Patents Assigned to The Queen's University of Belfast
  • Publication number: 20130034891
    Abstract: A process is described for the preparation of water-soluble cellulose hydrolysis product. The process comprise admixing cellulose with an ionic liquid capable of solvating or dissolving at least some of the cellulose, said ionic liquid being a compound comprises solely of cations and anions and which exists in a liquid state at a temperature at or below 150° C., and in which the anions are selected from halide and cyanate; and treating the resulting solvate or solution with an acid in the presence of water, said acid having a pKa in water of less than 2 at 25° C.
    Type: Application
    Filed: October 11, 2012
    Publication date: February 7, 2013
    Applicant: The Queen's University of Belfast
    Inventors: Markus Fanselow, John Holbrey, Kenneth Richard Seddon
  • Patent number: 8338159
    Abstract: A novel astrovirus designated chicken astrovirus type 3 has been isolated and characterized. Nucleotide sequences and polypeptide sequences of this astrovirus are provided with uses of the same and the isolated astrovirus in assay kits and vaccines.
    Type: Grant
    Filed: January 4, 2007
    Date of Patent: December 25, 2012
    Assignee: The Queen's University of Belfast
    Inventors: Daniel Todd, Brian Adair, Mildred Wylie, Neris Ball
  • Patent number: 8321751
    Abstract: An apparatus (1) for implementing a cyclic redundancy check (CRC) error detection methodology to compute a CRC error detection code for data according to the methodology, comprising computation means (2) which uses parallel computation (4) to compute the CRC error detection code, and configurator means (3) which uses the CRC error detection methodology to determine a configuration of the computation means required to compute the CRC error detection code, and configures (25) the computation means accordingly, wherein the configurator means is able to use each of a plurality of CRC error detection methodologies to determine a configuration of the computation means required for parallel computation of a CRC error detection code according to each of the methodologies, and the computation means is configurable to allow configuration thereof for parallel computation of each CRC error detection code.
    Type: Grant
    Filed: April 13, 2007
    Date of Patent: November 27, 2012
    Assignee: The Queen's University of Belfast
    Inventors: Sakir Sezer, Ciaran Toal
  • Publication number: 20120295851
    Abstract: Described is an N-terminal hexapeptide fragment of maximakinin, QUB 698.8, which exhibits potent tissue selective actions on smooth muscle. It demonstrates a high degree of selectivity for arterial smooth muscle over small intestinal smooth muscle, causing potent relaxation of arterial smooth muscle, while causing less potent contraction of ileal smooth muscle. It may be used treatment of diseases of the cardiovascular system and in promotion of angiogenesis.
    Type: Application
    Filed: June 22, 2012
    Publication date: November 22, 2012
    Applicant: The Queen's University of Belfast
    Inventors: Christopher Shaw, Tianbao Chen, Martin O'Rourke, Brian Walker, David Hirst
  • Patent number: 8284101
    Abstract: A retrodirective antenna system (1) for receiving an incoming signal (15) from an object (13) and directing an outgoing signal (11) back to the object (13), comprising two or more transceiver cells (3), each of which receives a part of the incoming signal, produces a phase conjugate output signal, which output signals from the cells combine to form an outgoing signal (11) directed back to the object (13), wherein each transceiver cell (3) comprises an antenna component (7) which detects the part of the incoming signal, a processor which receives the part of the incoming signal and produces first and second same-side, sideband (SB) signals of the part of the incoming signal, a phase shift system comprising a first phase element which receives the first SB signal and outputs a SB signal having a first phase, and a second phase element which receives the second SB signal and outputs a SB signal having a second phase which is in quadrature with the first phase, and an IQ modulator comprising an I input port, a Q
    Type: Grant
    Filed: May 1, 2009
    Date of Patent: October 9, 2012
    Assignee: The Queen's University of Belfast
    Inventor: Vincent Francis Fusco
  • Patent number: 8217011
    Abstract: Described is an N-terminal hexapeptide fragment of maximakinin, QUB 698.8, which exhibits potent tissue selective actions on smooth muscle. It demonstrates a high degree of selectivity for arterial smooth muscle over small intestinal smooth muscle, causing potent relaxation of arterial smooth muscle, while causing less potent contraction of ileal smooth muscle. It may be used treatment of diseases of the cardiovascular system and in promotion of angiogenesis.
    Type: Grant
    Filed: March 7, 2008
    Date of Patent: July 10, 2012
    Assignee: The Queen's University of Belfast
    Inventors: Christopher Shaw, Tianbao Chen, Martin O'Rourke, Brian Walker, David Hirst
  • Publication number: 20120046244
    Abstract: Disclosed herein are ionic liquid compositions comprising active pharmaceutical, biological, and nutritional compounds, and methods of use. Further disclosed are compositions of matter including liquid ion pairs alone or in solution and their use; compositions of ionic liquids that are ‘solvated,’ for example, ‘hydrated’ and their uses.
