Patents Assigned to The University of North Texas
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Patent number: 11542394Abstract: Microlaser based dye doped polymeric resonators are provided as well as pharmaceutical formulations containing the microlaser based dye doped polymeric resonators, methods of making thereof, and methods of use thereof for monitoring and/or stimulating electrical activity in a brain of a subject in need thereof. The microlaser based dye doped polymeric resonators can include a particle having a spherical core containing one or more fluorescent dyes dispersed within a polymer matrix, wherein the polymer matrix has an index of refraction of about 1.2 or greater; an outer surface surrounding the spherical core; and a gold nanoparticle, wherein the gold nanoparticle is on the outer surface, is dispersed within the spherical core, or both. The fluorescent dyes can include a voltage sensitive fluorescent dye.Type: GrantFiled: August 26, 2019Date of Patent: January 3, 2023Assignee: UNIVERSITY OF NORTH TEXASInventor: Maurizio Manzo
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Patent number: 11525834Abstract: The present invention includes methods and kits for the diagnosing a neurological disease within primary care settings comprising: obtaining a blood test sample from a subject, measuring IL-7 and TNF? biomarkers in the blood sample, comparing the level of the one or a combination of biomarkers and neurocognitive screening tests with the level of a corresponding one or combination of biomarkers in a normal blood sample and neurocognitive screening tests, and predicting that an increase in the level of the blood test sample in relation to that of the normal blood sample indicates that the subject is likely to have a neurological disease.Type: GrantFiled: July 9, 2014Date of Patent: December 13, 2022Assignees: University of North Texas Health Science Center at Fort Worth, Board of Regents, The University of Texas SystemInventors: Sid E. O'Bryant, Robert C. Barber, Guanghua Xiao, Dwight German
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Publication number: 20220290171Abstract: Disruption of a Lipid Droplet Regulatory—Tudor Domain Containing (LRT1) gene in plants leads to accumulation of storage lipids in cells of the plants. An increased amount of lipids storage in these plants offers new possibilities for developing crops with more energy dense biomass and increased seed oil content.Type: ApplicationFiled: February 23, 2022Publication date: September 15, 2022Applicant: University of North TexasInventors: Kent Chapman, Ann Price, Kevin Mutore
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Patent number: 11415555Abstract: Aspects of ultrasonic through-wall data communication are described. In some aspects, a sensor device is located in an isolated environment behind a wall. A modulator generates a modulated sensor signal based on the binary sensor signal and a carrier signal. A coaxially aligned pair of electroacoustic transducers that transmits the modulated sensor signal through the wall of the isolated environment. A demodulator demodulates the modulated sensor signal to generate a demodulated binary sensor signal. A sensor data recovery component converts the demodulated binary sensor signal into an image or another sensor parameter.Type: GrantFiled: June 29, 2020Date of Patent: August 16, 2022Assignee: UNIVERSITY OF NORTH TEXASInventor: Haifeng Zhang
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Publication number: 20220233479Abstract: Certain embodiments are directed to methods of treating or preventing an addictive behavior in a subject, said method comprising administering to said subject an effective amount of a DMTU or a composition comprising same.Type: ApplicationFiled: July 17, 2020Publication date: July 28, 2022Applicant: UNIVERSITY OF NORTH TEXAS HEALTH SCIENCE CENTERInventors: Michael J. FORSTER, Ritu A. SHETTY, Jacques NGUYEN, Liang-Jun YAN
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Publication number: 20220211523Abstract: A dimpled stent design has geometrical characteristics, namely dimple width and depth, which generate dimple site specific turbulence and thrust within the blood flow to reduce or eliminate restenosis. The dimpled stent design is produced by laser processing of the stent material to produce different sizes, which may be predicted by a Multiphysics computational model, placements, and spatial layouts of dimples in the stent.Type: ApplicationFiled: March 21, 2022Publication date: July 7, 2022Applicant: University of North TexasInventors: Narendra Dahotre, Jewon Sohn, Sameehan S. Joshi
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Patent number: 11357282Abstract: A system for measuring and controlling foot temperature. The system comprises a heating or cooling device including one or more sealed fluidic pathways having a cooling or heating fluid therein and disposed in or on an article of footwear or a sock. A pumping device coupled to the heating or cooling device is configured to circulate the fluid in the one or more sealed fluidic pathways. A heat exchanger coupled to the heating or cooling device is configured to remove or add heat from or to the fluid in the one or more sealed fluidic pathways. A controller coupled to the pumping device and the heat exchanger is configured to control the pumping device and the heat exchanger to cool or heat a foot located inside the article of footwear or the sock.Type: GrantFiled: November 30, 2018Date of Patent: June 14, 2022Assignees: Vivonics, Inc., University of North Texas Health Science CenterInventors: Ian Cohen, Gordon B. Hirschman, Anna M Galea, Hsiang-Wei Ma, Metin Yavuz, Linda Adams, Ali Ersen
