Patents Assigned to The University of Oregon
  • Patent number: 11113622
    Abstract: Spin qubits are situated in mechanical resonators that are acoustically coupled with acoustic waveguides. The acoustic waveguides provide frequency dependent phonon propagation selected so that mechanical resonators adjacent to a selected mechanical resonator are acoustically coupled to the selected mechanical resonator in different acoustic frequency ranges. This configure permits directional transfer of quantum states between spins in spin-mechanical resonator and provides a scalable platform for spin-based quantum computing.
    Type: Grant
    Filed: March 5, 2019
    Date of Patent: September 7, 2021
    Assignee: University of Oregon
    Inventors: Hailin Wang, Mark C. Kuzyk
  • Patent number: 11099076
    Abstract: A thermo-mechanical resonating microbolometer has a graphene absorber suspended above a metallic silicon substrate to form a mechanical resonator. Microelectronic circuitry electrically connected to the graphene resonator and the metallic silicon substrate drives electronically the motion of the graphene absorber. Shifts in the mechanical resonant frequency of the graphene layer due to the absorption of incident radiation is measured electronically or using optical interferometry. A bolometer sensor array may be fabricated using such graphene microbolometer elements.
    Type: Grant
    Filed: March 8, 2019
    Date of Patent: August 24, 2021
    Assignee: University of Oregon
    Inventors: Benjamin J. Alemán, Andrew D. Blaikie, David J. Miller
  • Patent number: 11078157
    Abstract: Disclosed herein are embodiments of a donor compound that releases H2S by reacting with a reactive compound. The donor compound embodiments described herein can be used to deliver H2S to a subject or a sample and further can be used to administer therapeutic agents. The donor compound embodiments also can facilitate bioconjugation. Methods of making and using the donor compound embodiments also are disclosed.
    Type: Grant
    Filed: January 30, 2019
    Date of Patent: August 3, 2021
    Assignee: University of Oregon
    Inventors: Michael D. Pluth, Matthew M. Cerda
  • Publication number: 20210214368
    Abstract: Disclosed herein are embodiments of a compound that is capable of releasing COS and/or H2S upon reaction with a thiol-containing compound. The compound embodiments also can produce a detectable signal (e.g., a fluorescent signal) substantially concomitantly with COS and/or H2S release and/or can release an active agent, such as a therapeutic agent. Methods of making and using the compound embodiments also are disclosed.
    Type: Application
    Filed: January 30, 2019
    Publication date: July 15, 2021
    Applicant: University of Oregon
    Inventors: Michael D. Pluth, Yu Zhao, Matthew M. Cerda
  • Patent number: 11040942
    Abstract: Disclosed herein are embodiments of a donor compound that releases COS and/or CS2, which can be converted to H2S. The donor compound embodiments described herein can be used to deliver H2S to a subject or a sample and further can be used to administer therapeutic agents. Methods of making and using the donor compound embodiments also are disclosed.
    Type: Grant
    Filed: January 30, 2019
    Date of Patent: June 22, 2021
    Assignee: University of Oregon
    Inventors: Michael D. Pluth, Yu Zhao
  • Patent number: 11038618
    Abstract: A de-multiplexer (1) for separating two co-propagating modes of electromagnetic radiation includes a volume (2) having a path therethrough for receiving electromagnetic radiation, an input (8) for directing two co-propagating modes of electromagnetic radiation to be incident upon the volume, a control source (12) of electromagnetic radiation arranged to generate a time-dependent control field. The volume is arranged and the time-dependent control field is shaped such that, when the two co-propagating modes of electromagnetic radiation and the time-dependent control field are incident upon the volume contemporaneously, the time-dependent control field causes the volume to accept one of the two modes of electromagnetic radiation onto a mode of the volume without any parametric non-linear optical interaction taking place and to reflect or transmit the other of the two modes of electromagnetic radiation, so to spatially and/or temporally separate the two modes of electromagnetic radiation from each other.
    Type: Grant
    Filed: December 11, 2018
    Date of Patent: June 15, 2021
    Assignees: OXFORD UNIVERSITY INNOVATION LIMITED, UNIVERSITY OF OREGON
    Inventors: Michael Raymer, Dylan Saunders, Joshua Nunn, Benjamin Brecht, Ian Walmsley
  • Patent number: 11021489
    Abstract: Disclosed herein are polycyclic aromatic compound embodiments and methods of making and using such compounds. In some embodiments, the polycyclic aromatic compounds comprise an indenoindenodi(benzothiophene) skeleton. The polycyclic aromatic compound embodiments can be used in a variety of devices, such as electronic and/or electrooptical devices.
