Patents Assigned to The Queen's University of Belfast
  • Publication number: 20080317662
    Abstract: A molten salt and process for preparing a molten salt or hydrogen peroxide uses ionic hydroquinones or hydroquinone derivatives as O2 reduction catalysts.
    Type: Application
    Filed: June 30, 2005
    Publication date: December 25, 2008
    Applicant: THE QUEENS UNIVERSITY OF BELFAST
    Inventor: Andrew P. Doherty
  • Publication number: 20080306319
    Abstract: The application discloses novel processes for the oligomerisation of unsaturated hydrocarbons, and more specifically the use of selected ionic liquids in the oligomerisation of unsaturated hydrocarbons, which allows for selection of the oligomers formed.
    Type: Application
    Filed: December 12, 2006
    Publication date: December 11, 2008
    Applicant: The Queen's University of Belfast
    Inventors: Martyn John Earle, Johanna Karkkainen, Natalia V. Plechkova, Alina Tomaszowska, Kenneth Richard Seddon
  • Publication number: 20080268435
    Abstract: A method of predicting the presence of a non-functional BRCA1 gene in a biological sample, comprises the step of assaying the sample for expression of at least one specific member of the S100 family of genes. The invention also describes a kit for predicting the presence of non-functional BRCA1, comprising means for assaying a sample for expression of at least one specific member of the S100 gene family. A method of detecting a genetic predisposition to cancer is also described, comprising the step of assaying a biological sample for expression of a specific member of the S100 family of genes. Also described is a method of determining a suitable chemotherapeutic agent for an individual.
    Type: Application
    Filed: June 6, 2005
    Publication date: October 30, 2008
    Applicant: THE QUEEN'S UNIVERSITY OF BELFAST
    Inventor: Paul Harkin
  • Publication number: 20080204355
    Abstract: A freestanding frequency selective surface (FSS) is provided which comprises at least one shorted resonance aperture element (12). The shorted resonance aperture element provides a sensitivity to polarisation. The shorted resonance aperture element may comprise at least one short, which may enable the FSS to be freestanding. The invention further provides an FSS device comprising at least one array of the freestanding frequency selective surfaces, and a method of forming the freestanding frequency selective surfaces.
    Type: Application
    Filed: March 16, 2006
    Publication date: August 28, 2008
    Applicant: THE QUEEN'S UNIVERSITY OF BELFAST
    Inventors: Robert Cahill, Raymond John Dickie, Vincent Francis Fusco, Harold Samuel Gamble
  • Patent number: 7344699
    Abstract: A drug conjugate comprising a targeting agent and an anti-cancer agent, wherein said targeting agent comprises an erythropoietin receptor ligand, is described. The drug conjugate can be used in methods of treating cancer. Also described are methods of treating cancer using the conjugate, methods of diagnosis, methods of imaging and pharmaceutical compositions.
    Type: Grant
    Filed: May 21, 2003
    Date of Patent: March 18, 2008
    Assignee: The Queen's University of Belfast
    Inventors: Terence Lappin, John Mann, Michael McManus, Perry Maxwell
  • Publication number: 20080054223
    Abstract: Complex salts, based on ionic liquids, which exhibit at least one light emitting property selected from (a) fluorescence, (b) phosphorescence, and (c) electroluminescence when in the solid state; and which have a melting point below 250° C.
    Type: Application
    Filed: October 24, 2005
    Publication date: March 6, 2008
    Applicant: The Queen's University of Belfast
    Inventors: Martyn Earle, Kenneth Seddon
  • Patent number: 7321263
    Abstract: A class E power amplifier circuit comprising an active device, a DC blocking element and an oscillating element, wherein the oscillating element is driven by a voltage signal.
    Type: Grant
    Filed: February 24, 2005
    Date of Patent: January 22, 2008
    Assignee: Queen's University of Belfast
    Inventors: Thorsten Brabetz, Vincent Francis Fusco
  • Patent number: 7289573
    Abstract: Method and apparatus for providing an amplified modulated radio frequency signal, the method comprising the steps of providing a radio frequency (RF) oscillatory signal, generating from the RF oscillatory signal and an input signal a pair of phase modulated phase conjugated signals, and summing the pair of signals to provide the desired modulated RF signal output. A form of the invention is applied to digital modulation using in-phase (I) and quadrature (Q) input signals. Each of the I and Q signals is processed in a respective channel, with the channel outputs being summed. The channels share an RF oscillatory signal, which is phase shifted by 90 degrees within the Q channel.
