Patents Assigned to The Hong Kong Polytechnic University
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Patent number: 12037361Abstract: The present disclosure provides methods and composition for treating multi-drug resistant cancers, in particular, breast cancers, via administration to a subject the composition including a peptide having a sequence complementary to a highly conserved motif present in substantially all integrins responsible for an integrin-mediated attachment-independent chemoresistance to one or more chemotherapeutic agents. The binding of the sequence of the peptide to the highly conserved motif will enhance accumulation of the chemotherapeutic agents in the tumor-initiating cells and in turn restores the function of the chemotherapeutic agents in the tumor-initiating cells.Type: GrantFiled: August 31, 2022Date of Patent: July 16, 2024Assignee: THE HONG KONG POLYTECHNIC UNIVERSITYInventors: Ming-Cheung Larry Chow, Kit Ying Choy, Chin Fung Chan, Lai King Wong
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Patent number: 12031754Abstract: A smart sub-ambient radiative cooling composition including TiO2 particles; inorganic particles selected from the group consisting of SiO2, CaCO3, SiC, ZnO, Al2O3, ZnO, and mixtures thereof; fluorescent pigment particles; and a polymer useful for sub-ambient radiative cooling, methods of preparation, and use thereof.Type: GrantFiled: October 29, 2020Date of Patent: July 9, 2024Assignee: THE HONG KONG POLYTECHNIC UNIVERSITYInventors: Jianguo Dai, Xiao Xue, Dangyuan Lei, Meng Qiu, Wei Jin
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Publication number: 20240210837Abstract: An algorithm-driven digital ultraviolet (UV) lithography (DUL) method and apparatus used to fabricate high-quality optical waveguide and many other kinds of high-resolution microstructures without the use of a photomask. Instead of the use of an actual photomask, a virtual mask based on a spatial light modulator is used. The DUL method and apparatus can compensate for a proximity effect caused by light scattering and make the exposure adaptive to a nonlinear response curve of a photoresist, in which an exposure dose-map is created based on the bitmap of a designed pattern together with the optimization parameters determined by system configuration and the photoresist. To fabricate large-area patterns, a plurality of sliced exposure dose-submaps with transition zones that can depress the stitching error caused by mechanical mispositioning are generated for digital lithographic exposure process.Type: ApplicationFiled: December 22, 2022Publication date: June 27, 2024Applicant: The Hong Kong Polytechnic UniversityInventors: Aping ZHANG, Zuoqin DING, Han WANG, Taige LI
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Patent number: 12019312Abstract: A spectacle lens can inhibit ametropia of the eyes and ensure full visibility. The spectacle lens comprises: first refraction areas and second refraction areas. Each first refraction area has a first refraction force that may be based on a prescription for correcting the ametropia of the eyes. Each second refraction area has a refraction force different from the first refraction force and may function to focus images on the positions except the retina of the eyes, to inhibit the development of the ametropia. Near the central part of the lens, the second refraction areas form a plurality of independent island-shaped areas, and the first refraction areas form the areas beyond the areas of the second refraction areas.Type: GrantFiled: June 29, 2023Date of Patent: June 25, 2024Assignees: HOYA LENS THAILAND LTD., THE HONG KONG POLYTECHNIC UNIVERSITYInventors: Chi Ho To, Siu Yin Lam, Takashi Hatanaka, Yasutake Masuda
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Patent number: 11946523Abstract: A wideband vibration suppression device utilizing properties of a sonic black hole, comprising: a vibration absorber (101) comprising a uniform portion (1011) of a fixed thickness and a conical portion (1012) integrally connected to the uniform portion (1011), the conical portion (1012) extending from the junction in such a manner that the thickness thereof gradually decreases from the thickness (d1) of the uniform portion (1011) to a predetermined thickness (d2); and a damping layer (102) attached to the conical portion (1012) of the vibration absorber (101).Type: GrantFiled: October 17, 2018Date of Patent: April 2, 2024Assignee: THE HONG KONG POLYTECHNIC UNIVERSITYInventors: Li Cheng, Tong Zhou
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Patent number: 11949464Abstract: The present application relates to a dual-polarization-joint noise processing method and device. The present application compensates the discrete spectral coefficient noise on the X polarization state with noise information carried by the discrete spectral eigenvalue on the X, Y polarization states, and a correlation coefficient between the discrete spectral eigenvalue and the discrete spectral coefficient on the X polarization state. Similarly, compensating the discrete spectral coefficient noise on the Y polarization state with noise information carried by the discrete spectral eigenvalue on the X, Y polarization states, and a correlation coefficient between the discrete spectral eigenvalue and the discrete spectral coefficient on the Y polarization state.Type: GrantFiled: December 5, 2022Date of Patent: April 2, 2024Assignee: Shenzhen Research Institute of the Hong Kong Polytechnic UniversityInventors: Chuang Xu, Pak Tao Lau