    Type: Grant
    Filed: February 28, 2020
    Date of Patent: June 1, 2021
    Assignee: University of Oregon
    Inventors: Michael Haley, Justin Dressler, Joshua Barker
  • Patent number: 11021447
    Abstract: A compound, or a protonate or salt thereof, of formula I: wherein Y is aryl, substituted aryl, heteroaryl, or substituted heteroaryl; n is 1 or 2; each R10 is independently alkyl, substituted alkyl, a polyether moiety, carboxyl, substituted carboxyl, alkoxy, substituted alkoxy, haloalkyl, halogen, nitro, amino, aryloxy, aryl, substituted aryl, cyano, hydroxyl, carbonylamino, aminocarbonyl, acyl, sulfonyl, or substituted sulfonyl; a is 0 to 4; is an aryl or heteroaryl ring; and each R is independently halogen, carbonylamino, sulfonamide, carboxylic acid or hydrogen, provided at least one R is a halogen; and provided that if Y is are not respectively.
    Type: Grant
    Filed: May 1, 2019
    Date of Patent: June 1, 2021
    Assignees: University of Oregon, University of Montana
    Inventors: Jessica Lohrman, Darren W. Johnson, Michael M. Haley, Orion B. Berryman, Asia M. Riel, Daniel A. Decato
  • Patent number: 10968432
    Abstract: Methods of identifying compounds that increase ? cell number and/or proliferation by determining the effect of compounds on ? cell number or proliferation in zebrafish pancreas are provided.
    Type: Grant
    Filed: February 6, 2020
    Date of Patent: April 6, 2021
    Assignee: University of Oregon
    Inventors: Jennifer Hampton, Karen Guillemin
  • Publication number: 20210095069
    Abstract: Disclosed herein are embodiments of a nanohoop-functionalized polymer and methods of making and using the same. In particular embodiments, polymer comprises one or more nanohoops that extend from the polymer backbone. Also disclosed herein are polymerizable nanohoop monomer embodiments that can be used to make the polymer embodiments disclosed herein.
    Type: Application
    Filed: September 25, 2020
    Publication date: April 1, 2021
    Applicant: University of Oregon
    Inventors: Ramesh Jasti, Ruth Maust, Penghao Li
  • Patent number: 10934290
    Abstract: Disclosed herein are embodiments of nanostructure compounds that exhibit unique shape configurations, such as nanohoops. The compounds disclosed herein exhibit unique chemical and electrochemical properties that can be tuned and modified to facilitate their use in a variety of different applications.
    Type: Grant
    Filed: June 20, 2016
    Date of Patent: March 2, 2021
    Assignee: University of Oregon
    Inventors: Ramesh Jasti, Evan R. Darzi
  • Publication number: 20210010057
    Abstract: Provided are SpdE polypeptides and variants and nucleic acids encoding the SpdE polypeptides and variants. Also provided are vectors including one or more nucleic acids encoding a SpdE polypeptide or variant and cells including a nucleic acid encoding the SpdE polypeptide or variant, as well as cells expressing a SpdE polypeptide or variant and compositions including such cells and a pharmaceutically acceptable carrier. Finally, methods of detecting presence and/or amount of one or more amino acids in a sample are provided. The methods include contacting the sample with a SpdE protein, measuring diguanylate cyclase activity of the SpdE protein; and comparing the diguanylate cyclase activity of the SpdE protein to a control. The methods can utilize isolated SpdE protein or a cell expressing a SpdE protein.
    Type: Application
    Filed: July 8, 2020
    Publication date: January 14, 2021
    Applicant: University of Oregon
    Inventors: Catherine Robinson, Emily Sweeney, Karen Guillemin
  • Publication number: 20200407708
    Abstract: Compositions and methods for assessing protein function are provided. A modified SpyCatcher protein that can include a tag is provided. Modified SpyCatcher proteins linked to a protein of interest, such as a nuclease are also provided. The methods include contacting a SpyCatcher protein and a SpyTagged protein to form a complex that may further include a protein of interest, one or more nucleic acids, and/or a nuclease. The methods can be used to purify a protein of interest or identify or target a protein binding site in a nucleic acid.
    Type: Application
    Filed: June 24, 2020
    Publication date: December 31, 2020
    Applicant: University of Oregon
    Inventor: Jeffrey McKnight
  • Patent number: 10879445
    Abstract: A quantum emitter device is composed of a hole milled in a layer of hexagonal boron nitride (hBN) on a substrate made of silicon dioxide. The hole preferably has a side wall angle 1.1°±0.28° from the horizontal, has an oval shape with minor axis 516 nm±20 nm and major axis 600 nm±20 nm, and/or has a depth 4 nm±1 nm. The hBN layer preferably has a total thickness of 5-10 nm. The holes may be fabricated using a gallium focused ion beam, a helium focused ion beam, electron beam directed etching, or photolithography and reactive ion etch (RIE) with sidewall tapering.
