Abstract: A spectacle lens can inhibit ametropia of the eyes and ensure full visibility. The spectacle lens comprises: first refraction areas and second refraction areas. Each first refraction area has a first refraction force that may be based on a prescription for correcting the ametropia of the eyes. Each second refraction area has a refraction force different from the first refraction force and may function to focus images on the positions except the retina of the eyes, to inhibit the development of the ametropia. Near the central part of the lens, the second refraction areas form a plurality of independent island-shaped areas, and the first refraction areas form the areas beyond the areas of the second refraction areas.

Abstract: A transparent ultrasound transducer device for multi-mode optical imaging on a target is provided. The device includes a transparent piezoelectric transducer, one or more wires, and an optical lens. The transparent piezoelectric transducer of a first acoustic impedance is configured to receive acoustic waves from the target. The transparent piezoelectric transducer has a first surface and a second surface. The first surface and the second surface are coated with transparent electrically conductive coatings. The optical lens is contacted with and optically coupled to the first surface of the transparent piezoelectric transducer. The optical lens is made of a material with a second acoustic impedance, and the first and second acoustic impedances are substantially similar to minimize an acoustic impedance mismatch such that sensitivity of the device is improved.

Abstract: A method of preparing antimicrobial 3D-printed material with antimicrobial agents integrated with the 3D-printed material. The 3D-printed material fabricated with the method of the present disclosure includes antimicrobial agent (s) fully integrated throughout the product and display antimicrobial effect throughout the product, which is resistant to daily wear and tear.

Abstract: A technology for inhibition of myopia progression adapted to the RPR of the wearer is provided. A spectacle lens and related technology are provided that include a base area that causes a beam that enters through an object-side surface to exit through an eye-side surface and converge on a retina via the eye, and a plurality of defocus areas that each contact the base area and have a characteristic whereby a beam that passes through at least a portion of the defocus area is incident on the retina as a diverging ray, and, in not less than half of the plurality of defocus areas, at least one of a defocus power and a size of each defocus area is set, so as to compensate for a change in retinal spot size due to relative peripheral refraction (RPR) that depends on an eccentricity angle of the eye of the wearer.

Abstract: Provided herein are methods for preparing metal coated textile substrate by ultrasonic irradiation deposition processes and products thereof.

Abstract: A spectacle lens can inhibit ametropia of the eyes and ensure full visibility. The spectacle lens comprises: first refraction areas and second refraction areas. Each first refraction area has a first refraction force that may be based on a prescription for correcting the ametropia of the eyes. Each second refraction area has a refraction force different from the first refraction force and may function to focus images on the positions except the retina of the eyes, to inhibit the development of the ametropia. Near the central part of the lens, the second refraction areas form a plurality of independent island-shaped areas, and the first refraction areas form the areas beyond the areas of the second refraction areas.

Abstract: A method for optogenetics experiments, based on wavefront shaping and including: calculating the transmission matrix between an input end and an output end of the multimode fiber under a fixed shape; implanting the output end into an intracranial space of an experimental subject; and performing wavefront compensation to a light to be input into the input end, according to the spatial position of the optical stimulation and the transmission matrix of the multimode fiber, to form a compensated expanded light, and inputting the compensated expanded light from the input end into the multimode fiber, such that the compensated expanded light, after being transmitted by the multimode fiber to the output end and output from the output end, is capable of focusing at the spatial position of the optical stimulation.

Abstract: A method and an apparatus for sending key-value pair data are provided, and a method and an apparatus for collecting key-value pair data are provided. In the method, first target key-value pair data is perturbed as first perturbed key-value pair data, so that a data collector can determine, based on a value a or b of a first value in the first perturbed key-value pair data, whether to include the entire first perturbed key-value pair data into the statistical result in a process of generating the statistical result. In this way, an association between a value and a key in the key-value pair data is reserved in the first perturbed key-value pair data, which improves availability of the first perturbed key-value pair data. That is, a statistical result generated by the data collector based on the first perturbed key-value pair data is closer to a statistical result generated based on original user key-value pair data.

Abstract: A transparent ultrasound transducer device for multi-mode optical imaging on a target is provided. The device includes a transparent piezoelectric transducer, one or more wires, and an optical lens. The transparent piezoelectric transducer of a first acoustic impedance is configured to receive acoustic waves from the target. The transparent piezoelectric transducer has a first surface and a second surface. The first surface and the second surface are coated with transparent electrically conductive coatings. The optical lens is contacted with and optically coupled to the first surface of the transparent piezoelectric transducer. The optical lens is made of a material with a second acoustic impedance, and the first and second acoustic impedances are substantially similar to minimize an acoustic impedance mismatch such that sensitivity of the device is improved.

Abstract: A medical device that includes a carrier member, one or more operative components disposed in the carrier member, an optical fiber at least partly disposed in the carrier member, and at least one fiber Bragg grating (FBG) sensor array associated with the optical fiber and disposed in the carrier member. The carrier member includes an insertion end and side walls that contact the subject's body during positioning of the carrier member in the subject's body. The at least one FBG sensor array measures contact forces at one or both of the insertion end and along the side walls of the carrier member during positioning of the carrier member in the subject's body. A multi-core optical fiber configured for use in a medical device for positioning in a subject's body is also provided. A system and method for guiding positioning of a medical device in a subject's body is also provided.

