Patents Assigned to The Hong Kong Polytechnic University
  • Patent number: 12037361
    Abstract: The present disclosure provides methods and composition for treating multi-drug resistant cancers, in particular, breast cancers, via administration to a subject the composition including a peptide having a sequence complementary to a highly conserved motif present in substantially all integrins responsible for an integrin-mediated attachment-independent chemoresistance to one or more chemotherapeutic agents. The binding of the sequence of the peptide to the highly conserved motif will enhance accumulation of the chemotherapeutic agents in the tumor-initiating cells and in turn restores the function of the chemotherapeutic agents in the tumor-initiating cells.
    Type: Grant
    Filed: August 31, 2022
    Date of Patent: July 16, 2024
    Assignee: THE HONG KONG POLYTECHNIC UNIVERSITY
    Inventors: Ming-Cheung Larry Chow, Kit Ying Choy, Chin Fung Chan, Lai King Wong
  • Patent number: 12031754
    Abstract: A smart sub-ambient radiative cooling composition including TiO2 particles; inorganic particles selected from the group consisting of SiO2, CaCO3, SiC, ZnO, Al2O3, ZnO, and mixtures thereof; fluorescent pigment particles; and a polymer useful for sub-ambient radiative cooling, methods of preparation, and use thereof.
    Type: Grant
    Filed: October 29, 2020
    Date of Patent: July 9, 2024
    Assignee: THE HONG KONG POLYTECHNIC UNIVERSITY
    Inventors: Jianguo Dai, Xiao Xue, Dangyuan Lei, Meng Qiu, Wei Jin
  • Publication number: 20240210837
    Abstract: An algorithm-driven digital ultraviolet (UV) lithography (DUL) method and apparatus used to fabricate high-quality optical waveguide and many other kinds of high-resolution microstructures without the use of a photomask. Instead of the use of an actual photomask, a virtual mask based on a spatial light modulator is used. The DUL method and apparatus can compensate for a proximity effect caused by light scattering and make the exposure adaptive to a nonlinear response curve of a photoresist, in which an exposure dose-map is created based on the bitmap of a designed pattern together with the optimization parameters determined by system configuration and the photoresist. To fabricate large-area patterns, a plurality of sliced exposure dose-submaps with transition zones that can depress the stitching error caused by mechanical mispositioning are generated for digital lithographic exposure process.
    Type: Application
    Filed: December 22, 2022
    Publication date: June 27, 2024
    Applicant: The Hong Kong Polytechnic University
    Inventors: Aping ZHANG, Zuoqin DING, Han WANG, Taige LI
  • Patent number: 12019312
    Abstract: A spectacle lens can inhibit ametropia of the eyes and ensure full visibility. The spectacle lens comprises: first refraction areas and second refraction areas. Each first refraction area has a first refraction force that may be based on a prescription for correcting the ametropia of the eyes. Each second refraction area has a refraction force different from the first refraction force and may function to focus images on the positions except the retina of the eyes, to inhibit the development of the ametropia. Near the central part of the lens, the second refraction areas form a plurality of independent island-shaped areas, and the first refraction areas form the areas beyond the areas of the second refraction areas.
    Type: Grant
    Filed: June 29, 2023
    Date of Patent: June 25, 2024
    Assignees: HOYA LENS THAILAND LTD., THE HONG KONG POLYTECHNIC UNIVERSITY
    Inventors: Chi Ho To, Siu Yin Lam, Takashi Hatanaka, Yasutake Masuda
  • Patent number: 11946523
    Abstract: A wideband vibration suppression device utilizing properties of a sonic black hole, comprising: a vibration absorber (101) comprising a uniform portion (1011) of a fixed thickness and a conical portion (1012) integrally connected to the uniform portion (1011), the conical portion (1012) extending from the junction in such a manner that the thickness thereof gradually decreases from the thickness (d1) of the uniform portion (1011) to a predetermined thickness (d2); and a damping layer (102) attached to the conical portion (1012) of the vibration absorber (101).
