Patents Assigned to The University of Melbourne
  • DENTAL MINERALIZATION
    Publication number: 20140147512
    Abstract: A method is provided for mineralizing a dental surface or subsurface including contacting the dental surface with a protein disrupting agent and stabilized amorphous calcium phosphate (ACP) or amorphous calcium fluoride phosphate (ACFP).
    Type: Application
    Filed: January 29, 2014
    Publication date: May 29, 2014
    Applicant: The University of Melbourne
    Inventor: Eric Charles REYNOLDS
  • ELECTRODE AND A FEEDTHROUGH FOR MEDICAL DEVICE APPLICATIONS
    Publication number: 20140094885
    Abstract: The present disclosure provides an electrode and an feedthrough for an implantable medical device. In one embodiment, the implantable electrode and the implantable feedthrough both comprise electrically insulating diamond material and electrically conductive diamond material that form an interface. Further, the present disclosure provides method for fabricating the implantable electrode and the feedthrough.
    Type: Application
    Filed: December 3, 2013
    Publication date: April 3, 2014
    Applicants: National ICT Australia Limited, The University of Melbourne
    Inventors: Hamish Meffin, Kate Fox, David Garrett, Kumaravelu Ganesan, Steven Prawer, Samantha Lichter, Igor Aharonovich
  • STABILIZED CALCIUM PHOSPHATE COMPLEXES
    Publication number: 20140079650
    Abstract: The present invention relates to a phosphopeptide-stabilized amorphous calcium phosphate and/or amorphous calcium fluoride phosphate complex, wherein the complex is formed at a pH of below 7.0. Methods of making such complexes are also provided. The complexes are useful in dental applications, in particular in dental remineralisation.
    Type: Application
    Filed: November 12, 2013
    Publication date: March 20, 2014
    Applicant: The University of Melbourne
    Inventor: Eric Charles REYNOLDS
  • Dental mineralization
    Patent number: 8673363
    Abstract: A method is provided for mineralizing a dental surface or subsurface including contacting the dental surface with a protein disrupting agent and stabilized amorphous calcium phosphate (ACP) or amorphous calcium fluoride phosphate (ACFP).
    Type: Grant
    Filed: June 7, 2006
    Date of Patent: March 18, 2014
    Assignee: The University of Melbourne
    Inventor: Eric Charles Reynolds
  • IONIC COMPLEXES
    Publication number: 20140056824
    Abstract: The present invention provides a phosphopeptide or phosphoprotein (PP) stabilised amorphous calcium phosphate or amorphous calcium fluoride phosphate complex having a calcium ion greater than about 30 moles of calcium per mole of PP.
    Type: Application
    Filed: November 7, 2013
    Publication date: February 27, 2014
    Applicant: The University of Melbourne
    Inventor: Eric Charles REYNOLDS
  • CONTINUOUS PROCESS FOR THE FUNCTIONALIZATION OF FULLERENES
    Publication number: 20140046089
    Abstract: A continuous process for the functionalization of fullerenes is disclosed. The process offers numerous advantages in comparison to traditional batch processes. The functionalized fullerenes may find use in the fabrication of hetero-junction devices.
    Type: Application
    Filed: December 21, 2011
    Publication date: February 13, 2014
    Applicant: The University of Melbourne
    Inventors: David Jones, Wing Ho Wallace Wong, Andrew Holmes, Helga Seyler
  • Methods of treating mammals with eustachian tube dysfunctions
    Patent number: 8642631
    Abstract: The invention relates to methods of medically treating mammals with Eustachian tube dysfunctions, such as Ménière's disease, vertigo, Otitis Media (including Otitis Media with Effusion (OME), Acute Otitis Media (AOM) and Aerotitis Media (AM)) as well as other disorders which are characterized by ET dysfunction.
    Type: Grant
    Filed: May 27, 2009
    Date of Patent: February 4, 2014
    Assignee: University of Melbourne
    Inventors: Colin Russell Anderson, Burkhard Franz
  • polypeptides and nucleotides
    Patent number: 8642731
    Abstract: The present invention relates to isolated Porphyromonas gingivalis polypeptides and nucleotides. The polypeptides include an amino acid sequence selected from the group consisting of: SEQ. ID. NO. 110; SEQ. ID. NO. 111; SEQ. ID. NO. 112; SEQ. ID. NO. 113; SEQ ID NO: 120; SEQ. ID. NO. 123; SEQ. ID. NO. 124; SEQ. ID. NO. 125; SEQ. ID. NO. 130; SEQ. ID. NO. 131; SEQ. ID. NO. 132; SEQ. ID. NO. 133; SEQ. ID. NO. 135; SEQ. ID. NO. 136; SEQ. ID. NO. 137; SEQ. ID. NO. 138; SEQ. ID. NO. 143; SEQ. ID. NO. 144; SEQ. ID. NO. 145; SEQ. ID. NO. 146; SEQ. ID. NO. 147; SEQ. ID. NO. 148; and amino acid sequences at least 95% identical thereto.
