication date: March 18, 2021
    Applicant: The Curators of the University of Missouri
    Inventor: Hongbin Ma
  • Radiolytic electrochemical generator
    Patent number: 10938045
    Abstract: A radiolytic electrochemical system that comprises a cathode, an anode that comprises a semiconductor, an aqueous electrolyte solution disposed between the cathode and anode, and ionizing radiation, wherein the ionizing radiation splits water molecules via radiolysis and forms solvated free radicals that migrate to the anode or cathode, depending upon a radical's charge, and participate in redox reactions at the anode and cathode thereby producing electrical current capable of performing work when the anode and cathode are electrically connected.
    Type: Grant
    Filed: December 20, 2019
    Date of Patent: March 2, 2021
    Assignee: The Curators of the University of Missouri
    Inventors: Jae Wan Kwon, Baek Hyun Kim
  • FUEL CELL HAVING CORRUGATED MEMBRANE ELECTRODE ASSEMBLY
    Publication number: 20210050612
    Abstract: An electrochemical reaction cell comprising an anode electrode, a cathode electrode, and a membrane electrode assembly (MEA). The MEA is positioned between the anode electrode and the cathode electrode. The anode electrode, the cathode electrode, and the MEA each have a corrugated shape and are contained within a recess of a housing.
    Type: Application
    Filed: August 14, 2020
    Publication date: February 18, 2021
    Applicant: The Curators of the University of Missouri
    Inventor: Jonghyun Park
  • Method for treating lymphedema
    Patent number: 10918629
    Abstract: The disclosure relates to the field of lymphedema therapy, more specifically, to a new pharmacological strategy to rescue the failed lymph pump system that can supplement, enhance or replace current therapies.
    Type: Grant
    Filed: October 20, 2015
    Date of Patent: February 16, 2021
    Assignee: The Curators of the University of Missouri
    Inventor: Michael John Davis
  • Method and system for secure resource management utilizing blockchain and smart contracts
    Patent number: 10924363
    Abstract: This disclosure relates to a resource management system of a computing network. The design of the resource management system is an edge-Internet of Things (IoT) framework based on blockchain and smart contracts. The resource management system integrates a permissioned blockchain to link the edge cloud resources with each account for an IoT device, resource usage, and behavior of the IoT device. The resource management system uses credit-based resource management to control the resource of the IoT device that can be obtained from the edge server. Smart contracts are used to regulate behavior of the IoT device and enforce policies.
    Type: Grant
    Filed: April 12, 2019
    Date of Patent: February 16, 2021
    Assignee: The Curators of the University of Missouri
    Inventors: Jianli Pan, Jianyu Wang
  • Microwave reflectometry for physical inspections
    Patent number: 10921264
    Abstract: Utilizing microwave reflections to compare a reference device with counterfeit and/or aging devices under test. The reflection from the device under test varies based on certain properties, which results in each device having a unique and intrinsic electromagnetic signature. Comparisons of the electromagnetic signature of the device under test to the electromagnetic signature of a reference device enable evaluating the acceptability of the device under test.
    Type: Grant
    Filed: August 18, 2017
    Date of Patent: February 16, 2021
    Assignee: THE CURATORS OF THE UNIVERSITY OF MISSOURI
    Inventors: Mohammad Tayeb Ghasr, Reza Zoughi, Satyajeet Shinde, Sasi Jothibasu
  • Method for scalable skeletal muscle lineage specification and cultivation
    Patent number: 10920196
    Abstract: The present disclosure relates to methods for enhancing cultured meat production, such as livestock-autonomous meat production. In certain aspects, the meat is any metazoan tissue or cell-derived comestible product intended for use as a comestible food or nutritional component by humans, companion animals, domesticated or captive animals whose carcasses are intended for comestible use, service animals, conserved animal species, animals used for experimental purposes, or cell cultures.
    Type: Grant
    Filed: April 20, 2016
    Date of Patent: February 16, 2021
    Assignees: The Curators of the University of Missouri, Memphis Meats, Inc.
    Inventors: Nicholas J. Genovese, R. Michael Roberts, Bhanu Prakash V. L. Telugu
  • AU multicomponent nanomaterials and synthesis methods
    Patent number: 10914734
    Abstract: Compositions which comprise a gold nanoparticle, dithiolated diethylenetriamine pentaacetic acid (DTDTPA), and a thioctic acid terminated peptide, wherein the DTDTPA is directly linked to the gold nanoparticle surface via an Au—S bond, and wherein the thioctic acid terminated peptide is directly linked to the gold nanoparticle surface via an Au—S bond.
    Type: Grant
    Filed: December 20, 2018
    Date of Patent: February 9, 2021
    Assignee: The Curators of the University of Missouri
    Inventors: Raghuraman Kannan, Ajit Zambre, Anandhi Upendran
  • Device and method for allografting
    Patent number: 10905437
    Abstract: In one embodiment, a cutting guide is disclosed for use in a surgical procedure to removed damaged tissue from a patient and form a recipient site configured and dimensioned to receive a donor graft. The cutting guide includes a first arm that abuts a section of the damaged tissue to be removed, and a second arm including a hole and a slot that receives a cutting implement, the first arm and the slot defining a distance therebetween corresponding to a desired dimension of the recipient site. In another embodiment, a cutting guide is disclosed for use in forming a donor graft from donor tissue. The cutting guide includes a body that receives the donor tissue, and a shaping member that is rotatably secured to the body. The shaping member includes at least one vane that shapes the donor tissue so as to form the donor graft.