    Type: Grant
    Filed: February 26, 2003
    Date of Patent: October 30, 2007
    Assignee: The Queens University of Belfast
    Inventors: Vincent Francis Fusco, Thorsten Brabetz
  • Patent number: 7277061
    Abstract: An antenna comprises a polarizer, a phasing network and a field radiating element such as a horn. The polarizer and phasing network generate a plurality of phase shifted circularly polarised waves which are superimposed to produce multiple antenna field patterns from a single antenna aperture.
    Type: Grant
    Filed: March 3, 2005
    Date of Patent: October 2, 2007
    Assignee: The Queens University of Belfast
    Inventors: Vincent Francis Fusco, Bandaru Subbarao
  • Publication number: 20070129319
    Abstract: Described is a novel human deubiquitinating enzyme, DUB-3, (SEQ ID NO: 1), and variants and fragments thereof. Also described are nucleic acid molecules encoding the enzyme, and use of the polypeptide and nucleic acid molecules in treatment of cancer, assays.
    Type: Application
    Filed: November 12, 2004
    Publication date: June 7, 2007
    Applicant: The Queen's University of Belfast
    Inventors: James Burrows, Michael McGrattan, James Johnston
  • Publication number: 20070105164
    Abstract: The invention relates to an oncofetal glycoprotein, referred to as MQ-1, nucleic acid sequences coding for the protein, and antibodies which bind specifically to the protein. Also described is a hybridoma capable of producing monoclonal antibodies which bind specifically to the protein of the invention. Methods, and kits, for diagnosing and treating cancer using the antibodies of the invention are also described. Anti-sense polynucleotides are also described, as are methods for inducing apoptosis in cells which express MQ-1.
    Type: Application
    Filed: November 15, 2004
    Publication date: May 10, 2007
    Applicant: The Queen's University of Belfast
    Inventors: Karl Mulligan, Derek McCormick, Patrick Johnston
  • Patent number: 7204058
    Abstract: A flat-formed arch ring unit includes a linear array of voussoir portions connected along their upper edges. The unit is then archable. A method is provided for forming an archway including the steps of arching one or more the flat formed arch ring units and locating them between two or more foundation blocks or the like. This provides a simple yet effective process and unit for forming an archway. With ease of production, shaping and transportation, making new archways or carrying out repairs of existing bridge archways is significantly faster and cheaper, minimizing disruption and delay to traffic.
    Type: Grant
    Filed: May 12, 2005
    Date of Patent: April 17, 2007
    Assignee: The Queen's University of Belfast
    Inventor: Adrian Ernest Long
  • Patent number: 7119235
    Abstract: According to one aspect of the invention, there is provided the use of an organic ionic liquid in a zeolite-catalysed process, for example an acylation, alkylation, isomerisation or hydrocracking process in which zeolites act as catalysts or catalyst precursors, especially Friedel-Crafts alkylation and acylation procedures.
    Type: Grant
    Filed: October 2, 2002
    Date of Patent: October 10, 2006
    Assignee: The Queen's University of Belfast
    Inventors: Christopher Hardacre, David W. Rooney, Jillian M. Thompson, Suhas P. Katdare
  • Patent number: 7094925
    Abstract: A process for the oxidation of an alkyl-aromatic compound, wherein the aromatic compound is admixed with an oxidising agent or sulfur compound in the presence of an ionic liquid is described. In this process, air, dioxygen, peroxide, superoxide, any other form of active oxygen, nitrite, nitrate, nitric acid or other oxides (or oxyhalides) of nitrogen (hydrate or anhydrous) are preferably used as the oxidising agent. The process is usually under Bronsted acidic conditions. The product of the oxidation reaction is preferably a carboxylic acid or ketone or an intermediate compound in the oxidation such as an aldehyde, or alcohol. The oxidation is preferably performed in an ionic liquid containing an acid promoter such as methanesulfonic acid.
