Abstract: Artificial salivary gland devices and assemblies are provided. The present disclosure provides artificial salivary pump/gland devices and assemblies, and related methods of use. One embodiment utilizes the interstitial/marrow fluid reservoir within the underlying mandibular or maxillary bone as a source for replacement saliva. The salivary pump/assembly, which is implantable in the mandibular or maxillary bone as a dental implant and driven by incidental tooth contact and masticatory forces, harvests interstitial/marrow fluid and treats it via semi-permeable membrane technology and soluble particles as a continuously available saliva replacement. Masticatory forces and tooth contact power the pump to both harvest interstitial/marrow fluid and drive flow through a bed of ion-exchange resins and/or soluble particles to adjust fluid chemistry providing a continuously available saliva-like solution.

Abstract: A method and corresponding apparatus employ a time-varying spectral analysis approach for reconstructing an electrocardiogram (ECG) signal that includes motion artifacts. The motion artifacts are produced by motion of an ECG sensor relative to a sensing location. The time-varying spectral analysis based approach enables the ECG signal to be reconstructed with accuracy by suppressing the motion artifacts. Example applications for the method and corresponding apparatus include ECG-based heart rate monitoring in wearable devices for fitness tracking and health monitoring even during intense physical activities.

Abstract: A method for oxidizing soot from diesel exhaust gas from a diesel engine. The method involves providing a diesel particulate filter for receiving the diesel exhaust gas; coating a catalyst composition on the diesel particulate filter; and contacting the soot from the diesel exhaust gas with the catalyst coated diesel particulate filter at a temperature sufficient to oxidize the soot to carbon dioxide. The catalyst composition is a doped or undoped manganese oxide octahedral molecular sieve (OMS-2) material. A diesel exhaust gas treatment system that includes a diesel particulate filter for receiving diesel exhaust gas from a diesel engine and collecting soot; and a catalyst composition coated on the diesel particulate filter. The catalyst composition is a doped or undoped manganese oxide octahedral molecular sieve (OMS-2).

Abstract: The present disclosure provides improved films/coatings (e.g., catalyst films/coatings), and improved assemblies/methods for fabricating such films/coatings. More particularly, the present disclosure provides advantageous assemblies/methods for fabricating or synthesizing catalytic material (e.g., catalytic nanostructures) in flame and depositing the catalytic material onto substrates. The present disclosure provides improved catalytic nanostructures, and improved assemblies and methods for their manufacture. In exemplary embodiments, the present disclosure provides for methods/assemblies for synthesizing electrocatalytic nanostructures in flame and depositing such material or catalyst onto different substrates or supports. As such, the present disclosure provides advantageous assemblies that are configured and dimensioned to deposit fully dense, controlled porosity films (e.g., films of metals and oxides or core-shell particles) onto different substrates.

Abstract: A free radical or controlled radical polymerization process of atom or group transfer radical polymerization. The process comprises radically polymerizing one or more radically (co)polymerizable monomers in the presence of a polymerization system. The one or more radically (co)polymerizable monomers comprise at least one or more radically (co)polymerizable diene monomers. The polymerization system comprises: an initiator having one or more radically transferable atoms or groups; a transition metal-ligand complex catalyst, wherein the ligand comprises any C-, N-, O-, P- or S-containing ligand which coordinates with the transition metal; an optional reducing agent capable of regenerating the lower oxidation state of the transition metal catalyst; and an optional organic solvent or water capable of solubilizing the transition metal-ligand complex catalyst. (Co)polymers produced by the free radical or controlled radical polymerization process of atom or group transfer radical polymerization.

Abstract: Improved sensor assemblies are provided. More particularly, the present disclosure provides microelectrode array (“MEA”) real-time in situ global sensing assemblies for enhancing efficiency and stability of wastewater treatment systems. In general, the present disclosure provides for a novel global sensing technology utilizing a microelectrode array (MEA) to solve various problems of monitoring wastewater treatment systems. The present disclosure provides for improved systems/methods for monitoring wastewater treatment systems, with the improved systems/methods obtaining a substantially complete global profile of multiple parameters simultaneously. More particularly, the present disclosure provides that by patterning multiple electrodes (e.g., mm-sized electrodes) on a film (e.g.

