Abstract: Portable common path shearing interferometry-based holographic microscopy systems are disclosed herein. In one embodiment, a system is configured for positioning a laser light source, a sample holder, a microscope objective lens, a shear plate and the imaging device in a common path shearing interferometry configuration. In some embodiments, the systems are relatively small and lightweight and exhibit good temporal stability. In one embodiment, a system for automatic cell identification and visualization using digital holographic microscopy using an augmented reality display device can include an imaging device mounted to an augmented reality display device, configured to capture one or more images of the hologram of the sample disposed on the sample holder illuminated by a beam. The augmented reality display device can include a display and can be configured to render a pseudo-colored 3D visualization of the sample and information associated with the sample, on the display.

Abstract: The present disclosure provides improved systems and methods for automated cell identification/classification. More particularly, the present disclosure provides advantageous systems and methods for automated cell identification/classification using shearing interferometry with a digital holographic microscope. The present disclosure provides for a compact, low-cost, and field-portable 3D printed system for automatic cell identification/classification using a common path shearing interferometry with digital holographic microscopy. This system has demonstrated good results for sickle cell disease identification with human blood cells. The present disclosure provides that a robust, low cost cell identification/classification system based on shearing interferometry can be used for accurate cell identification.

Abstract: A system and method for outage prediction for electrical distribution utilities using high-resolution weather forecasts, geographic data (e.g., land use and vegetation around overhead-lines) and utility infrastructure data (e.g., transformer fuses, etc.) to predict distributed outage occurrences (e.g., number of outages over a 2-km gridded map) in advance of a storm.

Abstract: Aspects of the subject disclosure may include, for example, embodiments include obtaining a first estimated bandwidth capacity of a communication network and selecting a target buffer level to temporarily store media content. Further embodiments include requesting a first portion of the media content according to the first estimated bandwidth capacity and the target buffer level and receiving the first portion of the media content. Additional embodiments include determining a current buffer level and receiving a second estimated bandwidth capacity of the communication network. Also, embodiments include requesting a second portion of the media content according to the current buffer level and the second estimated bandwidth capacity. Other embodiments are disclosed.

Abstract: A system includes an electronic device and a sensor to detect sensor data corresponding to the electronic device. The system also includes a machine learning processor that receives the sensor data and generates a model of the electronic device to determine a T squared threshold and a Q threshold using a machine learning algorithm. The machine learning processor also performs a T squared analysis of the electronic device by comparing a T squared value to the T squared threshold, and a Q analysis of the electronic device by comparing a Q value to the Q threshold. The machine learning processor also determines that the model is faulty when the T squared value is less than the T squared threshold and the Q value is greater than or equal to the Q threshold, and generates a new model or updates the model when the model is determined to be faulty.

Abstract: Advantageous instruments, assemblies and methods are provided for undertaking imaging techniques (e.g., microscopic imaging techniques). The present disclosure provides improved imaging techniques, equipment and systems. More particularly, the present disclosure provides advantageous microscopy/imaging assemblies with rapid sample auto-focusing (e.g., microscopy/imaging assemblies having instant focusing for rapid sample imaging with auto-focusing). The present disclosure provides for high-throughput whole slide imaging with instant focal plane detection. A whole slide imaging platform/assembly that uses instant focusing systems/methods for high-speed sample autofocusing is provided. Such exemplary platforms/assemblies can be used for digital pathology or the like, and can provide improved, faster and cheaper diagnosis/prognosis of ailments/diseases.

Abstract: A wearable 3D augmented reality display and method, which may include 3D integral imaging optics.

Abstract: Disclosed is a method to color tune an electrochromic device by the use of a standard dye. By following the “subtractive color mixing” theory and selecting the appropriate standard dye to compliment or accentuate the electrochromic material, tuning of the optical and colorimetric properties of the resulting electrochromic device can be achieved. The method can also be used to prepare electrochromic devices that will switch between two neutral colors.

Abstract: Systems and methods for integrating ultra-fast programmable networks in microgrid are disclosed to provide flexible and easy-to-manage communication solutions, thus enabling resilient microgrid operations in face of various cyber and physical disturbances. The system is configured to establish a novel software-defined networking (SDN) based communication architecture which abstracts the network infrastructure from the upper-level applications to significantly expedite the development of microgrid applications, develop three functions of the SDN controller for microgrid emergency operations, including time delay guarantee, failover reconfiguration and rate limit and create a hardware-in-the-loop cyber-physical platform for evaluating and validating the performance of the presented architecture and control techniques.

Abstract: Disclosed herein is a sensor comprising a conduit; the conduit comprising an organic polymer; a working electrode; the working electrode being etched and decorated with a nanostructured material; a reference electrode; and a counter electrode; the working electrode, the reference electrode and the counter electrode being disposed in the conduit; the working electrode, the reference electrode and the counter electrode being separated from each other by an electrically insulating material; and wherein a cross-sectional area of the conduit that comprises a section of the working electrode, a section of the reference electrode and a section of the counter electrode is exposed to detect analytes.

Abstract: The present invention provides gradient porous scaffolds for bone regeneration and osteochondral defect repair, methods for making such gradient porous scaffolds, and methods for using the gradient porous scaffolds.