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Patent number: 11355739Abstract: The present application relates to methods for depositing two-dimensional materials (e.g., MoS2, WS2, MoTe2, MoSe2, WSe2, BN, BN—C composite, and the like) onto lithium electrodes. Battery systems incorporating lithium metal electrodes coated with two-dimensional materials are also described. Methods may include intercalating the two-dimensional materials to facilitate flow of Lithium ions in and out of the lithium electrode. Two-dimensional material coated lithium electrodes provide for high cycling stability and significant performance improvements. Systems and methods further provide electrodes having carbon structures (e.g., carbon nanotubes (CNTs), graphene, porous carbon, free-standing 3D CNTs, etc.) with sulfur coatings.Type: GrantFiled: February 9, 2018Date of Patent: June 7, 2022Assignee: University of North TexasInventors: Wonbong Choi, Eunho Cha
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Patent number: 11352783Abstract: A method of making an insulated material comprises melting a phase change material to form liquid phase change material, combining the liquid phase change material with an insulating material, and forming a composite insulation material in response to the combining. The insulating material can be a porous material that comprises a plurality of pores, and the liquid phase change material is disposed in the plurality of pores. The phase change material can also be stored in a container and used as layer in an insulation system.Type: GrantFiled: January 28, 2020Date of Patent: June 7, 2022Assignee: UNIVERSITY OF NORTH TEXASInventors: Sheldon Q. Shi, Weihuan Zhao, Liping Cai
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Patent number: 11287407Abstract: The present invention includes an apparatus and method for detecting the location of one or more sources of one or more target molecule, the apparatus comprising: a molecule detector; and a processor connected to the molecule detector and to a global position system, wherein the processor calculates the presence of the one or more target molecules, runs a computer code that determines a dynamic reverse gas stack model for the one or more target molecules, and triangulates the possible position for a source or effluent of the one or more target molecules based on the dynamic reverse gas stack model. The determined reverse gas stack model may have a Gaussian dispersion over one or more sampled locations.Type: GrantFiled: October 12, 2016Date of Patent: March 29, 2022Assignee: University of North TexasInventor: Guido Fridolin Verbeck, IV
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Publication number: 20220073503Abstract: In some aspects, the present disclosure provides compounds of the formulae: (A), (B), (III), and/or (IV), wherein the variables are as defined herein. Pharmaceutical compositions of the compounds are also provided. In some aspects, the compounds or compositions of the present disclosure may be used for the treatment of diseases or disorders, such as eye diseases and peripheral arterial diseases such as hind limb ischemia.Type: ApplicationFiled: December 20, 2019Publication date: March 10, 2022Applicant: University of North Texas Health Science CenterInventor: Suchismita ACHARYA
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Patent number: 11260468Abstract: A friction stir welding tool comprises a cylindrical shank, a shoulder portion disposed at a distal end of the shank, a pin extending from the shoulder, a cutting insert mounted within a concave portion at the distal end of the shank, and a scribe cutter mounted at a distal end of the cutting insert. The cutting insert extends distally through a channel in the pine, and the scribe cutter extends from a distal end surface of the pin in an offset position. The distal end surface of the pin is perpendicular to a longitudinal axis of the shank.Type: GrantFiled: July 10, 2020Date of Patent: March 1, 2022Assignee: University of North TexasInventors: Michael Frank, Tianhao Wang, Rajiv Mishra
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Patent number: 11261477Abstract: In alternative embodiments, provided are methods for the glycosylation modification of bioactive compounds and drugs using isolated, recombinant or genetically modified uridine diphosphate glycosyl-transferases (UGTs). In alternative embodiments, provided are methods for modifying UGTs to generate recombinant UGTs with altered donor and/or acceptor specificities. In alternative embodiments, provided are methods for screening for recombinantly engineered UGTs with new or altered properties, for example, for new or altered donor and/or acceptor specificities, where in alternative embodiments the screening comprise use of bacterial, yeast or baculovirus expression system.Type: GrantFiled: July 8, 2020Date of Patent: March 1, 2022Assignee: UNIVERSITY OF NORTH TEXASInventor: Xiaoqiang Wang
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Patent number: 11230711Abstract: The subject invention provides methods of treating neurological disease or disorder, such as brain injuries, such as stroke, traumatic brain injury (TBI), or other ischemic events that cause brain injury by inhibiting or down-regulating Let-7i activity or function. The disclosed methods may have the potential to extend the “window of opportunity” for treatment of such injuries and enhance the effectiveness of existing therapeutics.Type: GrantFiled: August 13, 2018Date of Patent: January 25, 2022Assignee: UNIVERSITY OF NORTH TEXAS HEALTH SCIENCE CENTERInventors: Meharvan Singh, Chang Su, Trinh Nguyen