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Patent number: 11939704Abstract: A woven, water-vapor permeable, water-responsive, shape-memory wool fabric that possesses switchable pore size and shape responsive to varying water content absorbed thereby is demonstrated, more particularly, the wool fabric exerts corresponding thermal and water vapor regulations between the wearer and the surroundings with respect to the temperature and humidity changes.Type: GrantFiled: October 18, 2021Date of Patent: March 26, 2024Assignees: City University of Hong Kong, The Hong Kong Polytechnic UniversityInventors: Jinlian Hu, Mohammad Irfan Iqbal
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Patent number: 11931282Abstract: The present disclosure provides a bracewear for spinal correction and a system for posture training. The system for posture training involves both active and passive corrective forces by using the bracewear and a biofeedback system to address the spinal correction, which can eliminate the adversity of conventional hard braces and reduce the psychological and physiological barriers to treatment.Type: GrantFiled: October 15, 2020Date of Patent: March 19, 2024Assignee: The Hong Kong Polytechnic UniversityInventors: Yiu-Wan Joanne Yip, Yin Ling Sit, Ting Hin Mak, Kit Lun Yick, Tsz Hei Cheung, Sui Pui Ng, Kenny Yat Hong Kwan, Mei Chun Cheung, Ming Fai Chan
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Publication number: 20240088412Abstract: Embodiments of the present disclosure provide a fuel cell power generation device, which includes: a fuel cell with an anode and a cathode, for decomposing hydrogen and generating electric energy through reaction of decomposed hydrogen and oxygen; a first delivery pipe connected between a pipeline of a hydrogen-containing gas and the fuel cell, for delivering the hydrogen-containing gas to the anode of the fuel cell; a first output pipe connected to the fuel cell, for discharging a first remaining gas contacted with the anode of the fuel cell; a second delivery pipe connected to the fuel cell, for delivering an oxygen-containing gas to the cathode of the fuel cell; and a second output pipe connected to the fuel cell, for discharging a second remaining gas contacted with the cathode of the fuel cell.Type: ApplicationFiled: August 4, 2023Publication date: March 14, 2024Applicants: The Hong Kong Polytechnic University, Yee Hop Environmental Protection LimitedInventors: Ka Wai Eric Cheng, Yuk Ping Cho
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Patent number: 11905607Abstract: The present disclosure provides a pure-H2O-fed membrane-electrode assembly (MEA) electrolysis system for electrocatalytic CO2 reduction (ECO2R) to ethylene (C2H4) and C2+ compounds under an industrial applicable continuous flow condition with at least 1000-hour lifetime, and fabrication method thereof.Type: GrantFiled: June 9, 2022Date of Patent: February 20, 2024Assignee: THE HONG KONG POLYTECHNIC UNIVERSITYInventors: Xiaojie She, Shu-Ping Lau
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Patent number: 11885039Abstract: Methods for preparing a monolayer or few-layer centimeter-scale crystalline black phosphorus film, products thereof, and electronic and optoelectronic devices including the same.Type: GrantFiled: May 5, 2022Date of Patent: January 30, 2024Assignee: THE HONG KONG POLYTECHNIC UNIVERSITYInventors: Jianhua Hao, Zehan Wu
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Patent number: 11860043Abstract: In an indoor environment on fire, automatic deployment of sensors disposed on, beneath or over the floor to look upward the ceiling to observe a body of smoke and flame risen near the ceiling allows important information regarding states and dynamics of the body of smoke and flame to be gathered at an early stage of fire (e.g. before arrival of firefighters). By distributing the sensors over the indoor environment, the states and dynamics of the body of smoke and flame are monitored holistically (i.e. as a whole) even at the early stage of fire. Such information is useful to predict development of the fire. In one implementation, a sensor is held in an infrastructure sensor holder mounted on the ceiling during normal time. Upon detecting occurrence of fire, the sensor drops from the holder to land on the floor and orients a sensing direction vertically upward to perform monitoring.Type: GrantFiled: August 24, 2021Date of Patent: January 2, 2024Assignee: THE HONG KONG POLYTECHNIC UNIVERSITYInventors: Qixin Wang, Xinyan Huang, Muhammad Shaheer, Tamzid Mohammad, Xiaoning Zhang, Mingchun Luo, Li-Ta Hsu, Xiqiang Wu, Fu Xiao, Asif Usmani
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Patent number: 11826341Abstract: A method of treating an ocular nerve injury in a subject in need thereof, the method comprising administering a therapeutically effective amount of baicalein or an analog thereof.Type: GrantFiled: February 9, 2022Date of Patent: November 28, 2023Assignees: THE HONG KONG POLYTECHNIC UNIVERSITYInventors: Chi Wai Do, Chi ho To, Li Pan, Dongfeng Chen, Kin-Sang Cho
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Publication number: 20230341708Abstract: A spectacle lens can inhibit ametropia of the eyes and ensure full visibility. The spectacle lens comprises: first refraction areas and second refraction areas. Each first refraction area has a first refraction force that may be based on a prescription for correcting the ametropia of the eyes. Each second refraction area has a refraction force different from the first refraction force and may function to focus images on the positions except the retina of the eyes, to inhibit the development of the ametropia. Near the central part of the lens, the second refraction areas form a plurality of independent island-shaped areas, and the first refraction areas form the areas beyond the areas of the second refraction areas.Type: ApplicationFiled: June 29, 2023Publication date: October 26, 2023Applicants: HOYA LENS THAILAND LTD., THE HONG KONG POLYTECHNIC UNIVERSITYInventors: Chi Ho TO, Siu Yin LAM, Takashi HATANAKA, Yasutake MASUDA