    Type: Grant
    Filed: October 17, 2018
    Date of Patent: April 2, 2024
    Assignee: THE HONG KONG POLYTECHNIC UNIVERSITY
    Inventors: Li Cheng, Tong Zhou
  • Patent number: 11949464
    Abstract: The present application relates to a dual-polarization-joint noise processing method and device. The present application compensates the discrete spectral coefficient noise on the X polarization state with noise information carried by the discrete spectral eigenvalue on the X, Y polarization states, and a correlation coefficient between the discrete spectral eigenvalue and the discrete spectral coefficient on the X polarization state. Similarly, compensating the discrete spectral coefficient noise on the Y polarization state with noise information carried by the discrete spectral eigenvalue on the X, Y polarization states, and a correlation coefficient between the discrete spectral eigenvalue and the discrete spectral coefficient on the Y polarization state.
    Type: Grant
    Filed: December 5, 2022
    Date of Patent: April 2, 2024
    Assignee: Shenzhen Research Institute of the Hong Kong Polytechnic University
    Inventors: Chuang Xu, Pak Tao Lau
  • Patent number: 11939704
    Abstract: A woven, water-vapor permeable, water-responsive, shape-memory wool fabric that possesses switchable pore size and shape responsive to varying water content absorbed thereby is demonstrated, more particularly, the wool fabric exerts corresponding thermal and water vapor regulations between the wearer and the surroundings with respect to the temperature and humidity changes.
    Type: Grant
    Filed: October 18, 2021
    Date of Patent: March 26, 2024
    Assignees: City University of Hong Kong, The Hong Kong Polytechnic University
    Inventors: Jinlian Hu, Mohammad Irfan Iqbal
  • Patent number: 11931282
    Abstract: The present disclosure provides a bracewear for spinal correction and a system for posture training. The system for posture training involves both active and passive corrective forces by using the bracewear and a biofeedback system to address the spinal correction, which can eliminate the adversity of conventional hard braces and reduce the psychological and physiological barriers to treatment.
    Type: Grant
    Filed: October 15, 2020
    Date of Patent: March 19, 2024
    Assignee: The Hong Kong Polytechnic University
    Inventors: Yiu-Wan Joanne Yip, Yin Ling Sit, Ting Hin Mak, Kit Lun Yick, Tsz Hei Cheung, Sui Pui Ng, Kenny Yat Hong Kwan, Mei Chun Cheung, Ming Fai Chan
  • Publication number: 20240088412
    Abstract: Embodiments of the present disclosure provide a fuel cell power generation device, which includes: a fuel cell with an anode and a cathode, for decomposing hydrogen and generating electric energy through reaction of decomposed hydrogen and oxygen; a first delivery pipe connected between a pipeline of a hydrogen-containing gas and the fuel cell, for delivering the hydrogen-containing gas to the anode of the fuel cell; a first output pipe connected to the fuel cell, for discharging a first remaining gas contacted with the anode of the fuel cell; a second delivery pipe connected to the fuel cell, for delivering an oxygen-containing gas to the cathode of the fuel cell; and a second output pipe connected to the fuel cell, for discharging a second remaining gas contacted with the cathode of the fuel cell.
    Type: Application
    Filed: August 4, 2023
    Publication date: March 14, 2024
    Applicants: The Hong Kong Polytechnic University, Yee Hop Environmental Protection Limited
    Inventors: Ka Wai Eric Cheng, Yuk Ping Cho
  • Patent number: 11905607
    Abstract: The present disclosure provides a pure-H2O-fed membrane-electrode assembly (MEA) electrolysis system for electrocatalytic CO2 reduction (ECO2R) to ethylene (C2H4) and C2+ compounds under an industrial applicable continuous flow condition with at least 1000-hour lifetime, and fabrication method thereof.