Abstract: A metal oxide nanorod array structure according to embodiments disclosed herein includes a monolithic substrate having a surface and multiple channels, an interface layer bonded to the surface of the substrate, and a metal oxide nanorod array coupled to the substrate surface via the interface layer. The metal oxide can include ceria, zinc oxide, tin oxide, alumina, zirconia, cobalt oxide, and gallium oxide. The substrate can include a glass substrate, a plastic substrate, a silicon substrate, a ceramic monolith, and a stainless steel monolith. The ceramic can include cordierite, alumina, tin oxide, and titania. The nanorod array structure can include a perovskite shell, such as a lanthanum-based transition metal oxide, or a metal oxide shell, such as ceria, zinc oxide, tin oxide, alumina, zirconia, cobalt oxide, and gallium oxide, or a coating of metal particles, such as platinum, gold, palladium, rhodium, and ruthenium, over each metal oxide nanorod.

Abstract: Advantageous dental analogs for dental restorations and related methods of use are provided. The present disclosure provides improved analog members for use in fabricating dental implant-supported restorations, and related methods of use. More particularly, the present disclosure provides advantageous systems/methods for the design and use of protection analog members configured to protect cuff portions of coping members during the fabrication of dental restorations. The improved analog members include an added vertical rim or collar to contact and/or protect the cuff portion of coping members when an end of the analog member is screwed/mounted into place into an end of the coping member. This way, the resin added during fabrication will not contact/adhere to the cuff portion allowing a proper seating of the finished fixed implant-supported prosthesis. Use of the improved analog member also can eliminate scratches/damage to the cuff portion (e.g., during trimming and polishing).

Abstract: Disclosed herein are analogues of itraconazole that are both angiogenesis and hedgehog signaling pathway inhibitors. The compounds are expected to be useful in the treatment of cancer, particularly cancers that are dependent upon the hedgehog signaling pathway such as basal cell carcinoma and medulloblastoma.

Abstract: Methods and systems of optimizing efficiency of a motor drive or generator are provided. The methods include measuring data corresponding to input power and output power of a motor drive or generator at a control parameter and different load values. The methods include generating a three-dimensional surface model based on the measured data. The three-dimensional surface model can estimate an efficiency of the motor drive or generator at the control parameter and at unmeasured load values. The methods can include determining optimal efficiency of the motor drive or generator at the different load values and the unmeasured load values based on the three-dimensional surface model.

Abstract: In one aspect, the present disclosure provides a method including rotating a rotatable surface with an object positioned thereon to a plurality of angular positions. The method also includes capturing, via an x-ray microtomography device at each of the plurality of angular positions, a tomograph of the object. The method also includes summing each tomograph of the object to create a three-dimensional image of the object. The method also includes using an additive manufacturing machine to create a three-dimensional replica of the object using the three-dimensional image of the object.

Abstract: The role of a specific E2 region containing a putative fusion peptide (FP) sequence was evaluated. FPs critically contribute to the interaction between proteins and the membrane system of the host cell. Reverse genetics utilizing a full-length infectious clone of the highly virulent CSFV strain Brescia (BICv) was used to evaluate how amino acid substitutions within this region of E2 may affect replication of BICv in cell cultures and affect virus virulence in swine. Interestingly, mutated virus FPi.c was completely attenuated when inoculated intranasally at a dose of 105 TCID50 in swine. Importantly, animals infected with FPi.c virus were protected against the virulent challenge with Brescia virus at 3 and 28 days after vaccination. Protection was evidenced by absence of clinical signs related with CSF as well as the absence of viremia produced by the challenge virulent virus.