    Type: Application
    Filed: December 29, 2009
    Publication date: February 23, 2012
    Applicants: THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ALABAMA, QUEEN'S UNIVERSITY BELFAST, MONASH UNIVERSITY
    Inventors: Robin D. Rogers, Daniel T. Daly, Douglas MacFarlane, Janet L. Scott, Kenneth R. Seddon, Gabriela Gurau, Katharina Bica, Jelena Turanjanin, Pamela M. Dean
  • Publication number: 20120029247
    Abstract: A process is described for the preparation of water-soluble cellulose hydrolysis products, which comprises admixing cellulose with an ionic liquid capable of solvating or dissolving at least some of the cellulose, said ionic liquid being a compound comprised solely of cations and anions and which exists in a liquid state at a temperature at or below 15O° C.
    Type: Application
    Filed: September 3, 2008
    Publication date: February 2, 2012
    Applicant: The Queen's University of Belfast
    Inventors: John Holbrey, Markus Fanselow, Kenneth Richard Seddon, Laurent Vanoye, Anna Zheng
  • Publication number: 20110312048
    Abstract: A process is described for the preparation of water-soluble cellulose hydrolysis products The process comprises admixing cellulose with an ionic liquid capable of solvating or dissolving at least some of the cellulose, said ionic liquid being a compound comprised solely of cations and anions and which exists in a liquid state at a temperature at or below 15O° C., and in which the anions are selected from sulfate, hydrogen sulfate and nitrate; and treating the resulting solvate or solution with an acid in the presence of water, said acid having a pKa in water of less than 2 at 25° C.
    Type: Application
    Filed: September 3, 2008
    Publication date: December 22, 2011
    Applicant: THE QUEEN'S UNIVERSITY OF BELFAST
    Inventors: Markus Fanselow, John Holbrey, Kenneth Richard Seddon, Laurent Vanoye, Anna Zheng
  • Publication number: 20110251050
    Abstract: A method of ageing a catalyst material includes at least the steps of: (a) heating a gaseous stream; (b) adding a least one pure hydrocarbon gas and an oxygen-containing gas to the heated gaseous stream to provide a combined stream; and (c) passing the combined stream through the catalyst material. The use of at least one pure hydrocarbon gas and an oxygen-containing gas allows maximum re-circulation of the exit stream from the catalyst material for reuse, while maintaining the correct C, H and O proportions being provided in the combined stream to replicate realistic use of the catalyst material.
    Type: Application
    Filed: December 11, 2009
    Publication date: October 13, 2011
    Applicant: The Queen's University of Belfast
    Inventors: Roy Douglas, Andrew Woods
  • Patent number: 8032543
    Abstract: A sorting apparatus and method for sorting units into a unit storage structure in accordance with a pre-determined order, the sorting apparatus comprising a unit search structure containing a record of units in the unit storage structure, and a unit location pointer structure containing location pointers for units in the unit storage structure, wherein the sorting apparatus receives a unit being sorted, the unit search structure reads the unit being sorted, uses its record of units in the unit storage structure to search for a closest matching unit to the unit being sorted, accesses the unit location pointer structure and retrieves a location pointer for the closest matching unit, and the sorting apparatus uses the location pointer of the closest matching unit to access the unit storage structure and to place the unit being sorted into the unit storage structure in an appropriate position in accordance with the pre-determined order.
    Type: Grant
    Filed: December 5, 2006
    Date of Patent: October 4, 2011
    Assignee: The Queen's University of Belfast
    Inventors: Sakir Sezer, Kieran McLaughlin
  • Patent number: 8025676
    Abstract: Provided is a method of producing a bioabsorbable, implantable substrate having a graded molecular weight distribution, comprising exposing at least a portion of the implantable substrate to electron beam irradiation. There is also provided a bioabsorbable, implantable substrate comprising a bioabsorbable polymer having a graded molecular weight distribution through at least a portion of its thickness.
    Type: Grant
    Filed: February 10, 2005
    Date of Patent: September 27, 2011
    Assignee: The Queen's University of Belfast
    Inventor: Fraser James Buchanan
  • Patent number: 8003610
    Abstract: A bradykinin B2-receptor antagonist peptide, kinestatin, isolated from toad (Bombina maxima) defensive skin secretion, and analogs thereof, is disclosed. The structure of kinestatin is pGlu-Leu/Ile-Pro-Gly-Leu/Ile-Gly-Pro-Leu/Ile-Arg-NH2. Also disclosed are kinestatin analogs, prodrugs including the peptides, fusion peptides and multimeric peptides including the peptide sequences, pharmaceutical compositions including kinestatin and analogs thereof, prodrugs, fusion and multimeric peptides thereof, nucleic acids encoding kinestatin and analogs thereof, and nucleic acids encoding the fusion and multimeric peptides. Kinestatin and analogs thereof (including the prodrugs and multimeric and/or fusion peptides) can be used to treat and/or prevent disorders associated with bradykinin, including cardiovascular disorders, inflammation, asthma, allergic rhinitis, pain, angiogenesis and the like.