    Type: Grant
    Filed: June 9, 2022
    Date of Patent: February 20, 2024
    Assignee: THE HONG KONG POLYTECHNIC UNIVERSITY
    Inventors: Xiaojie She, Shu-Ping Lau
  • Patent number: 11885039
    Abstract: Methods for preparing a monolayer or few-layer centimeter-scale crystalline black phosphorus film, products thereof, and electronic and optoelectronic devices including the same.
    Type: Grant
    Filed: May 5, 2022
    Date of Patent: January 30, 2024
    Assignee: THE HONG KONG POLYTECHNIC UNIVERSITY
    Inventors: Jianhua Hao, Zehan Wu
  • Patent number: 11860043
    Abstract: In an indoor environment on fire, automatic deployment of sensors disposed on, beneath or over the floor to look upward the ceiling to observe a body of smoke and flame risen near the ceiling allows important information regarding states and dynamics of the body of smoke and flame to be gathered at an early stage of fire (e.g. before arrival of firefighters). By distributing the sensors over the indoor environment, the states and dynamics of the body of smoke and flame are monitored holistically (i.e. as a whole) even at the early stage of fire. Such information is useful to predict development of the fire. In one implementation, a sensor is held in an infrastructure sensor holder mounted on the ceiling during normal time. Upon detecting occurrence of fire, the sensor drops from the holder to land on the floor and orients a sensing direction vertically upward to perform monitoring.
    Type: Grant
    Filed: August 24, 2021
    Date of Patent: January 2, 2024
    Assignee: THE HONG KONG POLYTECHNIC UNIVERSITY
    Inventors: Qixin Wang, Xinyan Huang, Muhammad Shaheer, Tamzid Mohammad, Xiaoning Zhang, Mingchun Luo, Li-Ta Hsu, Xiqiang Wu, Fu Xiao, Asif Usmani
  • Patent number: 11826341
    Abstract: A method of treating an ocular nerve injury in a subject in need thereof, the method comprising administering a therapeutically effective amount of baicalein or an analog thereof.
    Type: Grant
    Filed: February 9, 2022
    Date of Patent: November 28, 2023
    Assignees: THE HONG KONG POLYTECHNIC UNIVERSITY
    Inventors: Chi Wai Do, Chi ho To, Li Pan, Dongfeng Chen, Kin-Sang Cho
  • Publication number: 20230341708
    Abstract: A spectacle lens can inhibit ametropia of the eyes and ensure full visibility. The spectacle lens comprises: first refraction areas and second refraction areas. Each first refraction area has a first refraction force that may be based on a prescription for correcting the ametropia of the eyes. Each second refraction area has a refraction force different from the first refraction force and may function to focus images on the positions except the retina of the eyes, to inhibit the development of the ametropia. Near the central part of the lens, the second refraction areas form a plurality of independent island-shaped areas, and the first refraction areas form the areas beyond the areas of the second refraction areas.
    Type: Application
    Filed: June 29, 2023
    Publication date: October 26, 2023
    Applicants: HOYA LENS THAILAND LTD., THE HONG KONG POLYTECHNIC UNIVERSITY
    Inventors: Chi Ho TO, Siu Yin LAM, Takashi HATANAKA, Yasutake MASUDA
  • Patent number: 11768288
    Abstract: A transparent ultrasound transducer device for multi-mode optical imaging on a target is provided. The device includes a transparent piezoelectric transducer, one or more wires, and an optical lens. The transparent piezoelectric transducer of a first acoustic impedance is configured to receive acoustic waves from the target. The transparent piezoelectric transducer has a first surface and a second surface. The first surface and the second surface are coated with transparent electrically conductive coatings. The optical lens is contacted with and optically coupled to the first surface of the transparent piezoelectric transducer. The optical lens is made of a material with a second acoustic impedance, and the first and second acoustic impedances are substantially similar to minimize an acoustic impedance mismatch such that sensitivity of the device is improved.
