Patents Assigned to The Doshisha
  • Publication number: 20230197973
    Abstract: In a case where an alkali aqueous solution is used as an electrolyte, provided are an oxygen catalyst excellent in catalytic activity and composition stability, an electrode having high activity and stability using this oxygen catalyst, and an electrochemical measurement method that can evaluate the catalytic activity of the oxygen catalyst alone. The oxygen catalyst is an oxide having peaks at positions of 2?=30.07°±1.00°, 34.88°±1.00°, 50.20°±1.00°, and 59.65°±1.00° in an X-ray diffraction measurement using a CuK? ray, and having constituent elements of bismuth, ruthenium, sodium, and oxygen. An atom ratio O/Bi of oxygen to bismuth and an atom ratio O/Ru of oxygen to ruthenium are both more than 3.5.
    Type: Application
    Filed: May 19, 2021
    Publication date: June 22, 2023
    Applicant: THE DOSHISHA
    Inventor: Masatsugu MORIMITSU
  • Patent number: 11652204
    Abstract: Provided is a metal negative electrode used for a secondary battery. The metal negative electrode includes an active material portion, a current collector, and a non-electronically conductive reaction space divider. The active material portion forms metal during charging and forms an oxidation product of the metal during discharging. The metal is used as a negative-electrode active material. The current collector is electrically connected to the active material portion. The non-electronically conductive reaction space divider is integrally formed with or connected to the current collector and/or the active material portion. The reaction space divider has a plurality of electrolyte holder portions configured to hold a liquid electrolyte.
    Type: Grant
    Filed: September 11, 2020
    Date of Patent: May 16, 2023
    Assignees: THE DOSHISHA, DOWA HOLDINGS Co., Ltd.
    Inventor: Masatsugu Morimitsu
  • Patent number: 11633477
    Abstract: The present invention provides a technique for treating the cornea. More specifically, the present invention is an agent for the treatment or prevention of a state of corneal endothelial disease, the agent including at least one factor selected from the group consisting of laminin and fragments thereof, wherein the problem is solved by also providing a technique characterized in that this agent is administered together with corneal endothelial cells. Specifically, the present invention can include laminin 511 (?5?1?1), laminin 521 (?5?2?1), or a fragment of these.
    Type: Grant
    Filed: October 30, 2015
    Date of Patent: April 25, 2023
    Assignees: KYOTO PREFECTURAL PUBLIC UNIVERSITY CORPORATION, THE DOSHISHA, SENJU PHARMACEUTICAL CO., LTD.
    Inventors: Noriko Koizumi, Naoki Okumura, Shigeru Kinoshita
  • Patent number: 11627485
    Abstract: A computer system includes at least one memory and at least one processor coupled to the at least one memory and configured to execute one or more sets of instructions. The one or more sets of instructions, when executed by the at least one processor, cause the computer system to provide virtualized radio access network functions including executing a BP algorithm and provide controller functions including adjusting the total number of iterations of the BP algorithm depending on available computing resources of the computer system.
    Type: Grant
    Filed: April 14, 2021
    Date of Patent: April 11, 2023
    Assignees: NEC CORPORATION, OSAKA UNIVERSITY, THE DOSHISHA
    Inventors: Kazushi Muraoka, Naoto Ishii, Takumi Takahashi, Shinsuke Ibi
  • Publication number: 20230086958
    Abstract: There are provided a method for predicting a springback amount and a method for bending a deformed reinforcing bar including: supplying the deformed reinforcing bar bending the supplied deformed reinforcing bar, and subsequently measuring a first bending angle in a state of releasing a bending force on the deformed reinforcing bar; further bending the reinforcing bar from which the bending force has been released, and subsequently measuring a second bending angle in a state of releasing the bending force; and predicting a relationship between the bending angle and the springback amount by using the measurement results after executing the further bending once or a plurality of times, in which the bending angle is greater for subsequent steps.
    Type: Application
    Filed: September 13, 2022
    Publication date: March 23, 2023
    Applicants: THE DOSHISHA, TOYO KENSETSU KOHKI CO., LTD.