Abstract: In one aspect, the present disclosure provides a system for Fourier ptychographic microscopy, the system comprising (i) an image capture apparatus including an objective lens, (ii) at least one processor, and (iii) data storage including program instructions stored thereon that when executed by the at least one processor, cause the system to: (a) capture, via the image capture apparatus, a plurality of initial images of an object, wherein each of the plurality of initial images of the object have a first resolution, and (b) process each of the plurality of initial images in Fourier space to generate a final image of the object having a second resolution, wherein the second resolution is greater than the first resolution.

Abstract: Systems and methods for integrating ultra-fast programmable networks in microgrid are disclosed to provide flexible and easy-to-manage communication solutions, thus enabling resilient microgrid operations in face of various cyber and physical disturbances. The system is configured to establish a novel software-defined networking (SDN) based communication architecture which abstracts the network infrastructure from the upper-level applications to significantly expedite the development of microgrid applications, develop three functions of the SDN controller for microgrid emergency operations, including time delay guarantee, failover reconfiguration and rate limit and create a hardware-in-the-loop cyber-physical platform for evaluating and validating the performance of the presented architecture and control techniques.

Abstract: A mesoporous metal doped cerium oxide catalyst is provided. The catalyst can contain nanotextured cerium oxide (CeO2) which can be utilized for hydrogen production or reformate gas purification in a water gas shift reaction. The catalyst may be advantageously used to remove CO from a gas containing CO. The catalyst may also be incorporated into a fuel processor.

Abstract: African swine fever virus (ASFV) is the etiological agent of a contagious, often lethal viral disease of domestic pigs. The control of African Swine Fever (ASF) has been hampered by the unavailability of vaccines. Experimental vaccines have been derived from naturally occurring, cell culture-adapted, or genetically modified live attenuated ASFVs; however, these vaccines are only successful when protecting against homologous viruses. We have constructed a recombinant ?9GL/?UK virus derived from the highly virulent ASFV Georgia 2007 (ASFV-G) isolate by deleting the specific virulence-associated 9GL (B119L) and the UK (DP96R) genes. In vivo, ASFV-G ?9GL/?UK administered intramuscularly to swine even at relatively high doses (106 HAD50) does not induce disease. Importantly, animals infected with 104 or 106 HAD50 are solidly protected against the presentation of clinical disease when challenged at 28 days post infection with the virulent parental strain Georgia 2007.

Abstract: A semiconductor device is provided that includes an array of imaging cells realized from a plurality of layers formed on a substrate, wherein the plurality of layers includes at least one modulation doped quantum well structure spaced from at least one quantum dot structure. Each respective imaging cell includes an imaging region spaced from a corresponding charge storage region. The at least one quantum dot structure of the imaging region generates photocurrent arising from absorption of incident electromagnetic radiation. The at least one modulation doped quantum well structure defines a buried channel for lateral transfer of the photocurrent for charge accumulation in the charge storage region and output therefrom. The at least one modulation doped quantum well structure and the at least one quantum dot structure of each imaging cell can be disposed within a resonant cavity that receives the incident electromagnetic radiation or below a structured metal film having a periodic array of holes.

Abstract: The compositions and methods described herein relate generally to substituted tropolone derivatives, which, among other features, are useful as histone deacetylase (HDAC) inhibitors.

Abstract: The invention provides methods and cells for improved transplantation of donor transplants to subjects in need thereof.

Abstract: A new and distinct Aronia cultivar named ‘UCONNAM165’ is disclosed, characterized by a compact, dense plants maturing to approximately 2 feet tall and 3 to 4 feet wide. Foliage is uniquely small and very shiny, emerging with a red tinge, green throughout the Spring and Summer, turning red and orange in the Fall. Plants are very useful for landscape, with a short, controlled growth and tolerating a wide range of soil conditions. Profuse flowering. The new variety is a Aronia, normally produced as an outdoor garden or container plant.