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Patent number: 11768288Abstract: A transparent ultrasound transducer device for multi-mode optical imaging on a target is provided. The device includes a transparent piezoelectric transducer, one or more wires, and an optical lens. The transparent piezoelectric transducer of a first acoustic impedance is configured to receive acoustic waves from the target. The transparent piezoelectric transducer has a first surface and a second surface. The first surface and the second surface are coated with transparent electrically conductive coatings. The optical lens is contacted with and optically coupled to the first surface of the transparent piezoelectric transducer. The optical lens is made of a material with a second acoustic impedance, and the first and second acoustic impedances are substantially similar to minimize an acoustic impedance mismatch such that sensitivity of the device is improved.Type: GrantFiled: March 20, 2023Date of Patent: September 26, 2023Assignee: THE HONG KONG POLYTECHNIC UNIVERSITYInventors: Kwok Ho Lam, Riqiang Lin, Dongliang Shi
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Publication number: 20230295445Abstract: A method of preparing antimicrobial 3D-printed material with antimicrobial agents integrated with the 3D-printed material. The 3D-printed material fabricated with the method of the present disclosure includes antimicrobial agent (s) fully integrated throughout the product and display antimicrobial effect throughout the product, which is resistant to daily wear and tear.Type: ApplicationFiled: September 23, 2020Publication date: September 21, 2023Applicant: The Hong Kong Polytechnic UniversityInventors: Kwan Yu Lo, Chi Wai Kan
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Publication number: 20230273458Abstract: A technology for inhibition of myopia progression adapted to the RPR of the wearer is provided. A spectacle lens and related technology are provided that include a base area that causes a beam that enters through an object-side surface to exit through an eye-side surface and converge on a retina via the eye, and a plurality of defocus areas that each contact the base area and have a characteristic whereby a beam that passes through at least a portion of the defocus area is incident on the retina as a diverging ray, and, in not less than half of the plurality of defocus areas, at least one of a defocus power and a size of each defocus area is set, so as to compensate for a change in retinal spot size due to relative peripheral refraction (RPR) that depends on an eccentricity angle of the eye of the wearer.Type: ApplicationFiled: July 14, 2021Publication date: August 31, 2023Applicants: HOYA LENS THAILAND LTD., THE HONG KONG POLYTECHNIC UNIVERSITYInventors: Hua QI, Chi Ho TO, Siu Yin LAM
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Patent number: 11732403Abstract: Provided herein are methods for preparing metal coated textile substrate by ultrasonic irradiation deposition processes and products thereof.Type: GrantFiled: September 18, 2019Date of Patent: August 22, 2023Assignee: THE HONG KONG POLYTECHNIC UNIVERSITYInventors: Nuruzzaman Noor, Suhas Mutalik
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Patent number: 11726348Abstract: A spectacle lens can inhibit ametropia of the eyes and ensure full visibility. The spectacle lens comprises: first refraction areas and second refraction areas. Each first refraction area has a first refraction force that may be based on a prescription for correcting the ametropia of the eyes. Each second refraction area has a refraction force different from the first refraction force and may function to focus images on the positions except the retina of the eyes, to inhibit the development of the ametropia. Near the central part of the lens, the second refraction areas form a plurality of independent island-shaped areas, and the first refraction areas form the areas beyond the areas of the second refraction areas.Type: GrantFiled: June 21, 2022Date of Patent: August 15, 2023Assignees: THE HONG KONG POLYTECHNIC UNIVERSITY, HOYA LENS THAILAND LTD.Inventors: Chi Ho To, Siu Yin Lam, Takashi Hatanaka, Yasutake Masuda
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Patent number: 11633620Abstract: A method for optogenetics experiments, based on wavefront shaping and including: calculating the transmission matrix between an input end and an output end of the multimode fiber under a fixed shape; implanting the output end into an intracranial space of an experimental subject; and performing wavefront compensation to a light to be input into the input end, according to the spatial position of the optical stimulation and the transmission matrix of the multimode fiber, to form a compensated expanded light, and inputting the compensated expanded light from the input end into the multimode fiber, such that the compensated expanded light, after being transmitted by the multimode fiber to the output end and output from the output end, is capable of focusing at the spatial position of the optical stimulation.Type: GrantFiled: April 8, 2020Date of Patent: April 25, 2023Assignee: THE HONG KONG POLYTECHNIC UNIVERSITY SHENZHEN RESEARCH INSTITUTEInventors: Puxiang Lai, Lei Sun, Tianting Zhong, Zhihai Qiu