    Type: Grant
    Filed: February 21, 2012
    Date of Patent: February 4, 2014
    Assignees: CSL Limited, The University of Melbourne
    Inventors: Bruce C. Ross, Ian G. Barr, Michelle A. Patterson, Catherine T. Agius, Linda J. Rothel, Mai B. Margetts, Dianna M. Hocking, Elizabeth A. Webb
  • Analyte detection assay
    Patent number: 8617824
    Abstract: A rapid and sensitive analyte detection assay is based on whispering gallery modes of fluorescently labelled microspheroidal particles. Ligands for the analyte, such as nucleic acids, are anchored to the particles. The fluorescent labels may comprise fluorophores or quantum dots. In the latter case, the particles may comprise melamine formaldehyde. The assay may be used to detect analytes in aqueous samples.
    Type: Grant
    Filed: November 20, 2009
    Date of Patent: December 31, 2013
    Assignees: Genera Biosystems Limited, The University of Melbourne
    Inventors: Karl Frederick Poetter, Edin Nuhiji, Paul Mulvaney
  • Stabilized calcium phosphate complexes
    Patent number: 8609071
    Abstract: The present invention relates to a phosphopeptide-stabilized amorphous calcium phosphate and/or amorphous calcium fluoride phosphate complex, wherein the complex is formed at a pH of below 7.0. Methods of making such complexes are also provided. The complexes are useful in dental applications, in particular in dental remineralization.
    Type: Grant
    Filed: November 24, 2005
    Date of Patent: December 17, 2013
    Assignee: The University of Melbourne
    Inventor: Eric Charles Reynolds
  • Ionic complexes
    Patent number: 8603988
    Abstract: The present invention provides a phosphopeptide or phosphoprotein (PP) stabilized amorphous calcium phosphate or amorphous calcium fluoride phosphate complex having a calcium ion greater than about 30 moles of calcium per mole of PP.
    Type: Grant
    Filed: June 23, 2006
    Date of Patent: December 10, 2013
    Assignee: The University of Melbourne
    Inventor: Eric Charles Reynolds
  • SYNTHETIC PEPTIDE CONSTRUCTS FOR THE DIAGNOSIS AND TREATMENT OF PERIODONTIS ASSOCIATED WITH PORPHYROMONAS GINGIVALIS
    Publication number: 20130309179
    Abstract: The present invention relates to an oral composition and an immunogenic composition for the suppression of the pathogenic effects of the intra-oral bacterium Porphyromonas gingivalis associated with periodontal disease.
    Type: Application
    Filed: March 28, 2013
    Publication date: November 21, 2013
    Applicant: The University of Melbourne
    Inventors: Eric Charles Reynolds, Neil Martin O'BRIEN-SIMPSON, Nada SLAKESKI
  • Pain treatment
    Publication number: 20130243791
    Abstract: The present invention relates generally to a method for the treatment and prophylaxis of pain. In accordance with the present invention, it is proposed that antagonists of GM-CSF are effective in the treatment of pain. Antagonists of GM-CSF include, but are not limited to, antibodies which are specific for GM-CSF or the GM-CSF receptor. The present invention further provides transgenic animals, such as a GM-CSF knock-out mouse, useful for testing antagonists in certain disease models.
    Type: Application
    Filed: May 28, 2013
    Publication date: September 19, 2013
    Applicant: The University of Melbourne
    Inventors: John Allan Hamilton, Andrew David Cook
  • Non-steroidal compounds
    Patent number: 8536157
    Abstract: The present invention relates to non-steroidal compounds useful in the treatment of inflammatory conditions and pharmaceutical compositions comprising them.