    Type: Grant
    Filed: October 5, 2001
    Date of Patent: August 22, 2006
    Assignee: The Queen's University of Belfast
    Inventors: Martyn John Earle, Suhas Prabhakar Katdare
  • Patent number: 7084317
    Abstract: A process for the halogenation of an aromatic compound wherein the aromatic compound is admixed with a halogenating agent in the presence of an ionic liquid is described. The method in preferably halide, sulfur or nitrate ionic liquids has significant advantages over conventional halogenation reactions. These are that the reaction starts with, e.g., a halide salt rather than, e.g., a halogen, and is therefore more convenient and safer. Also, when the reaction is performed in a nitrate ionic liquid, the only by-product is water.
    Type: Grant
    Filed: October 5, 2001
    Date of Patent: August 1, 2006
    Assignee: The Queen's University of Belfast
    Inventors: Martyn John Earle, Suhas Prabhakar Katdare
  • Publication number: 20060147538
    Abstract: The invention relates to a drug delivery composition comprising an active ingredient and a biologically inert material wherein the biologically inert material is a nanocomposite material. Preferably the biologically inert material is a polymer-clay nanocomposite comprising up to about 40% by weight of nano-sized (1-1000 nm) clay particles dispersed in a polymeric material. The active ingredient may be dispersed in the nanocomposite material or absorbed thereto.
    Type: Application
    Filed: November 4, 2005
    Publication date: July 6, 2006
    Applicant: THE QUEEN'S UNIVERSITY OF BELFAST
    Inventors: Duncan Q.M. Craig, John Anthony McNally
  • Patent number: 7009077
    Abstract: A process for the sulfonation of an aromatic compound wherein the aromatic compound and sulfonating agent are admixed in the presence of an ionic liquid is described. The method for the sulfonation of aromatic compounds in (e.g. water stable) ionic liquids offers advantages over conventional sulfonation reactions. These are that no by-products form, the ionic liquid is not consumed, and the sulfonating agent (e.g. SO3) is relatively inexpensive.
    Type: Grant
    Filed: October 5, 2001
    Date of Patent: March 7, 2006
    Assignee: The Queen's University of Belfast
    Inventors: Martyn John Earle, Suhas Prabhakar Katdare
  • Patent number: 6998497
    Abstract: A metal bis-triflimide compound having the formula: [Mx]n+[(N(SO2CF3)2)(nx?yz)](nx?yz)?[Ly]z? where M is a metal selected from the metals in groups 5 to 10, 12 and 14 to 16 and Cu, Au, Ca, Sr, Ba, Ra, Y, La, Ac, Hf, Rf, Ga, In, Tl, Ce, Pr, Nd, Pm, Sm, Eu, Gd, Tb, Dy, Ho, Er, Tm, Lu and the actinides; L is a negative or neutral ligand; n is 2,3,4,5,6,7 or 8; x is greater than or equal to 1 y is 0,1,2,3,4,5,6,7 or 8; and z is 0,1,2,3 or 4.
    Type: Grant
    Filed: March 12, 2002
    Date of Patent: February 14, 2006
    Assignee: The Queen's University of Belfast
    Inventors: Martyn J. Earle, Barry Joseph Mcauley, Alwar Ramani, Kenneth Richard Seddon, Jillian M. Thomson
  • Patent number: 6995136
    Abstract: A peptide factor, its analogs and methods of using such peptide factor derived from murine epidermal growth factor peptide is disclosed wherein the peptide factor is modified to protect it from proteolytic degradation and the peptide binds to laminin receptors.
    Type: Grant
    Filed: April 21, 1999
    Date of Patent: February 7, 2006
    Assignee: The Queen's University of Belfast
    Inventors: John Nelson, Brian Walker, Neil McFerran, Patrick Harriott
  • Patent number: 6939974
    Abstract: The disclosure herein relates to imidazole carbenes and imidazole carbene salts. The disclosure also relates to the synthesis of imidazole carbenes and imidazole carbene salts. The imidazole carbenes disclosed include those synthesized by reacting an imidazole halide with a base under reduced pressure. The imidazole carbene salts disclosed include those synthesized by reaction of imidazole carbenes with an acid or alcohol suitable for creation of a salt. The disclosure also relates to the use of imidazole carbenes and imidazole carbene salts for the synthesis of organic liquids.
    Type: Grant
    Filed: April 5, 2001
    Date of Patent: September 6, 2005
    Assignee: The Queens University of Belfast
    Inventors: John Martyn Earle, Richard Kenneth Seddon