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Publication number: 20220008350Abstract: Certain embodiments are directed to methods for making programmable bioinspired nanoparticles (P-BiNP). Nanoparticles are coated with a cell membrane derived from a cell stimulated to express or overexpress a protein identified as being expressed in a target cell, forming a homotypic and organ targeted nanoparticle delivery vehicle.Type: ApplicationFiled: October 16, 2019Publication date: January 13, 2022Applicant: University of North Texas Health Science CenterInventors: Jamboor K. VISHWANATHA, Andrew GDOWSKI, Amalendu Prakash RANJAN, Anindita MUKERJEE
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Publication number: 20210379621Abstract: The hydrophobic and corrosion resistive film of cross-linked poly(hexafluoroisopropyl methacrylate) was prepared by photopolymerization. The starting materials were a monomer of 1,1,1,3,3,3-hexafluoroisopropyl methacrylate, a photoinitiator of hydroxycyclohexyl phenyl ketone, and a cross-linker of poly(ethyleneglycol diacrylate). Photopolymerization was used to start polymerization and to cure the polymer film on an aluminum surface. Drop-casting was used to deposit the fluoropolymer onto an aluminum substrate (AA 3003). The fluoropolymer film has high corrosion protection when measured by potentiodynamic polarization and open circuit potential techniques in an aqueous solution of 3.5% NaCl. Fourier-transform infrared spectroscopy was used to monitor the polymerization process. The dynamic contact angle technique was used to measure the hydrophobicity for the fluorinated polymer coating. Thermal stability of the fluorinated polymer was measured using thermogravimetric analysis.Type: ApplicationFiled: June 9, 2021Publication date: December 9, 2021Applicant: University of North TexasInventors: Mohammad A. Omary, Teresa D. Golden, Sreekar B. Marpu, Waleed K. Yaseen
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Patent number: 11172731Abstract: Dual-layer insole apparatuses for diabetic foot lesion prevention and related methods are provided. Some insole apparatuses have a body defining a plurality of cavities configured to be coupled to a fluid source. The fluid source can deliver fluid to vary internal pressures of the cavities. The body further defines an insole-shaped structure.Type: GrantFiled: November 28, 2017Date of Patent: November 16, 2021Assignees: The Board of Regents of the Universsity of Texas Systems, The University of North Texas Health Science Center At Fort WorthInventors: Muthu B. J. Wijesundara, Wei Carrigan, Ryan Landrith, Metin Yavuz
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Patent number: 11136525Abstract: Various liquid and semisolid lubricant compositions are provided, in particular lubricant compositions containing oil from the seeds of the Brassicaceae Orychophragmus violaceus, preferably those that have been esterified with one or more fatty acids such as palmitoleic acid, oleic acid, linoleic acid, lauric acid, palmitic acid, stearic acid, or a combination thereof. In various aspects, lubricant compositions are provided that include a petroleum or a synthetic base oil and about 40% or less by weight of a liquid lubricant composition containing oil from the seeds of the Brassicaceae Orychophragmus violaceus, preferably those that have been esterified with one or more fatty acids. In various aspects, semisolid lubricant composition are provided containing an emulsion of (i) a thickener and (ii) an oil from the seeds of the Brassicaceae Orychophragmus violaceus, preferably those that have been esterified with one or more fatty acids.Type: GrantFiled: December 14, 2018Date of Patent: October 5, 2021Assignees: University of North Texas, Board of Regents of the University of Nebraska, Indiana University Research and Technology Corp, Huazhong Agricultural UniversityInventors: Diana Berman, Kent Dean Chapman, Tervor Bradley Romsdahl, Edgar Benjamin Cahoon, Robert Earl Minto, Chunyu Zhang
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Patent number: 11130176Abstract: Embodiments of the present disclosure provide improved techniques for creating SMA materials and SMA powders. SMA materials and powders formed may be used to form porous structures suitable for applications such as biomaterials, damping applications, actuators, and/or sensors. Embodiments for performing hydriding and dehydriding of SMA wires at low pressure and low temperature are provided. Methods may be used to produce a shape memory alloy (SMA) powder. Such methods may include hydriding a length SMA wire under low pressure for a period of time to produce a length of hydrided SMA wire, crushing the length of hydrided SMA wire to form a hydrided SMA powder, and dehydriding the hydrided SMA powder to form a dehydrided SMA powder.Type: GrantFiled: September 29, 2017Date of Patent: September 28, 2021Assignee: University of North TexasInventors: Marcus Lynn Young, Yoav Snirs
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Patent number: 11123713Abstract: Provided herein is a method of preparing a porous composite ceramic material and a porous composite ceramic material made by the method of preparing.Type: GrantFiled: June 25, 2019Date of Patent: September 21, 2021Assignees: UCHICAGO ARGONNE, LLC, UNIVERSITY OF NORTH TEXAS, THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITYInventors: Diana Berman, Elena Shevchenko, Matteo Cargnello, Benjamin Diroll, Emmett Goodman