    Type: Grant
    Filed: February 6, 2004
    Date of Patent: August 23, 2011
    Assignee: Queen's University of Belfast
    Inventors: Chris Shaw, David Hirst, Tianbao Chen, Martin O'Rourke, Pingfan Rao
  • Publication number: 20110202324
    Abstract: A method for estimating a radiation dose and distribution for a target volume is provided. The method includes receiving a simulated dose array (606) describing a plurality of simulated dose values for a plurality of voxels in the target volume, generating an energy deposition coefficient function for the plurality of voxels (608), and obtaining a raw fluence array based at least on the simulated dose array and the energy deposition coefficient function (612). The method also includes generating an adjusted fluence array (613) based on the raw fluence array and at least one adjustment criteria, and generating an adjusted dose array (622) for the target volume based on the adjusted fluence array and the energy deposition coefficient function.
    Type: Application
    Filed: October 19, 2009
    Publication date: August 18, 2011
    Applicants: Vanderbilt University, The Queens University of Belfast
    Inventors: Fred Currell, Marcus Mendenhall
  • Patent number: 7982686
    Abstract: A freestanding frequency selective surface (FSS) is provided which comprises at least one shorted resonance aperture element (12). The shorted resonance aperture element provides a sensitivity to polarization. The shorted resonance aperture element may comprise at least one short, which may enable the FSS to be freestanding. The invention further provides an FSS device comprising at least one array of the freestanding frequency selective surfaces, and a method of forming the freestanding frequency selective surfaces.
    Type: Grant
    Filed: March 16, 2006
    Date of Patent: July 19, 2011
    Assignee: The Queen's University of Belfast
    Inventors: Robert Cahill, Raymond John Dickie, Vincent Francis Fusco, Harold Samuel Gamble
  • Patent number: 7972492
    Abstract: Disclosed is a process for the electrochemical transformation of a compound to form a product, the process comprising (i) effecting the transformation in the presence of an electrolyte comprising at least one room temperature ionic liquid, wherein the ionic liquid is air-stable and moisture-stable, (ii) recovering the product, and optionally (iii) recovering the ionic liquid. The process can be used to effect the electrochemical transformation of a wide range of organic compounds.
    Type: Grant
    Filed: July 8, 2002
    Date of Patent: July 5, 2011
    Assignee: The Queen's University of Belfast
    Inventors: William R. Pitner, Kenneth R. Seddon, Kenneth M. Stack, Alan Curzons, Richard Freer
  • Patent number: 7928031
    Abstract: Disclosed is a catalyst composition based on an indium salt and an organic ionic liquid, a process for making the catalyst composition, and uses thereof. The catalyst composition is particularly suitable for Lewis acid catalysed electrophilic aromatic substitution reactions, such as Friedel-Crafts alkylation reactions an Friedel-Crafts acylation reactions.
    Type: Grant
    Filed: October 2, 2002
    Date of Patent: April 19, 2011
    Assignee: The Queen's University of Belfast
    Inventors: Kenneth Richard Seddon, Christopher Hardacre, Barry Joseph McAuley
  • Publication number: 20100256020
    Abstract: The invention provides a wellbore fluid which comprises an aqueous continuous phase and, dissolved in said aqueous continuous phase, at least one salt containing an imidazolium cation having at least 6 carbon atoms, and a method of carrying out a wellbore operation, which comprises introducing into a wellbore in a clay-containing formation, a wellbore fluid according to the invention. The described salts are effective shale inhibitors.
    Type: Application
    Filed: November 27, 2008
    Publication date: October 7, 2010
    Applicant: The Queen's University of Belfast
    Inventors: Mark Aston, Kenneth Richard Seddon, David Francis Wassell
  • Publication number: 20100256019
    Abstract: The invention provides a wellbore fluid which comprises an aqueous continuous phase and, dissolved in said aqueous continuous phase, at least one salt which exists in a liquid state at a temperature below 150° C. and which has an ammonium, phosphonium or sulfonium cation containing at least 5 carbon atoms, or a quaternised nitrogen-containing heterocyclic cation containing at least 6 carbon atoms; provided that said salt is not 2-hydroxy-N,N,N-trimethyl ethanaminium acetate; and a method of carrying out a wellbore operation, which comprises introducing into a wellbore in a clay-containing formation, a wellbore fluid according to the invention. The described salts are effective shale inhibitors.
    Type: Application
    Filed: November 27, 2008
    Publication date: October 7, 2010
    Applicant: The Queen's University of Belfast
    Inventors: Mark Aston, Kenneth Richard Seddon, David Francis Wassell
  • Publication number: 20100249035
    Abstract: Described is an N-terminal hexapeptide fragment of maximakinin, QUB 698.8, which exhibits potent tissue selective actions on smooth muscle. It demonstrates a high degree of selectivity for arterial smooth muscle over small intestinal smooth muscle, causing potent relaxation of arterial smooth muscle, while causing less potent contraction of ileal smooth muscle. It may be used treatment of diseases of the cardiovascular system and in promotion of angiogenesis.
    Type: Application
    Filed: March 7, 2008
    Publication date: September 30, 2010
    Applicant: The Queen's University of Belfast
    Inventors: Christopher Shaw, Tianbao Chen, Martin O'Rourke, Brian Walker, David Hirst