Abstract: The present disclosure describes a system, method and software applications for predicting the KAM of a subject for a plurality of gait cycles of a subject. At least one sensor attachable adjacent to the ankle of at least one leg of the subject provides accelerometer and gyroscopic data for the plurality of gait cycles. A processing means receives subject parameters and accelerometer and gyroscopic data from the at least one sensor for evaluation by a neural network of predicted KAM values for the plurality of gait cycles of the subject. The neural network is configured via determining KAM values for each of the plurality of subjects from measurements during a plurality of gait cycles and other parameters.

Abstract: This invention relates to compounds of formula 1, 2 or 3 a pharmaceutically acceptable salt, or solvate thereof, wherein X1, Y, R1, R2, R3, R4, and R5 are as defined herein. The compounds are antimicrobial agents that may be used to treat various bacterial and protozoal infections and disorders related to such infections. The invention also relates to pharmaceutical compositions containing the compounds and to methods of treating bacterial and protozoal infections by administering the compounds of formula 1, 2 or 3.

Abstract: The present disclosure provides an effective stress cell for direct measurement of effective stress in saturated soil. The effective stress cell comprises a sensing diaphragm, a porous diaphragm, a connector and a strain sensor. The porous diaphragm allows pore-water to enter the interior space between the sensing diaphragm and the porous diaphragm to provide complete balance of pore-water pressures in the front and back of the sensing diaphragm. Thus, the effective stress cell can directly and accurately measure the effective stress in saturated soil using only one diaphragm at one location without measuring pore-water pressure.

Abstract: A machine learning method predicts whether a specified subject is at high risk of developing cognitive impairment based upon a data record for said specified subject, and a method of training a dual neural network for such. These methods may work by automatically classifying said subject into a first class associated with a first predicted risk of cognitive impairment or a second class associated with a second predicted risk of cognitive impairment. Subject records are obtained comprising a first set of measured data and a second set of data including results for two or more health assessment questionnaires; and a label indicating that the subject belongs to the first class or second class. These records are used to train first and second neural networks, and in the latter method these trained networks are able to predict whether a specified subject should belong to said first class or second class.

Abstract: A spectacle lens can inhibit ametropia of the eyes and ensure full visibility. The spectacle lens comprises: first refraction areas and second refraction areas. Each first refraction area has a first refraction force that may be based on a prescription for correcting the ametropia of the eyes. Each second refraction area has a refraction force different from the first refraction force and may function to focus images on the positions except the retina of the eyes, to inhibit the development of the ametropia. Near the central part of the lens, the second refraction areas form a plurality of independent island-shaped areas, and the first refraction areas form the areas beyond the areas of the second refraction areas.

Abstract: This disclosure provides a biodegradable antimicrobial material based on polylactic acid oligomer represented by formula 1 as an active ingredient. The disclosure also provides a process for preparing the polylactic acid oligomer and an antimicrobial product prepared therefrom.

Abstract: The present invention relates to the preparation of a series of chiral DOTA, DO3A, DO2A, DO1A, cyclen and their metal complexes, which display properties superior to those of previous DOTA-based compounds, and hence are potentially valuable as a platform for diagnostic applications. The chiral DOTAs reveal a high abundance of twisted square antiprism (TSA) geometry favoring them to be used as potential MRI contrast agents, whereas their rapid labelling properties at mild conditions make them excellent candidates for use as radiometal chelators.

Abstract: Disclosed is an apparatus for the batch polishing of workpieces, the apparatus includes an annular cavity, in which several workpieces are mounted, magnetic abrasives, which are arranged in the annular cavity and used for polishing the workpieces, and multiple magnet sets, which are used for generating a magnetic field for the magnetic abrasives in order to remove a surface material of the workpieces, wherein each of the magnet sets comprises magnets arranged on both inner and outer sides of the annular cavity and configured to rotate about the axis of the annular cavity.

Abstract: Methods and systems for storing digital data into peptide sequences and retrieving digital data from peptide sequences are disclosed. The method for storing digital data into peptide sequences may include: encoding the digital data into a digital code; translating the digital code into the peptide sequences; and synthesizing the translated peptide sequences. The method for retrieving digital data from peptide sequences may include: sequencing and determining an order of the peptide sequences; converting the peptide sequences with the determined order into a digital code; and decoding the digital data from the digital code. Codes with error-correction capability are developed for encoding digital data into peptide sequences, and a computational method implemented in a software is developed for sequencing the digital data bearing peptides.

Abstract: The present technology for the detection and analysis of analytes within a sample is based on molecular biology methods, including western blotting, gel electrophoresis, mass spectrometry, enzyme-linked immunosorbent assays and RT-PCR, which are normally time-consuming and laborious. The present disclosure provides novel OECT based electrochemical biosensors that can enable the convenient and cost-effective determination of analytes within a sample with high sensitivity and selectivity.