    Type: Grant
    Filed: March 12, 2015
    Date of Patent: February 2, 2021
    Assignee: The Curators of the University of Missouri
    Inventors: Ferris M. Pfeiffer, James L. Cook, James P. Stannard
  • Cancer immune-based therapy
    Patent number: 10898563
    Abstract: The present disclosure provides a novel therapeutic vaccine approach that triggers a therapeutic antitumor response. The inventive approach is to selectively eliminate the carbohydrate sequences from tumor cells without affecting the tumor associated protein epitopes.
    Type: Grant
    Filed: February 28, 2017
    Date of Patent: January 26, 2021
    Assignee: The Curators of the University of Missouri
    Inventor: Gary Clark
  • MEDIUM SUPPLEMENT TO INCREASE THE EFFICIENCY OF OOCYTE MATURATION AND EMBRYO CULTURE IN VITRO
    Publication number: 20210017490
    Abstract: The present invention provides a novel oocyte maturation medium or/and embryo culture medium with a chemically defined supplement to produce matured oocytes at high efficiency. The inventive medium or supplement comprises three growth factors, namely, fibroblast growth factor 2 (FGF2), leukemia inhibitory factor (LIF), and insulin-like growth factor 1 (IGF-1) in a synergistic combination. Methods for oocyte and embryo culture are also provided.
    Type: Application
    Filed: June 3, 2020
    Publication date: January 21, 2021
    Applicant: The Curators of the University of Missouri
    Inventors: Ye Yuan, Lee D. Spate, Randall S. Prather, R. Michael Roberts
  • Tissue preservation system
    Patent number: 10881098
    Abstract: The present invention provides a method and apparatus for tissue, such as an allograft, storage and preservation for extended periods of time at room temperature in a sterile tissue culture chamber. The invention further provides a process for maintaining the sterility of tissue using the apparatus as described.
    Type: Grant
    Filed: June 28, 2018
    Date of Patent: January 5, 2021
    Assignees: The Curators of the University of Missouri, The Trustees of Columbia University in the City of New York
    Inventors: James L. Cook, Clark T. Hung, Eric Lima, Aaron Stoker
  • Increasing plant oil content by altering a negative regulator of acetyl-coa carboxylase
    Patent number: 10883113
    Abstract: The present invention provides a method and means to change fatty acid and ultimately triacylglycerol production in plants and algae. Methods of the invention comprise the step of altering the activity levels of the committed step for de novo fatty acid biosynthesis, acetyl-CoA carboxylases (ACCase). More specifically, methods of the invention directly enhance the activity of ACCase by down-regulating the biotin/lipoyl attachment domain containing (BADC) genes through biotechnology or selective breeding approaches.
    Type: Grant
    Filed: July 7, 2016
    Date of Patent: January 5, 2021
    Assignee: The Curators of The University of Missouri
    Inventors: Jay Thelen, Matthew Salie
  • THREE-PHASE OSCILLATING HEAT PIPE
    Publication number: 20200400380
    Abstract: The present disclosure generally provides an oscillating heat pipe, wherein the oscillating heat pipe comprises a 3-phase working fluid that includes at least one liquid phase portion, at least one vapor phase portion, and at least one solid phase portion, wherein in addition to a phase change between liquid and vapor, there is also a phase change from solid to liquid during a heat transfer process involving the oscillating heat pipe.
    Type: Application
    Filed: June 18, 2020
    Publication date: December 24, 2020
    Applicant: The Curators of the University of Missouri
    Inventors: Hongbin Ma, Michael Merwin, Adalberto Aviles, Tingting Hao
  • PHOTONUCLEAR TRANSMUTATION DOPING IN GALLIUM-BASED SEMICONDUCTOR MATERIALS
    Publication number: 20200402802
    Abstract: The present invention relates to various high quality n-type and p-type doped gallium-based semiconductor materials, electronic components incorporating these materials, and processes of producing these materials. In particular, The present invention relates processes to achieve high quality, uniform doping of a whole wafer or a thin layer of gallium-based semiconductor materials for various applications such as a vertical power transistor or diode.
    Type: Application
    Filed: June 18, 2020
    Publication date: December 24, 2020
    Applicant: The Curators of the University of Missouri
    Inventors: Jae Wan Kwon, Quang Nguyen
  • METAL-CERAMIC COMPOSITE POWDERS
    Publication number: 20200391294
    Abstract: A process for manufacturing metal-ceramic composite material powder comprising ball milling metal powder and ceramic nanoparticles to yield a metal-ceramic composite powder comprising ceramic nanoparticles embedded in a metal matrix powder particles; wherein the ball milling is performed using a ceramic milling media and a milling vessel having a ceramic interior surface. Metal matrix nanocomposite powders comprising ceramic nanoparticles imbedded in metal matrix powder particles; wherein the metal matrix powder particles have a spherical shape; wherein there is uniform distribution the ceramic nanoparticles; wherein the nanocomposite powders have good flowability.
    Type: Application
    Filed: June 15, 2020
    Publication date: December 17, 2020
    Applicant: The Curators of the University of Missouri
    Inventors: Lianyl Chen, Minglei Qu