Abstract: A semiconductor device that includes an array of imaging cells is provided. Each imaging cell of the array of imaging cells includes an imaging region and first and second charge storage regions. Further, each imaging cell includes first and second quantum dot-in-quantum well (QD-in-QW) structures. The first QD-in-QW structure absorbs an incident electromagnetic radiation having a wavelength within a predetermined first wavelength band and generates a hole photocurrent. The second QD-in-QW structure absorbs an incident electromagnetic radiation having a wavelength within a predetermined second wavelength band and generates an electron photocurrent. Each imaging cell further includes p-type and n-type modulation doped QW structures that defines first and second buried QW channels. The first and second buried QW channels provide for lateral transfer of the hole and electron photocurrents for charge accumulation in the first and second charge storage regions, respectively.

Abstract: Disclosed herein is a device that functions as a glucose sensor. The device has a reference electrode; a counter electrode, a working electrode; an electrically conducting membrane; an enzyme layer; a semi-permeable membrane; a first layer of a first hydrogel in operative communication with the working electrode; the first layer of the first hydrogel being operative to store oxygen; wherein the amount of stored oxygen is proportional to the number of freeze-thaw cycles that the hydrogel is subjected to; and a second layer of the second hydrogel. Disclosed too is a method that comprises using periodically biased amperometry towards interrogation of implantable glucose sensors to improve both sensor's sensitivity and linearity while at the same time enable internal calibration against sensor drifts that originate from changes in either electrode activity or membrane permeability as a result of fouling, calcification and/or fibrosis.

Abstract: A method and corresponding apparatus employ a time-varying spectral analysis approach for reconstructing a heart-related signal that includes motion artifacts. The motion artifacts are produced by motion of a biomedical sensor relative to a sensing location. By comparing time-varying spectra of the heart-related signal and a motion signal, those frequency peaks resulting from the motion artifacts may be suppressed in a time-varying spectrum of the heart-related signal. The time-varying spectral analysis based approach enables the heart-related signal to be reconstructed with accuracy by suppressing the motion artifacts. Example applications for the method and corresponding apparatus include training aids (e.g., runners' heart-rate monitors) and hospital patient heart-rate monitors.

Abstract: A method to fractionate and isolate components of oxidized graphene material is provided that includes fractionating a system that includes graphene oxide, a solvent and water, wherein the fractionation creates two phases or fractions: (i) a water phase or fraction that contains highly oxidized graphene oxide, and (ii) a solvent-in-water emulsion phase or fraction that contains a graphene-based material. The graphene-based material is recovered from the solvent-in-water phase or fraction. Fractionation of the solvent-in-water emulsion phase or fraction may be repeated. The graphene-based material (uGO) may be used in a range of applications, e.g., a medical device, a nanoelectronic, an electromechanical system, a sensor, a composite, a catalysis, and energy storage device, and an optics application.

Abstract: Disclosed herein are stable and versatile protein nanoparticles having a range of tunable fluorescent properties. Such nanoparticles may find utility in biological imaging. Methods of synthesis of such nanoparticles are also disclosed.

Abstract: Artificial salivary gland devices and assemblies are provided. The present disclosure provides artificial salivary pump/gland devices and assemblies, and related methods of use. One embodiment utilizes the interstitial/marrow fluid reservoir within the underlying mandibular or maxillary bone as a source for replacement saliva. The salivary pump/assembly, which is implantable in the mandibular or maxillary bone as a dental implant and driven by incidental tooth contact and masticatory forces, harvests interstitial/marrow fluid and treats it via semi-permeable membrane technology and soluble particles as a continuously available saliva replacement. Masticatory forces and tooth contact power the pump to both harvest interstitial/marrow fluid and drive flow through a bed of ion-exchange resins and/or soluble particles to adjust fluid chemistry providing a continuously available saliva-like solution.

Abstract: The present disclosure provides improved sensor assemblies for gases. More particularly, the present disclosure provides for gas sensor assemblies operating at high temperature. Improved high temperature sensor assemblies for reducing gas are provided. In some embodiments, the present disclosure provides advantageous impedancemetric high temperature gas sensor assemblies based on electrospun nanofibers and having selectivity towards reducing gas, and related methods of use. In exemplary embodiments, the present disclosure provides for impedancemetric high temperature gas sensor assemblies having selectivity towards reducing gas. In certain embodiments, the sensor assembly includes electrospun nanofibers. Impedancemetric techniques have been employed at high operating frequency (e.g., 105 Hz) for the first time to provide real-time assemblies, methods and devices to sensitively and/or selectively detect reducing gas (e.g., CO, C3H8 (propane), etc.) at high temperatures (e.g., at about 800° C.).

Abstract: The disclosure provided herein relates generally to mesenchymal-like stem cells “hES-T-MiSC” or “T-MSC” and the method of producing the stem cells. The method comprises culturing embryonic stem cells under conditions that the embryonic stem cells develop through an intermediate differentiation of trophoblasts, and culturing the differentiated trophoblasts to hES-T-MSC or T-MSC, T-MSC derived cells and cell lineages “T-MSC-DL” are also described. Disclosed also herein are solutions and pharmaceutical compositions comprising the T-MSC and/or T-MSC-DL, methods of making the T-MSC and T-MSC-DL, and methods of using the T-MSC and T-MSC-DL for treatment and prevention of diseases, specifically, T-MSC and T-MSC-DL are used as immunosuppressive agents to treat multiple sclerosis and autoimmune diseases.

Abstract: A heat transfer system includes a fuel cell module that produces heat and water, and a thermal energy storage module that stores the heat produced by the fuel cell module. The thermal energy storage module includes a phase-change material. A conduit couples the fuel cell module to the thermal energy storage module. The conduit is oriented to channel the water produced by the fuel cell module through the thermal energy storage module.