    Type: Grant
    Filed: March 20, 2023
    Date of Patent: September 26, 2023
    Assignee: THE HONG KONG POLYTECHNIC UNIVERSITY
    Inventors: Kwok Ho Lam, Riqiang Lin, Dongliang Shi
  • Publication number: 20230295445
    Abstract: A method of preparing antimicrobial 3D-printed material with antimicrobial agents integrated with the 3D-printed material. The 3D-printed material fabricated with the method of the present disclosure includes antimicrobial agent (s) fully integrated throughout the product and display antimicrobial effect throughout the product, which is resistant to daily wear and tear.
    Type: Application
    Filed: September 23, 2020
    Publication date: September 21, 2023
    Applicant: The Hong Kong Polytechnic University
    Inventors: Kwan Yu Lo, Chi Wai Kan
  • Publication number: 20230273458
    Abstract: A technology for inhibition of myopia progression adapted to the RPR of the wearer is provided. A spectacle lens and related technology are provided that include a base area that causes a beam that enters through an object-side surface to exit through an eye-side surface and converge on a retina via the eye, and a plurality of defocus areas that each contact the base area and have a characteristic whereby a beam that passes through at least a portion of the defocus area is incident on the retina as a diverging ray, and, in not less than half of the plurality of defocus areas, at least one of a defocus power and a size of each defocus area is set, so as to compensate for a change in retinal spot size due to relative peripheral refraction (RPR) that depends on an eccentricity angle of the eye of the wearer.
    Type: Application
    Filed: July 14, 2021
    Publication date: August 31, 2023
    Applicants: HOYA LENS THAILAND LTD., THE HONG KONG POLYTECHNIC UNIVERSITY
    Inventors: Hua QI, Chi Ho TO, Siu Yin LAM
  • Patent number: 11732403
    Abstract: Provided herein are methods for preparing metal coated textile substrate by ultrasonic irradiation deposition processes and products thereof.
    Type: Grant
    Filed: September 18, 2019
    Date of Patent: August 22, 2023
    Assignee: THE HONG KONG POLYTECHNIC UNIVERSITY
    Inventors: Nuruzzaman Noor, Suhas Mutalik
  • Patent number: 11726348
    Abstract: A spectacle lens can inhibit ametropia of the eyes and ensure full visibility. The spectacle lens comprises: first refraction areas and second refraction areas. Each first refraction area has a first refraction force that may be based on a prescription for correcting the ametropia of the eyes. Each second refraction area has a refraction force different from the first refraction force and may function to focus images on the positions except the retina of the eyes, to inhibit the development of the ametropia. Near the central part of the lens, the second refraction areas form a plurality of independent island-shaped areas, and the first refraction areas form the areas beyond the areas of the second refraction areas.
    Type: Grant
    Filed: June 21, 2022
    Date of Patent: August 15, 2023
    Assignees: THE HONG KONG POLYTECHNIC UNIVERSITY, HOYA LENS THAILAND LTD.
    Inventors: Chi Ho To, Siu Yin Lam, Takashi Hatanaka, Yasutake Masuda
  • Patent number: 11633620
    Abstract: A method for optogenetics experiments, based on wavefront shaping and including: calculating the transmission matrix between an input end and an output end of the multimode fiber under a fixed shape; implanting the output end into an intracranial space of an experimental subject; and performing wavefront compensation to a light to be input into the input end, according to the spatial position of the optical stimulation and the transmission matrix of the multimode fiber, to form a compensated expanded light, and inputting the compensated expanded light from the input end into the multimode fiber, such that the compensated expanded light, after being transmitted by the multimode fiber to the output end and output from the output end, is capable of focusing at the spatial position of the optical stimulation.
    Type: Grant
    Filed: April 8, 2020
    Date of Patent: April 25, 2023
    Assignee: THE HONG KONG POLYTECHNIC UNIVERSITY SHENZHEN RESEARCH INSTITUTE
    Inventors: Puxiang Lai, Lei Sun, Tianting Zhong, Zhihai Qiu