    Type: Grant
    Filed: February 12, 2020
    Date of Patent: December 29, 2020
    Assignee: University of Oregon
    Inventors: Benjamín J. Alemán, Joshua E. Ziegler
  • Patent number: 10871699
    Abstract: Apparatus include an optical cavity including an optical coupling portion situated to couple an optical signal input field to an intracavity optical signal field and an optical control input field to an intracavity optical control field, wherein the optical cavity includes a nonlinear optical medium that mediates a selective exchange of at least one predetermined temporal mode between the intracavity optical signal field and an intracavity optical register field based on a nonlinear phase-matched interaction between the intracavity optical signal, control, and register fields and selectable field characteristics of the optical control input field.
    Type: Grant
    Filed: August 2, 2019
    Date of Patent: December 22, 2020
    Assignee: University of Oregon
    Inventors: Dileep V. Reddy, Michael G. Raymer
  • Publication number: 20200370188
    Abstract: A bipolar membrane comprising a first member comprising at least one anion exchange material; a second member comprising at least one cation exchange material, wherein the first member and the second member together form an interface junction; and disposed within the interface junction a first layer comprising a first water dissociation catalyst and a second layer comprising a second water dissociation catalyst, wherein the first water dissociation catalyst is different than the second water dissociation catalyst.
    Type: Application
    Filed: March 12, 2020
    Publication date: November 26, 2020
    Applicant: University of Oregon
    Inventors: Sebastian Oener, Shannon W. Boettcher, Marc Foster
  • Publication number: 20200354417
    Abstract: Methods of treating or inhibiting inflammation in a subject include administering an anti-inflammatory protein to the subject. In some embodiments, the protein has at least 80% sequence identity to the amino acid sequence set forth as SEQ ID NO: 1, SEQ ID NO: 17, or fragments thereof. Isolated polypeptides, nucleic acids, and recombinant vectors including a nucleic acid encoding the anti-inflammatory protein (such as a nucleic acid encoding a protein with at least 80% sequence identity to SEQ ID NO: 1, SEQ ID NO: 17, or fragments thereof) operably linked to a heterologous promoter are also disclosed.
    Type: Application
    Filed: July 30, 2020
    Publication date: November 12, 2020
    Applicant: University of Oregon
    Inventors: Karen Guillemin, Annah Rolig, Emily Sweeney
  • Publication number: 20200327437
    Abstract: Spin qubits are situated in mechanical resonators that are acoustically coupled with acoustic waveguides. The acoustic waveguides provide frequency dependent phonon propagation selected so that mechanical resonators adjacent to a selected mechanical resonator are acoustically coupled to the selected mechanical resonator in different acoustic frequency ranges. This configure permits directional transfer of quantum states between spins in spin-mechanical resonator and provides a scalable platform for spin-based quantum computing.
    Type: Application
    Filed: March 5, 2019
    Publication date: October 15, 2020
    Applicant: University of Oregon
    Inventors: Hailin Wang, Mark C. Kuzyk
  • Patent number: 10770699
    Abstract: Electrolytes for use in electric double-layer capacitors (EDLCs; often referred as supercapacitors or ultracapacitors) are disclosed. In one example, the electrolyte comprises viologen in both the anolyte and the catholyte (with bromide). In another example, the electrolyte comprises viologen (in the anolyte) and tetraalkylammonium with bromide (in the catholyte), wherein the tetraalkylammonium is used to achieve solid complexation of bromine in the activated carbon of the cathode. In a third example, a zinc bromine/tetraalkylammonium supercapacitor/battery hybrid is disclosed. Also disclosed is a corrosion resistant bipolar pouch cell that can be used with the electrolyte embodiments described herein.
    Type: Grant
    Filed: May 22, 2017
    Date of Patent: September 8, 2020
    Assignees: The Regents of the University of California, Oregon State University, University of Oregon
    Inventors: Galen D. Stucky, Brian Evanko, Seung Joon Yoo, Jason Lipton, Shannon W. Boettcher, David Xiulei Ji, Xingfeng Wang
  • Publication number: 20200277302
    Abstract: Disclosed herein are polycyclic aromatic compound embodiments and methods of making and using such compounds. In some embodiments, the polycyclic aromatic compounds comprise an indenoindenodi(benzothiophene) skeleton. The polycyclic aromatic compound embodiments can be used in a variety of devices, such as electronic and/or electrooptical devices.
    Type: Application
    Filed: February 28, 2020
    Publication date: September 3, 2020
    Applicant: University of Oregon
    Inventors: Michael Haley, Justin Dressler, Joshua Barker