    Inventors: Masahiro SASADA, Ikuho MATSUKUMA, Satoshi HIGAKI
  • Publication number: 20230075680
    Abstract: A wireless receiving apparatus generates an N?×B? weight matrix W whose columns are orthogonal to each other by decomposing an estimated N?×M? channel matrix into the N?×B? weight matrix W and a B?×M? matrix containing two or more non-zero matrix elements in each column, where B? is an integer less than or equal to N?-1 and greater than or equal to M?. Alternatively, the wireless receiving apparatus generates a combination of an N?×B? sub-weight matrix W1 and at least one second sub-weight matrix, where the product of the sub-weight matrix W1 with the at least one second sub-weight matrix is equal to the weight matrix W. The wireless receiving apparatus performs receive beamforming on received signals of N? receiving antennas using the weight matrix W or the sub-weight matrix W1. The wireless receiving apparatus then performs a BP algorithm using receive-beamformed signals.
    Type: Application
    Filed: August 30, 2022
    Publication date: March 9, 2023
    Applicants: NEC CORPORATION, OSAKA UNIVERSITY, THE DOSHISHA
    Inventors: Takanobu DOI, Kazushi MURAOKA, Naoto ISHII, Takumi TAKAHASHI, Shinsuke IBI
  • Patent number: 11595153
    Abstract: A method implemented in a computer system includes training a network, which is obtained by unfolding an iterative algorithm for demodulation or demodulation and decoding, using a machine learning technique with a loss function that takes into account non-Gaussianity of a log-likelihood ratio (LLR) distribution calculated from an output of the network. The method further includes producing a first set of learned parameters of that iterative algorithm.
    Type: Grant
    Filed: February 16, 2022
    Date of Patent: February 28, 2023
    Assignees: NEC CORPORATION, OSAKA UNIVERSITY, THE DOSHISHA
    Inventors: Kazushi Muraoka, Takanobu Doi, Naoto Ishii, Takumi Takahashi, Seiichi Sampei, Shinsuke Ibi
  • Patent number: 11576914
    Abstract: Provided is a medicament or a method for treating or preventing a corneal endothelial condition, disorder or disease due to a transforming growth factor-? (TGF-?) signal in corneal endothelial cells using a p38 MAP kinase inhibitor (in particular AKP-001), such as a pyrimidinyl isoxazole derivative or a pyridyl isoxazole derivative. In a preferred embodiment, the corneal endothelial condition, disorder or disease due to the TGF-? signal is Fuchs' corneal endothelial dystrophy.
    Type: Grant
    Filed: July 25, 2018
    Date of Patent: February 14, 2023
    Assignee: THE DOSHISHA
    Inventors: Noriko Koizumi, Naoki Okumura
  • Publication number: 20220370977
    Abstract: The present disclosure provides a method for forming a liquid flow in a surface region of a liquid, and a method for moving a larger object in a non-contact and non-invasive manner.
    Type: Application
    Filed: September 15, 2020
    Publication date: November 24, 2022
    Applicant: The Doshisha
    Inventors: Takahiro Kenmotsu, Kenichi Yoshikawa, Satoshi Takatori, Mayu Shono
  • Patent number: 11492485
    Abstract: There are provided a resin composition that is suitable for the production of a flame-retardant molded article and that can provide high flame retardancy even with a small amount of flame retardant added, and a flame retardancy determination method for determining the flame retardancy of a resin composition. The resin composition of the present invention contains a thermoplastic resin, a cellulosic material, and a phosphate flame retardant and satisfies relational expressions (1) and (2) (where in expressions (1) and (2), TP, TB, and TCMP are temperatures at weight loss rate peaks in thermogravimetric analysis, TP is a temperature (° C.) at a weight loss rate peak of the thermoplastic resin, TB is a temperature (° C.) at a weight loss rate peak of the cellulosic material, and TCMP is a temperature (° C.) at a weight loss rate peak of the resin composition. When the resin composition has two weight loss rate peaks, TCMP is a temperature at a peak on a lower temperature side).
    Type: Grant
    Filed: March 26, 2018
    Date of Patent: November 8, 2022
    Assignee: THE DOSHISHA
    Inventors: Tatsuya Tanaka, Yukinori Sano, Kenta Masuyama
  • Publication number: 20220337341
    Abstract: A method implemented in a computer system includes training a network, which is obtained by unfolding an iterative algorithm for demodulation or demodulation and decoding, using a machine learning technique with a loss function that takes into account non-Gaussianity of a log-likelihood ratio (LLR) distribution calculated from an output of the network. The method further includes producing a first set of learned parameters of that iterative algorithm.