    Type: Grant
    Filed: April 14, 2008
    Date of Patent: September 17, 2013
    Assignee: The University of Melbourne
    Inventors: Alastair Stewart, Martin Banwell, Brenda Leung, Anu Augustine, Jacki Kitching, Thomasz Bilski
  • NOVEL IMMUNOSTIMULATORY METHOD
    Publication number: 20130230544
    Abstract: This invention relates to a method for treating or preventing a disease by raising an innate immune response in a subject, the method comprising administering to the subject an effective amount of a composition comprising a TLR2 moiety in solution, wherein the TLR2 moiety comprises a TLR2 agonist and wherein the disease is not treated or prevented by a humoral or cellular immune response directed against the TLR2 moiety.
    Type: Application
    Filed: September 22, 2011
    Publication date: September 5, 2013
    Applicant: THE UNIVERSITY OF MELBOURNE
    Inventors: David Charles Jackson, Amabel Tan, Weiguang Zeng
  • Temperature sensitive vaccine strain of and uses thereof
    Patent number: 8524252
    Abstract: The present invention relates to a Mycoplasma hyopneumoniae vaccine strain comprising a mutation in at least one of the genes listed or as deposited with the National Measurements Institute (Australia) under accession number NM04/41259, which strain is temperature sensitive and attenuated, a vaccine comprising such strains and methods and uses thereof.
    Type: Grant
    Filed: May 19, 2010
    Date of Patent: September 3, 2013
    Assignees: Bioproperties Pty Ltd., The University of Melbourne
    Inventors: Rima Youil, Youssef Abs El-Osta, Glenn Browning, Phillip Markham
  • Process for the preparation of a cross-linked multilayer film
    Patent number: 8496997
    Abstract: The present invention provides a process for the preparation of a multilayer film, in particular, a cross-linked multilayer macromolecular film.
    Type: Grant
    Filed: March 10, 2011
    Date of Patent: July 30, 2013
    Assignee: The University of Melbourne
    Inventors: Francesco Caruso, Greg Guanghua Qiao, Anton Richard Blencowe, Tor Kit Goh, Luke Andrew Connal, Georgina Kate Such
  • SYNTHETIC IMMUNOGEN USEFUL FOR GENERATING LONG LASTING IMMUNITY AND PROTECTION AGAINST PATHOGENS
    Publication number: 20130183377
    Abstract: The present invention relates to a synthetic immunogen represented by the general formula 1, useful for generating long lasting protective immunity against various intracellular pathogens which are the causative agents of tuberculosis, leishmaniasis, AIDS, trypanosomiasis, malaria and also allergy, cancer and a process for the preparation thereof. The developed immunogen is able to circumvent HLA restriction in humans and livestock. The invention further relates to a vaccine comprising the said immunogen for generating enduring protective immunity against various diseases. The said vaccine is targeted against intracellular pathogens, more particularly the pathogen M. tuberculosis in this case. In the present invention, promiscuous peptides of M. tuberculosis are conjugated to TLR ligands especially; Pam2Cys to target them mainly to dendritic cells and therefore elicit long-lasting protective immunity.
    Type: Application
    Filed: September 14, 2011
    Publication date: July 18, 2013
    Applicants: UNIVERSITY OF MELBOURNE, COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH
    Inventors: Javed Naim Agrewala, Uthaman Gowthaman, David Jackson, Weiguang Zeng
  • Method of treating pain using an antagonist of GM-CSF
    Patent number: 8475796
    Abstract: The present invention relates generally to a method for the treatment and prophylaxis of pain. In accordance with the present invention, it is proposed that antagonists of GM-CSF are effective in the treatment of pain. Antagonists of GM-CSF include, but are not limited to, antibodies which are specific for GM-CSF or the GM-CSF receptor. The present invention further provides transgenic animals, such as a GM-CSF knock-out mouse, useful for testing antagonists in certain disease models.
    Type: Grant
    Filed: December 21, 2009
    Date of Patent: July 2, 2013
    Assignee: University of Melbourne
    Inventors: John Allan Hamilton, Andrew David Cook
  • Synthetic peptide constructs for the diagnosis and treatment of Periodontitis associated with
    Patent number: 8431688
    Abstract: The present invention relates to an oral composition and an immunogenic composition for the suppression of the pathogenic effects of the intra-oral bacterium Porphyromonas gingivalis associated with periodontal disease.
    Type: Grant
    Filed: June 9, 2010
    Date of Patent: April 30, 2013
    Assignee: The University of Melbourne
    Inventors: Eric C. Reynolds, Neil Martin O'Brien-Simpson, Nada Slakeski