    Type: Application
    Filed: February 16, 2022
    Publication date: October 20, 2022
    Applicants: NEC CORPORATION, OSAKA UNIVERSITY, THE DOSHISHA
    Inventors: Kazushi MURAOKA, Takanobu Doi, Naoto Ishii, Takumi Takahashi, Seiichi Sampei, Shinsuke Ibi
  • Publication number: 20220320488
    Abstract: Provided is a metal negative electrode that has an excellent repeat resistance and is excellent in charge and discharge cycle characteristics even in a high charge and discharge rate, a method for fabricating the same, and a secondary battery using the metal negative electrode. The metal negative electrode is a metal negative electrode used for a secondary battery, which includes an active material portion, a current collector, and a non-electronically conductive reaction space divider. The active material portion forms metal during charging and forms an oxidation product of the metal during discharging. The metal is used as a negative-electrode active material. The current collector is electrically connected to the active material portion. The non-electronically conductive reaction space divider is integrally formed with or connected to the current collector and/or the active material portion. The reaction space divider has a plurality of electrolyte holder portions configured to hold a liquid electrolyte.
    Type: Application
    Filed: September 11, 2020
    Publication date: October 6, 2022
    Applicants: THE DOSHISHA, DOWA HOLDINGS Co., Ltd.
    Inventor: Masatsugu MORIMITSU
  • Publication number: 20220296580
    Abstract: The present invention provides a treatment drug or prophylactic drug for diseases, disorders, or conditions related to endoplasmic reticulum (ER) stress. Specifically, the present invention provides a treatment drug or prophylactic drug for diseases, disorders, or conditions related to endoplasmic reticulum (ER) stress in the corneal epithelium, the drug containing a TGF?-signal inhibitor. As a preferred TGF?-signal inhibitor, the drug contains 4-[4-(1,3-benzodioxole-5-yl)-5-(2-pyridinyl)-1H-imidazole-2-yl]benzamide.
    Type: Application
    Filed: June 3, 2022
    Publication date: September 22, 2022
    Applicants: Kyoto Prefectural Public University Corporation, The Doshisha, Senju Pharmaceutical Co., Ltd.
    Inventors: Noriko KOIZUMI, Naoki OKUMURA, Shigeru KINOSHITA
  • Patent number: 11450888
    Abstract: One aspect of the present invention is a nonaqueous electrolyte for an energy storage device comprising: an alkali metal salt; a first aprotic organic solvent coordinating to an alkali metal ion in the alkali metal salt, and not including a fluorine atom; a second aprotic organic solvent including a fluorine atom; and an additive comprising a polar group and a group including a fluorine atom, wherein a content of the alkali metal salt is no less than 0.9 mol/kg and less than 2 mol/kg, a content of the first aprotic organic solvent with respect to the content of the alkali metal salt in terms of a molar ratio is no less than 0.7 and no greater than 4, and a content of the second aprotic organic solvent with respect to a total amount of the first aprotic organic solvent, the second aprotic organic solvent and the additive is no less than 40% by volume.
    Type: Grant
    Filed: August 10, 2018
    Date of Patent: September 20, 2022
    Assignees: GS Yuasa International Ltd., THE DOSHISHA
    Inventors: Hiroe Nakagawa, Katsuyuki Takahashi, Minoru Inaba, Takayuki Doi, Ryo Matsumoto
  • Patent number: 11445723
    Abstract: The present disclosure provides a method of preserving corneal endothelial cells at a high cell survival rate. The present disclosure provides a method of preserving corneal endothelial cells and/or corneal endothelium-like cells, comprising preserving the corneal endothelial cells and corneal endothelium-like cells in a container with a bottom area of at least about 0.7 cm2. Accordingly to the present invention, corneal endothelial cells can be preserved at a high cell survival rate. Corneal endothelial cells preserved in this manner have functions of normal corneal endothelial cells. Such cells can also be used as cells for treating a corneal endothelial disease or the like.
    Type: Grant
    Filed: October 2, 2019
    Date of Patent: September 20, 2022
    Assignee: The Doshisha
    Inventors: Noriko Koizumi, Naoki Okumura
  • Patent number: 11446263
    Abstract: Provided is a drug or method for treating or preventing a condition, disorder, or disease of the corneal endothelium caused by transforming growth factor-? (TGF-?) signals and/or mitochondrial abnormalities in corneal endothelial cells. The present invention provides a drug which includes caspase inhibitors, and which is for treating or preventing a condition, disorder, or disease of the corneal endothelium caused by TGF-? signals and/or mitochondrial abnormalities in corneal endothelial cells. In the preferred embodiment, the condition, disorder, or disease of the corneal endothelium is Fuchs' corneal endothelial dystrophy.
    Type: Grant
    Filed: December 22, 2016
    Date of Patent: September 20, 2022
    Assignee: The Doshisha
    Inventors: Noriko Koizumi, Naoki Okumura
  • Patent number: 11433090
    Abstract: The present invention provides a medicine and a method for preventing or treating ophthalmic symptoms, disorders, or diseases. The present invention provides an mTOR-inhibitor-containing composition for preventing or treating ophthalmic symptoms, disorders, or diseases. In some of the embodiments of the present invention, this composition is capable of treating or preventing corneal endothelial symptoms, disorders, or diseases; in particular, corneal endothelial symptoms, disorders, or diseases that are attributed to overexpression of the transforming growth factor-? (TGF-?) signal and/or extracellular matrix (ECM).
    Type: Grant
    Filed: June 15, 2018
    Date of Patent: September 6, 2022
    Assignee: The Doshisha
    Inventors: Noriko Koizumi, Naoki Okumura
  • Patent number: 11382904
    Abstract: The present invention provides a treatment drug or prophylactic drug for diseases, disorders, or conditions related to endoplasmic reticulum (ER) stress. Specifically, the present invention provides a treatment drug or prophylactic drug for diseases, disorders, or conditions related to endoplasmic reticulum (ER) stress in the corneal epithelium, the drug containing a TGF?-signal inhibitor. As a preferred TGF?-signal inhibitor, the drug contains 4-[4-(1,3-benzodioxole-5-yl)-5-(2-pyridinyl)-1H-imidazole-2-yl]benzamide.
    Type: Grant
    Filed: October 30, 2014
    Date of Patent: July 12, 2022
    Assignees: Kyoto Prefectural Public University Corporation, The Doshisha, Senju Pharmaceutical Co., Ltd.
    Inventors: Noriko Koizumi, Naoki Okumura, Shigeru Kinoshita
  • Patent number: 11309991
    Abstract: A BP detector of a wireless receiver apparatus reads a first parameter set or a second parameter set. The first parameter set includes a plurality of scaling factors and a plurality of damping factors learned together using a deep learning technique. The second parameter set includes a plurality of scaling factors and a plurality of node selection factors learned together using a deep learning technique from a memory. The BP detector executes an iterative BP algorithm that uses the first parameter set or the second parameter set in order to perform multi-user detection.
    Type: Grant
    Filed: April 14, 2021
    Date of Patent: April 19, 2022
    Assignees: NEC CORPORATION, OSAKA UNIVERSITY, THE DOSHISHA
    Inventors: Kazushi Muraoka, Naoto Ishii, Takumi Takahashi, Seiichi Sampei, Shinsuke Ibi
  • Patent number: 11295939
    Abstract: An analytical device includes: a reaction unit into which an ion derived from a sample component is introduced; a radical generation unit that generates a radical by vacuum discharge and comprises a raw material introduction chamber into which a plasma raw material is introduced; a connection part that introduces the radical generated in the radical generation unit into a vacuum chamber, the vacuum chamber having a pressure lower than a pressure of the raw material introduction chamber and being connected to the reaction unit; and a separation unit that separates a generated ion generated by a reaction with the radical introduced via the connection part into the reaction unit according to m/z and/or ion mobility, wherein an inner diameter of a cross section of the connection part is equal to or less than 20 millimeters.
    Type: Grant
    Filed: April 25, 2019
    Date of Patent: April 5, 2022
    Assignees: SHIMADZU CORPORATION, THE DOSHISHA
    Inventors: Hidenori Takahashi, Motoi Wada, Yuji Shimabukuro